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N. Lycke · SciRah

Researcher profile · Semantic Scholar

N. Lycke

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N. Lycke — researcher profile on SciRah

h-index: 52
Works: 197
Citations: 8,849

Most-cited papers

Recent progress in mucosal vaccine development: potential and limitations
N. Lycke
2012Nature reviews. Immunology804 citations
Semantic Scholar
The regulation of gut mucosal IgA B-cell responses: recent developments
N. Lycke, M. Bemark
2017Mucosal Immunology187 citations Open access
Semantic Scholar
CTA1-M2e-DD: a novel mucosal adjuvant targeted influenza vaccine.
Dubravka Grdic Eliasson, K. El Bakkouri, Karin Schön, Anna Ramne +5 more
2008Vaccine143 citations
Semantic Scholar
The universal influenza vaccine M2e-HBc administered intranasally in combination with the adjuvant CTA1-DD provides complete protection.
M. de Filette, Anna Ramne, A. Birkett, N. Lycke +4 more
2006Vaccine135 citations
Semantic Scholar
T Cell-Independent IgA Class Switch Recombination Is Restricted to the GALT and Occurs Prior to Manifest Germinal Center Formation
P. Bergqvist, Anneli Stensson, N. Lycke, M. Bemark
2010Journal of Immunology133 citations Open access
Semantic Scholar
Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells
Nimitha R. Mathew, Jayalal K. Jayanthan, I. Smirnov, Jonathan L. Robinson +16 more
2021Cell Reports120 citations Open access
Semantic Scholar
Mucosal Vaccine Development Based on Liposome Technology
Valentina Bernasconi, K. Norling, M. Bally, F. Höök +1 more
2016Journal of Immunological Research100 citations Open access
Semantic Scholar
Re-utilization of germinal centers in multiple Peyer's patches results in highly synchronized, oligoclonal, and affinity-matured gut IgA responses
P. Bergqvist, Anneli Stensson, L. Hazanov, A. Holmberg +4 more
2012Mucosal Immunology95 citations Open access
Semantic Scholar
M2e-tetramer-specific memory CD4 T cells are broadly protective against influenza infection
Dubravka Grdic Eliasson, A. Omokanye, Karin Schön, U. A. Wenzel +9 more
2017Mucosal Immunology93 citations Open access
Semantic Scholar
Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin
Liang Ye, D. Schnepf, Jan Becker, Karolina Ebert +6 more
2019Nature Immunology86 citations
Semantic Scholar
Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization
M. Bemark, Helena Hazanov, Anneli Strömberg, R. Komban +6 more
2016Nature Communications81 citations Open access
Semantic Scholar
Activated Peyer′s patch B cells sample antigen directly from M cells in the subepithelial dome
R. Komban, Anneli Strömberg, Adi Biram, J. Cervin +6 more
2019Nature Communications76 citations Open access
Semantic Scholar
The Female Lower Genital Tract Is a Privileged Compartment with IL-10 Producing Dendritic Cells and Poor Th1 Immunity following Chlamydia trachomatis Infection
E. Marks, Miguel A. Tam, N. Lycke
2010PLoS Pathogens68 citations Open access
Semantic Scholar
A Unique Role of the Cholera Toxin A1-DD Adjuvant for Long-Term Plasma and Memory B Cell Development
M. Bemark, P. Bergqvist, Anneli Stensson, A. Holmberg +2 more
2011Journal of Immunology63 citations Open access
Semantic Scholar
Cutting Edge: Retinoic Acid Signaling in B Cells Is Essential for Oral Immunization and Microflora Composition
Eirini Pantazi, E. Marks, É. Stolarczyk, N. Lycke +2 more
2015Journal of Immunology58 citations Open access
Semantic Scholar
ADP‐ribosylating enterotoxins as vaccine adjuvants
N. Lycke, Cristina Lebrero-Fernández
2018Current opinion in pharmacology (Print)56 citations
Semantic Scholar
A novel non-toxic combined CTA1-DD and ISCOMS adjuvant vector for effective mucosal immunization against influenza virus.
Dubravka Grdic Eliasson, Anja Helgeby, Karin Schön, Carolyn Nygren +6 more
2011Vaccine53 citations
Semantic Scholar
Antibiotic‐Killed Staphylococcus aureus Induces Destructive Arthritis in Mice
Abukar Ali, Xuefeng Zhu, J. Kwiecinski, I. Gjertsson +7 more
2015Arthritis & Rheumatology50 citations
Semantic Scholar
CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization.
C. Sundling, Karin Schön, A. Mörner, M. Forsell +4 more
2008Journal of General Virology50 citations Open access
Semantic Scholar
Intrarectal immunization of mice with VP6 and either LT(R192G) or CTA1-DD as adjuvant protects against fecal rotavirus shedding after EDIM challenge.
M. McNeal, M. Basu, J. Bean, J. Clements +5 more
2007Vaccine50 citations
Semantic Scholar
Mucosal immunization of piglets with purified F18 fimbriae does not protect against F18+ Escherichia coli infection.
F. Verdonck, P. Tiels, K. van Gog, B. Goddeeris +3 more
2007Veterinary Immunology and Immunopathology47 citations Open access
Semantic Scholar
Differential CD28 and Inducible Costimulatory Molecule Signaling Requirements for Protective CD4+ T-Cell-Mediated Immunity against Genital Tract Chlamydia trachomatis Infection
E. Marks, M. Verolin, Anneli Stensson, N. Lycke
2007Infection and Immunity47 citations Open access
Semantic Scholar
Immunity against a Chlamydia infection and disease may be determined by a balance of IL‐17 signaling
Connor P. O'Meara, Charles W. Armitage, Marina C. G. Harvie, D. Andrew +3 more
2014Immunology and Cell Biology45 citations Open access
Semantic Scholar
Complement Activation and Complement Receptors on Follicular Dendritic Cells Are Critical for the Function of a Targeted Adjuvant
J. Mattsson, U. Yrlid, Anneli Stensson, Karin Schön +3 more
2011Journal of Immunology45 citations Open access
Semantic Scholar
Immunization with a MOMP-Based Vaccine Protects Mice against a Pulmonary Chlamydia Challenge and Identifies a Disconnection between Infection and Pathology
Connor P. O'Meara, Charles W. Armitage, Marina C. G. Harvie, P. Timms +2 more
2013PLoS ONE42 citations Open access
Semantic Scholar
CTA1-DD is an effective adjuvant for targeting anti-chlamydial immunity to the murine genital mucosa.
Kelly A. Cunningham, A. Carey, N. Lycke, P. Timms +1 more
2009Journal of Reproductive Immunology40 citations
Semantic Scholar
Type I and Type III Interferons Differ in Their Adjuvant Activities for Influenza Vaccines
Liang Ye, Annette Ohnemus, Ching-Ong Li, H. Gad +3 more
2019Journal of Virology38 citations Open access
Semantic Scholar
Clonotypic analysis of protective influenza M2e-specific lung resident Th17 memory cells reveals extensive functional diversity
A. Omokanye, Ching-Ong Li, Cristina Lebrero-Fernández, Valentina Bernasconi +6 more
2022Mucosal Immunology31 citations Open access
Semantic Scholar
A vaccine combination of lipid nanoparticles and a cholera toxin adjuvant derivative greatly improves lung protection against influenza virus infection
Valentina Bernasconi, K. Norling, I. Gribonika, Ching-Ong Li +8 more
2020Mucosal Immunology30 citations Open access
Semantic Scholar
Porous Nanoparticles With Self-Adjuvanting M2e-Fusion Protein and Recombinant Hemagglutinin Provide Strong and Broadly Protective Immunity Against Influenza Virus Infections
Valentina Bernasconi, B. Bernocchi, Liang Ye, M. Lê +7 more
2018Frontiers in Immunology30 citations Open access
Semantic Scholar
Mast Cells Contribute to the Mucosal Adjuvant Effect of CTA1–DD after IgG-Complex Formation
Yuni Fang, L. Larsson, J. Mattsson, N. Lycke +1 more
2010Journal of Immunology29 citations Open access
Semantic Scholar
Role of CTA1R7K-COL-DD as a novel therapeutic mucosal tolerance-inducing vector for treatment of collagen-induced arthritis.
Annemarie Hasselberg, Karin Schön, A. Tarkowski, N. Lycke
2009Arthritis & Rheumatism27 citations
Semantic Scholar
The CTA1-DD adjuvant strongly potentiates follicular dendritic cell function and germinal center formation, which results in improved neonatal immunization
Sophie Schussek, Valentina Bernasconi, J. Mattsson, U. A. Wenzel +4 more
2020Mucosal Immunology24 citations Open access
Semantic Scholar
Subcomponent Vaccine Based on CTA1-DD Adjuvant with Incorporated UreB Class II Peptides Stimulates Protective Helicobacter pylori Immunity
J. Nedrud, Nayer Bagheri, Karin Schön, W. Xin +3 more
2013PLoS ONE24 citations Open access
Semantic Scholar
