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M. Ziche · SciRah

Researcher profile · Semantic Scholar

M. Ziche

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M. Ziche — researcher profile on SciRah

h-index: 59
Works: 253
Citations: 15K

Most-cited papers

Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis.
Federica Finetti, A. Basile, Domenica Capasso, S. Di Gaetano +6 more
2012Biochemical Pharmacology107 citations
Semantic Scholar
Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells
Valerio Ciccone, E. Terzuoli, S. Donnini, A. Giachetti +2 more
2018Journal of experimental & clinical cancer research : CR106 citations Open access
Semantic Scholar
VEGF induces signalling and angiogenesis by directing VEGFR2 internalisation through macropinocytosis
Dimitris Basagiannis, Sofia Zografou, C. Murphy, T. Fotsis +5 more
2016Journal of Cell Science105 citations Open access
Semantic Scholar
Aminoflavone, a ligand of the Aryl Hydrocarbon Receptor (AhR), inhibits HIF-1α expression in an AhR-independent fashion
E. Terzuoli, M. Puppo, A. Rapisarda, B. Uranchimeg +4 more
2010Cancer Research101 citations Open access
Semantic Scholar
The natural compound n-butylidenephthalide derived from the volatile oil of Radix Angelica sinensis inhibits angiogenesis in vitro and in vivo
J. Yeh, T. Cindrova-Davies, M. Belleri, L. Morbidelli +9 more
2011Angiogenesis78 citations Open access
Semantic Scholar
Aß peptides accelerate the senescence of endothelial cells in vitro and in vivo, impairing angiogenesis
S. Donnini, R. Solito, Elisa Cetti, F. Corti +5 more
2010The FASEB Journal78 citations
Semantic Scholar
Genetic and pharmacologic inactivation of cannabinoid CB1 receptor inhibits angiogenesis.
S. Pisanti, P. Picardi, Lucia Prota, M. Proto +7 more
2011Blood77 citations Open access
Semantic Scholar
Hydroxytyrosol, a product from olive oil, reduces colon cancer growth by enhancing epidermal growth factor receptor degradation.
E. Terzuoli, A. Giachetti, M. Ziche, S. Donnini
2016Molecular Nutrition & Food Research76 citations Open access
Semantic Scholar
Inhibition of Hypoxia Inducible Factor-1α by Dihydroxyphenylethanol, a Product from Olive Oil, Blocks Microsomal Prostaglandin-E Synthase-1/Vascular Endothelial Growth Factor Expression and Reduces Tumor Angiogenesis
E. Terzuoli, S. Donnini, A. Giachetti, Miguel A. Íñiguez +3 more
2010Clinical Cancer Research71 citations Open access
Semantic Scholar
Mitochondrial aldehyde dehydrogenase-2 activation prevents &bgr;-amyloid-induced endothelial cell dysfunction and restores angiogenesis
R. Solito, F. Corti, Che-Hong Chen, D. Mochly-Rosen +3 more
2013Journal of Cell Science61 citations Open access
Semantic Scholar
Common Protective Strategies in Neurodegenerative Disease: Focusing on Risk Factors to Target the Cellular Redox System
P. Hrelia, G. Sita, M. Ziche, E. Ristori +7 more
2020Oxidative Medicine and Cellular Longevity57 citations Open access
Semantic Scholar
ALDH3A1 Overexpression in Melanoma and Lung Tumors Drives Cancer Stem Cell Expansion, Impairing Immune Surveillance through Enhanced PD-L1 Output
E. Terzuoli, C. Bellan, S. Aversa, Valerio Ciccone +4 more
2019Cancers56 citations Open access
Semantic Scholar
Protective effect of 4-coumaric acid from UVB ray damage in the rabbit eye.
M. Lodovici, S. Caldini, L. Morbidelli, V. Akpan +2 more
2009Toxicology55 citations
Semantic Scholar
Antagonism of Bradykinin B2 Receptor Prevents Inflammatory Responses in Human Endothelial Cells by Quenching the NF-kB Pathway Activation
E. Terzuoli, S. Meini, P. Cucchi, C. Catalani +5 more
2014PLoS ONE53 citations Open access
Semantic Scholar
RETRACTED: Pharmacological Inhibition of Microsomal Prostaglandin E Synthase-1 Suppresses Epidermal Growth Factor Receptor-Mediated Tumor Growth and Angiogenesis
Federica Finetti, E. Terzuoli, E. Bocci, I. Coletta +7 more
2012PLoS ONE51 citations Open access
Semantic Scholar
PGE2/EP3/SRC signaling induces EGFR nuclear translocation and growth through EGFR ligands release in lung adenocarcinoma cells
L. Bazzani, S. Donnini, Federica Finetti, G. Christofori +1 more
2017OncoTarget50 citations Open access
Semantic Scholar
The Syndecan-4/Protein Kinase Cα Pathway Mediates Prostaglandin E2-induced Extracellular Regulated Kinase (ERK) Activation in Endothelial Cells and Angiogenesis in Vivo*
F. Corti, Federica Finetti, M. Ziche, M. Simons
