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David A. Crispin · SciRah

Researcher profile · Semantic Scholar

David A. Crispin

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David A. Crispin — researcher profile on SciRah

h-index: 27
Works: 49
Citations: 4,071

Most-cited papers

Mutations in the p53 gene: an early marker of neoplastic progression in ulcerative colitis.
T. Brentnall, David A. Crispin, P. Rabinovitch, R. Haggitt +3 more
1994Gastroenterology452 citations
Semantic Scholar
Chromosomal instability in ulcerative colitis is related to telomere shortening
J. O'Sullivan, M. Bronner, T. Brentnall, Jennifer C. Finley +8 more
2002Nature Genetics352 citations
Semantic Scholar
Risk and natural history of colonic neoplasia in patients with primary sclerosing cholangitis and ulcerative colitis.
T. Brentnall, R. Haggitt, P. Rabinovitch, M. Kimmey +7 more
1996Gastroenterology330 citations
Semantic Scholar
Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart
Dao-Fu Dai, P. Karunadharma, Y. Chiao, N. Basisty +9 more
2014Aging Cell317 citations Open access
Semantic Scholar
Microsatellite instability in nonneoplastic mucosa from patients with chronic ulcerative colitis.
T. Brentnall, David A. Crispin, M. Bronner, Sajeev P. Cherian +5 more
1996Cancer Research291 citations
Semantic Scholar
Neoplastic progression in ulcerative colitis: histology, DNA content, and loss of a p53 allele.
G. C. Burmer, P. Rabinovitch, R. Haggitt, David A. Crispin +4 more
1992Gastroenterology289 citations
Semantic Scholar
Palladin Mutation Causes Familial Pancreatic Cancer and Suggests a New Cancer Mechanism
K. Pogue-Geile, Ru Chen, M. Bronner, T. Crnogorac-Jurcevic +7 more
2006PLoS Medicine229 citations Open access
Semantic Scholar
Pancreatic cancer proteome: the proteins that underlie invasion, metastasis, and immunologic escape.
Ru Chen, E. Yi, S. Donohoe, Sheng Pan +8 more
2005Gastroenterology190 citations
Semantic Scholar
Pancolonic chromosomal instability precedes dysplasia and cancer in ulcerative colitis.
P. Rabinovitch, Shawna M. Dziadon, T. Brentnall, M. Emond +3 more
1999Cancer Research187 citations
Semantic Scholar
Evolution of the salmonid mitochondrial control region.
A. Shedlock, Jay D. Parker, David A. Crispin, Theodore W. Pietsch +1 more
1992Molecular Phylogenetics and Evolution142 citations
Semantic Scholar
A new susceptibility locus for autosomal dominant pancreatic cancer maps to chromosome 4q32-34.
M. Eberle, R. Pfützer, K. Pogue-Geile, M. Bronner +6 more
2002American Journal of Human Genetics129 citations Open access
Semantic Scholar
Protein alterations associated with pancreatic cancer and chronic pancreatitis found in human plasma using global quantitative proteomics profiling
Sheng Pan, Ru Chen, David A. Crispin, Damon H. May +6 more
2011Journal of Proteome Research112 citations Open access
Semantic Scholar
Tumor-infiltrating Merkel cell polyomavirus-specific T cells are diverse and associated with improved patient survival
Natalie J. Miller, C. Church, Lichun Dong, David A. Crispin +10 more
2017Cancer immunology research86 citations Open access
Semantic Scholar
Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects
P. Karunadharma, N. Basisty, Dao-Fu Dai, Y. Chiao +9 more
2015Aging Cell83 citations Open access
Semantic Scholar
Quantitative Proteomics Analysis Reveals That Proteins Differentially Expressed in Chronic Pancreatitis Are Also Frequently Involved in Pancreatic Cancer*S
Ru Chen, T. Brentnall, Sheng Pan, Kelly Cooke +6 more
2007Molecular & Cellular Proteomics83 citations Open access
Semantic Scholar
Quantitative Glycoproteomics Analysis Reveals Changes in N-Glycosylation Level Associated with Pancreatic Ductal Adenocarcinoma
Sheng Pan, Ru Chen, Yasuko Tamura, David A. Crispin +5 more
2014Journal of Proteome Research81 citations Open access
Semantic Scholar
DNA fingerprinting abnormalities can distinguish ulcerative colitis patients with dysplasia and cancer from those who are dysplasia/cancer-free.
Ru Chen, P. Rabinovitch, David A. Crispin, M. Emond +3 more
2003American Journal of Pathology74 citations Open access
Semantic Scholar
