Lauren A Seiple

Most-cited papers

1. Linking uracil base excision repair and 5-fluorouracil toxicity in yeast

   Lauren A Seiple, P. Jaruga, M. Dizdaroglu, J. Stivers

   2006Nucleic Acids Research108 citations Open access

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2. Potent Inhibition of Human Apurinic/Apyrimidinic Endonuclease 1 by Arylstibonic Acids

   Lauren A Seiple, J. Cardellina, R. Akee, J. Stivers

   2008Molecular Pharmacology80 citations Open access

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3. Uracil-directed ligand tethering: an efficient strategy for uracil DNA glycosylase (UNG) inhibitor development.

   Yu-Lin Jiang, D. Krosky, Lauren A Seiple, J. Stivers

   2005Journal of the American Chemical Society67 citations Open access

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4. Electrostatic guidance of glycosyl cation migration along the reaction coordinate of uracil DNA glycosylase.

   M. Bianchet, Lauren A Seiple, Yu-Lin Jiang, Y. Ichikawa +2 more

   2003Biochemistry54 citations

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5. Mimicking damaged DNA with a small molecule inhibitor of human UNG2

   Daniel J. Krosky, M. Bianchet, Lauren A Seiple, Suhman Chung +2 more

   2006Nucleic Acids Research38 citations Open access

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6. POTENT INHIBITION OF HUMAN AP ENDONUCLEASE 1 BY ARYLSTIBONIC ACIDS

   Lauren A Seiple, J. Cardellina, R. Akee, J. Stivers

   20073 citations

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7. Uracil base excision repair as a therapeutic target

   Lauren A Seiple

   20080 citations

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8. Uracil DNA glycosylase bound to a cationic 1-aza-2'-deoxyribose-containing DNA

   M. Bianchet, Lauren A Seiple, Yu-Ling Jiang, Y. Ichikawa +2 more

   20040 citations

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