F. Lézot

Most-cited papers

1. The contribution of immune infiltrates and the local microenvironment in the pathogenesis of osteosarcoma.

   M. Heymann, F. Lézot, D. Heymann

   2017Cellular Immunology208 citations Open access

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2. Dormant, quiescent, tolerant and persister cells: Four synonyms for the same target in cancer

   F. Vallette, C. Olivier, F. Lézot, L. Oliver +4 more

   2019Biochemical Pharmacology170 citations Open access

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3. RANK–RANKL signalling in cancer

   N. Renema, Benjamin Navet, M. Heymann, F. Lézot +1 more

   2016Bioscience Reports156 citations Open access

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4. Bone tissue formation with human mesenchymal stem cells and biphasic calcium phosphate ceramics: the local implication of osteoclasts and macrophages.

   Anne-laure Gamblin, M. Brennan, Audrey Renaud, H. Yagita +4 more

   2014Biomaterials147 citations Open access

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5. The twin cytokines interleukin-34 and CSF-1: masterful conductors of macrophage homeostasis

   J. Muñoz-García, D. Cochonneau, Stéphane Téletchéa, Emilie Moranton +5 more

   2021Theranostics142 citations Open access

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6. Endogenous Msx1 antisense transcript: In vivo and in vitro evidences, structure, and potential involvement in skeleton development in mammals

   Claudine Blin-Wakkach, F. Lézot, S. Ghoul-Mazgar, D. Hotton +8 more

   2001Proceedings of the National Academy of Sciences of the United States of America138 citations Open access

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7. Advances in Osteosarcoma

   Isidora Panez-Toro, J. Muñoz-García, J. W. Vargas-Franco, Axelle Renodon-Cornière +3 more

   2023Current Osteoporosis Reports104 citations Open access

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8. Msx2 -/- transgenic mice develop compound amelogenesis imperfecta, dentinogenesis imperfecta and periodental osteopetrosis.

   M. Aioub, F. Lézot, M. Molla, B. Castañeda +4 more

   2007Bone92 citations

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9. BYL719, a new α‐specific PI3K inhibitor: Single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma

   Bérengère Gobin, Marc Baud' Huin, F. Lamoureux, B. Ory +7 more

   2015International Journal of Cancer71 citations Open access

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10. Receptor activator of NF-κB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit

    Vincent Duheron, Estelle Hess, M. Duval, M. Decossas +12 more

    2011Proceedings of the National Academy of Sciences of the United States of America67 citations Open access

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11. Expression pattern of Dlx3 during cell differentiation in mineralized tissues.

    S. Ghoul-Mazgar, D. Hotton, F. Lézot, Claudine Blin-Wakkach +3 more

    2005Bone67 citations

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12. Physiological implications of DLX homeoproteins in enamel formation

    F. Lézot, B. Thomas, Scott R. Greene, D. Hotton +7 more

    2008Journal of Cellular Physiology64 citations

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13. In situ investigation of vitamin D receptor, alkaline phosphatase, and osteocalcin gene expression in oro-facial mineralized tissues.

    J. Davideau, P. Papagerakis, D. Hotton, F. Lézot +1 more

    1996Endocrinology60 citations

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14. Expression and regulation of the Msx1 natural antisense transcript during development

    A. Coudert, L. Pibouin, B. Vi-Fane, B. Thomas +6 more

    2005Nucleic Acids Research59 citations Open access

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15. Msx1 Is a Regulator of Bone Formation During Development and Postnatal Growth: In Vivo Investigations in a Transgenic Mouse Model

    S. Orestes-Cardoso, J. Nefussi, F. Lézot, M. Oboeuf +4 more

    2002Connective Tissue Research57 citations

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16. Differential Expression and Activity of Tissue-nonspecific Alkaline Phosphatase (TNAP) in Rat Odontogenic Cells In Vivo

    D. Hotton, N. Mauro, F. Lézot, N. Forest +1 more

    1999Journal of Histochemistry and Cytochemistry57 citations Open access

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17. Paradoxical side effects of bisphosphonates on the skeleton: What do we know and what can we do?