2013Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Characterization of zofenoprilat as an inducer of functional angiogenesis through increased H2S availability
E. Terzuoli, M. Monti, V. Vellecco, M. Bucci +3 more
2015British Journal of Pharmacology40 citations Open access
Semantic Scholar
ALDH2 Activity Reduces Mitochondrial Oxygen Reserve Capacity in Endothelial Cells and Induces Senescence Properties
Ginevra Nannelli, Erika Terzuoli, V. Giorgio, S. Donnini +4 more
2018Oxidative Medicine and Cellular Longevity39 citations Open access
Semantic Scholar
Inhibition of cell cycle progression by the hydroxytyrosol–cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells
E. Terzuoli, G. Nannelli, M. Frosini, A. Giachetti +2 more
2017OncoTarget39 citations Open access
Semantic Scholar
mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity
Federica Finetti, E. Terzuoli, A. Giachetti, R. Santi +5 more
2015Endocrine-Related Cancer39 citations Open access
Semantic Scholar
Sulfhydryl Angiotensin-Converting Enzyme Inhibitor Promotes Endothelial Cell Survival through Nitric-Oxide Synthase, Fibroblast Growth Factor-2, and Telomerase Cross-Talk
S. Donnini, E. Terzuoli, M. Ziche, L. Morbidelli
2010Journal of Pharmacology and Experimental Therapeutics39 citations
Semantic Scholar
The sulphydryl containing ACE inhibitor Zofenoprilat protects coronary endothelium from Doxorubicin-induced apoptosis.
M. Monti, E. Terzuoli, M. Ziche, L. Morbidelli
2013Pharmacological Research36 citations
Semantic Scholar
Targeting endothelial-to-mesenchymal transition: the protective role of hydroxytyrosol sulfate metabolite
E. Terzuoli, G. Nannelli, A. Giachetti, L. Morbidelli +2 more
2019European Journal of Nutrition35 citations
Semantic Scholar
Formulation of liposomes functionalized with Lotus lectin and effective in targeting highly proliferative cells.
C. della Giovampaola, A. Capone, L. Ermini, P. Lupetti +9 more
2017Biochimica et Biophysica Acta - General Subjects35 citations Open access
Semantic Scholar
The isoflavone metabolite 6-methoxyequol inhibits angiogenesis and suppresses tumor growth
S. Bellou, Evdoxia Karali, E. Bagli, N. Al-Maharik +5 more
2012Molecular Cancer35 citations Open access
Semantic Scholar
New Insights Into Blood-Brain Barrier Maintenance: The Homeostatic Role of β-Amyloid Precursor Protein in Cerebral Vasculature
E. Ristori, S. Donnini, M. Ziche
2020Frontiers in Physiology34 citations Open access
Semantic Scholar
H2S dependent and independent anti-inflammatory activity of zofenoprilat in cells of the vascular wall.
M. Monti, E. Terzuoli, M. Ziche, L. Morbidelli
2016Pharmacological Research34 citations
Semantic Scholar
Prostaglandin E2 transactivates the colony‐stimulating factor‐1 receptor and synergizes with colony‐stimulating factor‐1 in the induction of macrophage migration via the mitogen‐activated protein kinase ERK1/2
G. Digiacomo, M. Ziche, Persio Dello Sbarba, S. Donnini +1 more
2015The FASEB Journal34 citations
Semantic Scholar
The soluble guanylyl cyclase inhibitor NS-2028 reduces vascular endothelial growth factor-induced angiogenesis and permeability.
L. Morbidelli, A. Pyriochou, S. Filippi, I. Vasileiadis +8 more
2010American Journal of Physiology. Regulatory Integrative and Comparative Physiology34 citations
Semantic Scholar
Targeting endothelial cell metabolism for cardio-protection from the toxicity of antitumor agents
L. Morbidelli, S. Donnini, M. Ziche
2016Cardio-Oncology31 citations Open access
Semantic Scholar
ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL-8/Notch signaling cascade
Valerio Ciccone, E. Terzuoli, E. Ristori, A. Filippelli +3 more
2022International Journal of Molecular Medicine30 citations Open access
Semantic Scholar
PKCε ACTIVATION PROMOTES FGF-2 EXOCYTOSIS AND INDUCES ENDOTHELIAL CELL PROLIFERATION AND SPROUTING
M. Monti, S. Donnini, L. Morbidelli, A. Giachetti +3 more
2013Journal of Molecular and Cellular Cardiology30 citations Open access
Semantic Scholar
EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity
S. Donnini, Federica Finetti, E. Terzuoli, A. Giachetti +5 more
2012Oncogene30 citations Open access
Semantic Scholar
PGE2 mediates EGFR internalization and nuclear translocation via caveolin endocytosis promoting its transcriptional activity and proliferation in human NSCLC cells
L. Bazzani, S. Donnini, A. Giachetti, G. Christofori +1 more
2018OncoTarget29 citations Open access
