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A. Lymperopoulos · SciRah

Researcher profile · Semantic Scholar

A. Lymperopoulos

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A. Lymperopoulos — researcher profile on SciRah

h-index: 36
Works: 188
Citations: 4,416

Most-cited papers

Short-Chain Fatty Acid Receptors and Cardiovascular Function
A. Lymperopoulos, M. Suster, J. Borges
2022International Journal of Molecular Sciences101 citations Open access
Semantic Scholar
&bgr;-Arrestin2 Improves Post–Myocardial Infarction Heart Failure via Sarco(endo)plasmic Reticulum Ca2+-ATPase–Dependent Positive Inotropy in Cardiomyocytes
K. McCrink, J. Maning, A. Vu, Malika Jafferjee +6 more
2017HYPERTENSION76 citations Open access
Semantic Scholar
Signaling and function of cardiac autonomic nervous system receptors: Insights from the GPCR signalling universe
A. Lymperopoulos, Natalie Cora, J. Maning, Ava R. Brill +1 more
2021The FEBS Journal51 citations
Semantic Scholar
GPCRs of adrenal chromaffin cells & catecholamines: The plot thickens.
A. Lymperopoulos, Ava R. Brill, K. McCrink
2016International Journal of Biochemistry and Cell Biology42 citations
Semantic Scholar
Chemically synthesized Secoisolariciresinol diglucoside (LGM2605) improves mitochondrial function in cardiac myocytes and alleviates septic cardiomyopathy
D. Kokkinaki, Matthew Hoffman, Charikleia Kalliora, I. Kyriazis +12 more
2019Journal of Molecular and Cellular Cardiology41 citations Open access
Semantic Scholar
Deletion of Osteopontin Enhances β2-Adrenergic Receptor-Dependent Anti-Fibrotic Signaling in Cardiomyocytes
Celina M. Pollard, V. Desimine, S. L. Wertz, Arianna Perez +5 more
2019International Journal of Molecular Sciences38 citations Open access
Semantic Scholar
Sympatholytic Mechanisms for the Beneficial Cardiovascular Effects of SGLT2 Inhibitors: A Research Hypothesis for Dapagliflozin’s Effects in the Adrenal Gland
A. Lymperopoulos, J. Borges, Natalie Cora, Anastasiya Sizova
2021International Journal of Molecular Sciences37 citations Open access
Semantic Scholar
Novel Insights into the Crosstalk between Mineralocorticoid Receptor and G Protein-Coupled Receptors in Heart Adverse Remodeling and Disease
B. M. Parker, S. L. Wertz, Celina M. Pollard, V. Desimine +3 more
2018International Journal of Molecular Sciences37 citations Open access
Semantic Scholar
Regulator of G-Protein Signaling-4 Attenuates Cardiac Adverse Remodeling and Neuronal Norepinephrine Release-Promoting Free Fatty Acid Receptor FFAR3 Signaling
A. Carbone, J. Borges, M. Suster, Anastasiya Sizova +3 more
2022International Journal of Molecular Sciences36 citations Open access
Semantic Scholar
Arrestins in the Cardiovascular System: An Update.
A. Lymperopoulos
2018Progress in Molecular Biology and Translational Science35 citations
Semantic Scholar
Biased agonism/antagonism at the AngII‐AT1 receptor: Implications for adrenal aldosterone production and cardiovascular therapy
J. Maning, S. Negussie, Michelle A. Clark, A. Lymperopoulos
2017Pharmacological Research33 citations
Semantic Scholar
Antagonistic Roles of GRK2 and GRK5 in Cardiac Aldosterone Signaling Reveal GRK5-Mediated Cardioprotection via Mineralocorticoid Receptor Inhibition
J. Maning, K. McCrink, Celina M. Pollard, V. Desimine +8 more
2020International Journal of Molecular Sciences30 citations Open access
Semantic Scholar
Biased Agonism/Antagonism of Cardiovascular GPCRs for Heart Failure Therapy.
V. Desimine, K. McCrink, B. M. Parker, S. L. Wertz +2 more
2018International Review of Cell and Molecular Biology30 citations
Semantic Scholar
Angiotensin receptor blocker drugs and inhibition of adrenal beta-arrestin-1-dependent aldosterone production: Implications for heart failure therapy
A. Lymperopoulos, Beatrix Aukszi
2017World Journal of Cardiology29 citations Open access
Semantic Scholar
GRK2 Up-Regulation Creates a Positive Feedback Loop for Catecholamine Production in Chromaffin Cells.
Malika Jafferjee, Thairy Reyes Valero, Christine Marrero, K. McCrink +2 more
2016Molecular Endocrinology29 citations Open access
Semantic Scholar
Adrenal angiotensin II type 1 receptor biased signaling: The case for "biased" inverse agonism for effective aldosterone suppression.
K. Ferraino, Natalie Cora, Celina M. Pollard, Anastasiya Sizova +2 more
2021Cellular Signalling24 citations
Semantic Scholar
