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R. J. Bonney · SciRah

Researcher profile · Semantic Scholar

R. J. Bonney

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R. J. Bonney — researcher profile on SciRah

h-index: 31
Works: 83
Citations: 3,356

Most-cited papers

Macrophages synthesise and release prostaglandins in response to inflammatory stimuli
J. Humes, R. J. Bonney, L. Pelus, M. Dahlgren +3 more
1977Nature553 citations
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Regulation of prostaglandin synthesis and of the selective release of lysosomal hydrolases by mouse peritoneal macrophages.
R. J. Bonney, Paul D. Wightman, Philip Davies, S. Sadowski +2 more
1978Biochemical Journal228 citations Open access
Semantic Scholar
Evidence for two sources of arachidonic acid for oxidative metabolism by mouse peritoneal macrophages.
J. Humes, S. Sadowski, M. Galavage, M. Goldenberg +3 more
1982Journal of Biological Chemistry224 citations Open access
Semantic Scholar
The diminished production of arachidonic acid oxygenation products by elicited mouse peritoneal macrophages: possible mechanisms.
J. Humes, S. Burger, M. Galavage, F. A. Kuehl +4 more
1980Journal of Immunology158 citations Open access
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Cephalosporin antibiotics can be modified to inhibit human leukocyte elastase
J. Doherty, B. Ashe, L. Argenbright, P. L. Barker +15 more
1986Nature144 citations
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Prostaglandin and leukotriene synthesis in mouse ears inflamed by arachidonic acid.
Evan E. Opas, R. J. Bonney, J. Humes
1985Journal of Investigative Dermatology124 citations Open access
Semantic Scholar
Physiological and Pharmacological Regulation of Prostaglandin and Leukotriene Production by Macrophages
R. J. Bonney, J. Humes
1984Journal of Leukocyte Biology116 citations
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Antigen-antibody complexes stimulate the synthesis and release of prostaglandins by mouse peritoneal macrophages.
R. J. Bonney, Peter Naruns, P. Davies, J. Humes
1979Prostaglandins112 citations
Semantic Scholar
[Identification and characterization of two phospholipase A2 activities in resident mouse peritoneal macrophages].
P. Wightman, J. Humes, P. Davies, R. J. Bonney
1981Biochemical Journal100 citations Open access
Semantic Scholar
Lysosomotropic agents. 1. Synthesis and cytotoxic action of lysosomotropic detergents.
R. Firestone, J. Pisano, R. J. Bonney
1979Journal of Medicinal Chemistry96 citations
Semantic Scholar
Secretory products of mononuclear phagocytes: a brief review.
P. Davies, R. J. Bonney
1979Journal of the Reticuloendothelial Society92 citations
Semantic Scholar
Food and light as separate entrainment signals for rat liver enzymes.
H. Hopkins, R. J. Bonney, P. Walker, James D. Yager +1 more
1973Advances in Enzyme Regulation78 citations
Semantic Scholar
Primary monolayer cultures of adult rat liver parenchymal cells suitable for study of the regulation of enzyme synthesis
R. J. Bonney, Joyce E. Becker, P. Walker, R. Potter
1974In Vitro70 citations
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Effect of RNA and protein synthesis inhibitors on the release of inflammatory mediators by macrophages responding to phorbol myristate acetate.
R. J. Bonney, P. Wightman, M. Dahlgren, Philip Davies +2 more
1980Biochimica et Biophysica Acta62 citations
Semantic Scholar
Isoenzyme patterns in parenchymal and non-parenchymal cells isolated from regenerating and regenerated rat liver.
R. J. Bonney, P. Walker, V. Potter
1973Biochemical Journal59 citations Open access
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Regulation of macrophage eicosanoid production by hydroperoxy-and hydroxy-eicosatetraenoic acids.
J. Humes, E. Opas, M. Galavage, D. Soderman +1 more
1986Biochemical Journal56 citations Open access
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Pharmacological effects of non-steroidal antiinflammatory agents on prostaglandin and leukotriene synthesis in mouse peritoneal macrophages.
J. Humes, S. Sadowski, Mary Galavage, M. Goldenberg +3 more
1983Biochemical Pharmacology55 citations
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The selective release of phospholipase A2 by resident mouse peritoneal macrophages.
Paul D. Wightman, M. Dahlgren, Philip Davies, R. J. Bonney
1981Biochemical Journal54 citations Open access
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Extended expression of differentiated function in primary cultures of adult liver parenchymal cells maintained on nitrocellulose filters. I. Induction of phosphoenolpyruvate carboxykinase and tyrosine aminotransferase.
C. Savage, R. J. Bonney
