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R. N. Harty · SciRah

Researcher profile · Semantic Scholar

R. N. Harty

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R. N. Harty — researcher profile on SciRah

h-index: 40
Works: 94
Citations: 5,086

Most-cited papers

A PPxY motif within the VP40 protein of Ebola virus interacts physically and functionally with a ubiquitin ligase: implications for filovirus budding.
R. N. Harty, Melissa E. Brown, Guang-Li Wang, J. Huibregtse +1 more
2000Proceedings of the National Academy of Sciences of the United States of America481 citations Open access
Semantic Scholar
ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity
A. Okumura, P. Pitha, R. N. Harty
2008Proceedings of the National Academy of Sciences of the United States of America308 citations Open access
Semantic Scholar
A Proline-Rich Motif within the Matrix Protein of Vesicular Stomatitis Virus and Rabies Virus Interacts with WW Domains of Cellular Proteins: Implications for Viral Budding
R. N. Harty, Jason Paragas, M. Sudol, P. Palese
1999Journal of Virology303 citations Open access
Semantic Scholar
Overlapping Motifs (PTAP and PPEY) within the Ebola Virus VP40 Protein Function Independently as Late Budding Domains: Involvement of Host Proteins TSG101 and VPS-4
Jillian M. Licata, M. Simpson-Holley, N. Wright, Zi-Ying Han +2 more
2003Journal of Virology285 citations Open access
Semantic Scholar
Contribution of Ebola Virus Glycoprotein, Nucleoprotein, and VP24 to Budding of VP40 Virus-Like Particles
Jillian M. Licata, Reed F. Johnson, Zi-Ying Han, R. N. Harty
2004Journal of Virology243 citations Open access
Semantic Scholar
Rhabdoviruses and the Cellular Ubiquitin-Proteasome System: a Budding Interaction
R. N. Harty, Melissa E. Brown, J. McGettigan, Guang-Li Wang +4 more
2001Journal of Virology214 citations Open access
Semantic Scholar
Interaction between Ebola Virus Glycoprotein and Host Toll-Like Receptor 4 Leads to Induction of Proinflammatory Cytokines and SOCS1
A. Okumura, P. Pitha, A. Yoshimura, R. N. Harty
2009Journal of Virology171 citations Open access
Semantic Scholar
Late Domain Function Identified in the Vesicular Stomatitis Virus M Protein by Use of Rhabdovirus-Retrovirus Chimeras
R. Craven, R. N. Harty, Jason Paragas, P. Palese +1 more
1999Journal of Virology149 citations Open access
Semantic Scholar
Biochemical and Functional Characterization of the Ebola Virus VP24 Protein: Implications for a Role in Virus Assembly and Budding
Zi-Ying Han, H. Boshra, J. Sunyer, S. Zwiers +2 more
2003Journal of Virology136 citations Open access
Semantic Scholar
Phospholipid Scramblase 1 Potentiates the Antiviral Activity of Interferon
Bei-Hua Dong, Quan-Sheng Zhou, Ji Zhao, Ai-Min Zhou +9 more
2004Journal of Virology123 citations Open access
Semantic Scholar
Antiviral Activity of Innate Immune Protein ISG15
R. N. Harty, P. Pitha, A. Okumura
2009Journal of Innate Immunity108 citations Open access
Semantic Scholar
The NS3 Protein of Bluetongue Virus Exhibits Viroporin-like Properties*
Zi-Ying Han, R. N. Harty
2004Journal of Biological Chemistry108 citations Open access
Semantic Scholar
Budding of PPxY-Containing Rhabdoviruses Is Not Dependent on Host Proteins TGS101 and VPS4A
T. Irie, Jillian M. Licata, J. McGettigan, M. Schnell +1 more
2004Journal of Virology104 citations Open access
Semantic Scholar
Small-Molecule Probes Targeting the Viral PPxY-Host Nedd4 Interface Block Egress of a Broad Range of RNA Viruses
Zi-Ying Han, Jian-Hong Lu, Yuliang Liu, Benjamin M. Davis +8 more
2014Journal of Virology102 citations Open access
Semantic Scholar
Measles virus phosphoprotein (P) requires the NH2- and COOH-terminal domains for interactions with the nucleoprotein (N) but only the COOH terminus for interactions with itself.
R. N. Harty, P. Palese
1995Journal of General Virology93 citations Open access
