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S. Wong · SciRah

Researcher profile · Semantic Scholar

S. Wong

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S. Wong — researcher profile on SciRah

h-index: 28
Works: 72
Citations: 4,034

Most-cited papers

Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia
A. Roberts, M. Davids, J. Pagel, B. Kahl +15 more
2015New England Journal of Medicine1,743 citations Open access
Semantic Scholar
Management of Venetoclax-Posaconazole Interaction in Acute Myeloid Leukemia Patients: Evaluation of Dose Adjustments.
S. Agarwal, C. Dinardo, J. Potluri, M. Dunbar +6 more
2017Clinical Therapeutics220 citations
Semantic Scholar
Pharmacokinetics of Venetoclax, a Novel BCL‐2 Inhibitor, in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Non‐Hodgkin Lymphoma
A. Salem, S. Agarwal, M. Dunbar, Sari L. Heitner Enschede +2 more
2017Journal of clinical pharmacology131 citations
Semantic Scholar
Microdialysis Calibration Using Retrodialysis and Zero-Net Flux: Application to a Study of the Distribution of Zidovudine to Rabbit Cerebrospinal Fluid and Thalamus
Yan-Feng Wang, S. Wong, R. Sawchuk
1993Pharmaceutical Research128 citations
Semantic Scholar
Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor.
K. F. McDaniel, Le Wang, Todd Soltwedel, S. Fidanze +28 more
2017Journal of Medicinal Chemistry122 citations Open access
Semantic Scholar
Effects of TD-5108 on Gastrointestinal Transit and Bowel Function in Health and Pharmacokinetics in Health and Constipation
M. Manini, M. Camilleri, M. R. Goldberg, S. Sweetser +6 more
2009Neurogastroenterology and Motility114 citations Open access
Semantic Scholar
Clinical Predictors of Venetoclax Pharmacokinetics in Chronic Lymphocytic Leukemia and Non-Hodgkin’s Lymphoma Patients: a Pooled Population Pharmacokinetic Analysis
A. Jones, K. Freise, S. Agarwal, R. Humerickhouse +2 more
2016AAPS Journal97 citations
Semantic Scholar
Effect of ketoconazole, a strong CYP3A inhibitor, on the pharmacokinetics of venetoclax, a BCL‐2 inhibitor, in patients with non‐Hodgkin lymphoma
S. Agarwal, A. Salem, A. Danilov, Beibei Hu +5 more
2017British Journal of Clinical Pharmacology91 citations Open access
Semantic Scholar
Evaluation of Rifampin's Transporter Inhibitory and CYP3A Inductive Effects on the Pharmacokinetics of Venetoclax, a BCL‐2 Inhibitor: Results of a Single‐ and Multiple‐Dose Study
S. Agarwal, Beibei Hu, D. Chien, S. Wong +1 more
2016Journal of clinical pharmacology86 citations
Semantic Scholar
Metabolism and Disposition of a Novel B-Cell Lymphoma-2 Inhibitor Venetoclax in Humans and Characterization of Its Unusual Metabolites
Hong Liu, Melissa J. Michmerhuizen, Yan-Bin Lao, Katty X. Wan +10 more
2017Drug Metabolism And Disposition83 citations Open access
Semantic Scholar
Effect of Low‐ and High‐Fat Meals on the Pharmacokinetics of Venetoclax, a Selective First‐in‐Class BCL‐2 Inhibitor
A. Salem, S. Agarwal, M. Dunbar, Silpa Nuthalapati +3 more
2016Journal of clinical pharmacology83 citations
Semantic Scholar
Leptin hormonal kinetics in the fed state: effects of adiposity, age, and gender on endogenous leptin production and clearance rates.
S. Wong, A. DePaoli, Jennifer Lee, C. Mantzoros
2004Journal of Clinical Endocrinology and Metabolism64 citations
Semantic Scholar
Impact of Venetoclax Exposure on Clinical Efficacy and Safety in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia
K. Freise, A. Jones, D. Eckert, S. Mensing +4 more
2017Clinical Pharmacokinetics61 citations
Semantic Scholar
Multiple-dose pharmacokinetics of intravenous telavancin in healthy male and female subjects.
S. Wong, S. Barriere, M. Kitt, M. Goldberg
2008Journal of Antimicrobial Chemotherapy53 citations Open access
Semantic Scholar
Pharmacokinetics of Subcutaneous Recombinant Methionyl Human Leptin Administration in Healthy Subjects in the Fed and Fasting States
J. Chan, S. Wong, C. Mantzoros
2008Clinical Pharmacokinetics49 citations Open access
Semantic Scholar
Evaluation of the Pharmacokinetic Interaction between Venetoclax, a Selective BCL-2 Inhibitor, and Warfarin in Healthy Volunteers
