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Hrishikesh M. Mehta · SciRah

Researcher profile · Semantic Scholar

Hrishikesh M. Mehta

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Hrishikesh M. Mehta — researcher profile on SciRah

h-index: 10
Works: 40
Citations: 719

Most-cited papers

G-CSF and GM-CSF in Neutropenia
Hrishikesh M. Mehta, M. Malandra, S. Corey
2015Journal of Immunology344 citations Open access
Semantic Scholar
Chronic and Acute Models of Retinal Neurodegeneration TrkA Activity Are Neuroprotective whereas p75NTR Activity Is Neurotoxic through a Paracrine Mechanism*
Yu-jing Bai, P. Dergham, H. Nedev, Jing Xu +8 more
2010Journal of Biological Chemistry105 citations Open access
Semantic Scholar
G-CSF, the guardian of granulopoiesis.
Hrishikesh M. Mehta, S. Corey
2021Seminars in Immunology82 citations Open access
Semantic Scholar
Alternatively spliced, truncated GCSF receptor promotes leukemogenic properties and sensitivity to JAK inhibition
Hrishikesh M. Mehta, Muneyoshi Futami, Taly Glaubach, Daniel W. Lee +11 more
2013Leukemia34 citations Open access
Semantic Scholar
Granulocyte colony-stimulating factor receptor T595I (T618I) mutation confers ligand independence and enhanced signaling
Hrishikesh M. Mehta, Taly Glaubach, A. Long, Hannah Lu +6 more
2013Leukemia28 citations Open access
Semantic Scholar
Inducible expression of a disease-associated ELANE mutation impairs granulocytic differentiation, without eliciting an unfolded protein response
B. Garg, Hrishikesh M. Mehta, Borwyn Wang, Ralph Kamel +2 more
2020Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Identification of Critical Residues within the Conserved and Specificity Patches of Nerve Growth Factor Leading to Survival or Differentiation*
S. Mahapatra, Hrishikesh M. Mehta, Sang B. Woo, K. Neet
2009Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Lymphocyte cytosolic protein 1 (L-plastin) I232F mutation impairs granulocytic proliferation and causes neutropenia
Upendra Mahat, B. Garg, Chao-Yie Yang, Hrishikesh M. Mehta +5 more
2022Blood Advances16 citations Open access
Semantic Scholar
Systems Approach to Phagocyte Production and Activation: Neutrophils and Monocytes
Hrishikesh M. Mehta, Taly Glaubach, S. Corey
2014Advances in Experimental Medicine and Biology12 citations Open access
Semantic Scholar
Captopril mitigates splenomegaly and myelofibrosis in the Gata1 low murine model of myelofibrosis
S. Corey, Jyoti K. Jha, Elizabeth A. McCart, W. Rittase +7 more
2018Journal of Cellular and Molecular Medicine11 citations Open access
Semantic Scholar
Alternatively spliced CSF3R isoforms in SRSF2 P95H mutated myeloid neoplasms
Borwyn Wang, Hrishikesh M. Mehta, Srinivasa R. Penumutchu, B. Tolbert +5 more
2022Leukemia9 citations
Semantic Scholar
Mutation, drift and selection in single-driver hematologic malignancy: Example of secondary myelodysplastic syndrome following treatment of inherited neutropenia
T. Wojdyła, Hrishikesh M. Mehta, Taly Glaubach, R. Bertolusso +4 more
2019PLoS Comput. Biol.9 citations Open access
Semantic Scholar
Effect of the unfolded protein response and oxidative stress on mutagenesis in CSF3R: a model for evolution of severe congenital neutropenia to myelodysplastic syndrome/acute myeloid leukemia.
Adya Sapra, R. Jaksik, Hrishikesh M. Mehta, Sara Biesiadny +2 more
2020Mutagenesis6 citations Open access
Semantic Scholar
Cytokine receptor splice variants in hematologic diseases
Borwyn Wang, Hrishikesh M. Mehta
2019Cytokine6 citations Open access
Semantic Scholar
Comparison of Nerve Growth Factor Receptor Binding Models Using Heterodimeric Muteins
Hrishikesh M. Mehta, Sang B. Woo, K. Neet
2012Journal of Neuroscience Research5 citations Open access
Semantic Scholar
Molecular Spectrum of CSF3R variants Correlate with Specific Myeloid Malignancies and Secondary Mutations
V. Adema, C. Hirsch, B. Przychodzen, Y. Nagata +15 more
2018Blood3 citations
Semantic Scholar
Inducible Expression of Mutant ELANE Correlates with Disruption of Differentiation Program, but Not the Unfolded Protein Response
B. Garg, Hrishikesh M. Mehta, Ralph Kamel, M. Horwitz +1 more
2019Blood2 citations Open access
Semantic Scholar
Two SHIPs passing in the middle of the immune system
Seth J. Corey, Hrishikesh M. Mehta, P. Stein
2012European Journal of Immunology2 citations Open access
Semantic Scholar
Lymphocyte Cytosolic Protein 1 I232F Mutation Impairs Granulocytic Proliferation with a G2/M Block in Severe Neutropenia
Upendra Mahat, B. Garg, Hrishikesh M. Mehta, H. Rogers +4 more
