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K. Fairfax · SciRah

Researcher profile · Semantic Scholar

K. Fairfax

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K. Fairfax — researcher profile on SciRah

h-index: 25
Works: 49
Citations: 3,602

Most-cited papers

Single-cell eQTL mapping identifies cell type–specific genetic control of autoimmune disease
S. Yazar, José Alquicira-Hernández, K. Wing, A. Senabouth +13 more
2022Science574 citations Open access
Semantic Scholar
The BAFF/APRIL system: Emerging functions beyond B cell biology and autoimmunity
F. Vincent, Damien Saulep-Easton, William A. Figgett, K. Fairfax +1 more
2013Cytokine & growth factor reviews455 citations Open access
Semantic Scholar
NK Cell Maturation and Peripheral Homeostasis Is Associated with KLRG1 Up-Regulation1
N. Huntington, H. Tabarias, K. Fairfax, J. Brady +5 more
2007Journal of Immunology348 citations Open access
Semantic Scholar
Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1.
A. Kallies, J. Hasbold, K. Fairfax, Clare Pridans +7 more
2007Immunity284 citations Open access
Semantic Scholar
FcγRIIb controls bone marrow plasma cell persistence and apoptosis
Z. Xiang, Antony J. Cutler, R. Brownlie, K. Fairfax +6 more
2007Nature Immunology282 citations
Semantic Scholar
Plasma cell development: from B-cell subsets to long-term survival niches.
K. Fairfax, A. Kallies, S. Nutt, D. Tarlinton
2008Seminars in Immunology228 citations
Semantic Scholar
FcgammaRIIb controls bone marrow plasma cell persistence and apoptosis.
Z. Xiang, Antony J. Cutler, R. Brownlie, K. Fairfax +6 more
2007Nature Immunology154 citations
Semantic Scholar
Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans
Jarny Choi, T. Baldwin, M. Wong, Jessica E. Bolden +15 more
2018Nucleic Acids Res.150 citations Open access
Semantic Scholar
BLIMP1 guides the fate of effector B and T cells
S. Nutt, K. Fairfax, A. Kallies
2007Nature reviews. Immunology146 citations
Semantic Scholar
The RNA-binding protein HuR (Elavl1) is essential for the B cell antibody response
Manuel D. Díaz-Muñoz, Sarah E. Bell, K. Fairfax, Elisa Monzón-Casanova +12 more
2015Nature Immunology103 citations Open access
Semantic Scholar
Different Kinetics of Blimp-1 Induction in B Cell Subsets Revealed by Reporter Gene1
K. Fairfax, L. Corcoran, Clare Pridans, N. Huntington +3 more
2007Journal of Immunology103 citations Open access
Semantic Scholar
Haemopedia: An Expression Atlas of Murine Hematopoietic Cells
C. D. de Graaf, Jarny Choi, T. Baldwin, Jessica E. Bolden +25 more
2016Stem Cell Reports95 citations Open access
Semantic Scholar
Assessing Immune-Related Adverse Events of Efficacious Combination Immunotherapies in Preclinical Models of Cancer.
Jing Liu, Stephen J. Blake, Heidi Harjunpää, K. Fairfax +6 more
2016Cancer Research87 citations Open access
Semantic Scholar
The TACI receptor regulates T-cell-independent marginal zone B cell responses through innate activation-induced cell death.
William A. Figgett, K. Fairfax, F. Vincent, M. Le Page +10 more
2013Immunity76 citations Open access
Semantic Scholar
Transitioning single-cell genomics into the clinic
Jennifer Lim, Venessa T. Chin, K. Fairfax, C. Moutinho +3 more
2023Nature reviews genetics72 citations
Semantic Scholar
Signaling Pathways in T Follicular Helper Cells
J. Rolf, K. Fairfax, M. Turner
2010Journal of Immunology50 citations Open access
Semantic Scholar
University of Birmingham The RNA-binding protein HuR is essential for the B cell antibody response
