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R. Pumroy · SciRah

Researcher profile · Semantic Scholar

R. Pumroy

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R. Pumroy — researcher profile on SciRah

h-index: 17
Works: 67
Citations: 1,170

Most-cited papers

Diversification of importin-α isoforms in cellular trafficking and disease states
R. Pumroy, G. Cingolani
2015Biochemical Journal208 citations Open access
Semantic Scholar
Structural insights on TRPV5 gating by endogenous modulators
T. Hughes, R. Pumroy, A. Yazici, M. Kasimova +8 more
2018Nature Communications144 citations Open access
Semantic Scholar
Molecular mechanism of TRPV2 channel modulation by cannabidiol
R. Pumroy, A. Samanta, Yu-Hang Liu, T. Hughes +7 more
2019bioRxiv138 citations Open access
Semantic Scholar
Structural insights into the gating mechanisms of TRPV Channels
R. Pumroy, E. C. Fluck, T. Ahmed, V. Moiseenkova-Bell
2020Cell Calcium79 citations Open access
Semantic Scholar
Oxidation of methionine residues activates the high-threshold heat-sensitive ion channel TRPV2
Tabea C Fricke, F. Echtermeyer, Johannes Zielke, J. de la Roche +9 more
2019Proceedings of the National Academy of Sciences of the United States of America78 citations Open access
Semantic Scholar
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression
J. Conde, R. Pumroy, Charlotte Baker, T. Rodrigues +26 more
2021ACS Central Science61 citations Open access
Semantic Scholar
Structural insights into TRPV2 activation by small molecules
R. Pumroy, Anna D. Protopopova, Tabea C Fricke, Iris Lange +8 more
2022Nature Communications60 citations Open access
Semantic Scholar
In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity
Ziyang Xu, Megan C. Wise, Neethu Chokkalingam, Susanne N. Walker +19 more
2020Advancement of science51 citations Open access
Semantic Scholar
Three-dimensional context rather than NLS amino acid sequence determines importin α subtype specificity for RCC1
R. Sankhala, R. Lokareddy, S. Begum, R. Pumroy +2 more
2017Nature Communications49 citations Open access
Semantic Scholar
Cryo-EM Structure of the Periplasmic Tunnel of T7 DNA-Ejectosome at 2.7 Å resolution
N. Swanson, R. Lokareddy, Feng-Lin Li, C.F.D. Hou +6 more
2021Molecules and Cells42 citations Open access
Semantic Scholar
Structural insights into the molecular mechanism of mouse TRPA1 activation and inhibition
A. Samanta, J. Kiselar, R. Pumroy, Seungil Han +1 more
2018The Journal of General Physiology31 citations Open access
Semantic Scholar
Nucleoporin Nup50 Stabilizes Closed Conformation of Armadillo repeat 10 in Importin α5*
R. Pumroy, Jonathan D Nardozzi, D. Hart, M. Root +1 more
2011Journal of Biological Chemistry30 citations Open access
Semantic Scholar
Molecular details of ruthenium red pore block in TRPV channels
R. Pumroy, J. J. De Jesus-Perez, Anna D. Protopopova, Julia A. Rocereta +6 more
2024EMBO Reports27 citations Open access
Semantic Scholar
General Model for Retroviral Capsid Pattern Recognition by TRIM5 Proteins
J. M. Wagner, Devin E. Christensen, A. Bhattacharya, D. Dawidziak +8 more
2017Journal of Virology26 citations Open access
Semantic Scholar
Functional and structural insights into activation of TRPV2 by weak acids
Ferdinand M. Haug, R. Pumroy, A. Sridhar, Sebastian Pantke +12 more
2024EMBO Journal25 citations Open access
Semantic Scholar
The LexA-RecA* structure reveals a cryptic lock-and-key mechanism for SOS activation
Michael B. Cory, Allen Li, Christina M. Hurley, Peter J. Carman +8 more
2024Nature Structural & Molecular Biology24 citations Open access
Semantic Scholar
Context-Specific Function of the Engineered Peptide Domain of PHP.B
R. Martino, E. C. Fluck, Jacqueline Murphy, Qiang Wang +7 more
