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R. de Knegt · SciRah

Researcher profile · Semantic Scholar

R. de Knegt

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R. de Knegt — researcher profile on SciRah

h-index: 56
Works: 357
Citations: 13K

Most-cited papers

Global prevalence, cascade of care, and prophylaxis coverage of hepatitis B in 2022: a modelling study.
D. Razavi-Shearer, I. Gamkrelidze, C. Pan, Jidong Jia +267 more
2023The Lancet Gastroenterology and Hepatology360 citations Open access
Semantic Scholar
An international multidisciplinary consensus statement on MAFLD and the risk of CVD
Xiao-Dong Zhou, G. Targher, C. Byrne, V. Somers +44 more
2023Hepatology International174 citations Open access
Semantic Scholar
Development, validation, and prognostic evaluation of a risk score for long-term liver-related outcomes in the general population: a multicohort study.
M. Serra-Burriel, A. Juanola, Feliu Serra-Burriel, M. Thiele +55 more
2023The Lancet127 citations Open access
Semantic Scholar
The role of dietary modification in the prevention and management of metabolic dysfunction-associated fatty liver disease: an international multidisciplinary expert consensus.
Xu-Fen Zeng, K. Varady, Xiang-Dong Wang, G. Targher +51 more
2024Metabolism: Clinical and Experimental126 citations Open access
Semantic Scholar
Dissecting the multifaceted impact of statin use on fatty liver disease: A multidimensional study
I. Ayada, L. V. van Kleef, Huai Zhang, Kuan Liu +10 more
2022EBioMedicine111 citations Open access
Semantic Scholar
MAF-5 PREDICTS LIVER FIBROSIS RISK AND OUTCOME IN THE GENERAL POPULATION WITH METABOLIC DYSFUNCTION.
L. V. van Kleef, S. Francque, J. Prieto-Ortiz, M. Sonneveld +10 more
2024Gastroenterology65 citations Open access
Semantic Scholar
LIVER STIFFNESS, BUT NOT FATTY LIVER DISEASE, IS ASSOCIATED WITH ATRIAL FIBRILLATION: THE ROTTERDAM STUDY.
L. V. van Kleef, Zuo-Lin Lu, M. Ikram, N. D. de Groot +2 more
2022Journal of Hepatology56 citations Open access
Semantic Scholar
Metabolic dysfunction‐associated fatty liver disease and excessive alcohol consumption are both independent risk factors for mortality
L. V. van Kleef, R. de Knegt, W. Brouwer
2022Hepatology50 citations Open access
Semantic Scholar
Single-cell RNA sequencing of liver fine-needle aspirates captures immune diversity in the blood and liver in chronic hepatitis B patients
Alex S. Genshaft, S. Subudhi, A. Keo, J. D. Sanchez Vasquez +31 more
2023Hepatology44 citations Open access
Semantic Scholar
Nonalcoholic fatty liver disease, liver fibrosis, and structural brain imaging: The Cross‐Cohort Collaboration
G. Weinstein, A. O’Donnell, S. Frenzel, Tian Xiao +15 more
2023European Journal of Neurology33 citations Open access
Semantic Scholar
Differential prevalence and prognostic value of metabolic syndrome components among patients with MASLD
Jesse Pustjens, L. V. van Kleef, H. L. A. Janssen, R. de Knegt +1 more
2024JHEP Reports29 citations Open access
Semantic Scholar
LiverScreen project: study protocol for screening for liver fibrosis in the general population in European countries
I. Graupera, Maja Thiele, A. Ma, M. Serra-Burriel +42 more
2022BMC Public Health29 citations Open access
Semantic Scholar
Plasma proteomic signature of fatty liver disease: The Rotterdam Study
Yasir J. Abozaid, I. Ayada, L. V. van Kleef, C. Vallerga +6 more
2023Hepatology25 citations Open access
Semantic Scholar
Association of Nonalcoholic Fatty Liver Disease and Fibrosis With Incident Dementia and Cognition
Tian Xiao, L. V. van Kleef, M. Ikram, R. de Knegt +1 more
2022Neurology25 citations Open access
Semantic Scholar
Fatty liver disease is not associated with increased mortality in the elderly: A prospective cohort study
L. V. van Kleef, M. Sonneveld, M. Kavousi, M. Ikram +2 more
2022Hepatology25 citations Open access
Semantic Scholar
Prevalence of liver fibrosis in the general population (the LiverScreen project): a multinational European cohort study.
I. Graupera, Maja Thiele, L. Castera, Guillem Pera +78 more
2026The Lancet24 citations Open access
Semantic Scholar
Screening for fibrosis to diagnose liver diseases early: the LIVERSCREEN project
P. Ginés, M. Thiele, I. Graupera, M. Serra-Burriel +10 more
2023Nature Medicine24 citations Open access
Semantic Scholar
Associations of Sex Steroids and Sex Hormone-Binding Globulin with Non-Alcoholic Fatty Liver Disease: A Population-Based Study and Meta-Analysis