1978Experimental Cell Research53 citations
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Glycolytic isoenzymes and glycogen metabolism in regenerating liver from rats on controlled feeding schedules.
R. J. Bonney, H. Hopkins, P. Walker, V. Potter
1973Biochemical Journal49 citations Open access
Semantic Scholar
Mononuclear phagocytes from carrageenan-induce granulomas. Isolation, cultivation, and characterization
R. J. Bonney, I. Gery, Tsau-Yen Lin, M. Meyenhofer +2 more
1978Journal of Experimental Medicine46 citations Open access
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Identification and characterization of a phospholipase C activity in resident mouse peritoneal macrophages. Inhibition of the enzyme by phenothiazines.
Paul D. Wightman, M. Dahlgren, James C. Hall, Philip Davies +1 more
1981Biochemical Journal45 citations Open access
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Possible autoregulatory functions of the secretory products of mononuclear phagocytes.
R. J. Bonney, Philip Davies
1984Contemporary topics in immunobiology44 citations
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Lipoxygenase pathways of macrophages.
R. J. Bonney, E. Opas, J. Humes
1985Federation proceedings43 citations
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Role of leukocyte factors and cationic polyelectrolytes in phagocytosis of group A streptococci and Candida albicans by neutrophils, macrophages, fibroblasts and epithelial cells: modulation by anionic polyelectrolytes in relation to pathogenesis of chronic inflammation.
Isaac Ginsburg, Michael N. Sela, Abraham Morag, Z. Ravid +8 more
1981Inflammation42 citations
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Inhibition of human leukocyte elastase. 4. Selection of a substituted cephalosporin (L-658,758) as a topical aerosol.
P. Finke, Shrenik K. Shah, B. Ashe, Richard G. Ball +6 more
1992Journal of Medicinal Chemistry40 citations Open access
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Phospholipase activity in skin after application of phorbol esters and 3-methylcholanthrene.
E. Bresnick, Glenn Bailey, R. J. Bonney, Paul D. Wightman
1981Carcinogenesis38 citations
Semantic Scholar
Protein kinase activation of phospholipase A2 in sonicates of mouse peritoneal macrophages.
Paul D. Wightman, M. Dahlgren, R. J. Bonney
1982Journal of Biological Chemistry36 citations Open access
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A comparison of alpha 1-proteinase inhibitor methoxysuccinyl-Ala-Ala-Pro-Val-chloromethylketone and specific beta-lactam inhibitors in an acute model of human polymorphonuclear leukocyte elastase-induced lung hemorrhage in the hamster.
D. Fletcher, D. Osinga, K. M. Hand, P. S. Dellea +7 more
1990American Review of Respiratory Disease35 citations
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Inhibitor of phospholipase A2 blocks eicosanoid and platelet activating factor biosynthesis and has topical anti-inflammatory activity.
K. Tramposch, F. Chilton, P. Stanley, R. Franson +5 more
1994Journal of Pharmacology and Experimental Therapeutics34 citations
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Pharmacological profile of the substituted beta‐lactam L‐659,286: A member of a new class of human PMN elastase inhibitors
R. J. Bonney, B. Ashe, A. Maycock, P. S. Dellea +13 more
1989Journal of Cellular Biochemistry28 citations
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The role of macrophage secretory products in chronic inflammatory processes.
Philip Davies, R. J. Bonney, John L. Humes, F. A. Kuehl
1980Journal of Investigative Dermatology25 citations Open access
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Prostaglandin E2 and prostacyclin elevate cyclic AMP levels in elicited populations of mouse peritoneal macrophages.
R. J. Bonney, S. Burger, P. Davies, F. Kuehl +1 more
1980Advances in prostaglandin and thromboxane research25 citations
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Effect of methotrexate on thymidylate synthetase in cultured parenchymal cells isolated from regenerating rat liver.
R. J. Bonney, F. Maley
1975Cancer Research24 citations
Semantic Scholar
Phorbol myristate acetate induces the secretion of an elastase by populations of resident and elicited mouse peritoneal macrophages.
M. Dahlgren, Philip Davies, R. J. Bonney
1980Biochimica et Biophysica Acta22 citations
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Diurnal rhythms of hepatic carbohydrate metabolism during development of the rat.
P. Walker, R. J. Bonney, V. Potter
1974Biochemical Journal22 citations Open access
