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M. Ninivaggi · SciRah

Researcher profile · Semantic Scholar

M. Ninivaggi

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M. Ninivaggi — researcher profile on SciRah

h-index: 19
Works: 64
Citations: 999

Most-cited papers

Whole-blood thrombin generation monitored with a calibrated automated thrombogram-based assay.
M. Ninivaggi, R. Apitz-Castro, Y. Dargaud, B. de Laat +2 more
2012Clinical Chemistry130 citations Open access
Semantic Scholar
In vitro assessment, using thrombin generation, of the applicability of prothrombin complex concentrate as an antidote for Rivaroxaban
J. Dinkelaar, P. J. Molenaar, M. Ninivaggi, B. de Laat +2 more
2013Journal of Thrombosis and Haemostasis79 citations Open access
Semantic Scholar
Recommendations for the measurement of thrombin generation: Communication from the ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies
M. Ninivaggi, Romy Laat-Kremers, A. Tripodi, D. Wahl +6 more
2021Journal of Thrombosis and Haemostasis71 citations Open access
Semantic Scholar
Perioperative dilutional coagulopathy treated with fresh frozen plasma and fibrinogen concentrate: a prospective randomized intervention trial
M. Lancé, M. Ninivaggi, S. Schols, M. Feijge +8 more
2012Vox Sanguinis56 citations
Semantic Scholar
Hypoxia Induces a Prothrombotic State Independently of the Physical Activity
M. Ninivaggi, M. de Laat, M. Lancé, Cécile H Kicken +8 more
2015PLoS ONE51 citations Open access
Semantic Scholar
Strenuous exercise induces a hyperreactive rebalanced haemostatic state that is more pronounced in men
D. Huskens, M. Roest, J. Remijn, Joke Konings +12 more
2016Thrombosis and Haemostasis45 citations Open access
Semantic Scholar
Mouse Cytomegalovirus Infection in BALB/c Mice Resembles Virus-Associated Secondary Hemophagocytic Lymphohistiocytosis and Shows a Pathogenesis Distinct from Primary Hemophagocytic Lymphohistiocytosis
Ellen Brisse, Maya Imbrechts, Karen Put, A. Avau +11 more
2016Journal of Immunology44 citations Open access
Semantic Scholar
Towards standardization of thrombin generation assays: Inventory of thrombin generation methods based on results of an International Society of Thrombosis and Haemostasis Scientific Standardization Committee survey
R. D. de Laat-Kremers, M. Ninivaggi, K. Devreese, B. de Laat
2020Journal of Thrombosis and Haemostasis42 citations Open access
Semantic Scholar
VWF, Platelets and the Antiphospholipid Syndrome
Sheng-Shi Huang, M. Ninivaggi, W. Chayoua, B. de Laat
2021International Journal of Molecular Sciences37 citations Open access
Semantic Scholar
Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin generation in liver cirrhosis
R. Kremers, Marie-Claire F. Kleinegris, M. Ninivaggi, B. de Laat +4 more
2017PLoS ONE36 citations Open access
Semantic Scholar
The role of activated coagulation factor XII in overall clot stability and fibrinolysis.
Joke Konings, L. Hoving, Robert A. S. Ariëns, E. Hethershaw +6 more
2015Thrombosis Research36 citations
Semantic Scholar
Clinical Relevance of Isolated Lupus Anticoagulant Positivity in Patients with Thrombotic Antiphospholipid Syndrome
Dong-Mei Yin, P. D. de Groot, M. Ninivaggi, K. Devreese +1 more
2020Thrombosis and Haemostasis33 citations
Semantic Scholar
Additive roles of platelets and fibrinogen in whole-blood fibrin clot formation upon dilution as assessed by thromboelastometry
M. Ninivaggi, M. Feijge, C. Baaten, G. Kuiper +5 more
2013Thrombosis and Haemostasis31 citations
Semantic Scholar
Conformation of beta2glycoprotein I and its effect on coagulation.
M. Ninivaggi, H. Kelchtermans, T. Lindhout, B. de Laat
2012Thrombosis Research31 citations Open access
Semantic Scholar
ST Genesia reference values of 117 healthy donors measured with STG‐BleedScreen, STG‐DrugScreen and STG‐ThromboScreen reagents
M. Ninivaggi, R. D. de Laat-Kremers, A. Carlo, B. de Laat
2020Research and Practice in Thrombosis and Haemostasis27 citations Open access
Semantic Scholar
Thrombin generation assay using factor IXa as a trigger to quantify accurately factor VIII levels in haemophilia A