2021Blood1 citations Open access
Semantic Scholar
Germline and Somatic Variants of CSF3R Define Distinct Myeloid Neoplasia Syndromes
Tariq Kewan, Hrishikesh M. Mehta, C. Gurnari, W. Bahaj +8 more
2021Blood1 citations Open access
Semantic Scholar
Inherited Neutropenias and Their Insights into Cellular and Developmental Biology
Hrishikesh M. Mehta, S. Corey
20181 citations
Semantic Scholar
Selectivity of Cell Signaling in the Neuronal Response Based on NGF Mutations and Peptidomimetics in the Treatment of Alzheimers Disease
K. Neet, S. Mahapatra, Hrishikesh M. Mehta
20111 citations Open access
Semantic Scholar
Hog1/p38 and ZAKα drive Shwachman-Diamond syndrome and provide targets to improve cell growth
Nozomu Kawashima, N. Prasad, Frank Tedeschi, Hrishikesh M. Mehta +9 more
2026bioRxiv0 citations
Semantic Scholar
Somatic Genetic Rescue Involving CSF3R and Other Novel Phosphothyrosine Kinase Receptor Mutations Occurring in Myeloid Malignancies
Serhan Unlu, Christopher Haddad, D. Dima, Tariq Kewan +11 more
2023Blood0 citations Open access
Semantic Scholar
B‐cell lymphoblastic leukemia in an adolescent with Dravet syndrome
Mohamed Alzobi, C. Hurtz, Hrishikesh M. Mehta, Stefanie M. Thomas +1 more
2023Pediatric Blood & Cancer0 citations Open access
Semantic Scholar
MDS-Associated Splicing Factor Mutations Promote Alternative Splicing of a Differentiation-Impaired CSF3R Isoform
Borwyn Wang, Hrishikesh M. Mehta, S. Corey
2021Blood0 citations
Semantic Scholar
Getting Back to Normal: Correcting SCN by Universal or Precision Strikes.
Hrishikesh M. Mehta, S. Corey
2020Molecular Therapy0 citations Open access
Semantic Scholar
Effect of the Unfolded Protein Response and Oxidative Stress on Mutagenesis of CSF3R a Model of Evolution of Severe Congenital Neutropenia to Myelodysplastic Syndrome/Acute Myeloid Leukemia
Adya Sapra, R. Jaksik, Sara Biesiadny, Hrishikesh M. Mehta +2 more
2019Blood0 citations Open access
Semantic Scholar
The Evaluation of Mefloquine Drug Repurposing on Acute Myeloid Leukemia
J. Phan, B. Garg, Hrishikesh M. Mehta, S. Corey
20180 citations
Semantic Scholar
Identification of Bone Marrow-Derived and Circulating Fibrocytes in Gata1low Mice with Myelofibrosis
A. P. Marquez, Jeffy George, Hrishikesh M. Mehta, R. Day +1 more
20160 citations
Semantic Scholar
Mutations in the Spliceosome Lead to Alternative Splicing of CSF3R in Promoting Myelodysplastic Syndromes
Frances Austin, Hrishikesh M. Mehta, Chong-Hui Cheng, S. Corey
20160 citations
Semantic Scholar
Conditional Expression of Mutant ELANE Produces Unfolded Protein Response but Fails to Promote Cell Death or Differentiation Block: What Is the Mechanism for Severe Congenital Neutropenia?
Hrishikesh M. Mehta, Arighno Das, Ralph Kamel, M. Horwitz +1 more
20160 citations
Semantic Scholar
Abstract B2-50: Stochastic population genetics modeling of the evolution of the myelodysplastic syndrome
T. Wojdyła, Hrishikesh M. Mehta, Taly Glaubach, Thomas O. McDonald +2 more
20150 citations
Semantic Scholar
38 INFINITE-ALLELE BRANCHING PROCESS IN THE EVOLUTION OF THE MYELODYSPLASTIC SYNDROME
T. Wojdyła, Hrishikesh M. Mehta, Thomas O. McDonald, M. Kimmel +1 more
20150 citations
Semantic Scholar
Linking stress granulopoiesis to protein synthesis through GADD34
Hrishikesh M. Mehta, Seth J. Corey
2014Immunology and Cell Biology0 citations Open access
Semantic Scholar
Profound Signaling Abnormalities Due to Cytoplasmic Variants of CSF3R in Patients with Myelodysplastic/Myeloproliferative Syndromes Associated with CSF3R Mutations or Mutations of Splicing Factor U2AF1
Hrishikesh M. Mehta, Hideki Maskishima, M. Futami, W. Kao +4 more
20120 citations
Semantic Scholar
Differentiation-Defective Class IV GCSF Receptor Promotes Resistance to Apoptosis Through Induction of Anti-Apoptotic Bcl-2 Family Proteins
Taly Glaubach, Hrishikesh M. Mehta, S. Corey
20120 citations
Semantic Scholar
Examination of ligand receptor interactions and resulting function using nerve growth factor homodimeric and heterodimeric muteins
Hrishikesh M. Mehta
20100 citations
Semantic Scholar
Design and characterization of a nerve growth factor (NGF) mutein that favors survival over differentiation
Hrishikesh M. Mehta, S. Mahapatra, K. Neet
20090 citations
Semantic Scholar
Generation of a heterodimer of NGF muteins to study the function of the putative TrkA‐p75 heteroreceptor complex
Hrishikesh M. Mehta, K. Neet
20090 citations
Semantic Scholar

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