    J. W. Vargas-Franco, B. Castañeda, F. Redini, David F. Gomez +2 more

    2018Journal of Cellular Physiology56 citations

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18. Epithelial Dlx-2 Homeogene Expression and Cementogenesis

    F. Lézot, J. Davideau, B. Thomas, P. Sharpe +2 more

    2000Journal of Histochemistry and Cytochemistry56 citations Open access

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19. RANK/RANKL/OPG Signalization Implication in Periodontitis: New Evidence from a RANK Transgenic Mouse Model

    Bouchra Sojod, D. Château, C. Mueller, S. Babajko +3 more

    2017Frontiers in Physiology54 citations Open access

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20. Bone resorption control of tooth eruption and root morphogenesis: Involvement of the receptor activator of NF‐κB (RANK)

    B. Castañeda, Y. Simon, Jaime A. Jacques, Estelle Hess +5 more

    2011Journal of Cellular Physiology52 citations

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21. The Intrinsic and Extrinsic Implications of RANKL/RANK Signaling in Osteosarcoma: From Tumor Initiation to Lung Metastases

    Benjamin Navet, K. Ando, J. W. Vargas-Franco, R. Brion +9 more

    2018Cancers49 citations Open access

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22. Enamel protein regulation and dental and periodontal physiopathology in MSX2 mutant mice.

    M. Molla, V. Descroix, M. Aioub, S. Simon +7 more

    2010American Journal of Pathology44 citations Open access

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23. Skeletal consequences of RANKL-blocking antibody (IK22-5) injections during growth: mouse strain disparities and synergic effect with zoledronic acid.

    F. Lézot, J. Chesneau, Benjamin Navet, Bérengère Gobin +8 more

    2015Bone33 citations

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24. Dental alveolar bone defects related to Vitamin D and calcium status.

    J. Davideau, F. Lézot, S. Kato, I. Bailleul‐Forestier +1 more

    2004Journal of Steroid Biochemistry and Molecular Biology31 citations

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25. Preclinical evidence of potential craniofacial adverse effect of zoledronic acid in pediatric patients with bone malignancies.

    F. Lézot, J. Chesneau, S. Battaglia, R. Brion +4 more

    2014Bone30 citations

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26. Ribosomopathies: New Therapeutic Perspectives

    Emilien Orgebin, F. Lamoureux, B. Isidor, C. Charrier +3 more

    2020Cells29 citations Open access

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27. Small animal models for the study of bone sarcoma pathogenesis:characteristics, therapeutic interests and limitations

    C. Jacques, N. Renema, F. Lézot, B. Ory +3 more

    2018Journal of Bone Oncology29 citations Open access

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28. Physiopathology of Dental Rickets in Vitamin D Receptor-ablated Mice

    V. Descroix, S. Kato, F. Lézot, Ariane Berdal

    2010Journal of dentistry research29 citations

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29. Evidence for regulation of amelogenin gene expression by 1,25‐dihydroxyvitamin D3 in vivo

    P. Papagerakis, D. Hotton, F. Lézot, S. Brookes +4 more

    2000Journal of Cellular Biochemistry29 citations

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30. Bone resorption: an actor of dental and periodontal development?

    Andrea Gama, Benjamin Navet, J. Vargas, B. Castañeda +1 more

    2015Frontiers in Physiology24 citations Open access

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31. SHH Signaling Pathway Drives Pediatric Bone Sarcoma Progression

    F. Lézot, I. Corre, Sarah Morice, F. Redini +1 more

    2020Cells22 citations Open access

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32. Severe compromise of preosteoblasts in a surgical mouse model of bisphosphonate-associated osteonecrosis of the jaw.

    L. Córdova, Florian Guilbaud, J. Amiaud, S. Battaglia +5 more

    2016Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery22 citations Open access

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33. Bisphosphonates in common pediatric and adult bone sarcomas.