M. Ninivaggi, Y. Dargaud, R. van Oerle, B. de Laat +2 more
2011Journal of Thrombosis and Haemostasis27 citations Open access
Semantic Scholar
Deciphering the coagulation profile through the dynamics of thrombin activity
R. D. de Laat-Kremers, Qiuting Yan, M. Ninivaggi, M. D. de Maat +1 more
2020Scientific Reports25 citations Open access
Semantic Scholar
Hypobaric Hypoxia Causes Elevated Thrombin Generation Mediated by FVIII that is Balanced by Decreased Platelet Activation
Cécile H Kicken, M. Ninivaggi, Joke Konings, M. Moorlag +5 more
2018Thrombosis and Haemostasis25 citations
Semantic Scholar
Population-wide persistent hemostatic changes after vaccination with ChAdOx1-S
B. de Laat, H. Stragier, R. D. de Laat-Kremers, M. Ninivaggi +14 more
2022Frontiers in Cardiovascular Medicine20 citations Open access
Semantic Scholar
Increased BMI and Blood Lipids Are Associated With a Hypercoagulable State in the Moli-sani Cohort
R. D. de Laat-Kremers, A. Di Castelnuovo, L. N. van der Vorm, S. Costanzo +11 more
2022Frontiers in Cardiovascular Medicine13 citations Open access
Semantic Scholar
Deciphered coagulation profile to diagnose the antiphospholipid syndrome using artificial intelligence.
R. D. de Laat-Kremers, D. Wahl, S. Zuily, M. Ninivaggi +6 more
2021Thrombosis Research12 citations Open access
Semantic Scholar
Vascular activation is a strong predictor of mortality in coronavirus disease 2019 patients on the ICU.
R. De Jongh, M. Ninivaggi, D. Mesotten, Cui Bai +8 more
2021Blood Coagulation and Fibrinolysis12 citations
Semantic Scholar
A thrombin-driven neural net diagnoses the antiphospholipid syndrome without the need for interruption of anticoagulation
R. D. de Laat-Kremers, Denis Wahl, S. Zuily, M. Ninivaggi +5 more
2024Blood Advances10 citations Open access
Semantic Scholar
Tailoring the effect of antithrombin-targeting therapy in haemophilia A using in silico thrombin generation
R. D. de Laat-Kremers, M. Ninivaggi, I. van Moort, M. D. de Maat +1 more
2021Scientific Reports10 citations Open access
Semantic Scholar
Whole blood thrombin generation in Bmal1-deficient mice
M. Ninivaggi, H. Kelchtermans, M. Kuijpers, Bianca Hemmeryckx +4 more
2014Thrombosis and Haemostasis10 citations Open access
Semantic Scholar
Theme 2: Epidemiology, Biomarkers, and Imaging of Venous Thromboembolism (and postthrombotic syndrome).
H. Spronk, S. Cannegieter, P. Morange, T. Hackeng +9 more
2015Thrombosis Research9 citations
Semantic Scholar
Reference values for thrombin dynamics in platelet rich plasma
Qiuting Yan, M. Ninivaggi, B. de Laat, R. D. de Laat-Kremers
2020Platelets8 citations
Semantic Scholar
Coagulation parameters predict COVID-19-related thrombosis in a neural network with a positive predictive value of 98%
R. D. de Laat-Kremers, R. De Jongh, M. Ninivaggi, A. Fiolet +3 more
2022Frontiers in Immunology7 citations Open access
Semantic Scholar
Evaluating the thrombin generation profiles of four different rFVIII products in FVIII‐deficient plasma using FIXa and FXIa activation
D. Brophy, E. Martin, M. Ninivaggi, B. Mohammed +5 more
2018Haemophilia7 citations
Semantic Scholar
Haemostatic differences between SARS-CoV-2 PCR-positive and negative patients at the time of hospital admission
B. de Laat, M. Traets, R. D. de Laat-Kremers, S. Verweij +12 more
2022PLoS ONE6 citations Open access
Semantic Scholar
Semi-automated thrombin dynamics applying the ST Genesia thrombin generation assay
A. Carlo, Qiuting Yan, H. ten Cate, R. D. de Laat-Kremers +2 more
2022Frontiers in Cardiovascular Medicine5 citations Open access
Semantic Scholar
An Elementary Textbook of Ayurveda: Medicine With a Six Thousand Year Old Tradition
M. Ninivaggi, F. John
20015 citations
Semantic Scholar
Age- and sex-dependency of thrombin generation parameters in the general Italian population: the Moli-sani study
S. Costanzo, B. de Laat, A. Di Castelnuovo, L. N. van der Vorm +6 more
2025Frontiers in Cardiovascular Medicine4 citations Open access
Semantic Scholar
