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K. Clinch · SciRah

Researcher profile · Semantic Scholar

K. Clinch

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K. Clinch — researcher profile on SciRah

h-index: 20
Works: 52
Citations: 1,062

Most-cited papers

Femtomolar Transition State Analogue Inhibitors of 5′-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase from Escherichia coli*
Vipender Singh, G. B. Evans, Dirk H. Lenz, J. M. Mason +8 more
2005Journal of Biological Chemistry128 citations Open access
Semantic Scholar
A Novel Mechanism for Desulfation of Mucin: Identification and Cloning of a Mucin-Desulfating Glycosidase (Sulfoglycosidase) from Prevotella Strain RS2
Jung-Hyun Rho, D. P. Wright, D. Christie, K. Clinch +2 more
2005Journal of Bacteriology80 citations Open access
Semantic Scholar
Third-Generation Immucillins: Syntheses and Bio-Activities of Acyclic Immucillin Inhibitors of Human Purine Nucleoside Phosphorylase
K. Clinch, G. B. Evans, Richard F. G. Fröhlich, R. Furneaux +7 more
2009Journal of Medicinal Chemistry67 citations Open access
Semantic Scholar
Acyclic Immucillin Phosphonates: Second generation inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase
K. Hazleton, M. Ho, M. Cassera, K. Clinch +6 more
2012Chemistry and Biology63 citations Open access
Semantic Scholar
Syntheses and bio-activities of the L-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases.
K. Clinch, G. B. Evans, G. Fleet, R. Furneaux +7 more
2006Organic and biomolecular chemistry59 citations
Semantic Scholar
Four generations of transition-state analogues for human purine nucleoside phosphorylase
M. Ho, Wuxian Shi, A. Rinaldo-Matthis, P. Tyler +4 more
2010Proceedings of the National Academy of Sciences of the United States of America58 citations Open access
Semantic Scholar
Altered Enthalpy-Entropy Compensation in Picomolar Transition State Analogues of Human Purine Nucleoside Phosphorylase
A. Edwards, J. M. Mason, K. Clinch, P. Tyler +2 more
2009Biochemistry54 citations Open access
Semantic Scholar
New Antibiotic Candidates against Helicobacter pylori
Shan-Zhi Wang, S. A. Cameron, K. Clinch, G. B. Evans +3 more
2015Journal of the American Chemical Society38 citations Open access
Semantic Scholar
Acyclic ribooxacarbenium ion mimics as transition state analogues of human and malarial purine nucleoside phosphorylases.
E. A. Taylor, K. Clinch, Peter M. Kelly, Lei Li +3 more
2007Journal of the American Chemical Society38 citations
Semantic Scholar
Acyclic phosph(on)ate inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase
K. Clinch, D. Crump, G. B. Evans, K. Hazleton +3 more
2013Bioorganic & Medicinal Chemistry34 citations Open access
Semantic Scholar
Combined Infection Control and Enhanced Osteogenic Differentiation Capacity on Additive Manufactured Ti‐6Al‐4V are Mediated via Titania Nanotube Delivery of Novel Biofilm Inhibitors
Jun Li, I. Mutreja, G. Hooper, K. Clinch +3 more
2020Advanced Materials Interfaces31 citations
Semantic Scholar
Structural transformations in the dynamics of Michaelis complex formation in lactate dehydrogenase.
Sebastian McClendon, D. Vu, K. Clinch, R. Callender +1 more
2005Biophysical Journal29 citations Open access
Semantic Scholar
Synthesis of cyclic pyranopterin monophosphate, a biosynthetic intermediate in the molybdenum cofactor pathway.
K. Clinch, D. Watt, R. Dixon, S. Baars +7 more
2013Journal of Medicinal Chemistry28 citations
Semantic Scholar
On the pathway of forming enzymatically productive ligand-protein complexes in lactate dehydrogenase.
H. Deng, S. Brewer, D. Vu, K. Clinch +2 more
2008Biophysical Journal28 citations Open access
Semantic Scholar
Conformational heterogeneity within the Michaelis complex of lactate dehydrogenase
