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H. Mellstedt · SciRah

Researcher profile · Semantic Scholar

H. Mellstedt

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H. Mellstedt — researcher profile on SciRah

h-index: 55
Works: 293
Citations: 10K

Most-cited papers

A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease.
D. Bagnara, M. Kaufman, C. Calissano, Sonia Marsilio +14 more
2011Blood221 citations Open access
Semantic Scholar
Ror1, a cell surface receptor tyrosine kinase is expressed in chronic lymphocytic leukemia and may serve as a putative target for therapy
Amir Hossein Daneshmanesh, Eva Mikaelsson, M. Jeddi-Tehrani, A. Bayat +9 more
2008International Journal of Cancer194 citations Open access
Semantic Scholar
T cells in chronic lymphocytic leukemia display dysregulated expression of immune checkpoints and activation markers
M. Palma, G. Gentilcore, K. Heimersson, F. Mozaffari +6 more
2016Haematologica153 citations Open access
Semantic Scholar
The receptor tyrosine kinase ROR1--an oncofetal antigen for targeted cancer therapy.
M. Hojjat-Farsangi, A. Moshfegh, A. Daneshmanesh, Abdul Salam Khan +3 more
2014Seminars in Cancer Biology94 citations
Semantic Scholar
T cells in monoclonal gammopathies.
H. Mellstedt, G. Holm, D. Pettersson, M. Björkholm +4 more
2009Scandinavian Journal of Haematology89 citations
Semantic Scholar
Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies
A. Daneshmanesh, A. Porwit, M. Hojjat-Farsangi, M. Jeddi-Tehrani +8 more
2013Leukemia and Lymphoma88 citations Open access
Semantic Scholar
Silencing of ROR1 and FMOD with siRNA results in apoptosis of CLL cells
A. Choudhury, Katja Derkow, Amir Hossein Daneshmanesh, Eva Mikaelsson +4 more
2010British Journal of Haematology88 citations Open access
Semantic Scholar
Long-term Idiotype Vaccination Combined with Interleukin-12 (IL-12), or IL-12 and Granulocyte Macrophage Colony-Stimulating Factor, in Early-Stage Multiple Myeloma Patients
L. Hansson, A. Abdalla, A. Moshfegh, A. Choudhury +4 more
2007Clinical Cancer Research67 citations Open access
Semantic Scholar
Inhibition of the Receptor Tyrosine Kinase ROR1 by Anti-ROR1 Monoclonal Antibodies and siRNA Induced Apoptosis of Melanoma Cells
M. Hojjat-Farsangi, F. Ghaemimanesh, A. Daneshmanesh, A. Bayat +4 more
2013PLoS ONE64 citations Open access
Semantic Scholar
The Tyrosine Kinase Receptor ROR1 Is Constitutively Phosphorylated in Chronic Lymphocytic Leukemia (CLL) Cells
M. Hojjat-Farsangi, Abdul Salam Khan, A. Daneshmanesh, A. Moshfegh +6 more
2013PLoS ONE62 citations Open access
Semantic Scholar
Telomerase (hTERT 611-626) serves as a tumor antigen in B-cell chronic lymphocytic leukemia and generates spontaneously antileukemic, cytotoxic T cells.
P. Kokhaei, M. Palma, L. Hansson, A. Osterborg +2 more
2007Experimental Hematology61 citations Open access
Semantic Scholar
Vaccines for the treatment of non-small cell lung cancer: investigational approaches and clinical experience.
H. Mellstedt, J. Vansteenkiste, N. Thatcher
2011Lung Cancer60 citations
Semantic Scholar
Vaccination with dendritic cells loaded with tumor apoptotic bodies (Apo-DC) in patients with chronic lymphocytic leukemia: effects of various adjuvants and definition of immune response criteria
M. Palma, L. Hansson, A. Choudhury, B. Näsman-Glaser +9 more
2012Cancer Immunology and Immunotherapy59 citations