Structure–activity relationship study of angiotensin II analogs in terms of β‐arrestin‐dependent signaling to aldosterone production
T. R. Valero, E. Sturchler, Malika Jafferjee, G. Rengo +5 more
2016Pharmacology Research & Perspectives24 citations Open access
Semantic Scholar
Impact of Aldosterone on the Failing Myocardium: Insights from Mitochondria and Adrenergic Receptors Signaling and Function
M. Guitart-Mampel, Pedro Urquiza, J. Borges, A. Lymperopoulos +1 more
2021Cells23 citations Open access
Semantic Scholar
Not all arrestins are created equal: Therapeutic implications of the functional diversity of the β-arrestins in the heart
A. Lymperopoulos, S. L. Wertz, Celina M. Pollard, V. Desimine +2 more
2019World Journal of Cardiology22 citations Open access
Semantic Scholar
The place of ARBs in heart failure therapy: is aldosterone suppression the key?
U. Markan, S. Pasupuleti, Celina M. Pollard, Arianna Perez +2 more
2019Therapeutic Advances in Cardiovascular Disease19 citations Open access
Semantic Scholar
Cardiac βarrestin2 Improves Contractility and Adverse Remodeling in Heart Failure, But Is Underexpressed in Humans.
K. McCrink, J. Maning, A. Vu, Malika Jafferjee +6 more
2017Journal of the American College of Cardiology18 citations Open access
Semantic Scholar
Differential Modulation of Catecholamine and Adipokine Secretion by the Short Chain Fatty Acid Receptor FFAR3 and α2-Adrenergic Receptors in PC12 Cells
Deepika Nagliya, Teresa Baggio Lopez, G. Del Calvo, Renee A. Stoicovy +3 more
2024International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
RGS Proteins and Cardiovascular Angiotensin II Signaling: Novel Opportunities For Therapeutic Targeting
A. Lymperopoulos, J. Borges, Renee A. Stoicovy
2023Biochemical Pharmacology17 citations Open access
Semantic Scholar
Cardiovascular angiotensin II type 1 receptor biased signalling: Focus on non-Gq-, non-βarrestin-dependent signalling.
A. Lymperopoulos, J. Borges, A. Carbone, Natalie Cora +1 more
2021Pharmacological Research16 citations
Semantic Scholar
Methotrexate for Cornual Ectopic Pregnancy
B. M. Parker, Anupam K. Gupta, A. Lymperopoulos, J. Parker
2020Cureus16 citations Open access
Semantic Scholar
β Adrenergic Receptor Kinase C-Terminal Peptide Gene-Therapy Improves β2-Adrenergic Receptor-Dependent Neoangiogenesis after Hindlimb Ischemia
A. Cannavo, D. Liccardo, A. Lymperopoulos, G. Gambino +6 more
2016Journal of Pharmacology and Experimental Therapeutics16 citations Open access
Semantic Scholar
Cyclic Adenosine Monophosphate in Cardiac and Sympathoadrenal GLP-1 Receptor Signaling: Focus on Anti-Inflammatory Effects
A. Lymperopoulos, J. Borges, Renee A. Stoicovy
2024Pharmaceutics15 citations Open access
Semantic Scholar
A case report: Pharmacology and resistance patterns of three generations of ALK inhibitors in metastatic inflammatory myofibroblastic sarcoma
B. M. Parker, J. Parker, A. Lymperopoulos, V. Konda
2018Journal of Oncology Pharmacy Practice15 citations
Semantic Scholar
Cyclic adenosine monophosphate critically modulates cardiac GLP-1 receptor’s anti-inflammatory effects
Renee A. Stoicovy, Natalie Cora, Arianna Perez, Deepika Nagliya +6 more
2024Inflammation Research14 citations
Semantic Scholar
β1-adrenoceptor Arg389Gly polymorphism confers differential β-arrestin-binding tropism in cardiac myocytes.
K. McCrink, Ava R. Brill, Malika Jafferjee, T. R. Valero +4 more
2016Pharmacogenomics (London)14 citations
Semantic Scholar
Carvedilol Selectively Stimulates βArrestin2-Dependent SERCA2a Activity in Cardiomyocytes to Augment Contractility
J. Maning, V. Desimine, Celina M. Pollard, Jennifer Ghandour +1 more
2022International Journal of Molecular Sciences13 citations Open access
Semantic Scholar
GRK2 Regulates α2-Adrenergic Receptor–Dependent Catecholamine Release in Human Adrenal Chromaffin Cells
A. Cannavo, D. Liccardo, A. Lymperopoulos, M. Santangelo +7 more
2017Journal of the American College of Cardiology13 citations Open access
Semantic Scholar
Autonomic Nervous System Regulation of Epicardial Adipose Tissue: Potential Roles for Regulator of G Protein Signaling-4
A. Carbone, G. Del Calvo, Deepika Nagliya, K. Sharma +1 more
2022Current Issues in Molecular Biology12 citations Open access
Semantic Scholar
Nicotine-induced adrenal beta-arrestin1 upregulation mediates tobacco-related hyperaldosteronism leading to cardiac dysfunction
Natalie Cora, Jennifer Ghandour, Celina M. Pollard, V. Desimine +4 more
2020World Journal of Cardiology12 citations Open access