    M. Heymann, F. Lézot, D. Heymann

    2020Bone21 citations Open access

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34. Differential Impact of Msx1 and Msx2 Homeogenes on Mouse Maxillofacial Skeleton

    A. Berdal, M. Molla, D. Hotton, M. Aioub +3 more

    2008Cells Tissues Organs21 citations

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35. ICG-001, an Inhibitor of the β-Catenin and cAMP Response Element-Binding Protein Dependent Gene Transcription, Decreases Proliferation but Enhances Migration of Osteosarcoma Cells

    Geoffroy Danieau, Sarah Morice, Sarah Renault, R. Brion +8 more

    2021Pharmaceuticals20 citations Open access

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36. Vitamin D and tissue non-specific alkaline phosphatase in dental cells.

    F. Lézot, V. Descroix, D. Hotton, N. Mauro +2 more

    2006European Journal of Oral Sciences19 citations

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37. Cephalometric assessment of craniofacial dysmorphologies in relation with Msx2 mutations in mouse.

    Y. Simon, A. Marchadier, M. K. Riviere, K. van Damme +7 more

    2014Orthodontics & craniofacial research16 citations

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38. SKCa- and Kv1-type potassium channels and cancer: promising therapeutic targets ?

    Maryne Dupuy, M. Guéguinou, M. Potier-Cartereau, F. Lézot +5 more

    2023Biochemical Pharmacology15 citations Open access

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39. Sonic Hedgehog Signature in Pediatric Primary Bone Tumors: Effects of the GLI Antagonist GANT61 on Ewing’s Sarcoma Tumor Growth

    Mathilde Mullard, Marie Cadé, Sarah Morice, Maryne Dupuy +12 more

    2020Cancers13 citations Open access

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40. CHAPTER 34 – Dento-alveolar Bone Complex and Vitamin D

    A. Berdal, I. Bailleul‐Forestier, J. Davideau, F. Lézot

    200513 citations

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41. Role of RANKL (TNFSF11)-Dependent Osteopetrosis in the Dental Phenotype of Msx2 Null Mutant Mice

    B. Castañeda, Y. Simon, D. Ferbus, B. Robert +4 more

    2013PLoS ONE12 citations Open access

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42. Osteoclasts in the Dental Microenvironment: A Delicate Balance Controls Dental Histogenesis

    Ariane Berdal, B. Castañeda, M. Aioub, J. Nefussi +3 more

    2011Cells Tissues Organs11 citations

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43. Does Vitamin D play a role on Msx1 homeoprotein expression involving an endogenous antisense mRNA?

    F. Lézot, A. Coudert, S. Petit, B. Vi-Fane +6 more

    2004Journal of Steroid Biochemistry and Molecular Biology11 citations

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44. Genetically-achieved disturbances to the expression levels of TNFSF11 receptors modulate the effects of zoledronic acid on growing mouse skeletons.

    J. W. Vargas-Franco, B. Castañeda, Andrea Gama, C. Mueller +3 more

    2019Biochemical Pharmacology10 citations Open access

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45. Nasal inverted papilloma expresses the muscle segment homeobox gene Msx2: possible prognostic implications.

    J. Depondt, El‐Hassan Shabana, F. Walker, L. Pibouin +2 more

    2008Human Pathology10 citations

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46. Pharmacological options in the treatment of osteogenesis imperfecta: a comprehensive review of clinical and potential alternatives.

    J. Muñoz-García, D. Heymann, I. Giurgea, M. Legendre +4 more

    2023Biochemical Pharmacology8 citations Open access

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47. Maternal RANKL Reduces the Osteopetrotic Phenotype of Null Mutant Mouse Pups

    Benjamin Navet, J. W. Vargas-Franco, Andrea Gama, J. Amiaud +7 more

    2018Journal of Clinical Medicine7 citations Open access

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48. [Mineralized dental tissues: a unique example of skeletal biodiversity derived from cephaic neural crest].

    A. Berdal, F. Lézot, J. Nefussi, J. Sautier

    2000Morphologie : bulletin de l'Association des anatomistes7 citations

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49. Proteoglycans and osteolysis.

    M. Baud'huin, C. Charrier, G. Bougras, R. Brion +3 more

    2012Methods in molecular biology6 citations Open access

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50. Primary Retention of Molars and RANKL Signaling Alteration during Craniofacial Growth

    Andrea Gama, L. Maman, J. W. Vargas-Franco, Rana Omar +8 more

    2020Journal of Clinical Medicine5 citations Open access

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