Researcher profile · Semantic Scholar

Manal A. Farg

h-index: 18
Works: 28
Citations: 2,562

Most-cited papers

Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis.
J. Atkin, Manal A. Farg, A. Walker, C. Mclean +2 more
2008Neurobiology of Disease349 citations Open access
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C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking
Manal A. Farg, V. Sundaramoorthy, J. Sultana, Shu Yang +8 more
2014Human Molecular Genetics309 citations Open access
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C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking
Manal A. Farg, V. Sundaramoorthy, J. Sultana, Shu Yang +8 more
2017Human Molecular Genetics265 citations Open access
Semantic Scholar
Impaired Extracellular Secretion of Mutant Superoxide Dismutase 1 Associates with Neurotoxicity in Familial Amyotrophic Lateral Sclerosis
B. J. Turner, J. Atkin, Manal A. Farg, D. Zang +5 more
2005Journal of Neuroscience209 citations Open access
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ALS-Associated TDP-43 Induces Endoplasmic Reticulum Stress, Which Drives Cytoplasmic TDP-43 Accumulation and Stress Granule Formation
A. Walker, Kai Y. Soo, V. Sundaramoorthy, S. Parakh +7 more
2013PLoS ONE188 citations Open access
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Induction of the Unfolded Protein Response in Familial Amyotrophic Lateral Sclerosis and Association of Protein-disulfide Isomerase with Superoxide Dismutase 1*
J. Atkin, Manal A. Farg, B. J. Turner, D. Tomas +7 more
2006Journal of Biological Chemistry187 citations Open access
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Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis.
A. Walker, Manal A. Farg, C. Bye, C. Mclean +2 more
2010Brain : a journal of neurology175 citations
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The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis
Manal A. Farg, A. Konopka, Kai Y. Soo, D. Ito +1 more
2017Human Molecular Genetics154 citations Open access
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Rab1-dependent ER–Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS
Kai Y. Soo, Mark A. Halloran, V. Sundaramoorthy, S. Parakh +7 more
2015Acta Neuropathologica112 citations Open access
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Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis.
Manal A. Farg, Kai Y. Soo, S. T. Warraich, V. Sundaramoorthy +2 more
2013Human Molecular Genetics112 citations Open access
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Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase.
Manal A. Farg, Kai Y. Soo, A. Walker, Hong Pham +6 more
2012Neurobiology of Aging105 citations
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Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1.
J. Atkin, Manal A. Farg, B. J. Turner, D. Tomas +7 more
2006Journal of Biological Chemistry76 citations Open access
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Extracellular wildtype and mutant SOD1 induces ER–Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells
V. Sundaramoorthy, A. Walker, J. Yerbury, Kai Y. Soo +5 more
2013Cellular and Molecular Life Sciences74 citations Open access
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Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis.
V. Sundaramoorthy, A. Walker, V. Tan, Jennifer A. Fifita +6 more
2015Human Molecular Genetics65 citations
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ALS-associated mutant FUS inhibits macroautophagy which is restored by overexpression of Rab1
Kai Y. Soo, J. Sultana, A. King, Rachel A K Atkinson +5 more
2015Cell Death Discovery59 citations Open access
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Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis.
V. Sundaramoorthy, A. Walker, V. Tan, Jennifer A. Fifita +6 more
2017Human Molecular Genetics46 citations Open access
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Bim Links ER Stress and Apoptosis in Cells Expressing Mutant SOD1 Associated with Amyotrophic Lateral Sclerosis
Kai Y. Soo, J. Atkin, Manal A. Farg, A. Walker +2 more
2012PLoS ONE45 citations Open access
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Molecular Motor Proteins and Amyotrophic Lateral Sclerosis
Kai Y. Soo, Manal A. Farg, J. Atkin
2011International Journal of Molecular Sciences19 citations Open access
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SOD1 Mutations Causing Familial Amyotrophic Lateral Sclerosis Induce Toxicity in Astrocytes: Evidence for Bystander Effects in a Continuum of Astrogliosis
Nicole Wallis, Chew L. Lau, Manal A. Farg, J. Atkin +2 more
2017Neurochemical Research12 citations
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Erratum: Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis (Human molecular genetics (2015) 24 13 (3830-3846))
V. Sundaramoorthy, A. Walker, V. Tan, Jennifer A. Fifita +6 more
20176 citations Open access
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Corrigendum to: Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis.
Manal A. Farg, Kai Y. Soo, S. T. Warraich, V. Sundaramoorthy +2 more
2020Human Molecular Genetics1 citations Open access
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Retraction notice to "endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis": [neurobiology of disease, 30/3 (June 2008) 400-407].
J. Atkin, Manal A. Farg, A. Walker, C. Mclean +2 more
2020Neurobiology of Disease0 citations Open access
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SOD1 Mutations Causing Familial Amyotrophic Lateral Sclerosis Induce Toxicity in Astrocytes: Evidence for Bystander Effects in a Continuum of Astrogliosis
Nicole Wallis, Chew L. Lau, Manal A. Farg, J. Atkin +2 more
2018Neurochemical Research0 citations
Semantic Scholar
Wildtype TDP-43 functions in DNA repair but this process is perturbed in ALS
A. Konopka, Manal A. Farg, Shafi Jamali, J. Atkin
20180 citations
Semantic Scholar
Note in reference to “Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase” [Neurobiol. Aging 33(12) (2012) 2855-2868]
Manal A. Farg, Kai Y. Soo, A. Walker, Hong Pham +6 more
20170 citations
Semantic Scholar
PDI co-precipitates with TDP-43 and is increased in mutant TDP-43 transgenic mouse spinal cords.
A. Walker, Kai Y. Soo, V. Sundaramoorthy, S. Parakh +7 more
20130 citations Open access
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transport in Amyotrophic Lateral Sclerosis
J. Atkin, Manal A. Farg, Kai Y. Soo, A. Walker +4 more
20130 citations
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inhibits ER-Golgi transport in Amyotrophic Lateral Sclerosis
J. Atkin, Manal A. Farg, Kai Y. Soo, A. Walker +4 more
20130 citations
Semantic Scholar

V. Sundaramoorthy

×12

I. Blair×10

B. J. Turner×7

Mark A. Halloran×5

P. Nagley×5

S. T. Warraich×5

K. Williams×5

C. Mclean×4