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A. Kichler · SciRah

Researcher profile · Semantic Scholar

A. Kichler

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A. Kichler — researcher profile on SciRah

h-index: 35
Works: 112
Citations: 4,982

Most-cited papers

Polyethylenimine‐mediated gene delivery: a mechanistic study
A. Kichler, C. Leborgne, Emmanuel Coeytaux, O. Danos
2001Journal of Gene Medicine514 citations
Semantic Scholar
Gene transfer with modified polyethylenimines
A. Kichler
2004Journal of Gene Medicine251 citations
Semantic Scholar
Histidine-rich amphipathic peptide antibiotics promote efficient delivery of DNA into mammalian cells
A. Kichler, C. Leborgne, Josefine März, O. Danos +1 more
2003Proceedings of the National Academy of Sciences of the United States of America225 citations Open access
Semantic Scholar
Synthesis of linear polyethylenimine derivatives for DNA transfection.
Blandine Brissault, A. Kichler, C. Guis, C. Leborgne +2 more
2003Bioconjugate chemistry202 citations
Semantic Scholar
Efficient in vitro and in vivo pulmonary delivery of nucleic acid by carbon dot-based nanocarriers.
P. Pierrat, Rongrong Wang, D. Kereselidze, Marie Lux +4 more
2015Biomaterials152 citations Open access
Semantic Scholar
Recent developments in nucleic acid delivery with polyethylenimines.
P. Neuberg, A. Kichler
2014Advances in Genetics151 citations
Semantic Scholar
Intranasal gene delivery with a polyethylenimine-PEG conjugate.
A. Kichler, M. Chillón, C. Leborgne, O. Danos +1 more
2002Journal of Controlled Release126 citations
Semantic Scholar
Cationic amphipathic histidine-rich peptides for gene delivery.
A. Kichler, A. J. Mason, B. Bechinger
2006Biochimica et Biophysica Acta121 citations Open access
Semantic Scholar
AON-mediated Exon Skipping Restores Ciliation in Fibroblasts Harboring the Common Leber Congenital Amaurosis CEP290 Mutation
X. Gérard, I. Perrault, S. Hanein, Eduardo Silva +8 more
2012Molecular Therapy: Nucleic Acids106 citations Open access
Semantic Scholar
Design and Evaluation of Histidine-Rich Amphipathic Peptides for siRNA Delivery
Bérangère Langlet-Bertin, C. Leborgne, D. Scherman, B. Bechinger +2 more
2010Pharmaceutical Research89 citations
Semantic Scholar
Structural Determinants of Antimicrobial and Antiplasmodial Activity and Selectivity in Histidine-rich Amphipathic Cationic Peptides*
A. J. Mason, W. Moussaoui, Tamer Abdelrahman, Alyae Boukhari +12 more
2009Journal of Biological Chemistry89 citations Open access
Semantic Scholar
Enhanced Membrane Disruption and Antibiotic Action against Pathogenic Bacteria by Designed Histidine-Rich Peptides at Acidic pH
A. J. Mason, C. Gasnier, A. Kichler, G. Prévost +3 more
2006Antimicrobial Agents and Chemotherapy83 citations Open access
Semantic Scholar
An imidazole modified lipid confers enhanced mRNA-LNP stability and strong immunization properties in mice and non-human primates
M. Ripoll, Marie-Clotilde Bernard, Céline Vaure, Emilie Bazin +8 more
2022Biomaterials72 citations Open access
Semantic Scholar
Efficient DNA Transfection Mediated by the C-Terminal Domain of Human Immunodeficiency Virus Type 1 Viral Protein R
A. Kichler, Jean-Christophe Pagès, C. Leborgne, S. Druillennec +6 more
2000Journal of Virology70 citations Open access
Semantic Scholar