A. Salem, Beibei Hu, K. Freise, S. Agarwal +2 more
2017Clinical drug investigation46 citations
Semantic Scholar
Effects of divalproex sodium on amitriptyline and nortriptyline pharmacokinetics
S. Wong, J. Cavanaugh, Harry H. Shi, W. Awni +1 more
1996Clinical pharmacology and therapy46 citations
Semantic Scholar
Analysis of Zidovudine Distribution to Specific Regions in Rabbit Brain Using Microdialysis
S. Wong, Yan-Feng Wang, R. Sawchuk
1992Pharmaceutical Research40 citations
Semantic Scholar
Pharmacokinetics of sertindole and dehydrosertindole in volunteers with normal or impaired renal function
S. Wong, S. Menacherry, D. Mulford, P. Schmitz +2 more
1997European Journal of Clinical Pharmacology39 citations
Semantic Scholar
A Dose-Escalation Study of Venetoclax (ABT-199/GDC-0199) in Combination with Bendamustine and Rituximab in Patients with Relapsed or Refractory Non-Hodgkin's Lymphoma
S. de Vos, L. Swinnen, M. Kozloff, Ding Wang +13 more
201535 citations
Semantic Scholar
[O-ethyl 14C]phenacetin O-deethylase activity in human liver microsomes.
A. Rodrigues, B. W. Surber, Y. Yao, S. Wong +1 more
1997Drug Metabolism And Disposition34 citations
Semantic Scholar
EXPANDED VERSION OF PKSIM FOR PHARMACOKINETIC SIMULATIONS OF BOTH METABOLITE AND PARENT DRUGS
Ronald C. Li, S. Wong, K. Chan
1997American Journal of Therapeutics32 citations
Semantic Scholar
Pharmacokinetics of recombinant methionyl human leptin after subcutaneous administration: variation of concentration-dependent parameters according to assay.
J. Chan, S. Wong, Christine Orlova, Patricia Raciti +1 more
2007Journal of Clinical Endocrinology and Metabolism31 citations
Semantic Scholar
Pharmacokinetics of sertindole in healthy young and elderly male and female subjects
S. Wong, G. Cao, R. Mack, G. Granneman
1997Clinical pharmacology and therapy31 citations
Semantic Scholar
The Pharmacokinetics of Single Oral Doses of Zileuton 200 to 800mg, its Enantiomers, and its Metabolites, in Normal Healthy Volunteers
S. Wong, W. Awni, J. Cavanaugh, T. El-Shourbagy +2 more
1995Clinical Pharmacokinetics31 citations
Semantic Scholar
Population Pharmacokinetics of Telavancin in Healthy Subjects and Patients with Infections
E. Samara, J. Shaw, S. Barriere, S. Wong +1 more
2012Antimicrobial Agents and Chemotherapy30 citations Open access
Semantic Scholar
Safety and pharmacodynamics of venetoclax (ABT-199) in a randomized single and multiple ascending dose study in women with systemic lupus erythematosus
P. Lu, R. Fleischmann, C. Curtis, S. Ignatenko +8 more
2018Lupus29 citations
Semantic Scholar
Pharmacokinetics and Metabolism of Diclofenac Sodium in Yucatan Miniature Pigs
R. Oberle, H. Das, S. Wong, K. Chan +1 more
1994Pharmaceutical Research29 citations
Semantic Scholar
Phase 1, open-label, dose-escalation, and expansion study of ABT-700, an anti-C-met antibody, in patients (pts) with advanced solid tumors.
J. Strickler, P. LoRusso, Jui-Yen Chia, Chia-Chi Lin +8 more
201427 citations
Semantic Scholar
Effect of Telavancin on the Pharmacokinetics of the Cytochrome P450 3A Probe Substrate Midazolam: A Randomized, Double‐Blind, Crossover Study in Healthy Subjects
S. Wong, M. R. Goldberg, Charles H. Ballow, M. Kitt +1 more
2010Pharmacotherapy26 citations
Semantic Scholar
Modeling of sertindole pharmacokinetic disposition in healthy volunteers in short term dose-escalation studies.
S. Wong, G. Granneman
1998Journal of Pharmacy and Science26 citations
Semantic Scholar
EFFECTS OF FOOD, ANTACID, AND DOSAGE FORM ON THE PHARMACOKINETICS AND RELATIVE BIOAVAILABILITY OF SERTINDOLE IN HEALTHY VOLUNTEERS
S. Wong, P. Linnen, R. Mack, G. Granneman
1997Biopharmaceutics & drug disposition26 citations
Semantic Scholar
Venetoclax does not prolong the QT interval in patients with hematological malignancies: an exposure–response analysis
K. Freise, M. Dunbar, A. Jones, David Hoffman +3 more
2016Cancer Chemotherapy and Pharmacology25 citations
Semantic Scholar
Single‐Dose Pharmacokinetics and Tolerability of Telavancin in Elderly Men and Women
M. R. Goldberg, S. Wong, J. Shaw, M. Kitt +1 more
