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Irene Bighelli · SciRah

Researcher profile · Semantic Scholar

Irene Bighelli

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Irene Bighelli — researcher profile on SciRah

h-index: 31
Works: 100
Citations: 7,815

Most-cited papers

What is the European Medicines Agency?
Irene Bighelli, C. Barbui
2012Epidemiology and Psychiatric Sciences4,469 citations Open access
Semantic Scholar
Psychosocial and psychological interventions for relapse prevention in schizophrenia: a systematic review and network meta-analysis.
Irene Bighelli, Alessandro Rodolico, H. García-Mieres, G. Pitschel-Walz +9 more
2021Lancet psychiatry230 citations Open access
Semantic Scholar
Psychosocial interventions for post-traumatic stress disorder in refugees and asylum seekers resettled in high-income countries: Systematic review and meta-analysis
M. Nosè, F. Ballette, Irene Bighelli, G. Turrini +4 more
2017PLoS ONE221 citations Open access
Semantic Scholar
Antipsychotic drugs for patients with schizophrenia and predominant or prominent negative symptoms: a systematic review and meta-analysis
M. Krause, Yi-Kang Zhu, M. Huhn, J. Schneider-Thoma +3 more
2018European Archives of Psychiatry and Clinical Neuroscience217 citations Open access
Semantic Scholar
Comparative efficacy and tolerability of 32 oral and long-acting injectable antipsychotics for the maintenance treatment of adults with schizophrenia: a systematic review and network meta-analysis.
J. Schneider-Thoma, K. Chalkou, Carola Dörries, Irene Bighelli +8 more
2022The Lancet173 citations Open access
Semantic Scholar
Psychological interventions to reduce positive symptoms in schizophrenia: systematic review and network meta‐analysis
Irene Bighelli, G. Salanti, M. Huhn, J. Schneider-Thoma +8 more
2018World Psychiatry168 citations Open access
Semantic Scholar
Online Training and Support Programs Designed to Improve Mental Health and Reduce Burden Among Caregivers of People With Dementia: A Systematic Review.
K. Egan, Ángel C Pinto-Bruno, Irene Bighelli, M. Berg-Weger +3 more
2018Journal of the American Medical Directors Association147 citations Open access
Semantic Scholar
How well do patients with a first episode of schizophrenia respond to antipsychotics: A systematic review and meta-analysis.
Yi-Kang Zhu, Chun-Bo Li, M. Huhn, Philipp H Rothe +4 more
2017European Neuropsychopharmacology142 citations
Semantic Scholar
Efficacy, acceptability, and tolerability of antipsychotics in children and adolescents with schizophrenia: A network meta-analysis.
M. Krause, Yi-Kang Zhu, M. Huhn, J. Schneider-Thoma +3 more
2017European Neuropsychopharmacology123 citations
Semantic Scholar
Family interventions for relapse prevention in schizophrenia: a systematic review and network meta-analysis.
Alessandro Rodolico, Irene Bighelli, C. Avanzato, C. Concerto +11 more
2022Lancet psychiatry118 citations
Semantic Scholar
Pharmacological and dietary-supplement treatments for autism spectrum disorder: a systematic review and network meta-analysis
S. Siafis, Oğulcan Çıray, Hui Wu, J. Schneider-Thoma +14 more
2022Molecular Autism113 citations Open access
Semantic Scholar
Metabolic side effects in persons with schizophrenia during mid‐ to long‐term treatment with antipsychotics: a network meta‐analysis of randomized controlled trials
Angelika Burschinski, J. Schneider-Thoma, V. Chiocchia, Kristina Schestag +9 more
2023World Psychiatry99 citations Open access
Semantic Scholar
Antipsychotic Drugs and Cognitive Function: A Systematic Review and Pairwise Network Meta-Analysis.
le J. Feber, N. Peter, V. Chiocchia, J. Schneider-Thoma +9 more
2024JAMA psychiatry94 citations Open access
Semantic Scholar
The Impact of the COVID-19 Pandemic and Associated Control Measures on the Mental Health of the General Population
G. Salanti, N. Peter, T. Tonia, A. Holloway +68 more
2022Annals of Internal Medicine91 citations Open access
Semantic Scholar
Does formulation matter? A systematic review and meta-analysis of oral versus long-acting antipsychotic studies.
G. Ostuzzi, Irene Bighelli, R. So, T. Furukawa +1 more
2017Schizophrenia Research78 citations
Semantic Scholar
Efficacy, acceptability and tolerability of antipsychotics in patients with schizophrenia and comorbid substance use. A systematic review and meta-analysis.
M. Krause, M. Huhn, J. Schneider-Thoma, Irene Bighelli +2 more
2019European Neuropsychopharmacology72 citations
Semantic Scholar
