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P. Ruggiero · SciRah

Researcher profile · Semantic Scholar

P. Ruggiero

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P. Ruggiero — researcher profile on SciRah

h-index: 28
Works: 77
Citations: 2,307

Most-cited papers

Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus
F. Bagnoli, M. Fontana, E. Soldaini, R. Mishra +36 more
2015Proceedings of the National Academy of Sciences of the United States of America178 citations Open access
Semantic Scholar
Streptococcus pneumoniae Pilus Subunits Protect Mice against Lethal Challenge
Claudia Gianfaldoni, S. Censini, M. Hilleringmann, M. Moschioni +7 more
2006Infection and Immunity145 citations Open access
Semantic Scholar
IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease
P. Bossù, D. Neumann, E. Del Giudice, A. Ciaramella +9 more
2003Proceedings of the National Academy of Sciences of the United States of America133 citations Open access
Semantic Scholar
Mutants of the Escherichia coli heat-labile enterotoxin as safe and strong adjuvants for intranasal delivery of vaccines
S. Peppoloni, P. Ruggiero, M. Contorni, M. Morandi +4 more
2003Expert Review of Vaccines110 citations Open access
Semantic Scholar
Therapeutic Vaccination against Helicobacter pylori in the Beagle Dog Experimental Model: Safety, Immunogenicity, and Efficacy
G. Rossi, P. Ruggiero, S. Peppoloni, Laura Pancotto +9 more
2004Infection and Immunity107 citations Open access
Semantic Scholar
Plant polyphenols inhibit VacA, a toxin secreted by the gastric pathogen Helicobacter pylori
F. Tombola, Silvia Campello, L. De Luca, P. Ruggiero +3 more
2003FEBS Letters95 citations Open access
Semantic Scholar
Helicobacter pylori and inflammation.
P. Ruggiero
2010Current pharmaceutical design92 citations
Semantic Scholar
Use of probiotics in the fight against Helicobacter pylori.
P. Ruggiero
2014World Journal of Gastrointestinal Pathophysiology89 citations Open access
Semantic Scholar
Helicobacter pylori CagA: From Pathogenic Mechanisms to Its Use as an Anti-Cancer Vaccine
M. Stein, P. Ruggiero, R. Rappuoli, F. Bagnoli
2013Frontiers in Immunology89 citations Open access
Semantic Scholar
Efficacy, immunogenicity, and safety of a parenteral vaccine against Helicobacter pylori in healthy volunteers challenged with a Cag-positive strain: a randomised, placebo-controlled phase 1/2 study.
P. Malfertheiner, M. Selgrad, T. Wex, Benedetta Romi +13 more
2018The Lancet Gastroenterology and Hepatology83 citations
Semantic Scholar
Red wine and green tea reduce H pylori- or VacA-induced gastritis in a mouse model.
P. Ruggiero, G. Rossi, F. Tombola, Laura Pancotto +3 more
2007World Journal of Gastroenterology70 citations Open access
Semantic Scholar
Inhibitors of Helicobacter pylori ATPase Cagalpha block CagA transport and cag virulence.
M. Hilleringmann, W. Pansegrau, M. Doyle, Susan Kaufman +4 more
2006Microbiology67 citations Open access
Semantic Scholar
The quest for a vaccine against Helicobacter pylori: how to move from mouse to man?
P. Ruggiero, S. Peppoloni, R. Rappuoli, G. Del Giudice
2003Microbes and infection66 citations Open access
Semantic Scholar
Enhanced mucosal and systemic immune responses to Helicobacter pylori antigens through mucosal priming followed by systemic boosting immunizations
M. Vajdy, Manmohan Singh, M. Ugozzoli, M. Briones +8 more
2003Immunology64 citations Open access
Semantic Scholar
Transfected type II interleukin-1 receptor impairs responsiveness of human keratinocytes to interleukin-1.
P. Bossù, U. Visconti, P. Ruggiero, G. Macchia +6 more
1995American Journal of Pathology58 citations
Semantic Scholar
The Helicobacter pylori VacA cytotoxin activates RBL‐2H3 cells by inducing cytosolic calcium oscillations
M. de Bernard, A. Cappon, Laura Pancotto, P. Ruggiero +3 more
2004Cellular Microbiology54 citations Open access
Semantic Scholar
Staphylococcus aureus-dependent septic arthritis in murine knee joints: local immune response and beneficial effects of vaccination
A. Corrado, Paolo Donato, Silvia Maccari, Raffaella Cecchi +15 more
2016Scientific Reports52 citations Open access
Semantic Scholar
RrgB321, a Fusion Protein of the Three Variants of the Pneumococcal Pilus Backbone RrgB, Is Protective In Vivo and Elicits Opsonic Antibodies
C. Harfouche, Sara Filippini, Claudia Gianfaldoni, P. Ruggiero +21 more