Semantic Scholar
Overexpression of Orphan Receptor Tyrosine Kinase Ror1 as a Putative Tumor-Associated Antigen in Iranian Patients with Acute Lymphoblastic Leukemia
M. Shabani, H. Asgarian-Omran, M. Jeddi-Tehrani, P. Vossough +10 more
2008Tumor Biology52 citations
Semantic Scholar
Expression profile of orphan receptor tyrosine kinase (ROR1) and Wilms' tumor gene 1 (WT1) in different subsets of B-cell acute lymphoblastic leukemia
M. Shabani, H. Asgarian-Omran, P. Vossough, R. Sharifian +8 more
2008Leukemia and Lymphoma51 citations
Semantic Scholar
Expression of Erythropoietin Receptor and In vitro Functional Effects of Epoetins in B-Cell Malignancies
P. Kokhaei, A. Abdalla, L. Hansson, Eva Mikaelsson +5 more
2007Clinical Cancer Research50 citations Open access
Semantic Scholar
First-in-class oral small molecule inhibitor of the tyrosine kinase ROR1 (KAN0439834) induced significant apoptosis of chronic lymphocytic leukemia cells
M. Hojjat-Farsangi, A. H. Daneshmanesh, A. Khan, J. Shetye +16 more
2018Leukemia48 citations Open access
Semantic Scholar
A receptor tyrosine kinase ROR1 inhibitor (KAN0439834) induced significant apoptosis of pancreatic cells which was enhanced by erlotinib and ibrutinib
A. Daneshmanesh, M. Hojjat-Farsangi, Amineh Ghaderi, A. Moshfegh +8 more
2018PLoS ONE42 citations Open access
Semantic Scholar
The PI3K/AKT/mTOR pathway is involved in direct apoptosis of CLL cells induced by ROR1 monoclonal antibodies
Amir Hossein Daneshmanesh, M. Hojjat-Farsangi, A. Moshfegh, Abdul Salam Khan +3 more
2015British Journal of Haematology40 citations Open access
Semantic Scholar
ROR1 is Expressed in Diffuse Large B-Cell Lymphoma (DLBCL) and a Small Molecule Inhibitor of ROR1 (KAN0441571C) Induced Apoptosis of Lymphoma Cells
Amineh Ghaderi, A. Daneshmanesh, A. Moshfegh, P. Kokhaei +10 more
2020Biomedicines37 citations Open access
Semantic Scholar
Immunoglobulin heavy chain variable region gene usage and mutational status of the leukemic B cells in Iranian patients with chronic lymphocytic leukemia
M. Hojjat-Farsangi, M. Jeddi-Tehrani, S. Razavi, R. Sharifian +3 more
2009Cancer Science36 citations Open access
Semantic Scholar
Performance of calibration standards for antigen quantitation with flow cytometry in chronic lymphocytic leukemia
E. Rossmann, R. Lenkei, J. Lundin, H. Mellstedt +1 more
2007Cytometry. Part B, Clinical cytometry36 citations
Semantic Scholar
Monoclonal blood lymphocytes in benign monoclonal gammopathy and multiple myeloma in relation to clinical stage.
D. Pettersson, H. Mellstedt, G. Holm, M. Björkholm
2009Scandinavian Journal of Haematology34 citations
Semantic Scholar
Polymorphisms within methotrexate pathway genes: Relationship between plasma methotrexate levels, toxicity experienced and outcome in pediatric acute lymphoblastic leukemia
M. Esmaili, A. Kazemi, Mohammad Faranoush, H. Mellstedt +4 more
2020Iranian Journal of Basic Medical Sciences31 citations
Semantic Scholar
Dendritic cell regulation of NK‐cell responses involves lymphotoxin‐α, IL‐12, and TGF‐β
D. Sarhan, M. Palma, Yumeng Mao, L. Adamson +4 more
2015European Journal of Immunology31 citations Open access
Semantic Scholar
Dishevelled proteins are significantly upregulated in chronic lymphocytic leukaemia
Abdul Salam Khan, M. Hojjat-Farsangi, A. Daneshmanesh, L. Hansson +4 more
2016Tumor Biology30 citations
Semantic Scholar
