M. Helleberg

Most-cited papers

1. Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial.

   M. W. Munch, S. Myatra, B. Vijayaraghavan, S. Saseedharan +75 more

   2021Journal of the American Medical Association (JAMA)238 citations Open access

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2. Persistent COVID-19 in an Immunocompromised Patient Temporarily Responsive to Two Courses of Remdesivir Therapy

   M. Helleberg, C. Niemann, K. Moestrup, O. Kirk +3 more

   2020Journal of Infectious Diseases163 citations Open access

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3. Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial

   Wesley H. Uriel Cavan S. David M. Robert L. Michael Kevin Self Sandkovsky Reilly Vock Gottlieb Mack Golden D, W. Self, U. Sandkovsky, Cavan Reilly +496 more

   2021Lancet. Infectious Diseases (Print)156 citations Open access

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4. Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia: a pre-planned, secondary Bayesian analysis of the COVID STEROID 2 trial

   A. Granholm, M. W. Munch, S. Myatra, B. Vijayaraghavan +42 more

   2021Intensive Care Medicine114 citations Open access

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5. Characteristics, interventions, and longer term outcomes of COVID‐19 ICU patients in Denmark—A nationwide, observational study

   N. Haase, R. Plovsing, S. Christensen, L. Poulsen +26 more

   2020Acta Anaesthesiologica Scandinavica84 citations Open access

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6. Developing and validating COVID-19 adverse outcome risk prediction models from a bi-national European cohort of 5594 patients

   E. Jimenez-Solem, T. Petersen, Casper Hansen, Christian Hansen +31 more

   2020Scientific Reports71 citations Open access

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7. Improved Survival Among Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Treated With Remdesivir and Dexamethasone. A Nationwide Population-Based Cohort Study

   T. Benfield, J. Bodilsen, Christian Brieghel, Z. Harboe +27 more

   2021Clinical Infectious Diseases68 citations Open access

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8. Hyperimmune immunoglobulin for hospitalised patients with COVID-19 (ITAC): a double-blind, placebo-controlled, phase 3, randomised trial

   M. Polizzotto, J. Nordwall, A. Babiker, A. Phillips +84 more

   2022The Lancet65 citations Open access

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9. Associations of the gut microbiome and clinical factors with acute GVHD in allogeneic HSCT recipients.

   E. Ilett, M. Jørgensen, M. Noguera-Julián, J. C. Nørgaard +8 more

   2020Blood Advances63 citations Open access

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10. Invasive aspergillosis in patients with severe COVID-19 pneumonia

    M. Helleberg, M. Steensen, M. Arendrup

    2020Clinical Microbiology and Infection61 citations Open access

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11. Patients with CLL have a lower risk of death from COVID-19 in the Omicron era

    C. Niemann, C. da Cunha-Bang, M. Helleberg, S. Ostrowski +1 more

    2022Blood60 citations Open access

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12. Diagnostic Performance of T2Candida Among ICU Patients With Risk Factors for Invasive Candidiasis

    M. Arendrup, J. S. Andersen, Mads Kristian Holten, K. B. Krarup +3 more

    2019Open Forum Infectious Diseases56 citations Open access

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13. Hematological toxicity in patients with solid malignant tumors treated with radiation - temporal analysis, dose response and impact on survival.

    C. Terrones-Campos, B. Ledergerber, I. Vogelius, M. Helleberg +2 more

    2021Radiotherapy and Oncology54 citations

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14. Therapeutic Drug Monitoring of Isavuconazole: Serum Concentration Variability and Success Rates for Reaching Target in Comparison with Voriconazole

    Malene Risum, Mai-Britt Vestergaard, U. Weinreich, M. Helleberg +2 more

    2021Antibiotics52 citations Open access

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15. Rezafungin In Vitro Activity against Contemporary Nordic Clinical Candida Isolates and Candida auris Determined by the EUCAST Reference Method

    M. Helleberg, K. M. Jørgensen, R. Hare, R. Datcu +2 more

    2020Antimicrobial Agents and Chemotherapy51 citations Open access

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16. Incidence and predictors of infection among patients prior to treatment of chronic lymphocytic leukemia: a Danish nationwide cohort study

    M. A. Andersen, Casper T. Eriksen, C. Brieghel, J. Biccler +3 more

    2018Haematologica45 citations Open access

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17. Low‐dose hydrocortisone in patients with COVID‐19 and severe hypoxia: The COVID STEROID randomised, placebo‐controlled trial

    M. W. Munch, T. Meyhoff, M. Helleberg, M. N. Kjær +68 more

    2021Acta Anaesthesiologica Scandinavica41 citations Open access

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18. Mutations in LC3B2 and ATG4A underlie recurrent HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans

    A. Hait, D. Olagnier, V. Sancho-Shimizu, K. A. Skipper +22 more

    2020Science immunology41 citations Open access

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19. Mortality and admission to intensive care units after febrile neutropenia in patients with cancer

    Theis Aagaard, J. Reekie, M. Jørgensen, A. Roen +6 more

    2020Cancer Medicine39 citations Open access

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20. Lymphocyte Count Kinetics, Factors Associated with the End of Radiotherapy Lymphocyte Count and Risk of Infection in Patients with Solid Malignant Tumors treated with Curative Intent Radiotherapy.