Semantic Scholar
Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and −186 expression: Novel mechanism of VEGF modulation in prostate cancer
E. Terzuoli, S. Donnini, Federica Finetti, G. Nesi +5 more
2016OncoTarget29 citations Open access
Semantic Scholar
How to conjugate the stemness marker ALDH1A1 with tumor angiogenesis, progression, and drug resistance
Valerio Ciccone, L. Morbidelli, M. Ziche, S. Donnini
2020Cancer Drug Resistance27 citations Open access
Semantic Scholar
Monitoring Endothelial and Tissue Responses to Cobalt Ferrite Nanoparticles and Hybrid Hydrogels
Federica Finetti, E. Terzuoli, S. Donnini, M. Uva +2 more
2016PLoS ONE27 citations Open access
Semantic Scholar
RNA‐mediated gene silencing of FUT1 and FUT2 influences expression and activities of bovine and human fucosylated nucleolin and inhibits cell adhesion and proliferation
D. Palumberi, S. Aldi, L. Ermini, M. Ziche +3 more
2010Journal of Cellular Biochemistry26 citations
Semantic Scholar
Vimentin expression influences flow dependent VASP phosphorylation and regulates cell migration and proliferation.
Natalie Lund, D. Henrion, P. Tiede, M. Ziche +2 more
2010Biochemical and Biophysical Research Communications - BBRC24 citations
Semantic Scholar
Sex-tailored pharmacology and COVID-19: Next steps towards appropriateness and health equity
A. Spini, Valentina Giudice, V. Brancaleone, M. Morgese +7 more
2021Pharmacological Research23 citations Open access
Semantic Scholar
Evidence of β-blockers drug repurposing for the treatment of triple negative breast cancer: A systematic review.
A. Spini, G. Roberto, R. Gini, C. Bartolini +4 more
2019Neoplasma (Bratislava)23 citations Open access
Semantic Scholar
Bradykinin B2 Receptor Contributes to Inflammatory Responses in Human Endothelial Cells by the Transactivation of the Fibroblast Growth Factor Receptor FGFR-1
E. Terzuoli, F. Corti, G. Nannelli, A. Giachetti +2 more
2018International Journal of Molecular Sciences23 citations Open access
Semantic Scholar
Miniaturizing VEGF: Peptides mimicking the discontinuous VEGF receptor-binding site modulate the angiogenic response
L. De Rosa, Federica Finetti, D. Diana, R. Di Stasi +6 more
2016Scientific Reports22 citations Open access
Semantic Scholar
Safety of Anti-Angiogenic Drugs in Pediatric Patients with Solid Tumors: A Systematic Review and Meta-Analysis
A. Spini, Valerio Ciccone, P. Rosellini, M. Ziche +3 more
2022Cancers20 citations Open access
Semantic Scholar
Repurposing of drugs for triple negative breast cancer: an overview
A. Spini, S. Donnini, P. Pantziarka, S. Crispino +1 more
2020ecancermedicalscience20 citations Open access
Semantic Scholar
Endothelial Aldehyde Dehydrogenase 2 as a Target to Maintain Vascular Wellness and Function in Ageing
G. Nannelli, M. Ziche, S. Donnini, L. Morbidelli
2020Biomedicines19 citations Open access
Semantic Scholar
Amyloid-β Precursor Protein APP Down-Regulation Alters Actin Cytoskeleton-Interacting Proteins in Endothelial Cells
E. Ristori, Vittoria Cicaloni, L. Salvini, Laura Tinti +5 more
2020Cells17 citations Open access
Semantic Scholar
ALDH1A1 confers resistance to RAF/MEK inhibitors in melanoma cells by maintaining stemness phenotype and activating PI3K/AKT signaling.
Valerio Ciccone, Vittoria Simonis, Cinzia Del Gaudio, C. Cucini +3 more
2024Biochemical Pharmacology16 citations Open access
Semantic Scholar
Correction to: Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells
Valerio Ciccone, E. Terzuoli, S. Donnini, A. Giachetti +2 more
2019Journal of experimental & clinical cancer research : CR14 citations Open access
Semantic Scholar

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L. Morbidelli×23
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L. Morbidelli — researcher profile on SciRah
E. Terzuoli×20
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Federica Finetti

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Valerio Ciccone — researcher profile on SciRah

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F. Corti — researcher profile on SciRah

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E. Ristori — researcher profile on SciRah

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M. Monti — researcher profile on SciRah

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G. Nannelli — researcher profile on SciRah

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