2010Pharmacotherapy25 citations
Semantic Scholar
Pharmacokinetics of intravenous telavancin in healthy subjects with varying degrees of renal impairment
P. Worboys, S. Wong, S. Barriere
2015European Journal of Clinical Pharmacology23 citations Open access
Semantic Scholar
Lack of Effect of Moderate Hepatic Impairment on the Pharmacokinetics of Telavancin
M. R. Goldberg, S. Wong, J. Shaw, M. Kitt +1 more
2010Pharmacotherapy22 citations
Semantic Scholar
Clinical pharmacodynamic/exposure characterisation of the multikinase inhibitor ilorasertib (ABT-348) in a phase 1 dose-escalation trial
M. Maitland, S. Piha-Paul, G. Falchook, R. Kurzrock +13 more
2018British Journal of Cancer21 citations Open access
Semantic Scholar
Lack of Pharmacokinetic Drug Interactions Following Concomitant Administration of Telavancin with Aztreonam or Piperacillin/Tazobactam in Healthy Participants
S. Wong, F. Sörgel, M. Kinzig, M. Goldberg +2 more
2009Journal of clinical pharmacology20 citations
Semantic Scholar
Phase I Dose-Escalation and -Expansion Study of Telisotuzumab (ABT-700), an Anti–c-Met Antibody, in Patients with Advanced Solid Tumors
J. Strickler, P. LoRusso, R. Salgia, Yoon-Koo Kang +11 more
2020Molecular Cancer Therapeutics19 citations Open access
Semantic Scholar
First-in-Human Phase I Study of ABBV-838, an Antibody–Drug Conjugate Targeting SLAMF7/CS1 in Patients with Relapsed and Refractory Multiple Myeloma
R. Vij, R. Nath, D. Afar, M. Mateos +15 more
2020Clinical Cancer Research19 citations
Semantic Scholar
Pharmacokinetics and Pharmacodynamics of a Novel Depot Formulation of Abarelix, a Gonadotropin‐Releasing Hormone (GnRH) Antagonist, in Healthy Men Ages 50 to 75
S. Wong, D. Lau, S. Baughman, N. Fotheringham +2 more
2004Journal of clinical pharmacology17 citations
Semantic Scholar
Pharmacokinetics and pharmacodynamics of abarelix, a gonadotropin‐releasing hormone antagonist, after subcutaneous continuous infusion in patients with prostate cancer
S. Wong, David Lau, S. Baughman, D. Menchaca +1 more
2003Clinical pharmacology and therapy17 citations
Semantic Scholar
Pharmacokinetics of Zileuton and Its Metabolites in Patients with Renal Impairment
W. Awni, S. Wong, S. Chu, K. Patterson +5 more
1997Journal of clinical pharmacology16 citations
Semantic Scholar
Application of human liver microsomes in metabolism-based drug-drug interactions: in vitro-in vivo correlations and the Abbott Laboratories experience.
A. Rodrigues, S. Wong
1997Advances in Pharmacology16 citations
Semantic Scholar
The Effect of Erythromycin on the CYP3A Component of Sertindole Clearance in Healthy Volunteers
S. Wong, G. Cao, R. Mack, Witt +1 more
1997Journal of clinical pharmacology14 citations
Semantic Scholar
Ph1/2 study of Rova-T in combination with nivolumab (Nivo) ± ipilimumab (Ipi) for patients (pts) with 2L+ extensive-stage (ED) SCLC.
J. Malhotra, P. Nikolinakos, T. Leal, J. Lehman +16 more
2019Journal of Clinical Oncology12 citations
Semantic Scholar
A phase III study of rovalpituzumab tesirine maintenance therapy following first-line platinum-based chemotherapy in patients with extensive disease small cell lung cancer (ED SCLC).
P. Komarnitsky, Ho-Jin Lee, M. Shah, S. Wong +4 more
201711 citations
Semantic Scholar
Phase 1, open-label, dose-escalation and expansion study of ABBV-399, an antibody drug conjugate (ADC) targeting c-Met, in patients (pts) with advanced solid tumors.
J. Strickler, J. Nemunaitis, C. Weekes, R. Ramanathan +12 more
20169 citations
Semantic Scholar
Competitive Inhibition of Zidovudine Clearance by Probenecid During Continuous Coadministration
S. Wong, M. Hedaya, R. Sawchuk
1992Pharmaceutical Research8 citations
Semantic Scholar
Pharmacokinetics and pharmacodynamics of single and multiple oral doses of a novel 5‐lipoxygenase inhibitor (ABT‐761) in healthy volunteers
S. Wong, J. Drajesk, Min Chang, C. Lanni +3 more
1998Clinical pharmacology and therapy7 citations
Semantic Scholar

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W. Awni — researcher profile on SciRah

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