A network meta-analysis of efficacy, acceptability, and tolerability of antipsychotics in treatment-resistant schizophrenia
Shi-Meng Dong, J. Schneider-Thoma, Irene Bighelli, S. Siafis +5 more
2023European Archives of Psychiatry and Clinical Neuroscience64 citations Open access
Semantic Scholar
Antidepressants versus placebo for panic disorder in adults.
Irene Bighelli, Mariasole Castellazzi, A. Cipriani, F. Girlanda +5 more
2013Cochrane Database of Systematic Reviews61 citations Open access
Semantic Scholar
How well do elderly patients with major depressive disorder respond to antidepressants: a systematic review and single-group meta-analysis
Katharina Gutsmiedl, M. Krause, Irene Bighelli, J. Schneider-Thoma +1 more
2020BMC Psychiatry60 citations Open access
Semantic Scholar
Placebo response in pharmacological and dietary supplement trials of autism spectrum disorder (ASD): systematic review and meta-regression analysis
S. Siafis, Oğulcan Çıray, J. Schneider-Thoma, Irene Bighelli +12 more
2020Molecular Autism59 citations Open access
Semantic Scholar
Benzodiazepines versus placebo for panic disorder in adults.
Johanna Breilmann, F. Girlanda, G. Guaiana, C. Barbui +6 more
2013Cochrane Database of Systematic Reviews58 citations Open access
Semantic Scholar
Efficacy and tolerability of pharmacological and non-pharmacological interventions in older patients with major depressive disorder: A systematic review, pairwise and network meta-analysis.
M. Krause, Katharina Gutsmiedl, Irene Bighelli, J. Schneider-Thoma +2 more
2019European Neuropsychopharmacology56 citations Open access
Semantic Scholar
Antipsychotic Dose Mediates the Association between Polypharmacy and Corrected QT Interval
C. Barbui, Irene Bighelli, G. Carrà, Mariasole Castellazzi +4 more
2016PLoS ONE56 citations Open access
Semantic Scholar
Combinations of QTc-prolonging drugs: towards disentangling pharmacokinetic and pharmacodynamic effects in their potentially additive nature
A. Meid, Irene Bighelli, S. Mächler, G. Mikus +8 more
2017Therapeutic Advances in Psychopharmacology52 citations Open access
Semantic Scholar
Prevalence and correlates of QTc prolongation in Italian psychiatric care: cross-sectional multicentre study
M. Nosè, Irene Bighelli, Mariasole Castellazzi, G. Martinotti +91 more
2015Epidemiology and Psychiatric Sciences48 citations Open access
Semantic Scholar
Response rates in patients with schizophrenia and positive symptoms receiving cognitive behavioural therapy: a systematic review and single-group meta-analysis
Irene Bighelli, M. Huhn, J. Schneider-Thoma, M. Krause +7 more
2018BMC Psychiatry46 citations Open access
Semantic Scholar
Antidepressants and benzodiazepines for panic disorder in adults.
Irene Bighelli, Carlotta Trespidi, Mariasole Castellazzi, A. Cipriani +5 more
2016Cochrane Database of Systematic Reviews42 citations Open access
Semantic Scholar
Psychological and psychosocial interventions for treatment-resistant schizophrenia: a systematic review and network meta-analysis.
Nurul Husna Salahuddin, Alexandra Schütz, Gabi Pitschel-Walz, Susanna Franziska Mayer +5 more
2024Lancet psychiatry39 citations Open access
Semantic Scholar
Second-generation antipsychotic drugs and short-term somatic serious adverse events: a systematic review and meta-analysis.
J. Schneider-Thoma, O. Efthimiou, Irene Bighelli, Carola Dörries +7 more
2019Lancet psychiatry36 citations Open access
Semantic Scholar
Effectiveness of lithium in subjects with treatment-resistant depression and suicide risk: results and lessons of an underpowered randomised clinical trial
F. Girlanda, A. Cipriani, E. Agrimi, Maria Grazia Appino +42 more
2014BMC Research Notes33 citations Open access
Semantic Scholar
Effects of psychological treatments on functioning in people with Schizophrenia: a systematic review and meta-analysis of randomized controlled trials
Irene Bighelli, Sofia Wallis, Cornelia Reitmeir, Felicitas Schwermann +2 more
2022European Archives of Psychiatry and Clinical Neuroscience32 citations Open access
Semantic Scholar
Antipsychotic dose reduction compared to dose continuation for people with schizophrenia
Alessandro Rodolico, S. Siafis, Irene Bighelli, M. Samara +7 more
2022Cochrane Database of Systematic Reviews29 citations Open access
Semantic Scholar
First‐generation antipsychotics and QTc: any role for mediating variables?
G. Carrà, C. Crocamo, F. Bartoli, A. Lax +9 more
2016Human psychopharmacology27 citations
Semantic Scholar
Azapirones versus placebo for panic disorder in adults.
