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E. Delpy · SciRah

Researcher profile · Semantic Scholar

E. Delpy

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E. Delpy — researcher profile on SciRah

h-index: 14
Works: 50
Citations: 703

Most-cited papers

Arenicola marina extracellular hemoglobin: a new promising blood substitute.
M. Rousselot, E. Delpy, Christophe Drieu la Rochelle, V. Lagente +6 more
2006Biotechnology Journal135 citations
Semantic Scholar
Doxorubicin induces slow ceramide accumulation and late apoptosis in cultured adult rat ventricular myocytes.
E. Delpy, S. Hatem, N. Andrieu, C. D. de Vaumas +6 more
1999Cardiovascular Research94 citations Open access
Semantic Scholar
Effects of cyclic GMP elevation on isoprenaline‐induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3
E. Delpy, H. Coste, Anne-Charlotte le Monnier Gouville
1996British Journal of Pharmacology92 citations Open access
Semantic Scholar
Early redistribution of plasma membrane phosphatidylserine during apoptosis of adult rat ventricular myocytes in vitro
Catherine Rucker-Martin, Morgana Hénaff, Stéphane N. Hatem, E. Delpy +1 more
1999Basic Research in Cardiology43 citations
Semantic Scholar
Microcirculation and NO-CO studies of a natural extracellular hemoglobin developed for an oxygen therapeutic carrier.
Amy G. Tsai, M. Intaglietta, H. Sakai, E. Delpy +3 more
2012Current Drug Discovery Technologies39 citations
Semantic Scholar
Efficacy of the natural oxygen transporter HEMO2life® in cold preservation in a preclinical porcine model of donation after cardiac death
Jacques Kaminski, P. Hannaert, Abdelsalam Kasil, R. Thuillier +6 more
2019Transplant International32 citations
Semantic Scholar
Therapeutic Potential of Hemoglobin Derived from the Marine Worm Arenicola marina (M101): A Literature Review of a Breakthrough Innovation
Fareeha Batool, E. Delpy, F. Zal, Elisabeth Leize-Zal +1 more
2021Marine Drugs30 citations Open access
Semantic Scholar
Adding the oxygen carrier M101 to a cold-storage solution could be an alternative to HOPE for liver graft preservation
Pierre Alix, D. Val-Laillet, B. Turlin, I. Ben Mosbah +7 more
2020JHEP Reports28 citations Open access
Semantic Scholar
Characterization of a hyaluronic acid-based hydrogel containing an extracellular oxygen carrier (M101) for periodontitis treatment: an in vitro study.
H. Özçelik, Fareeha Batool, Maïwenn Corre, Alexandre Garlaschelli +7 more
2021International journal of pharmaceutics26 citations Open access
Semantic Scholar
A therapeutic oxygen carrier isolated from Arenicola marina decreased P. gingivalis induced inflammation and tissue destruction
Fareeha Batool, Céline Stutz, C. Petit, N. Benkirane-Jessel +4 more
2020Scientific Reports25 citations Open access
Semantic Scholar
Beneficial effects of the novel marine oxygen carrier M101 during cold preservation of rat and human pancreas
Florent Lemaire, S. Sigrist, E. Delpy, Julien Cherfan +5 more
2019Journal of Cellular and Molecular Medicine25 citations Open access
Semantic Scholar
Social housing of non-rodents during cardiovascular recordings in safety pharmacology and toxicology studies
H. Prior, A. Bottomley, P. Champéroux, Jason S. Cordes +15 more
2016Journal of pharmacological and toxicological methods18 citations Open access
Semantic Scholar
Cardiovascular effects of a novel, potent and selective phosphodiesterase 5 inhibitor, DMPPO: in vitro and in vivo characterization
E. Delpy, Anne-Charlotte le Monnier Gouville
1996British Journal of Pharmacology17 citations Open access
Semantic Scholar
A Novel Oxygen Carrier (M101) Attenuates Ischemia-Reperfusion Injuries during Static Cold Storage in Steatotic Livers
Njikem Asong-Fontem, Arnau Panisello-Roselló, Alexandre Lopez, K. Imai +4 more
2021International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
Preventing acute kidney injury during transplantation: the application of novel oxygen carriers
R. Thuillier, E. Delpy, X. Matillon, Jacques Kaminski +10 more
2019Expert Opinion on Investigational Drugs13 citations
Semantic Scholar
HEMO2 life® improves renal function independent of cold ischemia time in kidney recipients: A comparison with a large multicenter prospective cohort study.