2021Journal of Virology18 citations Open access
Semantic Scholar
Structural insights into TRPV2 modulation by probenecid
Julia A. Rocereta, Toni Sturhahn, R. Pumroy, Tabea C. Fricke +3 more
2025Nature Structural & Molecular Biology15 citations
Semantic Scholar
Intrinsically disordered regions in TRPV2 mediate protein-protein interactions
Raghavendar R. Sanganna Gari, Grigory Tagiltsev, R. Pumroy, Yi-Ning Jiang +3 more
2023Communications Biology13 citations Open access
Semantic Scholar
Calmodulin-bound full-length rbTRPV5
T. Hughes, R. Pumroy, V. Moiseenkova-Bell
20189 citations
Semantic Scholar
CryoEM structure of an MHC-I/TAPBPR peptide-bound intermediate reveals the mechanism of antigen proofreading
Yi Sun, R. Pumroy, Leena Mallik, Apala Chaudhuri +6 more
2025Proceedings of the National Academy of Sciences of the United States of America8 citations Open access
Semantic Scholar
Molecular determinants of 2-aminoethoxydiphenyl borate sensitivity of transient receptor potential vanilloid 2-unexpected differences between 2 rodent orthologs
Tabea C. Fricke, Anna Ramisch, R. Pumroy, Sebastian Pantke +6 more
2025Molecular Pharmacology7 citations Open access
Semantic Scholar
Modulation of TRPV2 by endogenous and exogenous ligands: A computational study
Shasha Feng, R. Pumroy, Anna D. Protopopova, V. Moiseenkova-Bell +1 more
2022Protein Science7 citations Open access
Semantic Scholar
TRPV2 interaction with small molecules and lipids revealed by cryo-EM
Anna D. Protopopova, R. Pumroy, J. de la Roche, Ferdinand M. Haug +5 more
20206 citations Open access
Semantic Scholar
Defining AV2‐1 as a novel pharmacological probe to target human and rodent TRPV2
Andrea Leipe, Julia A. Rocereta, R. Pumroy, Andreas Leffler +3 more
2026British Journal of Pharmacology4 citations Open access
Semantic Scholar
Genetic and pharmacological evidence for a role of the ion channel TRPV2 as a regulator of actin-dependent functional traits in rat basophilic leukemia cells.
Christine Herzog, Pia Mülke, Toni Stuhrhahn, Julia A. Rocereta +4 more
2025European Journal of Pharmacology4 citations Open access
Semantic Scholar
CryoEM structure of an MHC-I/TAPBPR peptide bound intermediate reveals the mechanism of antigen proofreading
Yi Sun, R. Pumroy, Leena Mallik, Apala Chaudhuri +6 more
2024bioRxiv2 citations Open access
Semantic Scholar
The LexA-RecA* structure reveals a lock-and-key mechanism for SOS activation
Michael B. Cory, Allen Li, Christina M. Hurley, Peter J. Carman +6 more
2023bioRxiv2 citations Open access
Semantic Scholar
Production and purification of TRPV2 and TRPV5 for structural and functional studies
E. C. Fluck, R. Pumroy, V. Moiseenkova-Bell
2021Methods in Enzymology2 citations Open access
Semantic Scholar
Jamming Up the “β-Staple”: Regulation of SIRT1 Activity by Its C-Terminal Regulatory Segment (CTR)
R. Pumroy, G. Cingolani
2013Journal of Molecular Biology2 citations Open access
Semantic Scholar
A series of cryo-EM structures resolves the mechanisms of how factor VIII binds to membranes and to factor IXa on the membrane surface
Vladimir N. Kolyadko, R. Pumroy, Vera Y. Moiseenkova-Bell, S. Krishnaswamy
2025Blood1 citations
Semantic Scholar
Author response: Molecular mechanism of TRPV2 channel modulation by cannabidiol
R. Pumroy, A. Samanta, Yu-Hang Liu, T. Hughes +5 more
20191 citations Open access
Semantic Scholar
Correction to “Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression”
J. Conde, R. Pumroy, Charlotte Baker, T. Rodrigues +26 more
2026ACS Central Science0 citations Open access
Semantic Scholar
Structural Basis for Membrane Binding by Coagulation Factors V and VIII and Their Specificity for Phosphatidylserine-Containing Membranes
Vladimir N. Kolyadko, R. Pumroy, Vera Y. Moiseenkova-Bell, S. Krishnaswamy
