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Lauren M. Zasadil · SciRah

Researcher profile · Semantic Scholar

Lauren M. Zasadil

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Lauren M. Zasadil — researcher profile on SciRah

h-index: 16
Works: 24
Citations: 1,885

Most-cited papers

Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles
Lauren M. Zasadil, Kristen A. Andersen, D. Yeum, G. Rocque +5 more
2014Science Translational Medicine390 citations Open access
Semantic Scholar
Chromosome mis-segregation generates cell cycle-arrested cells with complex karyotypes that are eliminated by the immune system
S. Santaguida, Amelia Richardson, D. Iyer, O. M'Saad +6 more
2017Developmental Cell338 citations Open access
Semantic Scholar
Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors
Alain D. Silk, Lauren M. Zasadil, A. Holland, B. Vitre +2 more
2013Proceedings of the National Academy of Sciences of the United States of America255 citations Open access
Semantic Scholar
Living in CIN: mitotic infidelity and its consequences for tumor promotion and suppression
L. Funk, Lauren M. Zasadil, Beth A. Weaver
2016Developmental Cell135 citations Open access
Semantic Scholar
Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer
R. Denu, Lauren M. Zasadil, Craig Kanugh, J. Laffin +2 more
2016BMC Cancer116 citations Open access
Semantic Scholar
Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons
Sean D. Ryan, E. Britigan, Lauren M. Zasadil, Kristen Witte +3 more
2012Proceedings of the National Academy of Sciences of the United States of America110 citations Open access
Semantic Scholar
Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel
Christina M. Scribano, Jun Wan, Karla Esbona, John B. Tucker +17 more
2021Science Translational Medicine106 citations Open access
Semantic Scholar
2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells
Lauren M. Zasadil, E. Britigan, Beth A. Weaver
2013Seminars in Cell and Developmental Biology100 citations Open access
Semantic Scholar
The role of microtubules in neutrophil polarity and migration in live zebrafish
S. Yoo, Pui-Ying Lam, Mark R. Eichelberg, Lauren M. Zasadil +2 more
2012Journal of Cell Science73 citations Open access
Semantic Scholar
Clonal selection of stable aneuploidies in progenitor cells drives high-prevalence tumorigenesis
M. Trakala, Muskaan Aggarwal, Courtney Sniffen, Lauren M. Zasadil +13 more
2021Genes & Development60 citations Open access
Semantic Scholar
High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation
Lauren M. Zasadil, E. Britigan, Sean D. Ryan, C. Kaur +4 more
2016Molecular Biology of the Cell60 citations Open access
Semantic Scholar
Specific isoforms of Drosophila Shroom define spatial requirements for the induction of apical constriction
C. Bolinger, Lauren M. Zasadil, Ryan Rizaldy, Jeffrey D. Hildebrand
2010Developmental Dynamics35 citations Open access
Semantic Scholar
High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability
D. Matson, R. Denu, Lauren M. Zasadil, M. Burkard +3 more
2021BMC Cancer31 citations Open access
Semantic Scholar
Identification of selective lead compounds for treatment of high-ploidy breast cancer
A. Choudhary, Brittany Zachek, Robert F. Lera, Lauren M. Zasadil +10 more
2015Molecular Cancer Therapeutics25 citations Open access
Semantic Scholar
The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B
E. Britigan, Jun Wan, Lauren M. Zasadil, Sean D. Ryan +1 more
2014Molecular Biology of the Cell25 citations Open access
Semantic Scholar
A Golgi localized pool of the mitotic checkpoint component Mad1 controls integrin secretion and cell migration
Jun Wan, F. Zhu, Lauren M. Zasadil, Jia-Quan Yu +6 more
2014Current Biology24 citations Open access
Semantic Scholar
Supplementary Materials for Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles
Lauren M. Zasadil, Kristen A. Andersen, D. Yeum, G. Rocque +5 more
20143 citations
Semantic Scholar
Abstract 3064: An alternative mechanism of action for paclitaxel in breast cancer
Lauren M. Zasadil, Beth A. Weaver
20122 citations
Semantic Scholar
Abstract 2526: Polyploidy: A new breast cancer subtype and a lead compound that targets it with high selectivity
M. Burkard, A. Choudhary, Robert F. Lera, Ross Fedenia +5 more
20141 citations
Semantic Scholar
Abstract P3-07-53: Chromosomal instability as a predictor of sensitivity to paclitaxel
Ll Cavalcante, R. Denu, Lauren M. Zasadil, Beth A. Weaver +1 more
20160 citations
Semantic Scholar
Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer
R. Denu, Lauren M. Zasadil, Craig Kanugh, J. Laffin +2 more
2016BMC Cancer0 citations Open access
Semantic Scholar
Report e Mitotic Checkpoint Component Mad 1 Controls Integrin Secretion and Cell Migration
Jun Wan, F. Zhu, Lauren M. Zasadil, Jia-Quan Yu +6 more
20140 citations
Semantic Scholar
Abstract 1750: Clinically relevant paclitaxel concentrations cause chromosome missegregation rather than mitotic arrest.
Lauren M. Zasadil, M. Burkard, Beth A. Weaver
20130 citations
Semantic Scholar
The Characterization of Drosophila Shroom
Lauren M. Zasadil
20100 citations
Semantic Scholar

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Beth A. Weaver×19
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Beth A. Weaver — researcher profile on SciRah
M. Burkard×10
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R. Denu×5
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