Y. Le Meur, E. Delpy, F. Renard, T. Hauet +6 more
2021Artificial Organs12 citations
Semantic Scholar
Results from a Joined Prospective Study to Evaluate the Sensitivity of the In Vivo Dog QT Assay in Line with the ICH E14/S7B Q&A Best Practices
A. Bétat, A. Delaunois, E. Delpy, M. Loiseau +7 more
2024Clinical pharmacology and therapy10 citations Open access
Semantic Scholar
A comprehensive review of 20 years of progress in nonclinical QT evaluation and proarrhythmic assessment
E. Delpy, A. Bétat, A. Delaunois, Christophe Drieu la Rochelle +2 more
2025Journal of Pharmacokinetics and Pharmacodynamics8 citations
Semantic Scholar
Differential Effects of Aripiprazole on Electroencephalography-Recorded Gamma-Band Auditory Steady-State Response, Spontaneous Gamma Oscillations and Behavior in a Schizophrenia Rat Model
Florian W Adraoui, Kenza Hettak, G. Viardot, Magali Alix +7 more
2024International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
A therapeutic oxygen carrier isolated from Arenicola marina decreases amanitin-induced hepatotoxicity.
B. Le Daré, P. Ferron, Nessrine Bellamri, C. Ribault +4 more
2021Toxicon7 citations Open access
Semantic Scholar
M101, a therapeutic oxygen carrier derived from Arenicola marina, decreased Porphyromonas gingivalis induced hypoxia and improved periodontal healing.
Fareeha Batool, C. Petit, Céline Stutz, H. Özçelik +6 more
2022The Journal of Periodontology5 citations
Semantic Scholar
Influence of the endothelium, nitric oxide and serotonergic receptors on coronary vasomotor responses evoked by ergonovine in conscious dogs
D. Karila-Cohen, E. Delpy, J. Dubois-Randé, L. Puybasset +3 more
1999British Journal of Pharmacology5 citations Open access
Semantic Scholar
Clozapine mitigates MK-801-induced mismatch negativity impairment in a rat electroencephalography study: relevance for schizophrenia drug development.
Florian W Adraoui, M. Violas, G. Viardot, Kenza Hettak +6 more
2025Progress in Neuro-psychopharmacology and Biological Psychiatry4 citations
Semantic Scholar
Synapse formation and spontaneous activity in rat brainstem neurons in primary culture.
R. Guinamard, E. Delpy, J. Denizot, T. Jacquin
1999Brain research. Developmental brain research4 citations
Semantic Scholar
Assessment of drug-induced cardiovascular effects by telemetry in group-housed cynomolgus monkeys
A. Bétat, kevin-Sebastien Coquelin, Fabrice Infanti, E. Delpy +1 more
20143 citations
Semantic Scholar
Evaluation of the cardiac safety of new antidepressant drugs: Predictivity of a combined in vitro and in vivo approach
S. Billiald-Desquand, S. Brunet, C. Herbelles, E. Delpy +3 more
20092 citations
Semantic Scholar
25 years of applying the 3Rs principles in safety pharmacology: success stories and future perspectives
Katayoun Derakhchan, K. Rockley, Matthias Gossmann, R. Fares +6 more
2026Frontiers in Physiology1 citations Open access
Semantic Scholar
Differential effects of cariprazine, LY379268 and donepezil on EEG oscillations and auditory steady-state response in MK-801-treated rats: relevance for schizophrenia drug development.
Florian W Adraoui, M. Violas, H. Herbel, G. Viardot +8 more
2026Neuropharmacology1 citations
Semantic Scholar
Detecting drug-induced EEG alterations with machine learning: A methodological proof-of-concept study in rats treated with MK-801.
Matthieu Basset, Paul-Emeric Saunier, G. Viardot, Philippe L'HOSTIS +3 more
2026Journal of pharmacological and toxicological methods1 citations
Semantic Scholar
JTpeak, a valuable proarrhythmic risk biomarker in telemetered dogs to differentiate pure hERG from multi-ion channel blockers
A. Bétat, E. Delpy, A. Delaunois, M. Loiseau +5 more
2026Journal of pharmacological and toxicological methods0 citations
Semantic Scholar
P31-33 JTpeak interval, a New Proarrhythmic Risk Biomarker Differentiating Pure hERG from Multi-Ion Channel Blockers: a Study Evaluating the Effects of QT-positive drugs in Telemetered Dogs
A. Delaunois, H. Gerets, A. Bétat, M. Loiseau +5 more
2026Toxicology Letters0 citations
Semantic Scholar
Corrigendum to 'Clozapine mitigates MK-801-induced mismatch negativity impairment in a rat electroencephalography study: relevance for schizophrenia drug development'.