2011Infection and Immunity47 citations Open access
Semantic Scholar
The Two Variants of the Streptococcus pneumoniae Pilus 1 RrgA Adhesin Retain the Same Function and Elicit Cross-Protection In Vivo
M. Moschioni, Carla Emolo, M. Biagini, Silvia Maccari +10 more
2010Infection and Immunity45 citations Open access
Semantic Scholar
Helicobacter pylori infection: what's new
P. Ruggiero
2012Current Opinion in Infectious Diseases44 citations
Semantic Scholar
Persistence of mucosal and systemic immune responses following sublingual immunization.
Donatella Negri, A. Riccomi, D. Pinto, S. Vendetti +5 more
2010Vaccine43 citations
Semantic Scholar
In vivo mucosal delivery of bioactive human interleukin 1 receptor antagonist produced by Streptococcus gordonii
S. Ricci, G. Macchia, P. Ruggiero, T. Maggi +7 more
2003BMC Biotechnology40 citations Open access
Semantic Scholar
Cholera Toxin and Escherichia coli Heat-Labile Enterotoxin, but Not Their Nontoxic Counterparts, Improve the Antigen-Presenting Cell Function of Human B Lymphocytes
Donatella Negri, D. Pinto, S. Vendetti, M. Patrizio +5 more
2009Infection and Immunity35 citations Open access
Semantic Scholar
Polyphenols Reduce Gastritis Induced by Helicobacter pylori Infection or VacA Toxin Administration in Mice
P. Ruggiero, Francesco Tombola, G. Rossi, Laura Pancotto +3 more
2006Antimicrobial Agents and Chemotherapy35 citations
Semantic Scholar
Glycosylation enhances functional stability of the chemotactic cytokine CCL2.
P. Ruggiero, S. Flati, V. Di Cioccio, G. Maurizi +6 more
2003European Cytokine Network35 citations
Semantic Scholar
A dominant negative RAS-specific guanine nucleotide exchange factor reverses neoplastic phenotype in K-ras transformed mouse fibroblasts
P. Bossù, M. Vanoni, Valeria Wanke, M. Cesaroni +9 more
2000Oncogene34 citations Open access
Semantic Scholar
Immunization with the RrgB321 fusion protein protects mice against both high and low pilus-expressing Streptococcus pneumoniae populations.
M. Moschioni, Gabriella de Angelis, C. Harfouche, Esmeralda Bizzarri +7 more
2012Vaccine30 citations
Semantic Scholar
Exogenous sialic acid transport contributes to group B streptococcus infection of mucosal surfaces.
Alfredo Pezzicoli, P. Ruggiero, F. Amerighi, J. Telford +1 more
2012Journal of Infectious Diseases28 citations Open access
Semantic Scholar
Helicobacter pylori Infection Negatively Influences Pregnancy Outcome in a Mouse Model
G. Rossi, S. Romagnoli, L. Lauretti, Laura Pancotto +4 more
2004Helicobacter27 citations
Semantic Scholar
Structural and Functional Characterization of the Streptococcus pneumoniae RrgB Pilus Backbone D1 Domain*
M. Gentile, Sara Melchiorre, Carla Emolo, M. Moschioni +11 more
2011Journal of Biological Chemistry26 citations Open access
Semantic Scholar
Expression of the Streptococcus pneumoniae pilus-1 undergoes on and off switching during colonization in mice
Laura Pancotto, Gabriella de Angelis, Esmeralda Bizzarri, M. Barocchi +3 more
2013Scientific Reports24 citations Open access
Semantic Scholar
Mapping of receptor binding sites on IL-1 beta by reconstruction of IL-1ra-like domains.
D. Boraschi, Paola Bossù, P. Ruggiero, A. Tagliabue +14 more
1995Journal of Immunology24 citations Open access
Semantic Scholar
Sortase A Confers Protection against Streptococcus pneumoniae in Mice
Claudia Gianfaldoni, Silvia Maccari, Laura Pancotto, G. Rossi +8 more
2009Infection and Immunity21 citations Open access
Semantic Scholar
Protective effect of Group B Streptococcus type-III polysaccharide conjugates against maternal colonization, ascending infection and neonatal transmission in rodent models
E. Chiarot, Angela Spagnuolo, Silvia Maccari, Eleonora Naimo +10 more
2018Scientific Reports18 citations Open access
Semantic Scholar
Mucosal delivery of anti-inflammatory IL-1Ra by sporulating recombinant bacteria
Stefano Porzio, P. Bossù, P. Ruggiero, D. Boraschi +1 more
2004BMC Biotechnology18 citations Open access
Semantic Scholar
Intranasal administration of the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei with the modified heat-labile toxin of Escherichia coli (LTK63) induces a complete protection against malaria challenge.
Jackeline F. Romero, Annalisa Ciabattini, P. Guillaume, Géraldine Frank +5 more
2009Vaccine17 citations
Semantic Scholar