The initiation of colon cancer in a chronic inflammatory setting.
Ru Chen, P. Rabinovitch, David A. Crispin, M. Emond +2 more
2005Carcinogenesis73 citations Open access
Semantic Scholar
Familial Fibrocystic Pancreatic Atrophy With Endocrine Cell Hyperplasia and Pancreatic Carcinoma
Kenneth A. Meckler, T. Brentnall, R. Haggitt, David A. Crispin +3 more
2001American Journal of Surgical Pathology69 citations
Semantic Scholar
Clonal expansions in ulcerative colitis identify patients with neoplasia
J. Salk, S. Salipante, R. Risques, David A. Crispin +6 more
2009Proceedings of the National Academy of Sciences of the United States of America66 citations Open access
Semantic Scholar
Frequent loss of a p53 allele in carcinomas and their precursors in ulcerative colitis.
G. C. Burmer, David A. Crispin, V. R. Kolli, R. Haggitt +3 more
1991Cancer Communications63 citations Open access
Semantic Scholar
Quantitative proteomics investigation of pancreatic intraepithelial neoplasia
Sheng Pan, Ru Chen, Beth Ann Reimel, David A. Crispin +10 more
2009Electrophoresis59 citations Open access
Semantic Scholar
Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma
Ru Chen, David W. Dawson, Sheng Pan, N. A. Ottenhof +12 more
2014Laboratory Investigation51 citations Open access
Semantic Scholar
Proteins That Underlie Neoplastic Progression of Ulcerative Colitis
Teresa Brentnall, Sheng Pan, M. Bronner, David A. Crispin +10 more
2009PROTEOMICS - Clinical Applications49 citations Open access
Semantic Scholar
Investigating neoplastic progression of ulcerative colitis with label-free comparative proteomics
Damon H. May, Sheng Pan, David A. Crispin, K. Lai +6 more
2010Journal of Proteome Research48 citations Open access
Semantic Scholar
Pilot study of blood biomarker candidates for detection of pancreatic cancer Short running title: Pilot study of pancreatic cancer blood biomarkers
Ru Chen, David A. Crispin, Sheng Pan, S. Hawley +6 more
2010Pancreas28 citations Open access
Semantic Scholar
Up-regulation of mitochondrial chaperone TRAP1 in ulcerative colitis associated colorectal cancer.
Ru Chen, Sheng Pan, K. Lai, L. Lai +3 more
2014World Journal of Gastroenterology27 citations Open access
Semantic Scholar
Clonal expansions and short telomeres are associated with neoplasia in early-onset, but not late-onset, ulcerative colitis
J. Salk, A. Bansal, L. Lai, David A. Crispin +7 more
2013Inflammatory Bowel Diseases27 citations Open access
Semantic Scholar
Characterization of genomic instability in ulcerative colitis neoplasia leads to discovery of putative tumor suppressor regions.
Ru Chen, M. Bronner, David A. Crispin, P. Rabinovitch +1 more
2005Cancer Genetics and Cytogenetics19 citations
Semantic Scholar
Global Proteomics and Pathway Analysis of Pressure-overload Induced Heart Failure and Its Attenuation by Mitochondrial Targeted Peptides
Dao-Fu Dai, Edward J. Hsieh, Tony Chen, L. G. Menendez +9 more
2013Circulation: Heart Failure18 citations Open access
Semantic Scholar
Pan-colonic field defects are detected by CGH in the colons of UC patients with dysplasia/cancer
L. Lai, R. Risques, M. Bronner, P. Rabinovitch +3 more
2012Cancer Letters15 citations Open access
Semantic Scholar
Array Comparative Genomic Hybridization in Ulcerative Colitis Neoplasia: Single Non-Dysplastic Biopsies Distinguish Progressors from Non-Progressors
M. Bronner, M. Skacel, David A. Crispin, Peter D. Hoff +6 more
2010Modern Pathology11 citations Open access
Semantic Scholar
Risk and natural history of colonic neoplastic progression in patients with primary sclerosing cholangitis and ulcerative colitis
T. Brentnall, R. Haggitt, P. Rabinovitch, M. Kimmey +4 more
19959 citations Open access
Semantic Scholar
Gene Expression and Proteomic Analysis of Pancreatic Cancer: a Recent Update.
Ru Chen, Sheng Pan, David A. Crispin, T. Brentnall
2006Cancer Genomics & Proteomics8 citations
Semantic Scholar
A germline substitution in the MSH2 gene is associated with neoplasia in ulcerative colitis
T. Brentnall, C. E. Rubin, David A. Crispin, A. Stevens +7 more
19953 citations Open access
Semantic Scholar