Semantic Scholar
Nicotine Diminishes Alpha2-Adrenergic Receptor-Dependent Protection Against Oxidative Stress in H9c2 Cardiomyocytes
G. Del Calvo, Celina M. Pollard, Teresa Baggio Lopez, J. Borges +2 more
2024Drug Design, Development and Therapy11 citations Open access
Semantic Scholar
GRK2-Mediated Crosstalk Between β-Adrenergic and Angiotensin II Receptors Enhances Adrenocortical Aldosterone Production In Vitro and In Vivo
Celina M. Pollard, Jennifer Ghandour, Natalie Cora, Arianna Perez +7 more
2020International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Osteopontin and LDLR Are Upregulated in Hearts of Sudden Cardiac Death Victims With Heart Failure With Preserved Ejection Fraction and Diabetes Mellitus
Mausam Patel, D. Rodriguez, Keyvan Yousefi, Krista John‐Williams +8 more
2020Frontiers in Cardiovascular Medicine11 citations Open access
Semantic Scholar
Clinical pharmacogenomics of carvedilol: the stereo-selective metabolism angle.
B. M. Parker, S. Rogers, A. Lymperopoulos
2018Pharmacogenomics (London)11 citations Open access
Semantic Scholar
Clinical pharmacology of cardiac cyclic AMP in human heart failure: too much or too little?
A. Lymperopoulos
2023Expert Review of Clinical Pharmacology10 citations
Semantic Scholar
Adrenal βarrestin1 targeting for tobacco–associated cardiac dysfunction treatment: Aldosterone production as the mechanistic link
M. E. Solesio, E. Mitaishvili, A. Lymperopoulos
2019Pharmacology Research & Perspectives10 citations Open access
Semantic Scholar
Deletion of Osteopontin Enhances b2-Adrenergic Receptor-Dependent Anti-Fibrotic Signaling in Cardiomyocytes
Celina M. Pollard, V. Desimine, S. L. Wertz, Arianna Perez +5 more
201910 citations Open access
Semantic Scholar
Cardiac RGS Proteins in Human Heart Failure and Atrial Fibrillation: Focus on RGS4
J. Borges, M. Suster, A. Lymperopoulos
2023International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Adrenal G protein-coupled receptors and the failing heart: A long-distance, yet intimate affair
J. Borges, K. Ferraino, Natalie Cora, Deepika Nagliya +3 more
2021Journal of Cardiovascular Pharmacology9 citations Open access
Semantic Scholar
Sustained GRK2-dependent CREB activation is essential for α2-adrenergic receptor-induced PC12 neuronal differentiation.
G. Karkoulias, K. McCrink, J. Maning, Celina M. Pollard +6 more
2020Cellular Signalling9 citations
Semantic Scholar
Co-IP assays for measuring GPCR-arrestin interactions.
S. L. Wertz, V. Desimine, J. Maning, K. McCrink +1 more
2019Methods in Cell Biology7 citations
Semantic Scholar
Hypothesis: Paroxetine, a G Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitor Reduces Morbidity and Mortality in Patients With Heart Failure.
J. Powell, Emanuel Ebin, S. Borzak, A. Lymperopoulos +1 more
2017Journal of Cardiovascular Pharmacology and Therapeutics7 citations
Semantic Scholar
Metabolomics Profiling of Epicardial Adipose Tissue: MESA and the Rotterdam Study
I. Neeland, Fang Zhu, Gonçalo Graça, A. Lymperopoulos +7 more
2025Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease6 citations Open access
Semantic Scholar
GRK5 is an essential co-repressor of the cardiac mineralocorticoid receptor and is selectively induced by finerenone
Celina M. Pollard, M. Suster, Natalie Cora, A. Carbone +1 more
2022World Journal of Cardiology6 citations Open access
Semantic Scholar
Gut microbiota alterations in acute myocardial infarction: (diabetic) context is everything
A. Lymperopoulos
2023Annals of Translational Medicine5 citations Open access
Semantic Scholar
Cardiovascular GPCR regulation by regulator of G protein signaling proteins.
A. Lymperopoulos, M. Suster, J. Borges
2022Progress in Molecular Biology and Translational Science4 citations
Semantic Scholar

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J. Maning×15
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J. Maning — researcher profile on SciRah
J. Borges×13
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K. McCrink×13
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Celina M. Pollard×13
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V. Desimine — researcher profile on SciRah

Natalie Cora×11

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B. M. Parker×9

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M. Suster — researcher profile on SciRah

Ava R. Brill×7

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