Christina L. Boulton

Most-cited papers

1. Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412.

   E. Weisberg, Christina L. Boulton, Louise M. Kelly, P. Manley +4 more

   2002Cancer Cell641 citations Open access

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2. FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model.

   Louise M. Kelly, Qing Liu, J. Kutok, Ifor R. Williams +2 more

   2002Blood569 citations

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3. CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML).

   Louise M. Kelly, Jin-Chen Yu, Christina L. Boulton, Mutiah Apatira +14 more

   2002Cancer Cell326 citations Open access

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4. PML/RARα and FLT3-ITD induce an APL-like disease in a mouse model

   Louise M. Kelly, J. Kutok, I. Williams, Christina L. Boulton +4 more

   2002Proceedings of the National Academy of Sciences of the United States of America296 citations Open access

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5. Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.

   M. Mohi, I. Williams, Charles R. Dearolf, G. Chan +9 more

   2005Cancer Cell284 citations Open access

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6. Combination of rapamycin and protein tyrosine kinase (PTK) inhibitors for the treatment of leukemias caused by oncogenic PTKs.

   M. Mohi, Christina L. Boulton, T. Gu, D. Sternberg +4 more

   2004Proceedings of the National Academy of Sciences of the United States of America266 citations Open access

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7. PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRα-induced myeloproliferative disease.

   Jan Cools, E. Stover, Christina L. Boulton, J. Gotlib +19 more

   2003Cancer Cell230 citations Open access

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8. PML/RARalpha and FLT3-ITD induce an APL-like disease in a mouse model.

   Louise M. Kelly, J. Kutok, I. Williams, Christina L. Boulton +4 more

   2002Proceedings of the National Academy of Sciences of the United States of America188 citations

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9. Spontaneous X chromosome MI and MII nondisjunction events in Drosophila melanogaster oocytes have different recombinational histories

   K. E. Koehler, Christina L. Boulton, Heather E. Collins, R. French +5 more

   1996Nature Genetics157 citations

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10. Inhibition of mutant FLT 3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC 412

    E. Weisberg, Christina L. Boulton, Louise M. Kelly, P. Manley +4 more

    200293 citations

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11. FLT3 internal tandem duplication mutations induce myeloproliferative or lymphoid disease in a transgenic mouse model

    Benjamin H. Lee, I. Williams, E. Anastasiadou, Christina L. Boulton +8 more

    2005Oncogene88 citations Open access

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12. A Large-Scale Screen for Mutagen-Sensitive Loci in Drosophila

    A. Laurençon, Charisse M. Orme, H. Peters, Christina L. Boulton +8 more

    2004Genetics50 citations Open access

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13. Mechanism of Oncogenesis by Leukemia-Associated Mutants of Shp2 (PTPN11).

    M. Mohi, H. Keilhack, Sarah L. Cohen, Christina L. Boulton +5 more

    20040 citations

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