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Pei-Li Gu · SciRah

Researcher profile · Semantic Scholar

Pei-Li Gu

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Pei-Li Gu — researcher profile on SciRah

h-index: 21
Works: 33
Citations: 2,644

Most-cited papers

Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells
Jian-Cong Liang, Ma Wan, Yi Zhang, Pei-Li Gu +7 more
2008Nature Cell Biology497 citations
Semantic Scholar
WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers
Edmond M. Chan, T. Shibue, James M. McFarland, B. Gaeta +37 more
2019Nature395 citations Open access
Semantic Scholar
Orphan Nuclear Receptor LRH-1 Is Required To Maintain Oct4 Expression at the Epiblast Stage of Embryonic Development
Pei-Li Gu, B. Goodwin, A. C. Chung, Xue-Ping Xu +9 more
2005Molecular and Cellular Biology311 citations Open access
Semantic Scholar
Orphan Nuclear Receptor GCNF Is Required for the Repression of Pluripotency Genes during Retinoic Acid-Induced Embryonic Stem Cell Differentiation
Pei-Li Gu, D. Le Menuet, A. C. Chung, M. Mancini +2 more
2005Molecular and Cellular Biology200 citations Open access
Semantic Scholar
CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion
Pei-Li Gu, Jin-Na Min, Yang Wang, Chen-Hui Huang +3 more
2012EMBO Journal168 citations Open access
Semantic Scholar
SNMIB/Apollo protects leading‐strand telomeres against NHEJ‐mediated repair
Y. C. Lam, S. Akhter, Pei-Li Gu, Jing Ye +6 more
2010EMBO Journal122 citations Open access
Semantic Scholar
SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres
B. Wan, Jinhu Yin, K. Horvath, J. Sarkar +10 more
2013Cell Reports117 citations Open access
Semantic Scholar
GCNF‐dependent repression of BMP‐15 and GDF‐9 mediates gamete regulation of female fertility
Zi-Jian Lan, Pei-Li Gu, Xue-Ping Xu, K. Jackson +3 more
2003EMBO Journal112 citations Open access
Semantic Scholar
Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer
Cong Chen, Pei-Li Gu, Jian Wu, Xianyun Chen +16 more
2017Nature Communications92 citations Open access
Semantic Scholar
Functional characterization of human CTC1 mutations reveals novel mechanisms responsible for the pathogenesis of the telomere disease Coats plus
Pei-Li Gu, Sandy Chang
2013Aging Cell74 citations Open access
Semantic Scholar
Differential Recruitment of Methylated CpG Binding Domains by the Orphan Receptor GCNF Initiates the Repression and Silencing of Oct4 Expression
Pei-Li Gu, D. Le Menuet, A. C. Chung, A. Cooney
2006Molecular and Cellular Biology64 citations Open access
Semantic Scholar
Novel MicroRNA Candidates and miRNA-mRNA Pairs in Embryonic Stem (ES) Cells
Pei-Li Gu, J. Reid, Xiao-Lian Gao, C. Shaw +16 more
2008PLoS ONE57 citations Open access
Semantic Scholar
Nuclear Receptors in Regulation of Mouse ES Cell Pluripotency and Differentiation
Eimear Mullen, Pei-Li Gu, A. Cooney
2007PPAR Research56 citations Open access
Semantic Scholar
Human Pot1 OB-fold mutations unleash rampant telomere instability to initiate tumorigenesis
Pei-Li Gu, Yang Wang, K. Bisht, Ling-Chia Wu +7 more
2016Oncogene52 citations Open access
Semantic Scholar
Differential Recruitment of Methyl CpG-Binding Domain Factors and DNA Methyltransferases by the Orphan Receptor Germ Cell Nuclear Factor Initiates the Repression and Silencing of Oct4
Pei-Li Gu, Xue-Ping Xu, D. Le Menuet, A. C. Chung +1 more
2011Stem Cells50 citations Open access
Semantic Scholar
Expression of the Orphan Nuclear Receptor, Germ Cell Nuclear Factor, in Mouse Gonads and Preimplantation Embryos1
Zi-Jian Lan, Pei-Li Gu, Xue-Ping Xu, A. Cooney
2003Biology of Reproduction49 citations
Semantic Scholar
CTC1‐STN1 coordinates G‐ and C‐strand synthesis to regulate telomere length
