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Johannes S. Gach · SciRah

Researcher profile · Semantic Scholar

Johannes S. Gach

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Johannes S. Gach — researcher profile on SciRah

h-index: 19
Works: 59
Citations: 1,813

Most-cited papers

A Limited Number of Antibody Specificities Mediate Broad and Potent Serum Neutralization in Selected HIV-1 Infected Individuals
L. Walker, M. Simek, F. Priddy, Johannes S. Gach +5 more
2010PLoS Pathogens388 citations Open access
Semantic Scholar
Engineering of Pichia pastoris for improved production of antibody fragments
Brigitte Gasser, Michael Maurer, Johannes S. Gach, R. Kunert +1 more
2006Biotechnology and Bioengineering209 citations
Semantic Scholar
Fc-Glycosylation Influences Fcγ Receptor Binding and Cell-Mediated Anti-HIV Activity of Monoclonal Antibody 2G12
D. Forthal, Johannes S. Gach, G. Landucci, Jakub Jeż +3 more
2010Journal of Immunology150 citations
Semantic Scholar
Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface
Li-Kai Song, Zhen-Yu J. Sun, Kate E. Coleman, M. B. Zwick +5 more
2009Proceedings of the National Academy of Sciences of the United States of America136 citations Open access
Semantic Scholar
A Conformational Switch in Human Immunodeficiency Virus gp41 Revealed by the Structures of Overlapping Epitopes Recognized by Neutralizing Antibodies
R. Pejchal, Johannes S. Gach, F. Brunel, R. Cardoso +5 more
2009Journal of Virology99 citations Open access
Semantic Scholar
The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells
Sandeep K. Gupta, Johannes S. Gach, Juan C. Becerra, Tran B. Phan +15 more
2013PLoS Pathogens96 citations Open access
Semantic Scholar
HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition
M. Vaccari, S. Fourati, S. Gordon, Dallas R. Brown +29 more
2018Nature Medicine69 citations Open access
Semantic Scholar
Recent Insights into the HIV/AIDS Pandemic
Juan C. Becerra, L. Bildstein, Johannes S. Gach
2016Microbial Cell60 citations Open access
Semantic Scholar
HIV-specific CD4-induced Antibodies Mediate Broad and Potent Antibody-dependent Cellular Cytotoxicity Activity and are Commonly Detected in Plasma from HIV-infected Humans
K. Williams, V. Cortez, Adam S. Dingens, Johannes S. Gach +6 more
2015EBioMedicine56 citations Open access
Semantic Scholar
Glycan modulation and sulfoengineering of anti–HIV-1 monoclonal antibody PG9 in plants
A. Loos, Johannes S. Gach, T. Hackl, Daniel Maresch +9 more
2015Proceedings of the National Academy of Sciences of the United States of America45 citations Open access
Semantic Scholar
High level expression of a promising anti-idiotypic antibody fragment vaccine against HIV-1 in Pichia pastoris.
Johannes S. Gach, Michael Maurer, R. Hahn, Brigitte Gasser +3 more
2007Journal of Biotechnology41 citations
Semantic Scholar
Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques
A. Verma, B. Schmidt, Sonny R. Elizaldi, Nancy K. Nguyen +18 more
2019Journal of Virology36 citations Open access
Semantic Scholar
Targeting HIV-1 gp41 in close proximity to the membrane using antibody and other molecules.
Johannes S. Gach, D. Leaman, M. B. Zwick
2011Current Topics in Medicinal Chemistry31 citations
Semantic Scholar
Human immunodeficiency virus type-1 (HIV-1) evades antibody-dependent phagocytosis
Johannes S. Gach, M. Bouzin, Marcus P. Wong, Veronika Chromikova +5 more
2017PLoS Pathogens24 citations Open access
Semantic Scholar
HIV-1 Specific Antibody Titers and Neutralization among Chronically Infected Patients on Long-Term Suppressive Antiretroviral Therapy (ART): A Cross-Sectional Study
Johannes S. Gach, C. Achenbach, Veronika Chromikova, B. Berzins +6 more
2014PLoS ONE24 citations Open access
Semantic Scholar
Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce Viral Burden after Heterologous Clade C Simian-Human Immunodeficiency Virus Mucosal Challenge
Delphine C. Malherbe, J. Mendy, L. Vang, Philip Barnette +22 more
2017Journal of Virology23 citations Open access
Semantic Scholar
