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H. Ruven · SciRah

Researcher profile · Semantic Scholar

H. Ruven

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H. Ruven — researcher profile on SciRah

h-index: 35
Works: 79
Citations: 4,084

Most-cited papers

Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation.
N. Breet, J. V. van Werkum, H. Bouman, J. Kelder +9 more
2010Journal of the American Medical Association (JAMA)875 citations
Semantic Scholar
Surfactant protein C mutations are the basis of a significant portion of adult familial pulmonary fibrosis in a dutch cohort.
C. V. van Moorsel, M. V. van Oosterhout, N. Barlo, Pim A. de Jong +5 more
2010American Journal of Respiratory and Critical Care Medicine279 citations
Semantic Scholar
CYP2C19*2 and CYP2C9*3 alleles are associated with stent thrombosis: a case-control study.
A. Harmsze, J. V. van Werkum, J. T. ten Berg, B. Zwart +8 more
2010European Heart Journal163 citations
Semantic Scholar
Serum and BALF YKL-40 levels are predictors of survival in idiopathic pulmonary fibrosis.
N. Korthagen, C. V. van Moorsel, N. Barlo, H. Ruven +4 more
2011Respiratory Medicine126 citations Open access
Semantic Scholar
ACE and sIL-2R correlate with lung function improvement in sarcoidosis during methotrexate therapy.
A. Vorselaars, C. V. van Moorsel, P. Zanen, H. Ruven +3 more
2015Respiratory Medicine112 citations Open access
Semantic Scholar
C-C chemokine receptor 2 and sarcoidosis: association with Lofgren's syndrome.
P. Spagnolo, E. Renzoni, A. Wells, H. Sato +7 more
2003American Journal of Respiratory and Critical Care Medicine107 citations
Semantic Scholar
Transforming growth factor-beta gene polymorphisms in sarcoidosis patients with and without fibrosis.
A. Kruit, J. Grutters, H. Ruven, C. V. van Moorsel +3 more
2006Chest99 citations
Semantic Scholar
Bronchoalveolar lavage cell pattern from healthy human lung
M. Heron, J. Grutters, K. M. ten Dam-Molenkamp, D. Hijdra +5 more
2012Clinical and Experimental Immunology96 citations Open access
Semantic Scholar
18F-FDG PET, genotype-corrected ACE and sIL-2R in newly diagnosed sarcoidosis
R. Keijsers, F. Verzijlbergen, W. Oyen, J. van den Bosch +3 more
2009European Journal of Nuclear Medicine and Molecular Imaging92 citations
Semantic Scholar
Atopy and new‐onset asthma in young Danish farmers and CD14, TLR2, and TLR4 genetic polymorphisms: a nested case‐control study
L. Smit, S. Bongers, H. Ruven, G. Rijkers +4 more
2007Clinical and Experimental Allergy92 citations Open access
Semantic Scholar
Surfactant protein-D predicts survival in patients with idiopathic pulmonary fibrosis.
N. Barlo, C. V. van Moorsel, H. Ruven, P. Zanen +2 more
2009Sarcoidosis Vasculities and Diffuse Lung Diseases91 citations
Semantic Scholar
ACE I/D-corrected Z-scores to identify normal and elevated ACE activity in sarcoidosis.
A. Kruit, J. Grutters, W. Gerritsen, S. Kos +3 more
2007Respiratory Medicine91 citations Open access
Semantic Scholar
Linkage between Toll‐like receptor (TLR) 2 promotor and intron polymorphisms: functional effects and relevance to sarcoidosis
M. Veltkamp, P. Wijnen, C. V. van Moorsel, G. Rijkers +7 more
2007Clinical and Experimental Immunology90 citations Open access
Semantic Scholar
The use of amlodipine, but not of P-glycoprotein inhibiting calcium channel blockers is associated with clopidogrel poor-response
A. Harmsze, K. Robijns, J. V. van Werkum, N. Breet +6 more
2010Thrombosis and Haemostasis89 citations
Semantic Scholar
A CHI3L1 gene polymorphism is associated with serum levels of YKL-40, a novel sarcoidosis marker.
A. Kruit, J. Grutters, H. Ruven, C. V. van Moorsel +1 more
2007Respiratory Medicine81 citations Open access
Semantic Scholar
Analysis of BTNL2 genetic polymorphisms in British and Dutch patients with sarcoidosis.
P. Spagnolo, H. Sato, J. Grutters, E. Renzoni +8 more
2007Tissue Antigens80 citations Open access