Semantic Scholar
PPEY Motif within the Rabies Virus (RV) Matrix Protein Is Essential for Efficient Virion Release and RV Pathogenicity
C. Wirblich, G. Tan, Amy B. Papaneri, Peter J Godlewski +3 more
2008Journal of Virology86 citations Open access
Semantic Scholar
Effect of Ebola virus proteins GP, NP and VP35 on VP40 VLP morphology
Reed F. Johnson, Peter Bell, R. N. Harty
2006Virology Journal82 citations Open access
Semantic Scholar
Evaluation of an Attenuated Vesicular Stomatitis Virus Vector Expressing Interferon-β for Use in Malignant Pleural Mesothelioma: Heterogeneity in Interferon Responsiveness Defines Potential Efficacy
V. Saloura, Liang-Chuan S. Wang, Z. Fridlender, Jing Sun +11 more
2010Human Gene Therapy77 citations Open access
Semantic Scholar
Host IQGAP1 and Ebola Virus VP40 Interactions Facilitate Virus-Like Particle Egress
Jian-Hong Lu, Yonggang Qu, Yuliang Liu, R. Jambusaria +4 more
2013Journal of Virology73 citations Open access
Semantic Scholar
Ebola Virus VP35-VP40 Interaction Is Sufficient for Packaging 3E-5E Minigenome RNA into Virus-Like Particles
Reed F. Johnson, Sarah E. McCarthy, Peter J Godlewski, R. N. Harty
2006Journal of Virology72 citations
Semantic Scholar
The YPLGVG sequence of the Nipah virus matrix protein is required for budding
J. Patch, Zi-Ying Han, Sarah E. McCarthy, Lian-Ying Yan +3 more
2008Virology Journal70 citations Open access
Semantic Scholar
No exit: targeting the budding process to inhibit filovirus replication
R. N. Harty
2008Antiviral Research70 citations Open access
Semantic Scholar
The multifunctional Ebola virus VP40 matrix protein is a promising therapeutic target
Jonathan J. Madara, Zi-Ying Han, G. Ruthel, Bruce D. Freedman +1 more
2015Future Virology63 citations Open access
Semantic Scholar
Conserved Motifs within Ebola and Marburg Virus VP40 Proteins Are Important for Stability, Localization, and Subsequent Budding of Virus-Like Particles
Yuliang Liu, L. Cocka, A. Okumura, Yong'an Zhang +2 more
2009Journal of Virology61 citations Open access
Semantic Scholar
ALIX Rescues Budding of a Double PTAP/PPEY L-Domain Deletion Mutant of Ebola VP40: A Role for ALIX in Ebola Virus Egress.
Zi-Ying Han, Jonathan J. Madara, Yuliang Liu, Wen-Bo Liu +3 more
2015Journal of Infectious Diseases60 citations Open access
Semantic Scholar
Chimeric animal and plant viruses expressing epitopes of outer membrane protein F as a combined vaccine against Pseudomonas aeruginosa lung infection.
H. E. Gilleland, Linda B. Gilleland, J. Staczek, R. N. Harty +6 more
2000FEMS Immunology & Medical Microbiology60 citations
Semantic Scholar
ITCH E3 Ubiquitin Ligase Interacts with Ebola Virus VP40 To Regulate Budding
Zi-Ying Han, Cari A. Sagum, M. Bedford, S. Sidhu +2 more
2016Journal of Virology58 citations Open access
Semantic Scholar
Packaging of actin into Ebola virus VLPs
Zi-Ying Han, R. N. Harty
2005Virology Journal55 citations Open access
Semantic Scholar
Functional characterization of Ebola virus L-domains using VSV recombinants.
T. Irie, Jillian M. Licata, R. N. Harty
2005Virology55 citations Open access
Semantic Scholar
SARS-CoV-2 Envelope (E) protein interacts with PDZ-domain-2 of host tight junction protein ZO1
Ariel Shepley-McTaggart, Cari A. Sagum, I. Oliva, E. Rybakovsky +7 more
2021PLoS ONE54 citations Open access
Semantic Scholar
Debulking SARS-CoV-2 in saliva using angiotensin converting enzyme 2 in chewing gum to decrease oral virus transmission and infection
H. Daniell, Smruti K Nair, N. Esmaeili, G. Wakade +22 more
2021Molecular Therapy53 citations Open access
Semantic Scholar
Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress
Jing-Jing Liang, Cari A. Sagum, M. Bedford, S. Sidhu +3 more
2017PLoS Pathogens51 citations Open access
Semantic Scholar
Calcium Regulation of Hemorrhagic Fever Virus Budding: Mechanistic Implications for Host-Oriented Therapeutic Intervention