    C. Terrones-Campos, B. Ledergerber, I. Vogelius, L. Specht +2 more

    2019International Journal of Radiation Oncology, Biology, Physics39 citations

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21. Whole Exome Sequencing of HIV-1 long-term non-progressors identifies rare variants in genes encoding innate immune sensors and signaling molecules

    S. K. Nissen, M. Christiansen, M. Helleberg, K. Kjær +11 more

    2018Scientific Reports37 citations Open access

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22. Gut microbiome comparability of fresh-frozen versus stabilized-frozen samples from hospitalized patients using 16S rRNA gene and shotgun metagenomic sequencing

    E. Ilett, M. Jørgensen, M. Noguera-Julián, G. Daugaard +6 more

    2019Scientific Reports35 citations Open access

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23. Febrile Neutropenia and Long-term Risk of Infection Among Patients Treated With Chemotherapy for Malignant Diseases

    Josefine Nordvig, Theis Aagaard, G. Daugaard, P. Brown +3 more

    2018Open Forum Infectious Diseases33 citations Open access

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24. Determinants of Restoration of CD4 and CD8 Cell Counts and Their Ratio in HIV-1–Positive Individuals With Sustained Virological Suppression on Antiretroviral Therapy

    L. Gras, M. May, L. Ryder, A. Trickey +27 more

    2018Journal of Acquired Immune Deficiency Syndromes33 citations Open access

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25. Risk of Bacterial, Viral, and Fungal Infections in Patients With Solid Malignant Tumors Treated With Curative Intent Radiation Therapy

    C. Terrones-Campos, B. Ledergerber, L. Specht, I. Vogelius +2 more

    2022Advances in Radiation Oncology30 citations Open access

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26. Long-term outcomes of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia

    A. Granholm, M. N. Kjær, M. W. Munch, S. Myatra +45 more

    2022Intensive Care Medicine30 citations Open access

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27. A Large-Cohort, Longitudinal Study Determines Precancer Disease Routes across Different Cancer Types.

    J. X. Hu, M. Helleberg, A. B. Jensen, S. Brunak +1 more

    2019Cancer Research30 citations Open access

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28. Richter’s transformation in patients with chronic lymphocytic leukaemia: a Nationwide Epidemiological Study

    Yasmin Ben-Dali, M. H. Hleuhel, C. da Cunha-Bang, C. Brieghel +13 more

    2020Leukemia and Lymphoma28 citations

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29. Low‐dose hydrocortisone in patients with COVID‐19 and severe hypoxia (COVID STEROID) trial—Protocol and statistical analysis plan

    Marie Warrer Petersen, T. Meyhoff, M. Helleberg, M. N. Kjær +37 more

    2020Acta Anaesthesiologica Scandinavica27 citations Open access

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30. Higher vs lower doses of dexamethasone in patients with COVID‐19 and severe hypoxia (COVID STEROID 2) trial: Protocol and statistical analysis plan

    M. W. Munch, A. Granholm, S. Myatra, B. Vijayaraghavan +41 more

    2021Acta Anaesthesiologica Scandinavica26 citations Open access

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31. Evaluation of an electronic, patient‐focused management system aimed at preventing cytomegalovirus disease following solid organ transplantation

    C. Ekenberg, Caspar Cunha-Bang, I. Lodding, S. Sørensen +10 more

    2020Transplant Infectious Disease25 citations

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32. 82. Incidence rates of invasive aspergillosis among lung transplant recipients in timeperiods with universal and targeted antifungal prophylaxis - a nationwide cohort study

    C. G. Crone, S. M. Wulff, B. Ledergerber, P. Bredahl +4 more

    2022Open Forum Infectious Diseases23 citations Open access

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33. Risk factors during pregnancy and birth‐related complications in HIV‐positive versus HIV‐negative women in Denmark, 2002–2014

    M. Ørbæk, K. Thorsteinsson, E. Larsen, T. Katzenstein +7 more

    2020HIV Medicine23 citations Open access

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34. Prediction of Radiation-induced Lymphopenia following Exposure of the Thoracic Region and Associated Risk of Infections and Mortality.