H. Imai, A. Tajika, Peiyao Chen, A. Pompoli +8 more
2014Cochrane Database of Systematic Reviews24 citations Open access
Semantic Scholar
Efficacy of clozapine versus second-generation antipsychotics in people with treatment-resistant schizophrenia: a systematic review and individual patient data meta-analysis.
J. Schneider-Thoma, T. Hamza, K. Chalkou, S. Siafis +20 more
2025Lancet psychiatry22 citations Open access
Semantic Scholar
Are Randomized Controlled Trials on Pharmacotherapy and Psychotherapy for Positive Symptoms of Schizophrenia Comparable? A Systematic Review of Patient and Study Characteristics.
Irene Bighelli, C. Leucht, M. Huhn, Cornelia Reitmeir +4 more
2019Schizophrenia bulletin21 citations Open access
Semantic Scholar
Information needs of female Italian breast cancer patients during their first oncological consultation.
C. Goss, G. Deledda, Alessandro Bottacini, F. Chiodera +6 more
2015European Journal of Oncology Nursing21 citations
Semantic Scholar
INvolvement of breast CAncer patients during oncological consultations: a multicentre randomised controlled trial—the INCA study protocol
C. Goss, A. Ghilardi, G. Deledda, C. Buizza +19 more
2013BMJ Open21 citations Open access
Semantic Scholar
Relapse in clinically stable adult patients with schizophrenia or schizoaffective disorder: evidence-based criteria derived by equipercentile linking and diagnostic test accuracy meta-analysis.
S. Siafis, L. Brandt, R. McCutcheon, Stefan Gutwinski +22 more
2023Lancet psychiatry20 citations
Semantic Scholar
Pharmacological treatments in panic disorder in adults: a network meta-analysis
G. Guaiana, C. Barbui, N. Meader, S. Davies +9 more
2020Cochrane Database of Systematic Reviews19 citations Open access
Semantic Scholar
The controversy about cognitive behavioural therapy for schizophrenia
P. Mckenna, S. Leucht, S. Jauhar, K. Laws +1 more
2019World Psychiatry19 citations Open access
Semantic Scholar
Effectiveness of lithium in subjects with treatment-resistant depression and suicide risk: a protocol for a randomised, independent, pragmatic, multicentre, parallel-group, superiority clinical trial
A. Cipriani, F. Girlanda, E. Agrimi, A. Barichello +39 more
2013BMC Psychiatry19 citations Open access
Semantic Scholar
How Efficacious Are Antipsychotic Drugs for Schizophrenia? An Interpretation Based on 13 Effect Size Indices.
S. Leucht, S. Siafis, R. Engel, J. Schneider-Thoma +4 more
2021Schizophrenia bulletin18 citations Open access
Semantic Scholar
Antipsychotic polypharmacy reduction versus polypharmacy continuation for people with schizophrenia
Irene Bighelli, Alessandro Rodolico, S. Siafis, M. Samara +7 more
2021Cochrane Database of Systematic Reviews18 citations Open access
Semantic Scholar
Short-acting intramuscular second-generation antipsychotic drugs for acutely agitated patients with schizophrenia spectrum disorders. A systematic review and network meta-analysis.
Giulia Paris, Irene Bighelli, G. Deste, S. Siafis +5 more
2021Schizophrenia Research18 citations
Semantic Scholar
A New Approach to Psychiatric Drug Approval in Europe
C. Barbui, Irene Bighelli
2013PLoS Medicine17 citations Open access
Semantic Scholar
Comparative efficacy and tolerability of antidopaminergic and muscarinic antipsychotics for acute schizophrenia: a network meta-analysis of randomised controlled trials indexed in international English and Chinese databases.
J. Schneider-Thoma, Yi-Kang Zhu, Mengchang Qin, Yujie Dong +17 more
2026The Lancet15 citations Open access
Semantic Scholar
Oral versus long-acting injectable antipsychotics in schizophrenia spectrum disorders: A systematic review of patients' subjective experiences.
S. F. Aprile, Alessandro Rodolico, A. Di Francesco, S. Varrasi +5 more
2025Psychiatry Research15 citations Open access
Semantic Scholar
Antipsychotic drugs and their effects on cognitive function: protocol for a systematic review, pairwise, and network meta-analysis
le J. Feber, N. Peter, J. Schneider-Thoma, S. Siafis +7 more
2023Systematic Reviews15 citations Open access
Semantic Scholar
Metabolic side effects of antipsychotic drugs in individuals with schizophrenia during medium- to long-term treatment: protocol for a systematic review and network meta-analysis of randomized controlled trials
J. Schneider-Thoma, A. Kapfhammer, Dongfang Wang, Irene Bighelli +6 more
2021Systematic Reviews15 citations Open access
Semantic Scholar

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