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Inhibition of the release of prostaglandins, leukotrienes and lysosomal acid hydrolases from macrophages by selective inhibitors of lecithin biosynthesis.
R. J. Bonney, Paul D. Wightman, M. Dahlgren, S. Sadowski +4 more
1983Biochemical Pharmacology21 citations
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The Discovery and Biologic Properties of Cephalosporin‐Based Inhibitors of PMN Elastase
P. Davies, B. Ashe, R. J. Bonney, C. Dorn +12 more
1991Annals of the New York Academy of Sciences20 citations
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Adult liver parenchymal cells in primary culture: Characteristics and cell recognition standards
R. J. Bonney
1974In Vitro19 citations
Semantic Scholar
Prevention of human leukocyte elastase-mediated lung damage by 3-alkyl-4-azetidinones
W. Hagmann, Shrenik K. Shah, P. DornConrad, Laura A. O'Grady +15 more
199118 citations
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The Synthesis of Arachidonic Acid Oxygenation Products by Various Mononuclear Phagocyte Populations
P. Davies, R. J. Bonney, J. Humes, F. A. Kuehl +2 more
198018 citations
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Lysosomotropic agents. 4. Carbobenzoxyglycylphenylalanyl, a new protease-sensitive masking group for introduction into cells.
R. Firestone, J. Pisano, P. J. Bailey, Anita Sturm +6 more
1982Journal of Medicinal Chemistry17 citations
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SECRETION OF ARACHIDONIC ACID OXYGENATION PRODUCTS BY MONONUCLEAR PHAGOCYTES: THEIR POSSIBLE SIGNIFICANCE AS MODULATORS OF LYMPHOCYTS FUNCTION
P. Davies, R. J. Bonney, J. Humes, F. Kuehl
198015 citations
Semantic Scholar
The effect of anti-rheumatic agents on macrophage function.
P. Davies, R. J. Bonney, J. Humes, F. A. Kuehl
1982International Journal of Immunopharmacology14 citations
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Recent studies on the secretory activity of mononuclear phagocytes with special reference to prostaglandins
P. Davies, R. J. Bonney, M. Dahlgren, L. Pelus +2 more
197712 citations
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Biochemical and biological activities of 2,3-dihydro-6-[3-(2-hydroxymethyl)phenyl-2-propenyl]-5-benzofuranol (L-651,896), a novel topical anti-inflammatory agent.
R. J. Bonney, P. Davies, H. Dougherty, Robert W. Egan +11 more
1987Biochemical Pharmacology11 citations
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Direct Assay of Aα(1–21), a PMN Elastase‐Specific Cleavage Product of Fibrinogen, in the Chimpanzee
R. Mumford, H. Williams, J. Mao, M. Dahlgren +11 more
1991Annals of the New York Academy of Sciences10 citations
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The Pharmacology of a Novel Topical Retinoid, BMY 30123: Comparison with Tretinoin
K. Tramposch, Xina Nair, Gerard J. Gendimenico, G. Tetrault +4 more
1992The Journal of pharmacy and pharmacology9 citations
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Arachidonic acid oxygenation products produced by mouse peritoneal macrophages responding to inflammatory stimuli.
R. J. Bonney, P. Davies, F. Kuehl, J. Humes
1980Journal of the Reticuloendothelial Society9 citations
Semantic Scholar
Potency of antileukoprotease and alpha 1-antitrypsin to inhibit degradation of fibrinogen by adherent polymorphonuclear leukocytes from normal subjects and patients with chronic granulomatous disease.
Jan Stolk, Philip Davies, J. Kramps, J. H. Dijkman +6 more
1992American Journal of Respiratory Cell and Molecular Biology8 citations
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J. Humes×23
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J. Humes — researcher profile on SciRah
P. Davies×18
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M. Dahlgren×12
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Philip Davies×10
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Philip Davies — researcher profile on SciRah

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F. A. Kuehl — researcher profile on SciRah

Paul D. Wightman×7

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Paul D. Wightman — researcher profile on SciRah

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P. Finke — researcher profile on SciRah

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D. Fletcher — researcher profile on SciRah

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R. Mumford — researcher profile on SciRah

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S. Sadowski — researcher profile on SciRah

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J. Doherty — researcher profile on SciRah

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B. Ashe — researcher profile on SciRah