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A. Chirino · SciRah

Researcher profile · Semantic Scholar

A. Chirino

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A. Chirino — researcher profile on SciRah

h-index: 16
Works: 28
Citations: 3,629

Most-cited papers

Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor.
J. Lebrón, M. J. Bennett, D. Vaughn, A. Chirino +4 more
1998Cell631 citations Open access
Semantic Scholar
Efficiency of signalling through cytokine receptors depends critically on receptor orientation
R. Syed, S. W. Reid, Cui-Wei Li, J. Cheetham +14 more
1998Nature545 citations
Semantic Scholar
Characterizing biological products and assessing comparability following manufacturing changes
A. Chirino, A. Mire-Sluis
2004Nature Biotechnology357 citations
Semantic Scholar
Three-dimensional structures of acidic and basic fibroblast growth factors.
Xiao-Tian Zhu, H. Komiya, A. Chirino, S. Faham +4 more
1993Science342 citations
Semantic Scholar
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
S. Smerdon, J. Jáger, Ji-Min Wang, L. A. Kohlstaedt +4 more
1994Proceedings of the National Academy of Sciences of the United States of America307 citations Open access
Semantic Scholar
Structure of the reaction center from Rhodobacter sphaeroides R-26 and 2.4.1: protein-cofactor (bacteriochlorophyll, bacteriopheophytin, and carotenoid) interactions.
T. O. Yeates, H. Komiya, A. Chirino, D. C. Rees +2 more
1988Proceedings of the National Academy of Sciences of the United States of America258 citations Open access
Semantic Scholar
Inactivation of TNF Signaling by Rationally Designed Dominant-Negative TNF Variants
P. Steed, M. Tansey, J. Zalevsky, E. Zhukovsky +30 more
2003Science254 citations
Semantic Scholar
Rational design and engineering of therapeutic proteins.
S. A. Marshall, G. A. Lazar, A. Chirino, J. Desjarlais
2003Drug Discovery Today211 citations
Semantic Scholar
Minimizing the immunogenicity of protein therapeutics.
A. Chirino, M. L. Ary, S. A. Marshall
2004Drug Discovery Today182 citations
Semantic Scholar
Crystal structure of human ZAG, a fat-depleting factor related to MHC molecules.
Luis M. Sánchez, A. Chirino, P. Bjorkman
1999Science143 citations
Semantic Scholar
Crystal Structure of the Cysteine-Rich Domain of Mannose Receptor Complexed with a Sulfated Carbohydrate Ligand
Yang Liu, A. Chirino, Z. Misulovin, C. Leteux +3 more
2000Journal of Experimental Medicine123 citations Open access
Semantic Scholar
Crystallographic analyses of site-directed mutants of the photosynthetic reaction center from Rhodobacter sphaeroides.
A. Chirino, E. Lous, M. Huber, J. Allen +4 more
1994Biochemistry120 citations
Semantic Scholar
Crystallization and X-ray structure determination of cytochrome c2 from Rhodobacter sphaeroides in three crystal forms.
H. L. Axelrod, G. Feher, J. Allen, A. Chirino +3 more
1995Acta Crystallographica Section D: Biological Crystallography51 citations Open access
Semantic Scholar
Correlation between the 1.6 Å crystal structure and mutational analysis of keratinocyte growth factor
T. Osslund, R. Syed, E. Singer, E. Hsu +7 more
1998Protein Science40 citations Open access
Semantic Scholar
Crystallization and preliminary X-ray analysis of the major cellulose-binding domain of the cellulosome from Clostridium thermocellum.
R. Lamed, J. Tormo, A. Chirino, E. Morag +1 more
1994Journal of Molecular Biology36 citations Open access
Semantic Scholar
Membrane Protein Structure and Stability: Implications of the First Crystallographic Analyses
D. Rees, A. Chirino, K. Kim, H. Komiya
199417 citations
Semantic Scholar
Crystal Structures of the Iron Protein and Molybdenum-Iron Protein of Nitrogenase
D. Rees, Jongsun Kim, M. Georgiadis, H. Komiya +8 more
19935 citations
Semantic Scholar
State of the art analytical comparability: a review.
A. Chirino, A. Mire-Sluis
2005Developments in Biologicals4 citations
Semantic Scholar
Structures and Functions of the Nitrogenase Proteins
D. Rees, Jongsun Kim, M. Georgiadis, M. Chan +5 more
19934 citations
Semantic Scholar
Structure of the Reaction Center from Rhodobacter sphaeroides: Further Refinement of R-26 and 2.4.1 Structures and Interactions between the Reaction Center and Herbicides
J. Allen, E. Lous, G. Feher, A. Chirino +2 more
19901 citations
Semantic Scholar
Efficiencyofsignallingthrough cytokine receptors dependscriticallyon receptororientation
R. Syed, S. W. Reid, Cui-Wei Li, J. Cheetham +14 more
20060 citations
Semantic Scholar
Membres de la superfamille des tnf avec immunogenicite modifiee
S. Marshall, Gregory L. Moore, A. Chirino, John R. Desjarlais
20050 citations
Semantic Scholar
Optimized Fc variants and methods of forming thereof
G. A. Lazar, A. Chirino, W. Dang, J. Desjarlais +4 more
20030 citations
Semantic Scholar
Optimized variants of fc and methods for their generation
G. A. Lazar, A. Chirino, W. Dang, J. Desjarlais +4 more
20030 citations
Semantic Scholar
Determination of the Crystal Structure of Human Zn-Alpha 2-Gylcoprotein, A Protein Implicated in Breast Cancer
P. Bjorkman, A. Chirino
20000 citations Open access
Semantic Scholar
CRYSTAL STRUCTURE OF THE CYSTEINE RICH DOMAIN OF MANNOSE RECEPTOR
Yang Liu, A. Chirino, Z. Misulovin, C. Leteux +3 more
20000 citations
Semantic Scholar
HFE (HUMAN) HEMOCHROMATOSIS PROTEIN
J. Lebrón, M. J. Bennett, D. Vaughn, A. Chirino +4 more
19990 citations
Semantic Scholar
HUMAN ZINC-ALPHA-2-GLYCOPROTEIN
A. Chirino, Luis M. Sánchez, P. Bjorkman
19990 citations
Semantic Scholar

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