Zi-Ying Han, Jonathan J. Madara, A. Herbert, Laura I. Prugar +10 more
2015PLoS Pathogens50 citations Open access
Semantic Scholar
Quinoxaline-based inhibitors of Ebola and Marburg VP40 egress
H. M. Loughran, Zi-Ying Han, J. Wrobel, Sarah E Decker +4 more
2016Bioorganic & Medicinal Chemistry Letters49 citations Open access
Semantic Scholar
Functional Analysis of Late-Budding Domain Activity Associated with the PSAP Motif within the Vesicular Stomatitis Virus M Protein
T. Irie, Jillian M. Licata, H. R. Jayakar, M. Whitt +2 more
2004Journal of Virology48 citations Open access
Semantic Scholar
Role for Amino Acids 212KLR214 of Ebola Virus VP40 in Assembly and Budding
Sarah E. McCarthy, Reed F. Johnson, Yong'an Zhang, J. Sunyer +1 more
2007Journal of Virology47 citations Open access
Semantic Scholar
A Host-Oriented Inhibitor of Junin Argentine Hemorrhagic Fever Virus Egress
Jian-Hong Lu, Zi-Ying Han, Yuliang Liu, Wen-Bo Liu +5 more
2014Journal of Virology44 citations Open access
Semantic Scholar
A Chimeric Influenza Virus Expressing an Epitope of Outer Membrane Protein F of Pseudomonas aeruginosa Affords Protection against Challenge with P. aeruginosa in a Murine Model of Chronic Pulmonary Infection
J. Staczek, H. E. Gilleland, Linda B. Gilleland, R. N. Harty +3 more
1998Infection and Immunity44 citations Open access
Semantic Scholar
Rabies virus assembly and budding.
A. Okumura, R. N. Harty
2011Advances in Virus Research42 citations
Semantic Scholar
Ubiquitin Ligase WWP1 Interacts with Ebola Virus VP40 To Regulate Egress
Zi-Ying Han, Cari A. Sagum, Fumio Takizawa, G. Ruthel +8 more
2017Journal of Virology40 citations Open access
Semantic Scholar
Vaccinia virus-free recovery of vesicular stomatitis virus.
R. N. Harty, Melissa E. Brown, Felicia P. Hayes, Nathan T. Wright +1 more
2001Journal of Molecular Microbiology and Biotechnology40 citations
Semantic Scholar
Viral and host proteins that modulate filovirus budding
Yuliang Liu, R. N. Harty
2010Future Virology39 citations Open access
Semantic Scholar
RHABDOVIRUSES AND APOPTOSIS
Jillian M. Licata, R. N. Harty
2003International Reviews of Immunology37 citations
Semantic Scholar
Bimolecular Complementation to Visualize Filovirus VP40-Host Complexes in Live Mammalian Cells: Toward the Identification of Budding Inhibitors
Yuliang Liu, Michael S. Lee, M. A. Olson, R. N. Harty
2011Advances in Virology36 citations Open access
Semantic Scholar
WW- and SH3-domain interactions with Epstein-Barr virus LMP2A.
R. Longnecker, Mark Merchant, Melissa E. Brown, Sara Fruehling +3 more
2000Experimental Cell Research36 citations
Semantic Scholar
Suppressor of Cytokine Signaling 3 Is an Inducible Host Factor That Regulates Virus Egress during Ebola Virus Infection
A. Okumura, A. Rasmussen, Peter J. Halfmann, F. Feldmann +5 more
2015Journal of Virology33 citations Open access
Semantic Scholar
Detection and intracellular localization of equine herpesvirus 1 IR1 and IR2 gene products by using monoclonal antibodies
G. Caughman, Jill Lewis, Richard H. Smith, R. N. Harty +1 more
1995Journal of Virology32 citations Open access
Semantic Scholar
SARS-CoV-2 Envelope (E) Protein Interacts with PDZ-Domain-2 of Host Tight Junction Protein ZO1
Ariel Shepley-McTaggart, Cari A. Sagum, I. Oliva, E. Rybakovsky +7 more
2020bioRxiv30 citations Open access
Semantic Scholar
Influence of calcium/calmodulin on budding of Ebola VLPs: implications for the involvement of the Ras/Raf/MEK/ERK pathway
Zi-Ying Han, R. N. Harty
2007Virus genes29 citations
Semantic Scholar
L-Domain Flanking Sequences Are Important for Host Interactions and Efficient Budding of Vesicular Stomatitis Virus Recombinants
T. Irie, R. N. Harty
2005Journal of Virology28 citations Open access
Semantic Scholar

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