Pei-Li Gu, Shuting Jia, Taylor Takasugi, E. Smith +3 more
2018Aging Cell45 citations Open access
Semantic Scholar
Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres
Pei-Li Gu, Shuting Jia, Taylor Takasugi, V. M. Tesmer +3 more
2021Nature Communications36 citations Open access
Semantic Scholar
Evolutionary Trace-based Peptides Identify a Novel Asymmetric Interaction That Mediates Oligomerization in Nuclear Receptors*
Pei-Li Gu, Daniel H. Morgan, M. Sattar, Xue-Ping Xu +4 more
2005Journal of Biological Chemistry34 citations Open access
Semantic Scholar
Single strand DNA binding proteins 1 and 2 protect newly replicated telomeres
Pei-Li Gu, W. Deng, M. Lei, Sandy Chang
2013Cell Research33 citations Open access
Semantic Scholar
Correlated evolutionary pressure at interacting transcription factors and DNA response elements can guide the rational engineering of DNA binding specificity.
M. Raviscioni, Pei-Li Gu, M. Sattar, A. Cooney +1 more
2005Journal of Molecular Biology29 citations
Semantic Scholar
The Replisome Mediates A-NHEJ Repair of Telomeres Lacking POT1-TPP1 Independently of MRN Function
Rekha Rai, Pei-Li Gu, Cayla Broton, Chandan Kumar-Sinha +2 more
2019Cell Reports18 citations Open access
Semantic Scholar
Orphan Nuclear Receptor GCNF Is Required for the Repression ofPluripotency Genes during Retinoic Acid-Induced EmbryonicStem Cell Differentiation
Pei-Li Gu, D. Le Menuet, A. C. Chung, M. Mancini +2 more
2005Molecular and Cellular Biology13 citations Open access
Semantic Scholar
Pot1b −/− tumors activate G-quadruplex-induced DNA damage to promote telomere hyper-elongation
Taylor Takasugi, Pei-Li Gu, Fengshan Liang, Isabelle Staco +1 more
2023Nucleic Acids Research10 citations Open access
Semantic Scholar
miRNA Regulatory Circuits in ES Cells Differentiation: A Chemical Kinetics Modeling Approach
Zijun Luo, Xu-Ping Xu, Pei-Li Gu, D. Lonard +3 more
2011PLoS ONE8 citations Open access
Semantic Scholar
Polymorphisms of B-lymphocyte-associated genes CD20 and FCRL5 are associated with susceptibility to autoimmune thyroid diseases.
Yuqing Wu, Tian-Tian Cai, Wen-Yu Xu, Xiao-Rong Yang +2 more
2024Human Immunology1 citations
Semantic Scholar
Evolutionary trace-based peptides identify a novel asymmetric interaction that mediates oligomerization in nuclear receptors.
Pei-Li Gu, Daniel H. Morgan, M. Sattar, Xue-Ping Xu +4 more
2010Journal of Biological Chemistry1 citations Open access
Semantic Scholar
Abstract A033: Histone methyltransferase PRMT5 promotes melanoma immune evasion by repressing TH1-related gene networks and endogenous retroelements
S. Milette, Simon F Roy, M. Oh, Eileen Han +10 more
2026Cancer immunology research0 citations
Semantic Scholar
Targeting DNMT1 augments anti-tumor CD8⁺ T cell function
M. Deshmukh, Danielle K. Sohai, Kamal Obbad, Koonam Park +11 more
2026bioRxiv0 citations Open access
Semantic Scholar
circANKRD12/circTIMMDC1 synergistically regulates enteric neural crest cell migration via miR-181b-5p-PROX1-NOTCH1 axis in Hirschsprung’s disease
Runxi Fu, Chen Wang, Ze Xu, Jinyang Zhai +7 more
2025Pediatric Research0 citations
Semantic Scholar
2型糖尿病、骨质疏松症、2型糖尿病并发骨质疏松症患者血清胰岛素样生长因子-1的检测及意义
Yan-Rong Kang, Pei-Li Gu
20160 citations
Semantic Scholar
ORPHAN NUCLEAR RECEPTOR GCNF RECRUITS DNA METHYLTRANSFERASE DNMT3A TO OCT4 PROMOTER TO SILENCE OCT4 EXPRESSION IN DIFFERENTIATED MOUSE ES CELL
Pei-Li Gu, A. Cooney
20070 citations
Semantic Scholar
Repression of Oct4 expression by the orphan nuclear receptor GCNF requires recruitment of MBD3 to the promoter
A. Cooney, Pei-Li Gu
20060 citations
Semantic Scholar

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