    C. Terrones-Campos, B. Ledergerber, N. Forbes, A. Smith +5 more

    2023Clinics in oncology20 citations Open access

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35. Dissection of the Activity of Agricultural Fungicides against Clinical Aspergillus Isolates with and without Environmentally and Medically Induced Azole Resistance

    K. M. Jørgensen, M. Helleberg, R. Hare, L. N. Jørgensen +1 more

    2021Journal of Fungi20 citations Open access

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36. SARS‐CoV‐2 infection among patients with haematological disorders: Severity and one‐month outcome in 66 Danish patients in a nationwide cohort study

    A. Glenthøj, L. Jakobsen, H. Sengeløv, S. Ahmad +20 more

    2020European Journal of Haematology20 citations Open access

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37. Incidence Rates and Risk Factors of Clostridioides difficile Infection in Solid Organ and Hematopoietic Stem Cell Transplant Recipients

    E. Ilett, M. Helleberg, J. Reekie, Daniel D. Murray +11 more

    2019Open Forum Infectious Diseases20 citations Open access

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38. Changes over time in characteristics, resource use and outcomes among ICU patients with COVID‐19—A nationwide, observational study in Denmark

    N. Haase, R. Plovsing, S. Christensen, L. Poulsen +35 more

    2022Acta Anaesthesiologica Scandinavica18 citations Open access

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39. Early stimulated immune responses predict clinical disease severity in hospitalized COVID-19 patients

    R. Svanberg, C. MacPherson, Adrian G. Zucco, R. Agius +22 more

    2022Communications Medicine18 citations Open access

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40. Children exposed or unexposed to HIV: weight, height and BMI during the first five years of life. A Danish Nationwide Cohort Study.

    E. Moseholm, M. Helleberg, Håkon Sandholdt, T. Katzenstein +4 more

    2019Clinical Infectious Diseases18 citations Open access

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41. Added Value of Reanalysis of Whole Exome- and Whole Genome Sequencing Data From Patients Suspected of Primary Immune Deficiency Using an Extended Gene Panel and Structural Variation Calling

    Sara Mørup, Lusine Nazaryan-Petersen, Miglė Gabrielaitė, J. Reekie +9 more

    2022Frontiers in Immunology17 citations Open access

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42. Genetic variants and immune responses in a cohort of patients with varicella zoster virus encephalitis.

    Michelle M. Thomsen, T. Tyrberg, Kristoffer Skaalum, Madalina E. Carter-Timofte +8 more

    2021Journal of Infectious Diseases17 citations

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43. Development and validation of a cycle‐specific risk score for febrile neutropenia during chemotherapy cycles 2–6 in patients with solid cancers: The CSRFENCE score

    Theis Aagaard, J. Reekie, A. Roen, G. Daugaard +5 more

    2019International Journal of Cancer16 citations Open access

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44. Whole Exome Sequencing of patients with recurrent HSV-2 lymphocytic Mollaret's meningitis.

    A. Hait, Michelle M. Thomsen, S. M. Larsen, M. Helleberg +5 more

    2020Journal of Infectious Diseases15 citations

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45. Single nucleotide polymorphisms in HLA alleles are associated with HIV-1 viral load in demographically diverse, ART-naïve participants from the START trial.

    C. Ekenberg, M. Tang, Adrian G. Zucco, Daniel D. Murray +15 more

    2019Journal of Infectious Diseases13 citations Open access

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46. Association Between Single-Nucleotide Polymorphisms in HLA Alleles and Human Immunodeficiency Virus Type 1 Viral Load in Demographically Diverse, Antiretroviral Therapy–Naive Participants From the Strategic Timing of AntiRetroviral Treatment Trial

    C. Ekenberg, M. Tang, Adrian G. Zucco, Daniel D. Murray +15 more

    2019Journal of Infectious Diseases13 citations Open access

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47. Chest x-ray imaging score is associated with severity of COVID-19 pneumonia: the MBrixia score

    Christian M. Jensen, Junia C Costa, J. C. Nørgaard, Adrian G. Zucco +10 more

    2022Scientific Reports12 citations Open access

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48. Higher vs Lower Doses of Dexamethasone in Patients with COVID‐19 and Severe Hypoxia (COVID STEROID 2) trial: Protocol for a secondary Bayesian analysis

    A. Granholm, M. W. Munch, S. Myatra, B. Vijayaraghavan +41 more

    2021Acta Anaesthesiologica Scandinavica12 citations Open access

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49. Pulmonary mucormycosis in the aftermath of critical COVID-19 in an immunocompromised patient: Mind the diagnostic gap

    C. G. Crone, J. Helweg-Larsen, M. Steensen, M. Arendrup +1 more

    2021Journal de Mycologie Médicale12 citations Open access

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50. Bacillary angiomatosis in a solid organ transplant recipient

    J. F. Schwensen, Regitze Henrik Nielsen, M. Helleberg

    2019IDCases12 citations Open access

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