Paediatric obstructive sleep apnoea syndrome (OSAS) is associated with tonsil colonisation by Streptococcus pyogenes
Elisa Viciani, F. Montagnani, Simona Tavarini, G. Tordini +12 more
2016Scientific Reports16 citations Open access
Semantic Scholar
Effect of heparin binding on Helicobacter pylori resistance to serum.
J. Dubreuil, P. Ruggiero, R. Rappuoli, G. Del Giudice
2004Journal of Medical Microbiology15 citations Open access
Semantic Scholar
Balance between autocrine interleukin-1beta and caspases defines life versus death of polymorphonuclear cells.
P. Bossù, E. Del Grosso, M. Cesaroni, G. Maurizi +5 more
2001European Cytokine Network14 citations
Semantic Scholar
Identification of a Monoclonal Antibody Against Pneumococcal Pilus 1 Ancillary Protein Impairing Bacterial Adhesion to Human Epithelial Cells.
F. Amerighi, M. Valeri, D. Donnarumma, Silvia Maccari +10 more
2016Journal of Infectious Diseases13 citations
Semantic Scholar
Helicobacter pylori: A Brief History of a Still Lacking Vaccine
P. Ruggiero, S. Censini
201413 citations Open access
Semantic Scholar
Phosphorylated epitopes of neurofilaments have been conserved during chordate evolution.
Caterina Mencarelli, M. Bugnoli, Mario Contorni, A. Moscatelli +2 more
1987Biochemical and Biophysical Research Communications - BBRC13 citations
Semantic Scholar
New strategies for the prevention and treatment of Helicobacter pylori infection
R. Rappuoli, D. Berti, S. Peppoloni, G. Del Giudice +1 more
2002Expert Opinion on Investigational Drugs12 citations Open access
Semantic Scholar
Expression of cytokeratin No. 19 polypeptide in genital papillomavirus lesions.
P. Leoncini, R. Petracca, P. Ruggiero, M. Cintorino +3 more
1990Gynecologic and Obstetric Investigation10 citations
Semantic Scholar
Use of Antibodies Against A Synthetic Peptide of the E6 Protein of Human Papillomavirus (Hpv) Type 16 For the Diagnosis of Genital Hpv Lesions
P. Tosi, V. Pallini, M. Cintorino, M. Bugnoli +9 more
1993Cytopathology8 citations
Semantic Scholar
Antibody‐dependent macrophage‐mediated activity against Helicobacter pylori in the absence of complement
S. Peppoloni, Silvia Mancianti, G. Volpini, S. Nuti +4 more
2002European Journal of Immunology7 citations Open access
Semantic Scholar
Prevalence of M75 Streptococcus pyogenes Strains Harboring slaA Gene in Patients Affected by Pediatric Obstructive Sleep Apnea Syndrome in Central Italy
Elisa Viciani, F. Montagnani, G. Tordini, Antonio Romano +4 more
2017Frontiers in Microbiology6 citations Open access
Semantic Scholar
CagL from Helicobacter pylori has ADP-ribosylation activity and exerts partial protective efficacy in mice.
E. Talluri, Laura Pancotto, P. Ruggiero, M. Scarselli +1 more
2017Archives of Biochemistry and Biophysics6 citations
Semantic Scholar
Innate Response Activator (IRA) B Cells Reside in Human Tonsils and Internalize Bacteria In Vitro
N. Chiappini, R. Cantisani, Laura Pancotto, P. Ruggiero +7 more
2015PLoS ONE6 citations Open access
Semantic Scholar
Models for bacterial infectious diseases: Helicobacter pylori
P. Ruggiero, A. Alloueche, R. Rappuoli, G. Del Giudice
20044 citations
Semantic Scholar

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G. Del Giudice×20
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G. Del Giudice — researcher profile on SciRah
R. Rappuoli×14
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R. Rappuoli — researcher profile on SciRah
Laura Pancotto×12
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Laura Pancotto — researcher profile on SciRah
Silvia Maccari×8
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M. Moschioni — researcher profile on SciRah

V. Masignani×7

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V. Masignani — researcher profile on SciRah

W. Pansegrau×6

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W. Pansegrau — researcher profile on SciRah

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M. Barocchi — researcher profile on SciRah

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P. Bossù — researcher profile on SciRah

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D. Boraschi — researcher profile on SciRah

S. Peppoloni×6

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S. Peppoloni — researcher profile on SciRah

Claudia Gianfaldoni×5

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Claudia Gianfaldoni — researcher profile on SciRah