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Z. Pittel · SciRah

Researcher profile · Semantic Scholar

Z. Pittel

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Z. Pittel — researcher profile on SciRah

h-index: 22
Works: 55
Citations: 1,683

Most-cited papers

Activity-dependent neuroprotective protein: a novel gene essential for brain formation.
A. Pinhasov, S. Mandel, A. Torchinsky, E. Giladi +5 more
2003Brain research. Developmental brain research243 citations
Semantic Scholar
Activity-Dependent Neuroprotective Protein Snippet NAP Reduces Tau Hyperphosphorylation and Enhances Learning in a Novel Transgenic Mouse Model
I. Vulih-Shultzman, A. Pinhasov, S. Mandel, N. Grigoriadis +3 more
2007Journal of Pharmacology and Experimental Therapeutics217 citations
Semantic Scholar
M1 muscarinic agonists can modulate some of the hallmarks in Alzheimer’s disease
A. Fisher, Z. Pittel, R. Haring, Nira Bar-Ner +6 more
2007Journal of Molecular Neuroscience135 citations
Semantic Scholar
Mitogen‐Activated Protein Kinase‐Dependent and Protein Kinase C‐Dependent Pathways Link the m1 Muscarinic Receptor to β‐Amyloid Precursor Protein Secretion
R. Haring, A. Fisher, D. Marciano, Z. Pittel +4 more
1998116 citations
Semantic Scholar
(+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3')quinuclidine, an M1 selective cholinergic agonist, attenuates cognitive dysfunctions in an animal model of Alzheimer's disease.
Abraham Fisher, R. Brandeis, I. Karton, Z. Pittel +5 more
1991Journal of Pharmacology and Experimental Therapeutics78 citations
Semantic Scholar
M1 Agonists for the Treatment of Alzheimer's Disease.
Abraham Fisher, E. Heldman, David Gurwitz, R. Haring +14 more
1996Annals of the New York Academy of Sciences71 citations
Semantic Scholar
(+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3') quinuclidine (AF102B): a new M1 agonist attenuates cognitive dysfunctions in AF64A-treated rats.
Abraham Fisher, R. Brandeis, Z. Pittel, I. Karton +4 more
1989Neuroscience Letters71 citations
Semantic Scholar
M1 Muscarinic Agonist Treatment Reverses Cognitive and Cholinergic Impairments of Apolipoprotein E‐Deficient Mice
A. Fisher, R. Brandeis, S. Chapman, Z. Pittel +1 more
1998Journal of Neurochemistry70 citations
Semantic Scholar
M1 Muscarinic Agonists as Potential Disease‐Modifying Agents in Alzheimer's Disease: Rationale and Perspectives
Abraham Fisher, Daniel M. Michaelson, R. Brandeis, R. Haring +2 more
2000Annals of the New York Academy of Sciences64 citations
Semantic Scholar
AF150(S) and AF267B
A. Fisher, R. Brandeis, Rachel Haring Nira Bar-Ner, M. Kliger-Spatz +4 more
2002Journal of Molecular Neuroscience50 citations
Semantic Scholar
Reversible and Irreversible Inhibition of High‐Affinity Choline Transport Caused by Ethylcholine Aziridinium Ion
Z. Pittel, A. Fisher, E. Heldman
1987Journal of Neurochemistry45 citations
Semantic Scholar
Muscarinic control of amyloid precursor protein secretion in rat cerebral cortex and cerebellum.
Z. Pittel, E. Heldman, J. Barg, R. Haring +1 more
1996Brain Research43 citations
Semantic Scholar
Amyloid precursor protein secretion via muscarinic receptors: reduced desensitization using the M1-selective agonist AF102B.
R. Haring, D. Gurwitz, J. Barg, R. Pinkas-Kramarski +7 more
1994Biochemical and Biophysical Research Communications - BBRC43 citations
Semantic Scholar
NGF promotes amyloid precursor protein secretion via muscarinic receptor activation.
R. Haring, David Gurwitz, J. Barg, Ronit Pinkas-Kramarski +8 more
1995Biochemical and Biophysical Research Communications - BBRC34 citations
Semantic Scholar
Selective Signaling via Unique Ml Muscarinic Agonists a
A. Fisher, E. Heldman, D. Gurwitz, R. Haring +8 more
1993Annals of the New York Academy of Sciences34 citations
Semantic Scholar
Distinct Muscarinic Receptor Subtypes Differentially Modulate Acetylcholine Release from Corticocerebral Synaptosomes
