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Anadina Garcia · SciRah

Researcher profile · Semantic Scholar

Anadina Garcia

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Anadina Garcia — researcher profile on SciRah

h-index: 5
Works: 17
Citations: 173

Most-cited papers

Improved efficacy of a next-generation ERT in murine Pompe disease.
Su Xu, Lun Yi, M. Frascella, Anadina Garcia +15 more
2019JCI Insight79 citations Open access
Semantic Scholar
Coformulation of a Novel Human α-Galactosidase A With the Pharmacological Chaperone AT1001 Leads to Improved Substrate Reduction in Fabry Mice
Su Xu, Lun Yi, N. Brignol, R. Hamler +21 more
2015Molecular Therapy37 citations Open access
Semantic Scholar
The Pharmacological Chaperone AT2220 Increases the Specific Activity and Lysosomal Delivery of Mutant Acid Alpha-Glucosidase, and Promotes Glycogen Reduction in a Transgenic Mouse Model of Pompe Disease
Richie Khanna, A. Powe, Lun Yi, R. Soska +12 more
2014PLoS ONE37 citations Open access
Semantic Scholar
Migalastat Tissue Distribution: Extrapolation From Mice to Humans Using Pharmacokinetic Modeling and Comparison With Agalsidase Beta Tissue Distribution in Mice
Yi-Shuan S. Wu, Richie Khanna, V. Schmith, Lun Yi +10 more
2021Clinical pharmacology in drug development11 citations Open access
Semantic Scholar
Novel recombinant human acid α-glucosidase with optimal glycosylation is significantly better than standard of care enzyme replacement for glycogen clearance in skeletal muscles of GAA knock-out mice
R. Gotschall, Su Xu, Lun Yi, A. Schilling +9 more
20155 citations
Semantic Scholar
Exploring the Use of Pharmacological Chaperone AT3375 Alone and in Combination with Recombinant human ß-Glucosidase for Gaucher Disease
Richie Khanna, Lee J. Pellegrino, R. Soska, Lun Yi +9 more
20123 citations
Semantic Scholar
METABOLIC MYOPATHIES II
Lun Yi, Su Xu, R. Soska, Anju M. Nair +9 more
2018Neuromuscular Disorders1 citations
Semantic Scholar
Histological examination of the effect of a highly phosphorylated proprietary recombinant human acid alpha-glucosidase on glycogen reduction in disease-relevant muscles of Pompe mice
Lun Yi, Su Xu, R. Gotschall, A. Schilling +8 more
20151 citations
Semantic Scholar
Exploring the use of a co-formulated pharmacological chaperone AT2220 with recombinant human acid alpha-glucosidase for Pompe disease
Richie Khanna, Su Xu, Lun Yi, R. Soska +6 more
20131 citations
Semantic Scholar
P.17.8 The co-formulation of pharmacological chaperone AT2220 with recombinant human acid alpha-glucosidase improves enzyme uptake and glycogen reduction in a mouse model of Pompe disease
Richie Khanna, Su Xu, Lee J. Pellegrino, Lun Yi +7 more
20131 citations
Semantic Scholar
A major advance in the search for more effective therapy for Pompe disease
N. Raben, E. Ralston, Lun Yi, A. Ponery +7 more
20180 citations
Semantic Scholar
A novel recombinant human acid alpha-glucosidase, ATB200, leads to greater substrate reduction and improvement in Pompe disease-relevant markers compared to alglucosidase alfa in GAA KO mice
Lun Yi, Su Xu, R. Soska, Anju M. Nair +6 more
20170 citations
Semantic Scholar
P.217 - Stabilized next-generation recombinant human acid alpha-glucosidase ATB200 clears accumulated glycogen and reverses cellular dysfunction to increase muscle strength in a mouse model of Pompe disease
Su Xu, Lun Yi, Anju M. Nair, Michelle Frascella +10 more
20170 citations
Semantic Scholar
Stabilized next-generation recombinant human acid alpha-glucosidase ATB200 clears accumulated glycogen and reverses cellular dysfunction to increase functional muscle strength in a mouse model of Pompe disease
Do Hung, Lun Yi, Su Xu, R. Soska +9 more
20170 citations
Semantic Scholar
Co-administration of the pharmacological chaperone AT2221 with a proprietary recombinant human acid alfa-glucosidase leads to greater plasma exposure and substrate reduction compared to alglucosidase alfa
Richie Khanna, Su Xu, D. Hilliard, Lun Yi +13 more
20160 citations
Semantic Scholar
Subcutaneous administration of recombinant human acid α-glucosidase co-formulated with the pharmacological chaperone AT2220 leads to lysosomal uptake of rhGAA and glycogen reduction in disease-relevant tissues of mice with Pompe disease
Lun Yi, Lee J. Pellegrino, Su Xu, Jessie Feng +7 more
20140 citations
Semantic Scholar
O1‐11‐05: Pharmacological chaperones increase wild type presenilin 1 levels and promote the normalization of gamma‐secretase function in presenilin 1 early‐onset familial Alzheimer's disease models
A. Stevens, Hadis Williams, Carol J. Collins, Mohammed Mughal +15 more
20120 citations Open access
Semantic Scholar

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