Thrombomodulin is a stronger indicator of combined oral contraceptives-induced activated protein C pathway resistance in the thrombin generation test than activated protein C
M. Ninivaggi, L. Sokolova, Demy Donkervoort, B. de Laat +1 more
2024Frontiers in Cardiovascular Medicine4 citations Open access
Semantic Scholar
Abacavir use is associated with increased prothrombin conversion
Qiuting Yan, Sheng-Shi Huang, W. van der Heijden, M. Ninivaggi +5 more
2023Frontiers in Immunology4 citations Open access
Semantic Scholar
Low antithrombin levels are associated with low risk of cardiovascular death but are a risk factor for cancer mortality
L. Iacoviello, R. D. de Laat-Kremers, S. Costanzo, Qiuting Yan +7 more
2022PLoS ONE4 citations Open access
Semantic Scholar
Early transfusion with FFP or FFP plus fibrinogen concentrate in massive hemorrhage: A randomized intervention trial: 6AP5-5
M. Lancé, M. Ninivaggi, K. Hamulýak, E. V. van Pampus +2 more
20114 citations
Semantic Scholar
Nosocomial infections in hiv infected patients in a large teaching hospital
J. Selva, M. Ninivaggi, A. Toledo, S. Forlenza
19934 citations
Semantic Scholar
Endogenous Thrombin Potential and Time-Dependent Thrombin Generation Parameters are Independent Risk Factors for Mortality in the General Population.
R. D. de Laat-Kremers, S. Costanzo, M. Roest, A. De Curtis +7 more
2024Journal of Thrombosis and Haemostasis3 citations
Semantic Scholar
Periprocedural continuation versus interruption of oral anticoagulant drugs during transcatheter aortic valve implantation: rationale and design of the POPular PAUSE TAVI trial.
D. van Ginkel, W. L. Bor, C. Dubois, Hugo M. Aarts +36 more
2023EuroIntervention3 citations Open access
Semantic Scholar
Assessing the individual roles of FII, FV, and FX activity in the thrombin generation process
Cuicui Bai, Joke Konings, M. Ninivaggi, M. Lancé +2 more
2022Frontiers in Cardiovascular Medicine3 citations Open access
Semantic Scholar
Functional changes in hemostasis during asexual and sexual parasitemia in a controlled human malaria infection
Sheng-Shi Huang, W. van der Heijden, Isaie J. Reuling, Jun Wan +11 more
2022PLoS ONE2 citations Open access
Semantic Scholar
Increased Thrombin Generation and Fibrin Formation In Premature Aging BMAL1 Deficient Mice
M. Ninivaggi, H. Kelchtermans, M. Kuipers, Bianca Hemmeryckx +4 more
20132 citations
Semantic Scholar
Variability in Exposure of Epitope G40-R43 of Domain I in Commercial Anti-β 2 -Glycoprotein I IgG Elisas Influences the Diagnosis of the Antiphospholipid Syndrome
L. Pelkmans, H. Kelchtermans, M. Ninivaggi, T. Lindhout +3 more
20122 citations
Semantic Scholar
A Short Thrombin Generation Time-to-Peak/Lag Time Ratio Is an Independent Risk Factor for Mortality in the General Population
R. D. de Laat-Kremers, S. Costanzo, M. Roest, A. De Curtis +7 more
2023Blood1 citations Open access
Semantic Scholar
Domain Specificity of Anti-Prothrombin Antibodies That Express Lupus Anticoagulant Activity
R. Gehlen, T. Noordermeer, A. Vandevelde, W. Chayoua +7 more
2023Blood1 citations Open access
Semantic Scholar
PB1767 Oral contraceptive use is associated with increased prothrombin conversion and a more procoagulant thrombin generation profile only in women below 45 years of age: a Moli-sani cohort study
R. D. de Laat-Kremers, A. De Curtis, S. Costanzo, A. Di Castelnuovo +6 more
2026Research and Practice in Thrombosis and Haemostasis0 citations Open access
Semantic Scholar
Interpreting high levels of unfolded Von Willebrand Factor in patients with the antiphospholipid syndrome
R. D. de Laat-Kremers, Shengshi Huang, H. ten Cate, M. Ninivaggi +2 more
2024Frontiers in Immunology0 citations Open access
Semantic Scholar
Measuring Thrombin Generation in Platelet Rich Plasma with the ST Genesia
M. Ninivaggi, R. D. de Laat-Kremers, B. de Laat
2023Blood0 citations Open access
Semantic Scholar
Neural Network Diagnoses the Antiphospholipid Syndrome without Interrupting Anticoagulant Therapy
R. D. de Laat-Kremers, D. Wahl, S. Zuily, M. Ninivaggi +5 more
2022Blood0 citations Open access
Semantic Scholar

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