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Lin Pan · SciRah

Researcher profile · Semantic Scholar

Lin Pan

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Lin Pan — researcher profile on SciRah

h-index: 5
Works: 17
Citations: 419

Most-cited papers

Preclinical Characteristics of the Hepatitis C Virus NS3/4A Protease Inhibitor ITMN-191 (R7227)
S. Seiwert, Steven W. Andrews, Yu-Tong Jiang, V. Serebryany +20 more
2008Antimicrobial Agents and Chemotherapy178 citations Open access
Semantic Scholar
Virological characteristics of the SARS-CoV-2 omicron XBB.1.16 variant
D. Yamasoba, K. Uriu, Arnon Plianchaisuk, Y. Kosugi +4 more
2023bioRxiv129 citations Open access
Semantic Scholar
In vitro assessment of cytochrome P450 inhibition: strategies for increasing LC/MS-based assay throughput using a one-point IC(50) method and multiplexing high-performance liquid chromatography.
Tong Lin, Kristine Pan, J. Mordenti, Lin Pan
2007Journal of Pharmacy and Science55 citations
Semantic Scholar
Factor VIIa inhibitors: a prodrug strategy to improve oral bioavailability.
J. Riggs, A. Kolesnikov, J. Hendrix, W. Young +8 more
2006Bioorganic & Medicinal Chemistry Letters27 citations Open access
Semantic Scholar
Danoprevir Monotherapy Decreases Inflammatory Markers in Patients with Chronic Hepatitis C Virus Infection
C. Schaefer, K. Kossen, Sharlene R. Lim, Jiing-Huey Lin +4 more
2011Antimicrobial Agents and Chemotherapy16 citations Open access
Semantic Scholar
Preclinical Characterization and Human Microdose Pharmacokinetics of ITMN-8187, a Nonmacrocyclic Inhibitor of the Hepatitis C Virus NS3 Protease
R. Rajagopalan, Lin Pan, C. Schaefer, J. B. Nicholas +15 more
2016Antimicrobial Agents and Chemotherapy5 citations Open access
Semantic Scholar
Discovery and Development of the HCV NS3/4A Protease Inhibitor Danoprevir (ITMN‐191/RG7227)
S. Seiwert, K. Kossen, Lin Pan, Jyanwei Liu +1 more
20115 citations
Semantic Scholar
1228 CHARACTERIZATION OF NOVEL, HIGHLY POTENT NS5A INHIBITORS WITH QD DOSING POTENTIAL AND ROBUST ACTIVITY IN AN HCV CHIMERIC ANIMAL MODEL
J. B. Nicholas, B. Buckman, V. Serebryany, C. Schaefer +11 more
20113 citations
Semantic Scholar
1073 ITMN-191/R7227 MONOTHERAPY IN CHRONIC HCV PATIENTS REDUCES PLASMA CONCENTRATIONS OF IP-10 AND NEOPTERIN
C. Schaefer, K. Kossen, Sharlene R. Lim, X. Qin +4 more
20101 citations
Semantic Scholar
Identification of Novel Small-Molecule LOXL2 Inhibitors by High Throughput Screening
J. B. Nicholas, K. Emayan, J. Ramphal, S. Misialek +8 more
20140 citations
Semantic Scholar
Discovery of ITMN-14440: A Pirfenidone Analog with Improved Pharmacokinetics, Anti-Fibrotic Efficacy and Reduced Gastric Side Effects
J. Ramphal, J. B. Nicholas, C. Schaefer, H. Ramesha +20 more
20140 citations
Semantic Scholar
Biochemical and functional characterization of lysyl oxidase like 2 (LOXL2) inhibitors
R. Rajagopalan, S. Misialek, Jin-Xin Huang, L. Hooi +9 more
2014European Respiratory Journal0 citations
Semantic Scholar
Combination of Pirfenidone and Nintedanib: Pharmacokinetics Upon Co-administration in Dogs
Yan Huang, S. Yap, Liang-Yu Liu, S. Seiwert +1 more
20140 citations
Semantic Scholar
Discovery and Anti-fibrotic Activity of Novel Antagonists of Lysophosphatidic Acid Receptor 1 (LPA1)
J. B. Nicholas, Jin-Xin Huang, L. Hooi, C. Schaefer +18 more
20140 citations
Semantic Scholar
1196 NOVEL, POTENT, PAN-GENOTYPIC HCV NS3/4A PROTEASE INHIBITORS WITH A HIGH BARRIER TO RESISTANCE
B. Buckman, K. Kossen, J. B. Nicholas, V. Serebryany +13 more
20110 citations Open access
Semantic Scholar
938 DISCOVERY OF POTENT, BIOAVAILABLE HCV NS3/4A INHIBITORS THAT DISPLAY UNIMPAIRED ACTIVITY AGAINST AN NS3 SEQUENCE VARIANT ASSOCIATED WITH RESISTANCE TO LINEAR TETRAPEPTIDES AND MACROCYCLIC INHIBITORS
B. Buckman, K. Kossen, D. Ruhrmund, R. Rajagopalan +11 more
20090 citations Open access
Semantic Scholar
342 A MOUSE MODEL WITH LONG TERM EXPRESSION OF HEPATITIS C VIRUS NS3/4A PROTEASE FOR THE PHARMACOKINETIC AND PHARMACODYNAMIC (PK/PD) STUDY OF HCV PROTEASE INHIBITORS
J. Lin, J. Hong, Sharlene R. Lim, X. Qin +6 more
20090 citations
Semantic Scholar

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