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R. Aplenc · SciRah

Researcher profile · Semantic Scholar

R. Aplenc

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R. Aplenc — researcher profile on SciRah

h-index: 60
Works: 580
Citations: 22K

Most-cited papers

CYTOKINE-MEDIATED CAR T THERAPY RESISTANCE IN AML
Anand S. Bhagwat, L. Torres, O. Shestova, M. Shestov +25 more
2024Nature Medicine97 citations Open access
Semantic Scholar
Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies
J. Jadlowsky, E. Hexner, A. Marshall, S. Grupp +62 more
2025Nature Medicine86 citations
Semantic Scholar
Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia
E. J. Bertrums, Jenny L. Smith, L. Harmon, R. Ries +33 more
2023Haematologica75 citations Open access
Semantic Scholar
CD38 as a pan-hematologic target for chimeric antigen receptor T cells
Tina Glisovic-Aplenc, C. Diorio, J. Chukinas, Kimberly Veliz +11 more
2023Blood Advances64 citations Open access
Semantic Scholar
Dexrazoxane and Long-Term Heart Function in Survivors of Childhood Cancer
Eric J. Chow, S. Aggarwal, D. Doody, R. Aplenc +15 more
2023Journal of Clinical Oncology61 citations Open access
Semantic Scholar
Diagnosis and Management of AML in Pediatric Patients: Consensus Recommendations from an International Expert Panel.
C. Zwaan, Sarah K. Tasian, R. Aplenc, L. Brodersen +21 more
2025Blood34 citations Open access
Semantic Scholar
Reinfusion of CD19 CAR T cells for relapse prevention and treatment in children with acute lymphoblastic leukemia
Regina M. Myers, Kaitlin J. Devine, Yi-Mei Li, Sophie Lawrence +19 more
2024Blood Advances30 citations Open access
Semantic Scholar
Optimized cytogenetic risk-group stratification of KMT2A-rearranged pediatric acute myeloid leukemia
Romy E. van Weelderen, C. Harrison, K. Klein, Yi-Li Jiang +31 more
2024Blood Advances30 citations Open access
Semantic Scholar
Pathologic, Cytogenetic, and Molecular Features of Acute Myeloid Leukemia with Megakaryocytic Differentiation: a Report from the Children’s Oncology Group
Karen M. Chisholm, Jenny L. Smith, Amy E Heerema-McKenney, J. Choi +11 more
2023Pediatric Blood & Cancer30 citations Open access
Semantic Scholar
Epigenomic diagnosis and prognosis of Acute Myeloid Leukemia
Francisco Marchi, Vivek M. Shastri, Richard J. Marrero, Nam H. K. Nguyen +25 more
2025Nature Communications20 citations Open access
Semantic Scholar
CD22-targeted chimeric antigen receptor-modified T cells for children and adults with relapse of B-cell acute lymphoblastic leukemia after CD19-directed immunotherapy
Regina M. Myers, Amanda M. DiNofia, Yi-Mei Li, C. Diorio +25 more
2025Journal for ImmunoTherapy of Cancer20 citations Open access
Semantic Scholar
Prognostic impact of cooccurring mutations in FLT3-ITD pediatric acute myeloid leukemia
Katherine Tarlock, R. Gerbing, R. Ries, Jenny L. Smith +13 more
2024Blood Advances17 citations Open access
Semantic Scholar
A Phase 3 Randomized Trial for Patients with De Novo AML Comparing Standard Therapy Including Gemtuzumab Ozogamicin (GO) to CPX-351 with GO - a Report from the Children's Oncology Group
J. Pollard, T. Alonzo, R. Gerbing, M. Kutny +22 more
2024Blood13 citations
Semantic Scholar
CD74 is expressed in a subset of pediatric acute myeloid leukemia patients and is a promising target for therapy: a report from the Children’s Oncology Group
Andrew J. Menssen, Chad A. Hudson, T. Alonzo, R. Gerbing +19 more
2024Haematologica13 citations Open access
Semantic Scholar
Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia
O. Abla, R. Ries, T. Triche, R. Gerbing +13 more
2024Blood Advances13 citations Open access
Semantic Scholar
International consensus guidelines for the conduct and reporting of CAR T-cell clinical trials in AML
Swati Naik, R. Aplenc, Susanne H. Baumeister, M. Becilli +31 more
2025Blood Advances9 citations
Semantic Scholar
Automated Electronic Health Record Data Extraction and Curation Using ExtractEHR
Tamara P. Miller, K. Getz, Edward M. Krause, Gun-Jo Yun +7 more
2024JCO Clinical Cancer Informatics9 citations Open access
