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J. Castro · SciRah

Researcher profile · Semantic Scholar

J. Castro

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J. Castro — researcher profile on SciRah

h-index: 40
Works: 329
Citations: 11K

Most-cited papers

Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma
S. Neelapu, F. Locke, N. Bartlett, L. Lekakis +36 more
2017New England Journal of Medicine5,055 citations Open access
Semantic Scholar
Phase I Trial: Cirmtuzumab Inhibits ROR1 Signaling and Stemness Signatures in Patients with Chronic Lymphocytic Leukemia
M. Choi, G. Widhopf, E. Ghia, Reilly L. Kidwell +12 more
2018Cell Stem Cell176 citations Open access
Semantic Scholar
KTE-X19 anti-CD19 CAR T-cell therapy in adult relapsed/refractory acute lymphoblastic leukemia: ZUMA-3 phase 1 results.
B. Shah, M. Bishop, Olalekan O. Oluwole, A. Logan +23 more
2021Blood175 citations Open access
Semantic Scholar
Acute Lymphoblastic Leukemia, Version 2.2015.
J. Alvarnas, P. Brown, P. Aoun, K. Ballen +26 more
2015The Journal of the National Comprehensive Cancer Network111 citations Open access
Semantic Scholar
Clinical Practice Recommendations for Use of Allogeneic Hematopoietic Cell Transplantation in Chronic Lymphocytic Leukemia on Behalf of the Guidelines Committee of the American Society for Blood and Marrow Transplantation
M. Kharfan-Dabaja, Ambuj Kumar, M. Hamadani, S. Stilgenbauer +24 more
2016Biology of Blood and Marrow Transplantation98 citations Open access
Semantic Scholar
Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway
M. Kashyap, Deepak Kumar, H. Jones, C. Amaya-Chanaga +11 more
2015OncoTarget91 citations Open access
Semantic Scholar
Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B
M. Kashyap, Deepak Kumar, Reymundo Villa, J. L. La Clair +8 more
2015Haematologica86 citations Open access
Semantic Scholar
Lenalidomide and rituximab for the initial treatment of patients with chronic lymphocytic leukemia: a multicenter clinical-translational study from the chronic lymphocytic leukemia research consortium.
D. James, L. Werner, Jennifer R. Brown, W. Wierda +8 more
2014Journal of Clinical Oncology72 citations Open access
Semantic Scholar
Targeting the CXCR4 Pathway: Safety, Tolerability and Clinical Activity of Ulocuplumab (BMS-936564), an Anti-CXCR4 Antibody, in Relapsed/Refractory Acute Myeloid Leukemia
P. Becker, J. Foran, J. Altman, A. Yacoub +8 more
201467 citations
Semantic Scholar
Kte-C19 (anti-CD19 CAR T Cells) Induces Complete Remissions in Patients with Refractory Diffuse Large B-Cell Lymphoma (DLBCL): Results from the Pivotal Phase 2 Zuma-1
S. Neelapu, F. Locke, N. Bartlett, L. Lekakis +33 more
201657 citations
Semantic Scholar
Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia
M. Kashyap, C. Amaya-Chanaga, Deepak Kumar, Brett H. Simmons +15 more
2017Journal of Hematology & Oncology51 citations Open access
Semantic Scholar
Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction.
G. Chessari, I. Hardcastle, J. Ahn, B. Anil +39 more
2021Journal of Medicinal Chemistry45 citations Open access
Semantic Scholar
A Phase 1, Dose-Escalation, Pharmacokinetic and Pharmacodynamic Study of BIIB021 Administered Orally in Patients with Advanced Solid Tumors
M. Saif, C. Takimoto, M. Mita, U. Banerji +5 more
2013Clinical Cancer Research45 citations Open access
Semantic Scholar
Gene Immunotherapy of Chronic Lymphocytic Leukemia: A Phase I Study of Intranodally Injected Adenovirus Expressing a Chimeric CD154 Molecule
J. Castro, Johanna Melo-Cardenas, M. Urquiza, J. Barajas-Gamboa +2 more
2012Cancer Research45 citations Open access
Semantic Scholar
hBfl-1/hNOXA Interaction Studies Provide New Insights on the Role of Bfl-1 in Cancer Cell Resistance and for the Design of Novel Anticancer Agents
E. Barile, G. Marconi, S. De, C. Baggio +6 more
2016ACS Chemical Biology40 citations Open access
Semantic Scholar
Chimeric Antigen Receptor T Cell Therapy in Oncology - Pipeline at a glance: Analysis of the ClinicalTrials.gov database.
E. Moreno-Cortes, J. Forero-Forero, P. A. Lengerke-Diaz, J. Castro