Xiao-Fang Zhang, Yu-Chan Mou, E. Aribas, M. Amiri +6 more
2022Genes23 citations Open access
Semantic Scholar
Hepatitis C Elimination in the Netherlands (CELINE): How nationwide retrieval of lost to follow-up hepatitis C patients contributes to micro-elimination.
C. Isfordink, M. van Dijk, S. Brakenhoff, P. Kracht +4 more
2022European journal of internal medicine21 citations Open access
Semantic Scholar
Levels of Antibodies to Hepatitis B Core Antigen Are Associated With Liver Inflammation and Response to Peginterferon in Patients With Chronic Hepatitis B
S. Brakenhoff, R. de Knegt, Jeffrey Oliveira, A. A. van der Eijk +6 more
2022Journal of Infectious Diseases20 citations Open access
Semantic Scholar
The Steatosis-associated fibrosis estimator (SAFE) score: validation in the general US population
L. V. van Kleef, R. de Knegt, I. Ayada, Q. Pan +1 more
2023Hepatology Communications19 citations Open access
Semantic Scholar
Addition of PEG‐interferon to long‐term nucleos(t)ide analogue therapy enhances HBsAg decline and clearance in HBeAg‐negative chronic hepatitis B
M. S. Farag, M. V. van Campenhout, M. Sonneveld, Scott Fung +12 more
2024Journal of Viral Hepatitis18 citations Open access
Semantic Scholar
End-of-treatment HBsAg, HBcrAg and HBV RNA predict the risk of off-treatment ALT flares in chronic hepatitis B patients.
S. Brakenhoff, R. de Knegt, M. V. van Campenhout, A. A. van der Eijk +8 more
2022Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi18 citations Open access
Semantic Scholar
Evaluation of nonalcoholic fatty liver disease (NAFLD) in severe obesity using noninvasive tests and imaging techniques
W. Theel, B. B. Boxma-de Klerk, F. Dirksmeier-Harinck, E. V. van Rossum +9 more
2022Obesity Reviews18 citations Open access
Semantic Scholar
Hepatocellular carcinoma risk in Sub-Saharan African and Afro-Surinamese individuals with chronic hepatitis B living in Europe.
L. Patmore, Kirsi M. A. van Eekhout, M. Buti, Ö. Koc +14 more
2023Journal of Hepatology16 citations Open access
Semantic Scholar
Liver stiffness is associated with excess mortality in the general population driven by heart failure: The Rotterdam Study
L. V. van Kleef, M. Sonneveld, F. Zhu, M. Ikram +2 more
2023Liver international (Print)16 citations Open access
Semantic Scholar
Author Response: Association of Nonalcoholic Fatty Liver Disease and Fibrosis With Incident Dementia and Cognition: The Rotterdam Study
L. V. van Kleef, Tian Xiao, R. de Knegt, M. Ikram
2023Neurology15 citations
Semantic Scholar
The global prevalence and impact of steatotic liver disease and viral infections: A systematic review and meta-analysis
Jia-Jing Li, Jiahua Zhou, Peng-Fei Li, Yi-Ning Wang +14 more
2025Hepatology Communications14 citations Open access
Semantic Scholar
Association of HBsAg levels with differential gene expression in NK, CD8 T, and memory B cells in treated patients with chronic HBV
Boris J. B. Beudeker, Z. Osmani, G. V. van Oord, Z. Groothuismink +5 more
2023JHEP Reports14 citations Open access
Semantic Scholar
Spleen Stiffness Measurement Across the Spectrum of Liver Disease Patients in Real-World Practice
M. Lantinga, L. V. van Kleef, C. D. den Hoed, R. de Knegt
2022Journal of Clinical and Experimental Hepatology13 citations Open access
Semantic Scholar
The Association Between Metabolic Dysfunction‐Associated Steatotic Liver Disease and Change in Liver Stiffness in Patients With Chronic Hepatitis B
L. Patmore, Kirsi M. A. van Eekhout, Ö. Koc, R. de Knegt +11 more
2025Liver international (Print)12 citations Open access
Semantic Scholar
The new international nomenclature for steatotic liver disease: One step forward towards enhanced awareness for healthier life.
K. V. van Erpecum, L. V. van Kleef, U. Beuers, R. de Knegt
2023European journal of internal medicine11 citations Open access
Semantic Scholar
Fatty Liver Index and mortality after myocardial infarction: A prospective analysis in the Alpha Omega Cohort
Luc Heerkens, L. V. van Kleef, R. de Knegt, T. Voortman +1 more
2023PLoS ONE11 citations Open access
Semantic Scholar
Epidemiology and management of hepatitis B and C in primary care in the Netherlands: data from the Rijnmond Primary Care database
S. Brakenhoff, Robert A. de Man, R. de Knegt, P. Bindels +1 more
2022Family Practice11 citations Open access
Semantic Scholar
Imaging-based body fat depots and new-onset atrial fibrillation in general population: a prospective cohort study