Semantic Scholar
SAMHD1 single nucleotide polymorphisms impact outcome in children with newly diagnosed acute myeloid leukemia
Richard J. Marrero, Xueyuan Cao, Hui-Yun Wu, Abdelrahman H. Elsayed +11 more
2023Blood Advances9 citations Open access
Semantic Scholar
Cardiotoxicity of CPX-351 in children and adolescents with relapsed AML: a Children's Oncology Group report
Kasey J. Leger, M. Absalon, B. Demissei, Amanda M. Smith +11 more
2024Frontiers in Cardiovascular Medicine7 citations Open access
Semantic Scholar
Integrated drug resistance and leukemic stemness gene-expression scores predict outcomes in large cohort of over 3500 AML patients from 10 trials
Abdelrahman H. Elsayed, Xue-Yuan Cao, Richard J. Marrero, Nam H. K. Nguyen +17 more
2024npj Precision Oncology7 citations Open access
Semantic Scholar
Therapies and outcomes following extramedullary relapse of pediatric and young adult ALL after CD19 CAR T-cell therapy
Barbara D Friedes, Amanda M. DiNofia, Emma Iannone, Yi-Mei Li +11 more
2024Blood Advances7 citations Open access
Semantic Scholar
CD19 CAR T cell therapy is an effective strategy for first CNS relapse in pediatric b ALL
Amanda M. DiNofia, Regina M. Myers, Yimei Li, Hongyan Liu +23 more
2025Blood6 citations
Semantic Scholar
Absolute neutrophil count clinical trial eligibility criteria for pediatric oncology phase I and phase I/II trials by sponsorship
Jenny Ruiz, Rebecca K Kelly, R. Aplenc, T. Laetsch +1 more
2024Pediatric Blood & Cancer5 citations Open access
Semantic Scholar
Chromatin Profiles Are Prognostic of Clinical Response to Bortezomib-Containing Chemotherapy in Pediatric Acute Myeloid Leukemia: Results from the COG AAML1031 Trial
Anneke D. van Dijk, F. Hoff, Yi-Hua Qiu, Stefan E. Hubner +12 more
2024Cancers4 citations Open access
Semantic Scholar
Child and family perceptions of satisfaction with neutropenia management in pediatric acute myeloid leukemia
J. Szymczak, K. Getz, Rachel Madding, Sydney Shuster +10 more
2023Pediatric Blood & Cancer4 citations Open access
Semantic Scholar
Combining menin and MEK inhibition to target poor prognosis KMT2A-rearranged RAS pathway–mutant acute myeloid leukemia
N. Scheidegger, C. Schneider, G. Alexe, Yi-Cheng Wang +19 more
2026Blood Advances3 citations Open access
Semantic Scholar
Cytarabine Pharmacogenomics and Outcomes Among Children and Young Adults With Acute Myeloid Leukemia
Richard J. Marrero, Vivek M. Shastri, D. Nicolet, K. Mrózek +20 more
2025JAMA Network Open3 citations Open access
Semantic Scholar
Protocol for plasma membrane enrichment by ultracentrifugation for mass spectrometry of cell lines, xenografts, and patient tumors
Amber K. Hamilton, Brian Mooney, Tina Glisovic-Aplenc, Alexander Radaoui +9 more
2025STAR Protocols3 citations
Semantic Scholar
Long-read epigenomic diagnosis and prognosis of Acute Myeloid Leukemia
J. Lamba, Francisco Marchi, Marieke Landwehr, Ann-Kathrin Schade +22 more
2024Research Square3 citations
Semantic Scholar
Household income and health‐related quality of life in children receiving treatment for acute myeloid leukemia: Potential impact of selection bias in health equity research
H. Newman, Yi-Mei Li, Yuan-Shung V. Huang, Caitlin W. Elgarten +20 more
2024Cancer Medicine3 citations Open access
Semantic Scholar
Success of Centralized Manufacturing of CD33 CAR T-Cells (CD33CART) for Children and Young Adults with Relapsed/Refractory AML
B. Bowser, Xiaoyin Yang, John Roach, Julie Blake +21 more
2024Transplantation and Cellular Therapy3 citations Open access
Semantic Scholar
Neurocognitive impairment and financial hardship in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study
Daniel Zheng, Shalini Bhatia, Sedigheh Mirzaei, R. Aplenc +15 more
2026Journal of the National Cancer Institute2 citations Open access
Semantic Scholar
Etoposide can be safely removed from induction chemotherapy without impacting survival for pediatric acute myeloid leukemia – a report from the Children's oncology group study AAML1831
J. Rossoff, Jing Chen, T. Alonzo, Jim Wang +10 more
2025Blood2 citations
Semantic Scholar