Semantic Scholar
The influence of CYP2C19*2 and *17 on on-treatment platelet reactivity and bleeding events in patients undergoing elective coronary stenting
A. Harmsze, J. V. van Werkum, C. Hackeng, H. Ruven +7 more
2012Pharmacogenetics & Genomics79 citations
Semantic Scholar
SFTPA2 Mutations in Familial and Sporadic Idiopathic Interstitial Pneumonia.
C. V. van Moorsel, L. ten Klooster, M. V. van Oosterhout, Pim A. de Jong +5 more
2015American Journal of Respiratory and Critical Care Medicine74 citations Open access
Semantic Scholar
Genetic variability in the IL1RN gene and the balance between interleukin (IL)‐1 receptor agonist and IL‐1β in idiopathic pulmonary fibrosis
N. Barlo, C. V. van Moorsel, N. Korthagen, M. Heron +4 more
2011Clinical and Experimental Immunology74 citations Open access
Semantic Scholar
Toll-like Receptor 2 Polymorphism Is Associated With Preterm Birth
T. Krediet, S. Wiertsema, Marjolein Vossers, S. Hoeks +3 more
2007Pediatric Research73 citations
Semantic Scholar
Functional polymorphisms in the mannan-binding lectin 2 gene: effect on MBL levels and otitis media.
S. Wiertsema, B. Herpers, R. Veenhoven, M. Salimans +3 more
2006Journal of Allergy and Clinical Immunology71 citations
Semantic Scholar
Genetic variation in the Toll-like receptor gene cluster (TLR10-TLR1-TLR6) influences disease course in sarcoidosis.
M. Veltkamp, C. V. van Moorsel, G. Rijkers, H. Ruven +1 more
2012Tissue Antigens67 citations
Semantic Scholar
IL1RN genetic variations and risk of IPF: a meta-analysis and mRNA expression study
N. Korthagen, C. V. van Moorsel, K. Kazemier, H. Ruven +1 more
2012Immunogenetics62 citations Open access
Semantic Scholar
Disease modifying genes in cystic fibrosis.
M. Slieker, E. Sanders, G. Rijkers, H. Ruven +1 more
2005Journal of Cystic Fibrosis60 citations Open access
Semantic Scholar
Association between Variations in Cell Cycle Genes and Idiopathic Pulmonary Fibrosis
N. Korthagen, C. V. van Moorsel, N. Barlo, K. Kazemier +2 more
2012PLoS ONE54 citations Open access
Semantic Scholar
Genetic variation in GREM1 is a risk factor for fibrosis in pulmonary sarcoidosis.
M. Heron, C. V. van Moorsel, J. Grutters, T. Huizinga +4 more
2011Tissue Antigens51 citations
Semantic Scholar
Polymorphisms in innate immunity genes associated with development of bronchiolitis obliterans after lung transplantation.
E. A. Kastelijn, C. V. van Moorsel, G. Rijkers, H. Ruven +7 more
2010The Journal of Heart and Lung Transplantation49 citations
Semantic Scholar
Variation in IL7R predisposes to sarcoid inflammation
M. Heron, J. Grutters, C. V. van Moorsel, H. Ruven +4 more
2009Genes and Immunity48 citations Open access
Semantic Scholar
CA 15-3 as an alternative marker for KL-6 in fibrotic lung diseases.
A. Kruit, W. Gerritsen, N. Pot, J. Grutters +2 more
2010Sarcoidosis Vasculities and Diffuse Lung Diseases47 citations
Semantic Scholar
The Fcγ Receptor IIA-R/R131 Genotype Is Associated with Severe Sepsis in Community-Acquired Pneumonia
H. Endeman, M. Cornips, J. Grutters, J. van den Bosch +4 more
2009Clinical and Vaccine Immunology44 citations Open access
Semantic Scholar
Inhibitor kappa B-alpha (IκB-α) promoter polymorphisms in UK and Dutch sarcoidosis
A. Abdallah, H. Sato, J. Grutters, S. Veeraraghavan +6 more
2003Genes and Immunity44 citations Open access
Semantic Scholar
Toll‐like receptor (TLR) 4 polymorphism Asp299Gly is not associated with disease course in Dutch sarcoidosis patients
M. Veltkamp, J. Grutters, C. V. van Moorsel, H. Ruven +1 more
2006Clinical and Experimental Immunology40 citations Open access
Semantic Scholar
Evaluation of Circulating YKL-40 Levels in Idiopathic Interstitial Pneumonias
N. Korthagen, C. V. van Moorsel, P. Zanen, H. Ruven +1 more
2014Lung38 citations
Semantic Scholar
Toll‐like receptor (TLR)‐9 genetics and function in sarcoidosis
M. Veltkamp, C. V. van Moorsel, G. Rijkers, H. Ruven +2 more
