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Purusottam Mohapatra · SciRah

Researcher profile · Semantic Scholar

Purusottam Mohapatra

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Purusottam Mohapatra — researcher profile on SciRah

h-index: 24
Works: 37
Citations: 1,683

Most-cited papers

N-fused imidazoles as novel anticancer agents that inhibit catalytic activity of topoisomerase IIα and induce apoptosis in G1/S phase.
Ashish T. Baviskar, Chetna Madaan, Ranjan Preet, Purusottam Mohapatra +6 more
2011Journal of Medicinal Chemistry270 citations Open access
Semantic Scholar
Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity
Ranjan Preet, Purusottam Mohapatra, Suchitra Mohanty, S. K. Sahu +3 more
2012International Journal of Cancer147 citations Open access
Semantic Scholar
Silver-based nanoparticles induce apoptosis in human colon cancer cells mediated through p53.
S. R. Satapathy, Purusottam Mohapatra, Ranjan Preet, D. Das +4 more
2013Nanomedicine145 citations
Semantic Scholar
Quinacrine-mediated autophagy and apoptosis in colon cancer cells is through a p53- and p21-dependent mechanism.
Purusottam Mohapatra, Ranjan Preet, D. Das, S. R. Satapathy +3 more
2012Oncology Research92 citations Open access
Semantic Scholar
Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC.
Ranjan Preet, Purusottam Mohapatra, D. Das, S. R. Satapathy +3 more
2013Carcinogenesis85 citations
Semantic Scholar
Pentacyclic Triterpenoids Inhibit IKKβ Mediated Activation of NF-κB Pathway: In Silico and In Vitro Evidences
K. Patil, Purusottam Mohapatra, H. Patel, Sameer N. Goyal +3 more
2015PLoS ONE68 citations Open access
Semantic Scholar
WNT5A as a therapeutic target in breast cancer
C. P. Prasad, M. Manchanda, Purusottam Mohapatra, T. Andersson
2018Cancer Metastasis Review64 citations Open access
Semantic Scholar
Metabolic changes in triple negative breast cancer-focus on aerobic glycolysis
J. R. Dev Arundhathi, S. Mathur, A. Gogia, S. Deo +2 more
2021Molecular Biology Reports59 citations
Semantic Scholar
5-fluorouracil increases the chemopreventive potentials of resveratrol through DNA damage and MAPK signaling pathway in human colorectal cancer cells.
Purusottam Mohapatra, Ranjan Preet, M. Choudhuri, T. Choudhuri +1 more
2011Oncology Research54 citations Open access
Semantic Scholar
Scaffold hybridization in generation of indenoindolones as anticancer agents that induce apoptosis with cell cycle arrest at G2/M phase.
Maneesh Kashyap, D. Das, Ranjan Preet, Purusottam Mohapatra +4 more
2012Bioorganic & Medicinal Chemistry Letters52 citations
Semantic Scholar
Synthesis and biological evaluation of andrographolide analogues as anti-cancer agents.
Ranjan Preet, B. Chakraborty, S. Siddharth, Purusottam Mohapatra +7 more
2014European journal of medicinal chemistry50 citations
Semantic Scholar
5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway
D. Das, Ranjan Preet, Purusottam Mohapatra, S. R. Satapathy +6 more
2014DNA Repair48 citations Open access
Semantic Scholar
Combretastatin A-4 inspired novel 2-aryl-3- arylamino-imidazo-pyridines/pyrazines as tubulin polymerization inhibitors, antimitotic and anticancer agents†
Nitesh Sanghai, V. Jain, Ranjan Preet, Somnath Kandekar +11 more
201446 citations
Semantic Scholar
Resveratrol and curcumin synergistically induces apoptosis in cigarette smoke condensate transformed breast epithelial cells through a p21(Waf1/Cip1) mediated inhibition of Hh-Gli signaling.
Purusottam Mohapatra, S. R. Satapathy, S. Siddharth, D. Das +2 more
2015International Journal of Biochemistry and Cell Biology44 citations
Semantic Scholar
Up-regulation of Nrf2/HO-1 and inhibition of TGF-β1/Smad2/3 signaling axis by daphnetin alleviates transverse aortic constriction-induced cardiac remodeling in mice.
A. Syed, S. Kundu, Chetan Ram, Uttam Kulhari +5 more
2022Free Radical Biology & Medicine42 citations
Semantic Scholar
Resveratrol mediated cell death in cigarette smoke transformed breast epithelial cells is through induction of p21Waf1/Cip1 and inhibition of long patch base excision repair pathway.
Purusottam Mohapatra, S. R. Satapathy, D. Das, S. Siddharth +2 more
2014Toxicology and Applied Pharmacology37 citations
Semantic Scholar
The contribution of heavy metals in cigarette smoke condensate to malignant transformation of breast epithelial cells and in vivo initiation of neoplasia through induction of a PI3K-AKT-NFκB cascade.
Purusottam Mohapatra, Ranjan Preet, D. Das, S. R. Satapathy +4 more
2014Toxicology and Applied Pharmacology35 citations
Semantic Scholar
Indenoindolone derivatives as topoisomerase II-inhibiting anticancer agents.