2026Proceedings of the National Academy of Sciences of the United States of America0 citations Open access
Semantic Scholar
Structural origins of species-specific differences in TRPV2 activation
Tabea C. Fricke, R. Pumroy, Julia A. Rocereta, J. J. De Jesus-Perez +7 more
2026Nature Communications0 citations Open access
Semantic Scholar
Structures of nucleotide-bound Redondovirus Rep protein link conformation and function
Saira Montermoso, Kushol Gupta, R. Pumroy, Vera Y. Moiseenkova-Bell +2 more
2026PLoS Pathogens0 citations Open access
Semantic Scholar
Structures of Nucleotide-Bound Redondovirus Rep Protein Link Conformation and Function
Saira Montermoso, Kushol Gupta, R. Pumroy, Vera Y. Moiseenkova-Bell +2 more
2025bioRxiv0 citations
Semantic Scholar
Structural insights into ligand modulation of TRPV2
R. Pumroy, Julia A. Rocereta, Toni Sturhahn, Andreas Leffler +1 more
2024Biophysical Journal0 citations Open access
Semantic Scholar
Structure of human TRPV2 ion channel informs differences in activation properties
Julia A. Rocereta, R. Pumroy, Tabea C. Fricke, Christine Herzog +2 more
2024Biophysical Journal0 citations Open access
Semantic Scholar
TRPV2 modulation by endogenous lipid and exogenous ligand (CBD)
Shasha Feng, R. Pumroy, Anna D. Protopopova, V. Moiseenkova-Bell +1 more
2022Biophysical Journal0 citations Open access
Semantic Scholar
Direct visualization of TRPV2 intrinsic disordered regions and interactions with cannabinoids
Raghavendar Reddy Sanganna Gari, R. Pumroy, V. Moiseenkova-Bell, Grigory Tagiltsev +1 more
2022Biophysical Journal0 citations Open access
Semantic Scholar
Gating of TRPV5 Channel Activity by Phosphorylation and Exogenous Ligands
E. C. Fluck, T. Hughes, R. Pumroy, V. Moiseenkova-Bell
20210 citations Open access
Semantic Scholar
Cryo-EM Structure of Adeno-Associated Virus Serotype 9 with Engineered Peptide Domain PHP.B (AAV9-PHP.B)
E. C. Fluck, R. Pumroy, V. Moiseenkova-Bell
20210 citations
Semantic Scholar
TRPV2 Modulation by Small Molecules and Lipids
Anna D. Protopopova, R. Pumroy, J. de la Roche, Ferdinand M. Haug +5 more
20210 citations Open access
Semantic Scholar
Structure of T7 DNA ejectosome periplasmic tunnel
N. Swanson, G. Cingolani, R. Pumroy
20210 citations
Semantic Scholar
Structural Insights on TRPV2 Gating by Exogenous Modulators
Pamela N. Gallo, Anna D. Protopopova, R. Pumroy, V. Moiseenkova-Bell
20200 citations Open access
Semantic Scholar
Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020)
Ziyang Xu, Megan C. Wise, Neethu Chokkalingam, Susanne N. Walker +19 more
2020Advancement of science0 citations Open access
Semantic Scholar
Apo full-length rat TRPV2 in nanodiscs, state 1
R. Pumroy, V. Moiseenkova-Bell
20190 citations
Semantic Scholar
Apo full-length rat TRPV2 in nanodiscs, state 2
R. Pumroy, V. Moiseenkova-Bell
20190 citations
Semantic Scholar
CBD-bound full-length rat TRPV2 in nanodiscs, state 1
R. Pumroy, V. Moiseenkova-Bell
20190 citations
Semantic Scholar

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V. Moiseenkova-Bell×27
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Vera Y. Moiseenkova-Bell×12
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Vera Y. Moiseenkova-Bell — researcher profile on SciRah
Andreas Leffler×9
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E. C. Fluck×7
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E. C. Fluck — researcher profile on SciRah

Anna D. Protopopova×7

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Julia A. Rocereta×7

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G. Cingolani×6

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Tabea C. Fricke×6

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