Humanized CD19 chimeric antigen receptor (CAR) T-cell therapy for high-risk and post-CAR relapse of B-cell acute lymphoblastic leukemia
Lucy E. Cain, Yimei Li, Hongyan Liu, Shannon Christensen +29 more
2025Blood2 citations
Semantic Scholar
Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia.
H. Newman, Shawna Lee, P. Pölönen, R. Shraim +38 more
2025Blood Cancer Discovery2 citations
Semantic Scholar
CD123-directed chimeric antigen receptor T-cell (CART123) therapy for relapsed/refractory pediatric acute myeloid leukemia
Lucy E. Cain, Yimei Li, Anand S. Bhagwat, D. Baniewicz +24 more
2025Blood2 citations
Semantic Scholar
Identification of single-cell blasts in pediatric acute myeloid leukemia using an autoencoder
Alice Driessen, Susanne Unger, An-phi Nguyen, R. Ries +8 more
2024Life Science Alliance2 citations Open access
Semantic Scholar
Characteristics and treatment of acute myeloid neoplasms with cutaneous involvement in infants up to 6 months of age: A retrospective study
J. Renaud, B. Goemans, F. Locatelli, M. Pigazzi +10 more
2024Pediatric Blood & Cancer2 citations Open access
Semantic Scholar
INSPIRED Symposium Part 5: Expanding the Use of CAR T cells in Children and Young Adults
A. Talleur, Vanessa A. Fabrizio, R. Aplenc, S. Grupp +6 more
2024Transplantation and Cellular Therapy2 citations Open access
Semantic Scholar
Serum-Based Proteomic Analysis of Cytokine Release Syndrome in Pediatric AML Patients Receiving CART123
Saamia Farooki, Han R Fisher, Anand S. Bhagwat, Tina Glisovic-Aplenc +6 more
2024Blood2 citations
Semantic Scholar
Establishing Real-World Data-Driven Response Criteria in Pediatric Acute Myeloid Leukemia
R. Aplenc, Yi-Mei Li, J. Ani, C. Elgarten +13 more
2023Blood2 citations Open access
Semantic Scholar
AAML1831: A Phase III Trial Comparing Standard Induction Therapy With CPX-351 in De Novo Pediatric AML: A Report From the Children's Oncology Group.
Jessica A. Pollard, T. Alonzo, R. Gerbing, M. Kutny +25 more
2026Journal of Clinical Oncology1 citations
Semantic Scholar
Optimized treatment for pediatric patients with low-risk Acute Myeloid Leukemia: A report from the Children's oncology group study AAML1831
R. Pabari, Chana L. Glasser, T. Alonzo, Jim Wang +12 more
2025Blood1 citations
Semantic Scholar
Optimization of induction chemotherapy in pediatric patients with Acute Myeloid Leukemia: Real-world evidence to support removal of etoposide from induction 1
C. Elgarten, Yimei Li, Yang Xie, Lei Wang +16 more
2025Blood1 citations
Semantic Scholar
Real-world generalizability of clinical trial cytomolecular risk in pediatric acute myeloid leukemia: a report from the REAL-AML cohort
Daniel Zheng, Gary Hettinger, Catherine C. Aftandilian, K. Bona +28 more
2025Journal of the National Cancer Institute1 citations
Semantic Scholar
Fluoroquinolone Susceptibility and Comparative Outcomes of Gram-negative Bloodstream Infection in Pediatric Patients with Hematologic Malignancy.
Eleana Vasileiadi, C. Elgarten, K. Getz, R. Aplenc +1 more
2025Journal of the Pediatric Infectious Diseases Society1 citations
Semantic Scholar
National trends in dexrazoxane and cardiovascular healthcare utilization for children with AML
Daniel Zheng, Gary Hettinger, Jonathan D. Bender, Alexis C Boulter +15 more
2025JAMA Oncology1 citations
Semantic Scholar
Post-transplant maintenance with sorafenib is safe and effective in pediatric patients with har FLT3/ITD AML: A report from the Children's oncology group protocol AAML1031
C. Elgarten, T. Alonzo, R. Gerbing, John Choi +15 more
2025Blood1 citations
Semantic Scholar
Rapid Long-Read Epigenomic Diagnosis and Prognosis of Acute Myeloid Leukemia
Francisco Marchi, Ann-Kathrin Schade, Vivek M. Shastri, Xue-Yuan Cao +11 more
2024Blood1 citations
Semantic Scholar
Applying machine learning to identify pediatric patients with newly diagnosed acute lymphoblastic leukemia using administrative data
Lusha Cao, Yuan-Shung V. Huang, K. Getz, A. Seif +5 more
2024Pediatric Blood & Cancer1 citations
Semantic Scholar

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