H. Deng, D. V. Vu, K. Clinch, R. Desamero +2 more
2011Journal of Physical Chemistry B27 citations Open access
Semantic Scholar
Transition State Analogues of Plasmodium falciparum and Human Orotate Phosphoribosyltransferases*
Yong Zhang, G. B. Evans, K. Clinch, D. Crump +6 more
2013Journal of Biological Chemistry24 citations Open access
Semantic Scholar
Synthesis of (2R,4S,5S)-5-acetamido-4-hydroxy-pipecolinic acid as a potential inhibitor of sialidases
K. Clinch, A. Vasella, R. Schauer
198724 citations
Semantic Scholar
L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase.
A. Rinaldo-Matthis, A. S. Murkin, U. Ramagopal, K. Clinch +6 more
2008Journal of the American Chemical Society22 citations Open access
Semantic Scholar
Synthesis and utility of sulfated chromogenic carbohydrate model substrates for measuring activities of mucin-desulfating enzymes.
K. Clinch, G. B. Evans, R. Furneaux, P. M. Rendle +5 more
2002Carbohydrate Research21 citations
Semantic Scholar
Immucillins ImmA and ImmH Are Effective and Non-toxic in the Treatment of Experimental Visceral Leishmaniasis
E. O. Freitas, D. Nico, Marcus Vinícius Alves-Silva, A. Morrot +5 more
2015PLoS Neglected Tropical Diseases20 citations Open access
Semantic Scholar
A novel and simple colorimetric method for screening Giardia intestinalis and anti-giardial activity in vitro
E. W. Kang, K. Clinch, R. Furneaux, J. E. Harvey +2 more
1998Parasitology19 citations
Semantic Scholar
Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics
K. Clinch, G. B. Evans, Richard F. G. Fröhlich, Shivali A. Gulab +5 more
2012Bioorganic & Medicinal Chemistry16 citations Open access
Semantic Scholar
A practical synthesis of (3R,4R)-N-tert-butoxycarbonyl-4-hydroxymethylpyrrolidin-3-ol.
K. Clinch, G. B. Evans, R. Furneaux, Dirk H. Lenz +4 more
2007Organic and biomolecular chemistry16 citations
Semantic Scholar
Synthesis of substituted tetrahydropyridines and M-hydroxybenzoic acids
K. Clinch, C. Marquez, M. J. Parrott, R. Ramage
198916 citations
Semantic Scholar
A route to spiroketals using radical translocation
Chris Brown, N. Simpkins, K. Clinch
199315 citations
Semantic Scholar
Immucillins Impair Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis Multiplication In Vitro
E. O. Freitas, D. Nico, Rong-Bin Guan, J. Meyer-Fernandes +5 more
2015PLoS ONE13 citations Open access
Semantic Scholar
Immucillins in Custom Catalytic-Site Cavities
A. S. Murkin, K. Clinch, J. M. Mason, P. Tyler +1 more
2008Bioorganic & Medicinal Chemistry Letters13 citations Open access
Semantic Scholar
Biofilm Inhibition via Delivery of Novel Methylthioadenosine Nucleosidase Inhibitors from PVA-Tyramine Hydrogels while Supporting Mesenchymal Stromal Cell Viability.
I. Mutreja, Suzanne L. Warring, K. Lim, Tara Swadi +10 more
2018ACS Biomaterials Science & Engineering12 citations Open access
Semantic Scholar
Kinetic Characterization and Inhibition of Trypanosoma cruzi Hypoxanthine–Guanine Phosphoribosyltransferases
Kayla Glockzin, Demetrios H Kostomiris, Yacoba V. T. Minnow, Kajitha Suthagar +7 more
2022Biochemistry11 citations Open access
Semantic Scholar
Reducing the Toxicity of Designer Aminoglycosides as Nonsense Mutation Readthrough Agents for Therapeutic Targets.
Michael Popadynec, Alireza Baradaran-Heravi, Benjamin Alford, S. A. Cameron +11 more
2021ACS Medicinal Chemistry Letters9 citations Open access
Semantic Scholar
Trichomonas vaginalis: detection of nucleoside hydrolase activity as a potential screening procedure.
A. M. Gero, E. W. Kang, J. E. Harvey, Philip J. Schofield +2 more
2000Experimental parasitology9 citations
Semantic Scholar
An Isomer of Galidesivir That Potently Inhibits Influenza Viruses and Members of the Bunyavirales Order.