Manuel D. Díaz-Muñoz, Sarah E. Bell, K. Fairfax, Elisa Monzón-Casanova +14 more
201649 citations
Semantic Scholar
Deleting the BAFF receptor TACI protects against systemic lupus erythematosus without extensive reduction of B cell numbers.
William A. Figgett, Devy Deliyanti, K. Fairfax, Pin Shie Quah +2 more
2015Journal of Autoimmunity47 citations Open access
Semantic Scholar
BAFF/BLyS inhibitors: A new prospect for treatment of systemic lupus erythematosus
K. Fairfax, I. Mackay, F. Mackay
2012IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology46 citations Open access
Semantic Scholar
Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia.
M. Ghisi, L. Kats, F. Masson, Jason Li +15 more
2016Cancer Cell34 citations Open access
Semantic Scholar
NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells
Elisha de Valle, G. Grigoriadis, L. O'Reilly, S. Willis +16 more
2016Journal of Experimental Medicine34 citations Open access
Semantic Scholar
BAFF-driven autoimmunity requires CD19 expression.
K. Fairfax, E. Tsantikos, William A. Figgett, F. Vincent +4 more
2015Journal of Autoimmunity30 citations Open access
Semantic Scholar
The tyrosine kinase Lyn limits the cytokine responsiveness of plasma cells to restrict their accumulation in mice
S. Infantino, Sarah A. Jones, Jennifer A. Walker, M. Maxwell +10 more
2014Science Signaling28 citations Open access
Semantic Scholar
A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics
D. Amann-Zalcenstein, L. Tian, J. Schreuder, S. Tomei +17 more
2020Nature Immunology27 citations Open access
Semantic Scholar
CD19 differentially regulates BCR signalling through the recruitment of PI3K
Yuekang Xu, K. Fairfax, A. Light, N. Huntington +1 more
2014Autoimmunity25 citations Open access
Semantic Scholar
IL‐10 regulates Aicda expression through miR‐155
K. Fairfax, M. Gantier, F. Mackay, Bryan R. G. Williams +1 more
2015Journal of Leukocyte Biology24 citations
Semantic Scholar
Transcriptional profiling of eosinophil subsets in interleukin‐5 transgenic mice
K. Fairfax, Jessica E. Bolden, A. Robinson, Erin C. Lucas +5 more
2018Journal of Leukocyte Biology11 citations Open access
Semantic Scholar
Functional genomics for curation of variants in telomere biology disorder associated genes, a systematic review.
N. Nelson, Simone K Feurstein, A. Niaz, J. Truong +5 more
2022medRxiv10 citations Open access
Semantic Scholar
Absence of pro-survival A1 has no impact on inflammatory cell survival in vivo during acute lung inflammation and peritonitis
L. Gangoda, Robyn L. Schenk, S. Best, Christina Nedeva +8 more
2021Cell Death and Differentiation8 citations Open access
Semantic Scholar
Identification of a Siglec-F+ granulocyte-macrophage progenitor
Jessica E. Bolden, Erin C. Lucas, Geyu Zhou, Jeremy A. O'Sullivan +10 more
2018Journal of Leukocyte Biology8 citations Open access
Semantic Scholar
Gene Therapy Delivery of Myelin Oligodendrocyte Glycoprotein (MOG) via Hematopoietic Stem Cell Transfer Induces MOG-Specific B Cell Deletion
J. Chung, William A. Figgett, K. Fairfax, C. Bernard +4 more
2014Journal of Immunology8 citations Open access
Semantic Scholar
The effects of B‐cell–activating factor on the population size, maturation and function of murine natural killer cells
Pin Shie Quah, V. Sutton, Eden Whitlock, William A. Figgett +3 more
2022Immunology and Cell Biology6 citations Open access
Semantic Scholar
A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics
D. Amann-Zalcenstein, L. Tian, J. Schreuder, S. Tomei +17 more