Class-switch recombination to IgA in the Peyer’s patches requires natural thymus-derived Tregs and appears to be antigen independent
I. Gribonika, Dubravka Grdic Eliasson, Rakesh K. Chandode, Karin Schön +3 more
2019Mucosal Immunology23 citations Open access
Semantic Scholar
Peyer’s patch TH17 cells are dispensable for gut IgA responses to oral immunization
I. Gribonika, Anneli Strömberg, Cristina Lebrero-Fernández, Karin Schön +3 more
2022Science immunology22 citations
Semantic Scholar
Targeting Mycobacterium tuberculosis Antigens to Dendritic Cells via the DC-Specific-ICAM3-Grabbing-Nonintegrin Receptor Induces Strong T-Helper 1 Immune Responses
L. Velasquez, Philipp Stüve, M. Gentilini, M. Swallow +9 more
2018Frontiers in Immunology22 citations Open access
Semantic Scholar
Cross-Protective Potential and Protection-Relevant Immune Mechanisms of Whole Inactivated Influenza Virus Vaccines Are Determined by Adjuvants and Route of Immunization
Y. Bhide, W. Dong, I. Gribonika, Daniëlle Voshart +10 more
2019Frontiers in Immunology19 citations Open access
Semantic Scholar
Mechanisms of Adjuvant Action
N. Lycke
200619 citations
Semantic Scholar
Feeding transgenic plants that express a tolerogenic fusion protein effectively protects against arthritis.
Charlotta Hansson, Karin Schön, Irina Kalbina, Å. Strid +3 more
2016Plant Biotechnology Journal17 citations Open access
Semantic Scholar
ADP-ribosylating adjuvant reveals plasticity in cDC1 cells that drive mucosal Th17 cell development and protection against influenza virus infection
M. Arabpour, Cristina Lebrero-Fernández, Karin Schön, Anneli Strömberg +7 more
2022Mucosal Immunology16 citations Open access
Semantic Scholar
Multistage vaccines containing outer membrane, type III secretion system and inclusion membrane proteins protects against a Chlamydia genital tract infection and pathology.
Connor P. O'Meara, Charles W. Armitage, D. Andrew, Avinash Kollipara +5 more
2017Vaccine15 citations Open access
Semantic Scholar
The role of Peyer’s patches in synchronizing gut IgA responses
N. Lycke, M. Bemark
2012Front. Immun.14 citations Open access
Semantic Scholar
Histo-blood group antigens of glycosphingolipids predict susceptibility of human intestinal enteroids to norovirus infection
I. Rimkutė, Konrad Thorsteinsson, Marcus Henricsson, Victoria R. Tenge +9 more
2020Journal of Biological Chemistry13 citations Open access
Semantic Scholar
Gel phase DSPC-based liposomes are superior to fluid phase liposomes at augmenting antigen presentation on MHC II and display of co-stimulatory molecules by dendritic cells in vitro.
K. Norling, Valentina Bernasconi, Víctor Agmo Hernández, Nagma Parveen +4 more
2019ACS Infectious Diseases13 citations
Semantic Scholar
ADP-Ribosylation Controls the Outcome of Tolerance or Enhanced Priming Following Mucosal Immunization
Annemarie Hasselberg, L. Ekman, L. Yrlid, Karin Schön +1 more
2010Journal of Immunology13 citations Open access
Semantic Scholar
The extracellular matrix of lymph node reticular fibers modulates follicle border interactions and germinal center formation
Jian Song, Tushar Deshpande, Xueli Zhang, Melanie-Jane Hannocks +3 more
2023iScience11 citations Open access
Semantic Scholar
Prevention of influenza virus infection and transmission by intranasal administration of a porous maltodextrin nanoparticle-formulated vaccine.
Minh Quan Le, Liang Ye, Valentina Bernasconi, R. Carpentier +4 more
2020International journal of pharmaceutics11 citations Open access
Semantic Scholar
Vaccination with Helicobacter pylori attachment proteins protects against gastric cancer
Jeanna A. Bugaytsova, A. Piddubnyi, I. Tkachenko, L. Rakhimova +14 more
2023bioRxiv10 citations Open access
Semantic Scholar
A Novel Approach to Reinstating Tolerance in Experimental Autoimmune Myasthenia Gravis Using a Targeted Fusion Protein, mCTA1–T146
A. Consonni, Sapna Sharma, Karin Schön, Cristina Lebrero-Fernández +3 more
2017Frontiers in Immunology10 citations Open access
Semantic Scholar

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