K. Sparrow, Rinu Shrestha, James M. Wood, K. Clinch +9 more
2023ACS Medicinal Chemistry Letters8 citations Open access
Semantic Scholar
Syntheses of 5-Chlorouracils/Thymines with 1-[Phosphono(Methyl/Difluoromethyl)]-1,2-Unsaturated-Moiety-Substituted Methyl Groups at N(1) and Human Thymidine Phosphorylase Inhibitory Activity
Matthew R. Birck, K. Clinch, G. Gainsford, V. Schramm +1 more
20098 citations
Semantic Scholar
Inhibition and Mechanism of Plasmodium falciparum Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferase
Yacoba V. T. Minnow, Kajitha Suthagar, K. Clinch, R. Ducati +6 more
2022ACS Chemical Biology7 citations Open access
Semantic Scholar
Stobadine protects ion pump ATPases from free radical inhibition.
K. Clinch, F. Vincenzi, T. Rohn, T. Hinds
1993Proceedings of the Western Pharmacology Society5 citations
Semantic Scholar
Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors
Kayla Glockzin, K. Meneely, Ryan Hughes, Sean W. Maatouk +8 more
2023Biochemistry3 citations Open access
Semantic Scholar
Synthesis of analogues of monic acids A and C: Potential herbicides and inhibitors of isoleucyl tRNA synthetase
K. Clinch
19963 citations
Semantic Scholar
tert-Butyl (2R,4aR,5aR,11aS,12R,12aR)-8-[bis(tert-butoxycarbonyl)amino]-12-hydroxy-2-methoxy-2,10-dioxo-4,4a,5a,6,9,10,11,11a,12,12a-decahydro-2H-1,3,5-trioxa-6,7,9,11-tetraaza-2λ5-phosphatetracene-6-carboxylate methanol monosolvate monohydrate
G. Gainsford, K. Clinch, R. Dixon, A. Tiwari
2012Acta Crystallographica Section E2 citations Open access
Semantic Scholar
Syntheses of the 4-nitrophenyl glycosides of hyalobiuronic acid and chondrosine.
D. Watt, K. Clinch, G. Slim
2002Carbohydrate Research2 citations
Semantic Scholar
(4R,5S)-4-Hydroxymethyl-5-[(methylsulfanyl)methyl]-1,3-oxazolidin-2-one
G. Gainsford, K. Clinch
2012Acta Crystallographica Section E1 citations Open access
Semantic Scholar
3-Benzoyl-5-chlorouracil
G. Gainsford, K. Clinch
2009Acta Crystallographica Section E1 citations Open access
Semantic Scholar
Carbohydrate Chemistry. Monosaccharides, Disaccharides, and Specific Oligosaccharides. Volume 25. A Review of the Recent Literature Published During 1991.
R. Ferrier, R. Blattner, K. Clinch, R. Furneaux +3 more
19941 citations
Semantic Scholar
Synthesis of (2R,4S,5S)-5-Acetamido-4-hydroxypipecolinic Acid (II) as a Potential Inhibitor of Sialidases.
K. Clinch, A. Vasella, R. Schauer
19881 citations
Semantic Scholar
Acrylic amininhibotorer of nukleosidphosphorylaser and hydrolases
Shivali A. Gulab, K. Clinch, G. B. Evans, R. Furneaux +4 more
20070 citations
Semantic Scholar
I improved method for the preparation of compounds 3-hyd.
K. Clinch, G. B. Evans, Dirk H. Lenz, J. M. Mason +1 more
20050 citations
Semantic Scholar
Corrigendum to “Synthesis and utility of sulfated chromogenic carbohydrate model substrates for measuring activities of mucin-desulfating enzymes”: [Carbohydrate Research2002, 337, 1095–1111]
K. Clinch, G. B. Evans, R. Furneaux, P. M. Rendle +5 more
20020 citations Open access
Semantic Scholar
Separatory and Analytical Methods. Part 1. Chromatographic Methods
R. Ferrier, R. Blattner, K. Clinch, R. Furneaux +4 more
19970 citations
Semantic Scholar
Inorganic Derivatives. Part 1. Carbon-Bonded Phosphorus Derivatives
R. Ferrier, R. Blattner, K. Clinch, R. Furneaux +4 more
19970 citations
Semantic Scholar
Antibiotics. Part 1. Aminoglycosides and Aminocyclitol Derivatives
R. Ferrier, R. Blattner, K. Clinch, R. Furneaux +4 more
19970 citations
Semantic Scholar
NMR Spectroscopy and Conformational Features of Sugars
R. Ferrier, R. Blattner, K. Clinch, R. Furneaux +4 more
19970 citations
Semantic Scholar

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