4E10-Resistant HIV-1 Isolated from Four Subjects with Rare Membrane-Proximal External Region Polymorphisms
Kyle J. Nakamura, Johannes S. Gach, Lori Jones, K. Semrau +12 more
2010PLoS ONE23 citations Open access
Semantic Scholar
A Human Antibody to the CD4 Binding Site of gp120 Capable of Highly Potent but Sporadic Cross Clade Neutralization of Primary HIV-1
Johannes S. Gach, Heribert Quendler, T. Tong, K. Narayan +6 more
2013PLoS ONE21 citations Open access
Semantic Scholar
A genome‐edited N. benthamiana line for industrial‐scale production of recombinant glycoproteins with targeted N‐glycosylation
Benjamin Kogelmann, Stanislav Melnik, Michaela Bogner, Somanath Kallolimath +8 more
2023Biotechnology Journal20 citations Open access
Semantic Scholar
Structure-based design of a protein immunogen that displays an HIV-1 gp41 neutralizing epitope
R. Stanfield, J. Julien, R. Pejchal, Johannes S. Gach +2 more
2011Journal of Molecular Biology19 citations Open access
Semantic Scholar
Synthesis and analysis of the membrane proximal external region epitopes of HIV‐1
Sampat Ingale, Johannes S. Gach, M. B. Zwick, P. Dawson
2010Journal of Peptide Science19 citations
Semantic Scholar
PROLINE IS NOT UNIQUELY CAPABLE OF PROVIDING THE PIVOT POINT FOR DOMAIN SWAPPING IN 2G12, A BROADLY NEUTRALIZING ANTIBODY AGAINST HIV-1
Johannes S. Gach, P. Furtmüller, Heribert Quendler, P. Messner +3 more
2009Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Enhanced in vitro transcytosis of simian immunodeficiency virus mediated by vaccine-induced antibody predicts transmitted/founder strain number after rectal challenge.
Sandeep K. Gupta, P. Pegu, D. Venzon, Johannes S. Gach +5 more
2015Journal of Infectious Diseases14 citations Open access
Semantic Scholar
Validated method for quantification of genetically modified organisms in samples of maize flour.
R. Kunert, Johannes S. Gach, K. Vorauer-Uhl, E. Engel +1 more
2006Journal of Agricultural and Food Chemistry14 citations
Semantic Scholar
Antibody Responses Elicited by Immunization with BG505 Trimer Immune Complexes
Johannes S. Gach, Kane J V Mara, C. Labranche, M. V. van Gils +6 more
2019Journal of Virology13 citations Open access
Semantic Scholar
A High Throughput Protein Microarray Approach to Classify HIV Monoclonal Antibodies and Variant Antigens
Emmanuel Y. Dotsey, A. Gorlani, Sampat Ingale, C. Achenbach +3 more
2015PLoS ONE13 citations Open access
Semantic Scholar
Structural analysis and in vivo administration of an anti-idiotypic antibody against mAb 2F5.
Johannes S. Gach, Heribert Quendler, Stefanie Strobach, H. Katinger +1 more
2008Molecular Immunology13 citations
Semantic Scholar
Partial Humanization and Characterization of an Anti-idiotypic Antibody against Monoclonal Antibody 2F5, a Potential HIV Vaccine?
Johannes S. Gach, Heribert Quendler, R. Weik, H. Katinger +1 more
2007AIDS Research and Human Retroviruses13 citations
Semantic Scholar
Diverse antiviral IgG effector activities are predicted by unique biophysical antibody features
Hao D. Cheng, Karen G. Dowell, Chris Bailey-Kellogg, Brittany A. Goods +10 more
2021Retrovirology11 citations Open access
Semantic Scholar
Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM
Veronika Chromikova, A. Mader, S. Hofbauer, Christoph Göbl +8 more
2015Biochimica et Biophysica Acta10 citations Open access
Semantic Scholar
Correction: The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells
Sandeep K. Gupta, Johannes S. Gach, Juan C. Becerra, Tran B. Phan +15 more
2013PLoS Pathogens10 citations Open access
Semantic Scholar
Expression of a Fab Fragment in CHO and Pichia pastoris A Comparative Case Study
R. Kunert, Johannes S. Gach, H. Katinger
200810 citations
Semantic Scholar
HIV-1-Specific Antibody Response and Function after DNA Prime and Recombinant Adenovirus 5 Boost HIV Vaccine in HIV-Infected Subjects
Johannes S. Gach, A. Gorlani, Emmanuel Y. Dotsey, Juan C. Becerra +12 more
2016PLoS ONE9 citations Open access
Semantic Scholar
SARS-CoV-2 infection of endothelial cells, dependent on flow-induced ACE2 expression, drives hypercytokinemia in a vascularized microphysiological system