T cells from indolent CLL patients prevent apoptosis of leukemic B cells in vitro and have altered gene expression profile
S. Kiaii, P. Kokhaei, F. Mozaffari, E. Rossmann +9 more
2012Cancer Immunology and Immunotherapy25 citations Open access
Semantic Scholar
Clonality and methylation status of the epstein‐barr virus (EBV) genomes in IN V7W‐infected EBV‐carrying chronic lymphocytic leukemia (CLL) cell lines
N. Lewin, J. Minárovits, Gunther Weber, B. Ehlin-Henriksson +4 more
2007International Journal of Cancer25 citations
Semantic Scholar
Ibrutinib-A double-edge sword in cancer and autoimmune disorders
P. Kokhaei, Farhad Jadidi-Niaragh, Abdolreza Sotoodeh Jahromi, A. Osterborg +2 more
2016Journal of drug targeting (Print)24 citations
Semantic Scholar
Development of a dendritic cell-based vaccine for chronic lymphocytic leukemia
M. Palma, L. Adamson, L. Hansson, P. Kokhaei +4 more
2008Cancer Immunology and Immunotherapy24 citations
Semantic Scholar
A ROR1 Small Molecule Inhibitor (KAN0441571C) Induced Significant Apoptosis of Mantle Cell Lymphoma (MCL) Cells
Amineh Ghaderi, Wen Zhong, Mohammad Ali Okhovat, J. Aschan +7 more
2022Pharmaceutics21 citations Open access
Semantic Scholar
Predicting ROR1/BCL2 combination targeted therapy of small cell carcinoma of the lung
Walter Z. Wang, K. Shilo, J. Amann, Alyssa Shulman +5 more
2021Cell Death and Disease20 citations Open access
Semantic Scholar
Telomere length and expression of human telomerase reverse transcriptase splice variants in chronic lymphocytic leukemia.
M. Palma, A. Parker, M. Hojjat-Farsangi, J. Forster +4 more
2013Experimental Hematology19 citations
Semantic Scholar
Idiotype protein vaccination in combination with adjuvant cytokines in patients with multiple myeloma--evaluation of T-cell responses by different read-out systems.
A. Abdalla, L. Hansson, I. Eriksson, B. Näsman-Glaser +4 more
2007Haematologica19 citations Open access
Semantic Scholar
Extreme hyponatremia in patients with myelomatosis: an effect of cationic paraproteins.
B. Bloth, T. Christensson, H. Mellstedt
2009Acta Medica Scandinavica18 citations
Semantic Scholar
A prospective study of HL-A antigen phenotypes and lymphocyte abnormalities in Hodgkin's disease.
M. Björkholm, G. Holm, B. Johansson, H. Mellstedt +1 more
2008Tissue Antigens17 citations
Semantic Scholar
Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia
M. Hojjat-Farsangi, M. Jeddi-Tehrani, A. Daneshmanesh, F. Mozaffari +8 more
2015PLoS ONE15 citations Open access
Semantic Scholar
A Small Molecule Targeting the Intracellular Tyrosine Kinase Domain of ROR1 (KAN0441571C) Induced Significant Apoptosis of Non-Small Cell Lung Cancer (NSCLC) Cells
Amineh Ghaderi, Mohammad Ali Okhovat, Jemina Lehto, L. De Petris +11 more
2023Pharmaceutics14 citations Open access
Semantic Scholar
A Proline/Arginine-Rich End Leucine-Rich Repeat Protein (PRELP) Variant Is Uniquely Expressed in Chronic Lymphocytic Leukemia Cells
Eva Mikaelsson, A. Österborg, M. Jeddi-Tehrani, P. Kokhaei +7 more
2013PLoS ONE14 citations Open access
Semantic Scholar
Lenalidomide as immune adjuvant to a dendritic cell vaccine in chronic lymphocytic leukemia patients
M. Palma, L. Hansson, T. Mulder, L. Adamson +9 more
2018European Journal of Haematology13 citations
Semantic Scholar
Patients with activated B-cell like diffuse large B-cell lymphoma in high and low infectious disease areas have different inflammatory gene signatures