Maneesh Kashyap, Somnath Kandekar, Ashish T. Baviskar, D. Das +7 more
2013Bioorganic & Medicinal Chemistry Letters35 citations Open access
Semantic Scholar
1,3-Bis(2-chloroethyl)-1-nitrosourea enhances the inhibitory effect of resveratrol on 5-fluorouracil sensitive/resistant colon cancer cells.
D. Das, Ranjan Preet, Purusottam Mohapatra, S. R. Satapathy +1 more
2013World Journal of Gastroenterology33 citations Open access
Semantic Scholar
The Apoptotic Effect of Plant Based Nanosilver in Colon Cancer Cells is a p53 Dependent Process Involving ROS and JNK Cascade
S. R. Satapathy, Purusottam Mohapatra, D. Das, S. Siddharth +1 more
2015Pathology and Oncology Research28 citations
Semantic Scholar
Tribal pest control practices of Tamil Nadu for sustainable agriculture
Purusottam Mohapatra, N. Ponnurasan, .. P.Narayanasamy
200926 citations
Semantic Scholar
WNT5A-Induced Activation of the Protein Kinase C Substrate MARCKS Is Required for Melanoma Cell Invasion
Purusottam Mohapatra, V. Yadav, Maren Toftdahl, T. Andersson
2020Cancers25 citations Open access
Semantic Scholar
Demonstration of a WNT5A-IL-6 positive feedback loop in melanoma cells: Dual interference of this loop more effectively impairs melanoma cell invasion
Rickard Linnskog, Purusottam Mohapatra, Farnaz Moradi, C. P. Prasad +1 more
2016OncoTarget25 citations Open access
Semantic Scholar
Curcumin nanoparticles as a multipurpose additive to achieve high-fidelity SLA-3D printing and controlled delivery.
P. Sharma, Dinesh Choudhury, Tukaram Karanwad, Purusottam Mohapatra +2 more
2023Biomaterials Advances24 citations
Semantic Scholar
Passage number of cancer cell lines: Importance, intricacies, and way‐forward
C. P. Prasad, S. C. Tripathi, Manish Kumar, Purusottam Mohapatra
2023Biotechnology and Bioengineering22 citations
Semantic Scholar
Therapy for BRAFi-Resistant Melanomas: Is WNT5A the Answer?
C. P. Prasad, Purusottam Mohapatra, T. Andersson
2015Cancers22 citations Open access
Semantic Scholar
Optoresponsive Pheophorbide-Silver based organometallic nanomaterials for high efficacy multimodal theranostics in Melanoma
Prathamesh Mahadev Patil, Nidhi Poddar, Nidhi Parihar, Santimoy Sen +3 more
2023Chemical Engineering Journal21 citations
Semantic Scholar
Combination therapy targeting the elevated interleukin‐6 level reduces invasive migration of BRAF inhibitor‐resistant melanoma cells
Purusottam Mohapatra, C. P. Prasad, T. Andersson
2019Molecular Oncology19 citations Open access
Semantic Scholar
Induction of apoptosis by 4-(3-(tert-butylamino)imidazo[1,2-α]pyridine-2-yl) benzoic acid in breast cancer cells via upregulation of PTEN.
S. Siddharth, Purusottam Mohapatra, Ranjan Preet, D. Das +3 more
2013Oncology Research17 citations Open access
Semantic Scholar
Structural Elaboration of a Natural Product: Identification of 3,3′‐Diindolylmethane Aminophosphonate and Urea Derivatives as Potent Anticancer Agents
Somnath Kandekar, Ranjan Preet, Maneesh Kashyap, Renu Prasad M. U. +9 more
2013ChemMedChem14 citations
Semantic Scholar
Abstract A116: Targeting the Wnt-5a signaling pathway as a novel anti-metastatic therapy
T. Andersson, L. Axelsson, Purusottam Mohapatra, C. P. Prasad +7 more
20159 citations
Semantic Scholar
Cytotoxic Effect of Microbial Biosurfactants Against Human Embryonic Kidney Cancerous Cell: HEK-293 and Their Possible Role in Apoptosis
A. Pradhan, N. Pradhan, Purusottam Mohapatra, C. Kundu +2 more
2014Applied Biochemistry and Biotechnology9 citations
Semantic Scholar
Increased MARCKS Activity in BRAF Inhibitor-Resistant Melanoma Cells Is Essential for Their Enhanced Metastatic Behavior Independent of Elevated WNT5A and IL-6 Signaling
Vikas Yadav, Njainday Jobe, S. R. Satapathy, Purusottam Mohapatra +1 more
2022Cancers6 citations Open access
Semantic Scholar
3D printed subcutaneous implant for prolonged delivery of tenofovir with desired release capability, biocompatibility, and viability
M. K. Sharan, Dinesh Choudhury, Purusottam Mohapatra, Subham Banerjee
2024Journal of Molecular Structure5 citations
Semantic Scholar
Nuclear N-WASP Induces Actin Polymerization in the Nucleus with Cortactin as an Essential Factor
Xin Jiang, Purusottam Mohapatra, Maria Rossing, Wenqian Zheng +5 more
2025Cells4 citations Open access
Semantic Scholar
Abstract 2777: Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC
Ranjan Preet, R. Shanmugam, Purusottam Mohapatra, D. Das +3 more
20140 citations
Semantic Scholar
Biological Characteristics of Certain Diamondback Moth Ecotypes
Purusottam Mohapatra, J. Chacko, P.Narayanasamy
20060 citations Open access
Semantic Scholar

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