Z. Pittel, E. Heldman, Rachel Rubinstein, Sasson Cohen
1990Journal of Neurochemistry33 citations
Semantic Scholar
AF150(S) and AF267B: M1 muscarinic agonists as innovative therapies for Alzheimer's disease.
A. Fisher, R. Brandeis, Rachel Haring Nira Bar-Ner, M. Kliger-Spatz +4 more
2002Journal of Molecular Neuroscience32 citations
Semantic Scholar
Pharmacological basis for functional selectivity of partial muscarinic receptor agonists.
Eliahu Heldman, J. Barg, Abraham Fisher, Rivka Levy +4 more
1996European Journal of Pharmacology27 citations
Semantic Scholar
AF64A Induced Cholinotoxicity: Behavioral and Biochemical Correlates
R. Brandeis, Z. Pittel, C. Lachman, E. Heldman +5 more
198625 citations
Semantic Scholar
Endocannabinoid Receptor Deficiency Affects Maternal Care and Alters the Dam's Hippocampal Oxytocin Receptor and Brain‐Derived Neurotrophic Factor Expression
M. Schechter, A. Weller, Z. Pittel, M. Gross +2 more
2013Journal of neuroendocrinology24 citations
Semantic Scholar
Intramolecular interactions in muscarinic acetylcholine receptors studied with chimeric m2/m5 receptors.
Z. Pittel, J. Wess
1994Molecular Pharmacology24 citations
Semantic Scholar
Mitogen-activated protein kinase-dependent and protein kinase C-dependent pathways link the m1 muscarinic receptor to beta-amyloid precursor protein secretion.
R. Haring, A. Fisher, D. Marciano, Z. Pittel +4 more
1998Journal of Neurochemistry23 citations
Semantic Scholar
Dehydroepiandrosterone (DHEA) increases production and release of Alzheimer's amyloid precursor protein.
H. Danenberg, R. Haring, Abraham Fisher, Z. Pittel +2 more
1996Life Science22 citations
Semantic Scholar
Dehydroepiandrosterone Augments M1‐Muscarinic Receptor‐Stimulated Amyloid Precursor Protein Secretion in Desensitized PC12M1 Cells
H. Danenberg, R. Haring, Eliahu Heldman, David Gurwitz +4 more
1995Annals of the New York Academy of Sciences19 citations
Semantic Scholar
Cholinotoxicity of the ethylcholine aziridinium ion in primary cultures from rat central nervous system.
A. Amir, Z. Pittel, A. Shahar, A. Fisher +1 more
1988Brain Research17 citations
Semantic Scholar
Progress in medicinal chemistry of novel selective muscarinic agonists.
Abraham Fisher, Y. Karton, Eliahu Heldman, David Gurwitz +6 more
1993Drug Design and Discovery16 citations
Semantic Scholar
Impact of muscarinic agonists for successful therapy of Alzheimer's disease.
Abraham Fisher, R. Brandeis, R. Haring, Nira Bar-Ner +5 more
2002Journal of neural transmission. Supplementum15 citations
Semantic Scholar
Novel m1 muscarinic agonists in treatment and delaying the progression of Alzheimer's disease: an unifying hypothesis.
A. Fisher, R. Brandeis, R. Haring, N. Eshhar +7 more
1998Journal of Physiology - Paris14 citations
Semantic Scholar
AF102B: rational treatment strategy for Alzheimer's disease: recent advances.
Abraham Fisher, R. Brandeis, I. Karton, Z. Pittel +5 more
1990Advances in neurology13 citations
Semantic Scholar
Rigid analogs of acetylcholine can be m1-selective agonists: implications for a rational treatment strategy in Alzheimer's disease
A. Fisher, D. Gurwitz, D. Barak, R. Haring +7 more
19929 citations
Semantic Scholar
Early changes in M2 muscarinic acetylcholine receptors (mAChRs) induced by sarin intoxication may be linked to long lasting neurological effects
Z. Pittel, Shlomi Lazar, Rellie Gez, S. Chapman
2017Neurotoxicology7 citations
Semantic Scholar
Function-specific blockage of M(1) and M(3) muscarinic acetylcholine receptors by VX and echothiophate.
Z. Pittel, D. Barak, Y. Segall
2006Brain Research7 citations
Semantic Scholar
Selective Signaling Via Novel Muscarinic Agonists: Implications for Alzheimer’s Disease Treatments and Clinical Update
A. Fisher, E. Heldman, D. Gurwitz, R. Haring +10 more
19947 citations
Semantic Scholar