2021Critical reviews in oncology/hematology34 citations
Semantic Scholar
Potent Fluorinated Agelastatin Analogues for Chronic Lymphocytic Leukemia: Design, Synthesis, and Pharmacokinetic Studies
E. Stout, M. Choi, J. Castro, T. Molinski
2014Journal of Medicinal Chemistry34 citations Open access
Semantic Scholar
A Challenging Pie to Splice: Drugging the Spliceosome
B. León, M. Kashyap, W. Chan, Kelsey A. Krug +3 more
2017Angewandte Chemie33 citations Open access
Semantic Scholar
Safety and Preliminary Efficacy Results of a Phase I First-in-Human Study of the Novel Notch-1 Targeting Antibody Brontictuzumab (OMP-52M51) Administered Intravenously to Patients with Hematologic Malignancies
Carla Casulo, J. Ruan, N. Dang, L. Gore +10 more
201629 citations
Semantic Scholar
Genistein Activates Transcription Factor EB and Corrects Niemann–Pick C Phenotype
Graciela Argüello, Elisa Balboa, Pablo J. Tapia, J. Castro +4 more
2021International Journal of Molecular Sciences28 citations Open access
Semantic Scholar
Stabilized Cyclopropane Analogs of the Splicing Inhibitor FD-895
Reymundo Villa, M. Kashyap, Deepak Kumar, T. Kipps +3 more
2013Journal of Medicinal Chemistry27 citations Open access
Semantic Scholar
Sustainable agricultural practices for Mediterranean olive grove. Effect of soil management on soil properties .
O. Nieto, E. Fernández-Ondoño, J. Castro
2014Spanish Journal of Soil Science21 citations Open access
Semantic Scholar
Selectivity in Small Molecule Splicing Modulation.
Deepak Kumar, M. Kashyap, J. L. La Clair, Reymundo Villa +6 more
2016ACS Chemical Biology20 citations
Semantic Scholar
ASTX029, a Novel Dual-mechanism ERK Inhibitor, Modulates Both the Phosphorylation and Catalytic Activity of ERK
J. Munck, V. Berdini, L. Bevan, J. Brothwood +23 more
2021Molecular Cancer Therapeutics19 citations
Semantic Scholar
A Phase I Study of FT819, a First-of-Kind, Off-the-Shelf, iPSC-Derived TCR-Less CD19 CAR T Cell Therapy for the Treatment of Relapsed/Refractory B-Cell Malignancies
Jae H. Park, N. Jain, Andy I. Chen, J. McGuirk +4 more
202015 citations Open access
Semantic Scholar
Updated results from ZUMA-3, a phase 1/2 study of KTE-C19 chimeric antigen receptor (CAR) T cell therapy, in adults with high-burden relapsed/refractory acute lymphoblastic leukemia (R/R ALL).
B. Shah, W. Wierda, G. Schiller, M. Bishop +11 more
201715 citations
Semantic Scholar
Ibrutinib reduces obinutuzumab infusion-related reactions in patients with chronic lymphocytic leukemia and is associated with changes in plasma cytokine levels
Juliana Vélez Luján, P. A. Lengerke-Diaz, C. Jacobs, E. Moreno-Cortes +6 more
2019Haematologica13 citations Open access
Semantic Scholar
Ofatumumab and high-dose methylprednisolone for the treatment of patients with relapsed or refractory chronic lymphocytic leukemia
J. Castro, M. Choi, T. Carvajal, E. Almahasnah +3 more
2014Blood Cancer Journal12 citations Open access
Semantic Scholar
A Carbohydrate-Derived Splice Modulator.
Sachin Dhar, J. L. La Clair, B. León, Justin C. Hammons +4 more
2016Journal of the American Chemical Society11 citations
Semantic Scholar
ZUMA-2: A phase 2 multi-center study evaluating the efficacy of KTE-C19 (Anti-CD19 CAR T cells) in patients with relapsed/refractory Mantle cell lymphoma (R/R MCL)
Michael L. Wang, F. Locke, T. Siddiqi, J. Castro +16 more
20168 citations Open access
Semantic Scholar
BMS-936564 (Anti-CXCR4 Antibody) Induces Specific Leukemia Cell Mobilization and Objective Clinical Responses In CLL Patients Treated Under a Phase I Clinical Trial
C. Amaya-Chanaga, H. Jones, E. Almahasnah, M. Choi +6 more
20138 citations
Semantic Scholar
Study of the Crystallisation Reaction Behaviour to Obtain Struvite
F. Corona, D. Hidalgo, J. M. Martin Marroquin, J. Castro +2 more
2022Waste and Biomass Valorization7 citations Open access
Semantic Scholar
Urban modernization and heritage in the historic centre of Santiago de Chile (1818–1939)
Eugenio Garcés Feliú, José Rosas Vera, Elvira Pérez Villalón, J. Castro
20207 citations
Semantic Scholar