Zuo-Lin Lu, M. Tilly, E. Aribas, D. Bos +7 more
2022BMC Medicine10 citations Open access
Semantic Scholar
Diabetes Mellitus is a Risk Factor for Hepatic Encephalopathy Following Transjugular Intrahepatic Portosystemic Shunt
M. Spaan, Ellen Werner, W. Dijkstra, N. Erler +13 more
2025Alimentary Pharmacology and Therapeutics9 citations Open access
Semantic Scholar
Comparison of diagnostic accuracy and utility of non-invasive tests for clinically significant liver disease in a general population with metabolic dysfunction.
L. V. van Kleef, Jesse Pustjens, J. Schattenberg, A. G. Holleboom +7 more
2025Hepatology9 citations Open access
Semantic Scholar
Plasma MicroRNA Signature of Alcohol Consumption: The Rotterdam Study
Irma Karabegović, Yasir J. Abozaid, Silvana C. E. Maas, J. Labrecque +5 more
2022Journal of NutriLife9 citations Open access
Semantic Scholar
Effect of bariatric surgery on NAFLD/NASH: a single-centre observational prospective cohort study
W. Theel, B. B. Boxma-de Klerk, F. Dirksmeier-Harinck, E. V. van Rossum +10 more
2023BMJ Open7 citations Open access
Semantic Scholar
Patients treated with rituximab are poorly screened for hepatitis B infection: Data from a low-incidence country.
S. Brakenhoff, R. Hoekstra, P. Honkoop, R. Roomer +5 more
2022European journal of internal medicine7 citations Open access
Semantic Scholar
Liver stiffness dynamics in European populations (LiverScreen): a longitudinal, multicentre, prospective, population-based cohort study.
Jesse Pustjens, K. Bech, Guillem Pera, L. V. van Kleef +18 more
2026The Lancet Gastroenterology and Hepatology6 citations
Semantic Scholar
Impact of chronic hepatitis B and concurrent steatosis on the risk of hepatocellular carcinoma
I. Ayada, Jia-Jing Li, W. Brouwer, R. de Knegt +1 more
2024Hepatology International6 citations Open access
Semantic Scholar
B-Cell Activation Gene Signature in Blood and Liver of Hepatitis B e Antigen–Positive Patients With Immune Active Chronic Hepatitis B
Z. Osmani, Boris J. B. Beudeker, Z. Groothuismink, R. de Knegt +9 more
2024Journal of Infectious Diseases6 citations Open access
Semantic Scholar
Sustained response and HBsAg loss after nucleo(s)tide analogue discontinuation in chronic hepatitis B patients: the prospective SNAP study.
S. Brakenhoff, M. Claassen, P. Honkoop, R. de Knegt +4 more
2023Clinics And Research in Hepatology and Gastroenterology6 citations Open access
Semantic Scholar
The Yield of Routine Post-Operative Doppler Ultrasound to Detect Early Post-Liver Transplantation Vascular Complications
Iulia Minciuna, C. D. den Hoed, A. V. D. van der Meer, M. Sonneveld +6 more
2023Transplant International6 citations Open access
Semantic Scholar
Sex-stratified associations between fatty liver disease and Parkinson's disease: The Rotterdam study.
L. V. van Kleef, Tian Xiao, M. Ikram, M. Ikram +1 more
2022Parkinsonism & Related Disorders6 citations Open access
Semantic Scholar
Integrating Gut Microbiome and Metabolome to Gain Insight into Metabolic Dysfunction-Associated Steatotic Liver Disease
Xiao-Fang Zhang, Jin-Luan Chen, L. V. van Kleef, C. Medina-Gomez +7 more
2025Gastro Hep Advances5 citations Open access
Semantic Scholar
Intrahepatic plasma cells, but not atypical memory B cells, associate with clinical phases of chronic hepatitis B
Z. Osmani, Martin A. Villanueva, Jasmin Joseph-Chazan, Boris J. B. Beudeker +11 more
2024European Journal of Immunology5 citations Open access
Semantic Scholar
Current Tolerance-Associated Peripheral Blood Gene Expression Profiles After Liver Transplantation Are Influenced by Immunosuppressive Drugs and Prior Cytomegalovirus Infection
Aafke A. Duizendstra, Michelle V. van der Grift, P. Boor, Lisanne Noordam +5 more
2022Frontiers in Immunology5 citations Open access
Semantic Scholar
Tamoxifen use and potential effects on liver parenchyma: A long‐term prospective transient elastographic evaluation
C. Louwrens Braal, R. de Knegt, A. Jager, S. Koolen +2 more
2022Hepatology Communications5 citations Open access
Semantic Scholar

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L. V. van Kleef×21
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L. V. van Kleef — researcher profile on SciRah
M. Sonneveld×13
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W. Brouwer×11
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Robert A. de Man×9
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M. Serra-Burriel — researcher profile on SciRah