Identifying abundant immunotherapy and other targets in solid tumors: integrating RNA-seq and Mass Spectrometry proteomics data sets
Wei Zhao, Matthew P. Fitzgibbon, Lindsay A. Bergan, Nigel Clegg +3 more
2017Cancer Journal2 citations Open access
Semantic Scholar
Abstract 5742: Up-regulation of mitochondrial chaperone TRAP1 in cancer precursors associated with chronic inflammation
Ru Chen, Sheng Pan, M. Bronner, K. Lai +3 more
20120 citations
Semantic Scholar
Alpha Zinc Glycoprotein 1 (AZGP1) Blood Test for Chronic Pancreatitis (CP)
T. Stevens, Sheng Pan, Ru Chen, David A. Crispin +4 more
20110 citations
Semantic Scholar
Abstract 5072: Protein signatures associated with dysplasia of ulcerative colitis
Sheng Pan, David A. Crispin, Damon H. May, M. Bronner +5 more
20110 citations
Semantic Scholar
Abstract 5106: Development of plasma biomarkers for pancreatic cancer diagnosis
Sheng Pan, Ru Chen, David A. Crispin, Damon H. May +6 more
20110 citations
Semantic Scholar
Abstract 4707: Clonal expansions as a biomarker of preneoplastic processes in ulcerative colitis
J. Salk, S. Salipante, R. Risques, David A. Crispin +6 more
20100 citations
Semantic Scholar
S1932 Identification of Potential Novel Risk Stratification Markers for Ulcerative Colitis-Associated Dysplasia Using Methylation Arrays
A. Kaz, M. Bronner, Ru Chen, David A. Crispin +2 more
20100 citations Open access
Semantic Scholar
Abstract 4562: Alteration of mitochondrial proteome in neoplastic progression of ulcerative colitis
Sheng Pan, T. Brentnall, David A. Crispin, M. Bronner +5 more
20100 citations
Semantic Scholar
O-0020: Quantitative proteomics profiling of neoplastic progression of ulcerative colitis
Sheng Pan, David A. Crispin, H. Mirzaei, Y. Tamura +7 more
20080 citations
Semantic Scholar
Quantitative proteomics profiling of neoplastic progression of ulcerative colitis: O-0020.
Sheng Pan, David A. Crispin, H. Mirzaei, Y. Tamura +8 more
20080 citations
Semantic Scholar
Chromosomal instability is associated with telomere shortening in UC patients with dysplasia or cancer
David A. Crispin, Shawna M. Dziadon, R. Haggitt, P. Rabinovitch +1 more
20000 citations
Semantic Scholar
Chromosomal instability is present throughout the colon of UC patients who have dysplasia but not in UC patients who are non-dysplastic
Shawna M. Dziadon, David A. Crispin, M. Emond, R. Haggitt +2 more
20000 citations Open access
Semantic Scholar
Genetic instability in grossly normal pancreatic duct cells from patients with chronic pancreatitis and pancreatic cancer
A. M. Brown, M. Bronner, T. Brentnall, P. Rabinovitch +8 more
20000 citations
Semantic Scholar
Chromosomal instability in early ulcerative colitis tumorigenesis
M. Bronner, S. Ranz, P. Rabinovitch, David A. Crispin +2 more
19980 citations Open access
Semantic Scholar

Frequent co-authors

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T. Brentnall×38
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T. Brentnall — researcher profile on SciRah
M. Bronner×37
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M. Bronner — researcher profile on SciRah
P. Rabinovitch×25
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P. Rabinovitch — researcher profile on SciRah
Ru Chen×24
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Ru Chen — researcher profile on SciRah

×17

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Sheng Pan — researcher profile on SciRah

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R. Haggitt — researcher profile on SciRah

M. Mcintosh×12

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M. Mcintosh — researcher profile on SciRah

Damon H. May×9

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Damon H. May — researcher profile on SciRah

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L. Lai — researcher profile on SciRah

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M. Emond — researcher profile on SciRah

R. Aebersold×6

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R. Aebersold — researcher profile on SciRah

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C. E. Rubin — researcher profile on SciRah