Updated Phase 1 Results of Zuma-3: Kte-C19, an Anti-CD19 Chimeric Antigen Receptor T Cell Therapy, in Adult Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia
W. Wierda, M. Bishop, Olalekan O. Oluwole, A. Logan +16 more
2018Blood7 citations
Semantic Scholar
Chimeric Antigen Receptor T Cell Therapy Pipeline at a Glance: A Retrospective and Systematic Analysis from Clinicaltrials.Gov
E. Cortes, Caleb K Stein, P. Diaz, Cesar A. Ramirez-Segura +1 more
2019Blood5 citations Open access
Semantic Scholar
Adoptive cellular therapy for chronic lymphocytic leukemia and B cell malignancies. CARs and more.
J. Castro, T. Kipps
2016Baillière's Best Practice & Research: Clinical Haematology5 citations
Semantic Scholar
BMS-936564 (MDX1338): A Fully Human Anti-CXCR4 Antibody Induces Apoptosis in an in Vitro Model of Stromal – Leukemia Cell Interaction for Chronic Lymphocytic Leukemia.
M. Kashyap, Deepak Kumar, H. Jones, M. Choi +8 more
20125 citations
Semantic Scholar
Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B
Deepak Kumar, M. Kashyap, Zhe Yu, Ide T. Spaanderman +5 more
2022Aging4 citations Open access
Semantic Scholar
L-carnitine for pegylated-l-asparaginase induced hepatotoxicity.
M. Wieduwilt, A. Goodman, B. Jonas, Ryan D. Cassaday +4 more
20174 citations
Semantic Scholar
A Phase Ib/II Study of Ibrutinib in Combination with Obinutuzumab-Gazyva As First-Line Treatment for Patients with Chronic Lymphocytic Leukemia > 65 Years Old or with Coexisting Conditions
C. Amaya-Chanaga, M. Choi, N. Nguyen, Elizabeth Devore +4 more
2016Blood4 citations
Semantic Scholar
ZUMA-3: A phase 1/2 multi-center study evaluation the safety and efficacy of KTE-C19 anti-CD19 CAR T cells in adult patients with relapsed/refractory B precursor acute lymphoblastic leukemia (R/R ALL)
B. Shah, J. Castro, N. Gökbuget, M. Kersten +11 more
20164 citations Open access
Semantic Scholar
Intratumoral Injection of Ad-ISF35 (Chimeric CD154) Breaks Tolerance and Induces Lymphoma Tumor Regression
M. Urquiza, Johanna Melo-Cardenas, R. Aguillón, T. Kipps +1 more
2015Human Gene Therapy4 citations Open access
Semantic Scholar
Cirmtuzumab (UC-961), a First-in-Class Anti-ROR1 Monoclonal Antibody: Planned Interim Analysis of Initial Phase 1 Cohorts
M. Choi, G. Widhopf, J. Castro, Hongying Li +9 more
20154 citations
Semantic Scholar
Naturaleza y alcance de un laboratorio de neuromarketing
J. Castro, C. Beltrán, Jaime Amaya
2022ECA Sinergia3 citations Open access
Semantic Scholar
gestión de las mercancías desde una perspectiva de los inventarios en prendas de vestir
J. Castro, Christian Salas Fariño
2022Revista Científica Ecociencia3 citations Open access
Semantic Scholar
Use of the Angularis Oris Axial Pattern Buccal Flap for the Correction of Facial Defects in Six Dogs
Marla Tereza Frasson, F. Freitag, R. R. Huppes, J. Pazzini +4 more
2020Acta Scientiae Veterinariae3 citations Open access
Semantic Scholar
The Status of Multiple Myeloma in Colombia: First Report of the Colombian Registry for Hemato-Oncological Diseases (RENEHOC). Asociacion Colombiana De Hematologia y Oncologia (ACHO)
V. Abello, H. Idrobo, C. Sossa, K. Galvez +12 more
2018Blood3 citations
Semantic Scholar
Obinutuzumab (Gazyva) and High-Dose Methylprednisolone (HDMP) Combination for Patients with Chronic Lymphocytic Leukemia (CLL) - a Phase Ib/II Study
J. Castro, C. Amaya-Chanaga, Juliana Vélez Luján, M. Choi +2 more
20173 citations
Semantic Scholar
Durable and Specific Inhibition of ROR1 Signaling Associates with Prolonged Progression Free Survival in Patients with Chronic Lymphocytic Leukemia Treated with Cirmtuzumab
M. Choi, G. Widhopf, Jian-Qiang Yu, Li-Guang Chen +10 more
20173 citations
Semantic Scholar
Immunotherapeutic Targeting of ROR1-Dependent, Non-Canonical Wnt5a-Signaling By Cirmtuzumab: A First-in-Human Phase I Trial for Patients with Intractable Chronic Lymphocytic Leukemia
M. Choi, G. Widhopf, Jian-Qiang Yu, Reilly L. Kidwell +11 more
20163 citations
Semantic Scholar

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T. Kipps×22
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M. Kashyap×10
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