T. Högfeldt, A. Bahnassy, A. Kwiecińska, A. Österborg +7 more
2013Leukemia and Lymphoma11 citations
Semantic Scholar
Phase I–II study of lenalidomide and alemtuzumab in refractory chronic lymphocytic leukemia (CLL): effects on T cells and immune checkpoints
M. Winqvist, F. Mozaffari, M. Palma, Sandra Eketorp Sylvan +4 more
2016Cancer Immunology and Immunotherapy9 citations Open access
Semantic Scholar
Iron intoxication in two adult patients.
F. Eriksson, S. Johansson, H. Mellstedt, O. Strandberg +1 more
2009Acta Medica Scandinavica9 citations
Semantic Scholar
Targeting the Receptor Tyrosine Kinase ROR1 by Small Molecules.
M. Hojjat-Farsangi, A. Moshfegh, J. Schultz, M. Norin +3 more
2021Handbook of Experimental Pharmacology8 citations
Semantic Scholar
Opticin, a small leucine-rich proteoglycan, is uniquely expressed and translocated to the nucleus of chronic lymphocytic leukemia cells
Eva Mikaelsson, A. Österborg, Zahra Tahmasebi Fard, A. Mahmoudi +7 more
2013Experimental Hematology & Oncology8 citations Open access
Semantic Scholar
Effect of ROR1-targeting small molecules on chronic lymphocytic leukemia (CLL) cells.
H. Mellstedt, Salam Khan, J. Vågberg, S. Byström +6 more
20128 citations
Semantic Scholar
Correlation of immunophenotype to morphology in unfavourable non-Hodgkin lymphoma.
B. Christensson, C. Lindemalm, B. Johansson, H. Mellstedt +2 more
2009Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology8 citations
Semantic Scholar
Differential expression of viral agents in lymphoma tissues of patients with ABC diffuse large B-cell lymphoma from high and low endemic infectious disease regions.
T. Högfeldt, C. Jaing, Kevin Mc Loughlin, J. Thissen +10 more
2016Oncology Letters7 citations Open access
Semantic Scholar
Expression of microRNA-1234 related signal transducer and activator of transcription 3 in patients with diffuse large B-cell lymphoma of activated B-cell like type from high and low infectious disease areas
T. Högfeldt, P. Johnsson, D. Grandér, A. Bahnassy +8 more
2014Leukemia and Lymphoma7 citations
Semantic Scholar
Long‐term effects of idiotype vaccination on the specific T‐cell response in peripheral blood and bone marrow of multiple myeloma patients
A. Abdalla, L. Hansson, I. Eriksson, B. Näsman-Glaser +2 more
2007European Journal of Haematology7 citations
Semantic Scholar

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A. Österborg×29
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A. Österborg — researcher profile on SciRah
M. Hojjat-Farsangi×18
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M. Hojjat-Farsangi — researcher profile on SciRah
L. Hansson×16
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L. Hansson — researcher profile on SciRah
A. Moshfegh×16
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A. Moshfegh — researcher profile on SciRah

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P. Kokhaei — researcher profile on SciRah

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M. Palma — researcher profile on SciRah

M. Jeddi-Tehrani×9

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H. Rabbani — researcher profile on SciRah

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J. Schultz — researcher profile on SciRah

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Eva Mikaelsson — researcher profile on SciRah