Florian W Adraoui, M. Violas, G. Viardot, Kenza Hettak +6 more
2026Progress in Neuro-psychopharmacology and Biological Psychiatry0 citations
Semantic Scholar
Concentration-QTc analysis in anaesthetized guinea-pigs as an early translational evaluation of ventricular repolarization and proarrhythmic risk assessment
E. Delpy, A. Bétat, A. Delaunois, A. Maurin +2 more
2025Journal of pharmacological and toxicological methods0 citations
Semantic Scholar
Abstract 2512: History and summary of current practices for assessment of drug-induced QT-prolongation in oncology drug development
Louis-Guillaume Marquier, Frederique Lemaux-Duvillier, S. Le Goaller, P. l'Hostis +3 more
2025Cancer Research0 citations
Semantic Scholar
An Early Cardiovascular Derisking Strategy in Drug Discovery Using the Telemetered Guinea Pig Model
E. Delpy, M. Loiseau, A. Delaunois, J. Valentin +1 more
20170 citations
Semantic Scholar
Functional Respiratory Evaluation in the Monocrotaline-Induced Pulmonary Arterial Hypertension Model in Rat
A. Lodiot, A. Bétat, N. Couvreur, E. Delpy +3 more
20170 citations
Semantic Scholar
The tilt test in non-human primate (NHP) using manual restraint: An improved method to investigate orthostatic hypotension
A. Bétat, E. Delpy, M. Bureau, J. Veillard +1 more
20160 citations
Semantic Scholar
Assessment of sedative or stimulant effect of drugs using the thiopental-induced sleeping time test
Delphine Parachou, E. Cayre, A. Deal, Manon Sauvagnat +3 more
20150 citations
Semantic Scholar
Is the telemetered guinea pig a suitable model to detect PR interval and QRS changes
A. Delaunois, A. Bétat, A. Colomar, C. Rospo +3 more
20140 citations
Semantic Scholar
Deleterious effects of gentamicin and cisplatin on renal function in rats and early detection of drug-induced kidney injury using biomarkers
E. Delpy, M. Habault, C. le Quément, C. D. la Rochelle
20130 citations
Semantic Scholar
Refinement of the PTZ infusion seizure test in the rat by evaluation of plasma concentrations of PTZ and test compound
E. Delpy, Delphine Parachou, A. Deal, Massimo Fonsi +4 more
20130 citations
Semantic Scholar
The use of both anaesthetised and telemetered conscious guinea pigs in early safety pharmacology: A case study with sunitinib
E. Delpy, M. Garreau, Fabrice Infanti, M. Loiseau +1 more
20130 citations
Semantic Scholar
Surgical approach and experimental set-up for high quality cardiovascular signals and accurate analysis of dog telemetry studies
E. Delpy, Fabrice Infanti, M. Garreau, C. D. la Rochelle
20120 citations
Semantic Scholar
Comparison of two chronically-instrumented conscious dog models for assessment of cardiovascular function in safety pharmacology
E. Delpy, Fabrice Infanti, M. Garreau, C. D. la Rochelle
20110 citations
Semantic Scholar
Interest of telemetry in mice for early safety evaluation of new drugs
E. Delpy, M. Loiseau, C. D. la Rochelle
20110 citations
Semantic Scholar
Telemetry in the guinea-pig: A model for early safety evaluation of both haemodynamic and electrocardiographic parameters
E. Delpy, K. Rytved, Eva Dam Christoffersen, A. Lykkeberg +4 more
20100 citations
Semantic Scholar
The use of whole body plethysmography to evaluate drug-induced changes in respiratory disorders: Sleep apneas, cough and bronchospasm
E. Delpy, Fabrice Infanti, M. Loiseau, C. D. la Rochelle
20100 citations
Semantic Scholar
Analyse du développement de l’inflammation pulmonaire et de l’emphysème après administration d’élastase chez le rat
E. Delpy, A. Fautrel, M. Loiseau, C. D. la Rochelle +1 more
20080 citations
Semantic Scholar
Comparison of anaesthetised and conscious rat model for the early evaluation of myocardial contractility
E. Delpy, R. Hirel, Fabrice Infanti, C. D. la Rochelle +1 more
20080 citations
Semantic Scholar
EARLY, RAPID AND INEXPENSIVE IN VIVO EVALUATION OF POTENTIAL QTC PROLONGATION
E. Delpy, Fabrice Infanti, M. Loiseau, C. D. la Rochelle
20070 citations
Semantic Scholar

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F. Zal×13
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Florian W Adraoui×5

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