2010Clinical and Experimental Immunology37 citations Open access
Semantic Scholar
Analysis of IL6 and IL1A gene polymorphisms in UK and Dutch patients with sarcoidosis.
J. Grutters, H. Sato, P. Pantelidis, H. Ruven +5 more
2003Sarcoidosis Vasculities and Diffuse Lung Diseases37 citations
Semantic Scholar
Association between serum biomarkers CEA and LDH and response in advanced non‐small cell lung cancer patients treated with platinum‐based chemotherapy
C. de Jong, V. Deneer, J. Kelder, H. Ruven +2 more
2020Thoracic Cancer35 citations Open access
Semantic Scholar
The mucin-1 568 adenosine to guanine polymorphism influences serum Krebs von den Lungen-6 levels.
Rob Janssen, A. Kruit, J. Grutters, H. Ruven +2 more
2006American Journal of Respiratory Cell and Molecular Biology35 citations
Semantic Scholar
The MUC5B Promotor Polymorphism Associates with Severe COVID-19 in the European Population
C. V. van Moorsel, J. J. van der Vis, C. Benschop, D. Ellinghaus +5 more
2020Social Science Research Network31 citations Open access
Semantic Scholar
Inhibitor kappa B-alpha (IkappaB-alpha) promoter polymorphisms in UK and Dutch sarcoidosis.
A. Abdallah, H. Sato, J. Grutters, S. Veeraraghavan +6 more
2003Genes and Immunity31 citations
Semantic Scholar
Genetic Variation in CCL18 Gene Influences CCL18 Expression and Correlates with Survival in Idiopathic Pulmonary Fibrosis: Part A
I. Wiertz, S. A. Moll, B. Seeliger, N. Barlo +7 more
2020Journal of Clinical Medicine29 citations Open access
Semantic Scholar
No association between interleukin-18 gene polymorphisms and haplotypes in Dutch sarcoidosis patients.
Rob Janssen, J. Grutters, H. Ruven, P. Zanen +4 more
2004Tissue Antigens24 citations
Semantic Scholar
Genetic polymorphisms in MMP7 and reduced serum levels associate with the development of bronchiolitis obliterans syndrome after lung transplantation.
E. A. Kastelijn, C. V. van Moorsel, H. Ruven, V. Karthaus +6 more
2010The Journal of Heart and Lung Transplantation22 citations
Semantic Scholar
Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism.
M. Beckers, H. Ruven, F. Haas, P. Doevendans +3 more
2010European journal of internal medicine19 citations
Semantic Scholar
The influence of variation in the P2Y12 receptor gene on in vitro platelet inhibition with the direct P2Y12 antagonist cangrelor
H. Bouman, J. V. van Werkum, Goran Rude, F. Leebeek +5 more
2009Thrombosis and Haemostasis19 citations
Semantic Scholar
Angiotensin-converting enzyme insertion/deletion polymorphism and risk and outcome of pneumonia.
E. V. D. van de Garde, H. Endeman, V. Deneer, D. Biesma +4 more
2008Chest18 citations Open access
Semantic Scholar
Genetic Polymorphisms and Bronchiolitis Obliterans Syndrome After Lung Transplantation: Promising Results and Recommendations for the Future
E. A. Kastelijn, C. V. van Moorsel, H. Ruven, J. Lammers +1 more
2012Transplantation15 citations Open access
Semantic Scholar
A genetic polymorphism in the CAV1 gene associates with the development of bronchiolitis obliterans syndrome after lung transplantation
E. A. Kastelijn, C. V. van Moorsel, K. Kazemier, S. Roothaan +6 more
2011Fibrogenesis & Tissue Repair15 citations Open access
Semantic Scholar
Angiotensin II receptor type 1 1166 A/C and angiotensin converting enzyme I/D gene polymorphisms in a Dutch sarcoidosis cohort.
A. Kruit, H. Ruven, J. Grutters, J. van den Bosch
2010Sarcoidosis Vasculities and Diffuse Lung Diseases14 citations
Semantic Scholar
Effect of variation in ITGAE on risk of sarcoidosis, CD103 expression, and chest radiography.
M. Heron, J. Grutters, C. V. van Moorsel, H. Ruven +3 more
2009Clinical Immunology14 citations
Semantic Scholar
No influence of heparin plasma and other (pre)analytic variables on D-dimer determinations.
R. Schutgens, F. Haas, H. Ruven, M. Spannagl +2 more
2002Clinical Chemistry14 citations
Semantic Scholar

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