Differential long-term effect of AF64A on [3H]ACh synthesis and release in rat hippocampal synaptosomes.
Z. Pittel, Sasson Cohen, A. Fisher, E. Heldman
1992Brain Research6 citations
Semantic Scholar
Cholinotoxicity induced by ethylcholine aziridinium ion after intracarotid and intracerebroventricular administration.
Z. Pittel, Abraham Fisher, Eliahu Heldman
1989Life Science6 citations
Semantic Scholar
Early perceptual loss in depression
C. Abramovitch-Dahan, E. Beit-Yannai, S. Ben-Shabat, Y. Abu-Ghanem +496 more
20075 citations Open access
Semantic Scholar
M1 muscarinic agonists protect PC12M1 cells from growth factor deprivation and β-amyloids-induced apoptosis
R. Haring, O. Eizenberg, Z. Pittel, A. Fisher
20004 citations
Semantic Scholar
New M1 Agonists: Selective Signaling, Neurotrophic-Like and Cognitive Effects — Implications in the Treatment of Alzheimer’s Disease
A. Fisher, E. Heldman, D. Gurwitz, R. Haring +8 more
19954 citations
Semantic Scholar
Inhibition of choline efflux results in enhanced acetylcholine synthesis and release in the guinea-pig corticocerebral synaptosomes.
Z. Pittel, E. Heldman, Rachel Rubinstein, Sasson Cohen
1992Neurochemistry International4 citations
Semantic Scholar
Selective lesion of neurons in primary cell cultures by MPTP and ethylcholine aziridinium ion (AF64A).
A. Amir, A. Shahar, Z. Pittel, A. Korczyn +2 more
1987Progress in clinical and biological research2 citations
Semantic Scholar
21 Concomitant activation of G-protein coupled receptors (GPCR) and sigma1 receptor (Sig1R): a novel pharmacological concept in treatment of Alzheimer's disease (AD)
A. Fisher, N. Natan, H. Elkon, R. Brandeis +3 more
20121 citations
Semantic Scholar
M1 Muscarinic Agonists as a Therapeutic Strategy in Alzheimer’s Disease
A. Fisher, Z. Pittel, R. Haring, R. Brandeis +6 more
20021 citations
Semantic Scholar
AF102B: A Novel M1 Agonist as a Rational Treatment Strategy in Alzheimer’s Disease
A. Fisher, R. Brandeis, I. Karton, Z. Pittel +5 more
19891 citations
Semantic Scholar
Friday, March 16, 2007. pp. 97–134
A. Caccamo, S. Oddo, L. Billings, K. Green +11 more
2007Neurodegenerative Diseases0 citations
Semantic Scholar
S2-04-01 The therapeutic potential of M1 muscarinic agonists in Alzheimer's disease (AD) and cerebral amyloid angiopathy (CAA)
A. Fisher, Z. Pittel, R. Brandeis, T. Beach +6 more
20040 citations
Semantic Scholar
Beta-amyloids, tau hyperphosphorylation and cognition are beneficially affected by M1 muscarinic agonists: perspectives in Alzheimer’s disease treatment
Z. Pittel, R. Haring, N. Bons, Nira Bar-Ner +4 more
20040 citations
Semantic Scholar
Effect of muscarinic stimulation on β-amyloid precursor protein processing in rat brain and primary cultures
Z. Pittel, A. Fisher, N. Eshhar, R. Haring +1 more
19990 citations
Semantic Scholar
The Molecular Basis Underlying the Discrete Activation of Signal Transduction Pathways by Selective Muscarinic Agonists
E. Heldman, Z. Pittel, R. Haring, N. Eshhar +5 more
19980 citations
Semantic Scholar
Muscarinic Modulation of β-Amyloid Precursor Protein (βApp) Processing in Vitro and in Vivo
Z. Pittel, Nomi Eshhar, E. Heldman, M. Sapir +3 more
19980 citations
Semantic Scholar
Ml Muscarinic Agonists: From Treatment Toward Delaying Progression of Alzheimer’s Disease
A. Fisher, R. Haring, Z. Pittel, Nomi Eshhar +5 more
19980 citations
Semantic Scholar

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E. Heldman×25
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R. Brandeis×24
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D. Marciano×11

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Y. Karton — researcher profile on SciRah

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N. Natan — researcher profile on SciRah

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I. Marcovitch — researcher profile on SciRah

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