Christopher J. Hatch, Sebastian Piombo, Jennifer S. Fang, Johannes S. Gach +6 more
2024Frontiers in Cardiovascular Medicine8 citations Open access
Semantic Scholar
An oligosaccharyltransferase from Leishmania donovani increases the N-glycan occupancy on plant-produced IgG1
Gernot Beihammer, Julia König-Beihammer, Benjamin Kogelmann, Valentina Ruocco +7 more
2023Frontiers in Plant Science7 citations Open access
Semantic Scholar
Vaccination against SARS-CoV-2 using extracellular blebs derived from spike protein-expressing dendritic cells
Jee Y. Chung, Melissa N. Thone, Jenny E. Davies, Johannes S. Gach +3 more
2023Cellular Immunology7 citations Open access
Semantic Scholar
Activity of Monoclonal Antibody 2G12 Binding and Cell-Mediated Anti-HIV Receptor γ Fc-Glycosylation Influences Fc
R. Strasser, R. Kunert, H. Steinkellner, D. Forthal +2 more
20177 citations
Semantic Scholar
Relationship between Vaccine-Induced Antibody Capture of Infectious Virus and Infection Outcomes following Repeated Low-Dose Rectal Challenges with Simian Immunodeficiency Virus SIVmac251
Johannes S. Gach, D. Venzon, M. Vaccari, B. Keele +2 more
2016Journal of Virology7 citations Open access
Semantic Scholar
IgG1 versus IgG3: influence of antibody-specificity and allotypic variance on virus neutralization efficacy
Somanath Kallolimath, Lin Sun, Roman Palt, Esther Föderl-Höbenreich +11 more
2024Frontiers in Immunology6 citations Open access
Semantic Scholar
Virus control in vaccinated rhesus macaques is associated with neutralizing and capturing antibodies against the SHIV challenge virus but not with V1V2 vaccine-induced anti-V2 antibodies alone
A. Hessell, Liuzhe Li, Delphine C. Malherbe, Philip Barnette +17 more
2021Journal of Immunology6 citations Open access
Semantic Scholar
A welcome burst of human antibodies
M. B. Zwick, Johannes S. Gach, D. Burton
2008Nature Biotechnology5 citations Open access
Semantic Scholar
Expression, Purification, and In Vivo Administration of a Promising Anti-Idiotypic HIV-1 Vaccine
Johannes S. Gach, Heribert Quendler, B. Ferko, H. Katinger +1 more
2008Molecular Biotechnology5 citations
Semantic Scholar
In planta expression of active bacterial GDP‐6‐deoxy‐d‐lyxo‐4‐hexulose reductase for glycan modulation
Benjamin Kogelmann, Roman Palt, Daniel Maresch, R. Strasser +8 more
2023Plant Biotechnology Journal4 citations Open access
Semantic Scholar
Internalization of HIV-1 by Phagocytes Is Increased When Virions Are Opsonized with Multimeric Antibody in the Presence of Complement
Johannes S. Gach, Stephanie Y. Matsuno, Mayalen Mercado, Lars Hangartner +1 more
2021Journal of Virology4 citations Open access
Semantic Scholar
Anti-p21 autoantibodies detected in colorectal cancer patients: A proof of concept study
F. Bishehsari, Johannes S. Gach, N. Akagi, Molly K Webber +2 more
2014Oncoimmunology4 citations Open access
Semantic Scholar
S021-05 OA. Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface
Li-Kai Song, Zhen-Yu J. Sun, Kate E. Coleman, M. B. Zwick +5 more
2009Retrovirology4 citations Open access
Semantic Scholar
Neutralizing the threat: harnessing broadly neutralizing antibodies against HIV-1 for treatment and prevention.
Juan C. Becerra, Lauren Hitchcock, Khoa Vu, Johannes S. Gach
2024Microbial Cell3 citations Open access
Semantic Scholar
Detection and Validation of Influenza Virus Hemagglutinin Specific, Cross-Reactive, and Heteroclitic B Cells Induced by a Combination Vaccine Adjuvant
E. Pone, J. Felgner, Jenny E. Hernandez-Davies, Johannes S. Gach +2 more
2025Cytometry Part A1 citations Open access
Semantic Scholar
of CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in
Anil Verma, B. Schmidt, Sonny R. Elizaldi, Nancy K. Nguyen +18 more
20201 citations
Semantic Scholar
Impact of Th1 CD4 TFH skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques
A. Verma, B. Schmidt, Sonny R. Elizaldi, Nancy K. Nguyen +19 more
20191 citations
Semantic Scholar

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