2020Nature Immunology4 citations Open access
Semantic Scholar
Targeting malignant B cells as antigen-presenting cells: TLR-9 agonist induces systemic regression of lymphoma
N. Klein-González, U. Holtick, K. Fairfax, M. R. Weihrauch +1 more
2011Expert Review of Vaccines4 citations
Semantic Scholar
Mcl-1 is essential for the survival of plasma cells
V. Peperzak, I. Vikström, Jennifer A. Walker, Stefan P. Glaser +8 more
2013Nature Immunology2 citations Open access
Semantic Scholar
Fancl-mutant mice reveal central role of monoubiquitination in Fanconi anemia and a model for therapeutic gene editing
Lu Liu, Astrid Glaser, Abdulsalam I. Isiaku, K. Fairfax +16 more
2025Blood Advances0 citations Open access
Semantic Scholar
The performance of in silico prediction tools for variant curation in a panel of cancer genes.
N. Nelson, A. Niaz, K. Fairfax, T. Bryan +2 more
2025medRxiv0 citations Open access
Semantic Scholar
The role of BAFF in the biology of NK cells
P. Quah, K. Fairfax, D. Andrews, F. Mackay
20190 citations
Semantic Scholar
Fluorescent antibiotics, vomocytosis, vaccine candidates and the inflammasome
R. Lundie, K. Helbig, Jaclyn S. Pearson, K. Fairfax
2019Clinical & Translational Immunology0 citations Open access
Semantic Scholar
2037 – DACH1 DOWNREGULATION MARKS A ‘LYMPHOID-PRIMED PROGENITOR’ IN EARLY HAEMATOPOIESIS
S. Naik, Daniela Zalcenstein, L. Tian, J. Schreuder +14 more
2019Experimental Hematology0 citations Open access
Semantic Scholar
Abstract P2-12-18: Outpatient mastectomy with reconstruction in a freestanding surgery center using multimodality opiod-sparing perioperative analgesia including liposomal bupivacaine
D. Rock, Al Jandik, W. Wittenborn, K. Fairfax +1 more
20160 citations
Semantic Scholar
Abstract B122: A preclinical mouse model to assess antitumor efficacy and development of immune related adverse events (irAEs) following combination immunotherapies
Jing Liu, Stephten J. Blake, K. Fairfax, M. Yong +3 more
20160 citations
Semantic Scholar
MOG-Specific B Cell Deletion Hematopoietic Stem Cell Transfer Induces Oligodendrocyte Glycoprotein (MOG) via Gene Therapy Delivery of Myelin
J. Chung, William A. Figgett, K. Fairfax, C. Bernard +4 more
20140 citations
Semantic Scholar
65: Nuclear Factor-kappa B1 is a critical regulator of mature B cell homeostasis and serves to prevent chronic inflammatory disease
Elisha de Valle, G. Grigoriadis, L. O'Reilly, S. Willis +4 more
20140 citations
Semantic Scholar
Lyn limits cytokine responsiveness of plasma cells to restrict their accumulation.
K. Fairfax, S. Infantino, Sarah A. Jones, M. Hibbs +1 more
20140 citations Open access
Semantic Scholar
179: MIRNA analysis reveals novel insights into IL10 function
C. McCoy, S. Quinn, M. Gantier, K. Fairfax +2 more
20130 citations
Semantic Scholar
Up-RegulationIs Associated with KLRG1 NK Cell Maturation and Peripheral
M. Smyth, D. Tarlinton, Y. Hayakawa, M. Degli-Esposti +3 more
20130 citations
Semantic Scholar
Plasma cell differentiation (WS-050) Chairpersons: Takeshi Tokuhisa, Stephen Nutt
E. Mohr, A. Cunningham, K. Toellner, R. Manz +46 more
20100 citations
Semantic Scholar
This information is current as Up-Regulation Homeostasis Is Associated with KLRG 1 NK Cell Maturation and Peripheral
Nicholas D. Huntington, H. Tabarias, K. Fairfax, J. Brady +5 more
20070 citations
Semantic Scholar

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William A. Figgett

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