Self‐aggregating 1.8 kDa polyethylenimines with dissolution switch at endosomal acidic pH are delivery carriers for plasmid DNA, mRNA, siRNA and exon‐skipping oligonucleotides
M. Chiper, N. Tounsi, R. Kole, A. Kichler +1 more
2017Journal of Controlled Release69 citations Open access
Semantic Scholar
Vectofusin-1, a New Viral Entry Enhancer, Strongly Promotes Lentiviral Transduction of Human Hematopoietic Stem Cells
D. Fenard, Dina Ingrao, A. Seye, J. Buisset +4 more
2013Molecular Therapy: Nucleic Acids69 citations Open access
Semantic Scholar
A cell-penetrating foldamer with a bioreducible linkage for intracellular delivery of DNA.
C. Douat, C. Aisenbrey, S. Antunes, M. Decossas +4 more
2015Angewandte Chemie67 citations
Semantic Scholar
The Cationic Amphipathic α-Helix of HIV-1 Viral Protein R (Vpr) Binds to Nucleic Acids, Permeabilizes Membranes, and Efficiently Transfects Cells*
Emmanuel Coeytaux, D. Coulaud, É. Le Cam, O. Danos +1 more
2003Journal of Biological Chemistry63 citations Open access
Semantic Scholar
Optimising histidine rich peptides for efficient DNA delivery in the presence of serum.
A. J. Mason, C. Leborgne, Gilles Moulay, Amélie Martinez +3 more
2007Journal of Controlled Release62 citations
Semantic Scholar
Characterization of the gene transfer process mediated by histidine-rich peptides
A. Kichler, C. Leborgne, O. Danos, B. Bechinger
2007Journal of molecular medicine60 citations
Semantic Scholar
Efficient DNA Transfection Mediated by the C-Terminal Domain of Human Immunodeficiency Virus Type 1 Viral Protein R
A. Kichler, J. Pagès, C. Leborgne, S. Druillennec +6 more
2000Journal of Virology60 citations Open access
Semantic Scholar
Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation
J. Barallobre-Barreiro, S. Gupta, A. Zoccarato, Rika Kitazume-Taneike +22 more
2016Circulation52 citations Open access
Semantic Scholar
Histidine‐rich designer peptides of the LAH4 family promote cell delivery of a multitude of cargo
Gilles Moulay, C. Leborgne, A. J. Mason, C. Aisenbrey +2 more
2017Journal of Peptide Science51 citations Open access
Semantic Scholar
Self-promoted cellular uptake of peptide/DNA transfection complexes.
Lydia Prongidi-Fix, Masae Sugawara, P. Bertani, J. Raya +3 more
2007Biochemistry47 citations
Semantic Scholar
Inhibition of the myostatin/Smad signaling pathway by short decorin-derived peptides.
Nelly El Shafey, Mickaël Guesnon, F. Simon, E. Deprez +5 more
2016Experimental Cell Research44 citations
Semantic Scholar
Membrane interaction of chrysophsin-1, a histidine-rich antimicrobial peptide from red sea bream.
A. J. Mason, P. Bertani, Gilles Moulay, Arnaud Marquette +4 more
2007Biochemistry42 citations
Semantic Scholar
Incorporation of 2,3-diaminopropionic acid in linear cationic amphipathic peptides produces pH sensitive vectors
Y. Lan, Bérangère Langlet-Bertin, V. Abbate, Louic S. Vermeer +9 more
2010ChemBioChem41 citations Open access
Semantic Scholar
Dilution of reporter gene with stuffer DNA does not alter the transfection efficiency of polyethylenimines
A. Kichler, C. Leborgne, O. Danos
2005Journal of Gene Medicine39 citations
Semantic Scholar
"HFP" fluorinated cationic lipids for enhanced lipoplex stability and gene delivery.
E. Klein, M. Ciobanu, Jerome Klein, Valérie Machi +7 more
2010Bioconjugate chemistry35 citations
Semantic Scholar
Development and characterization of new cyclodextrin polymer-based DNA delivery systems.
V. Burckbuchler, V. Wintgens, C. Leborgne, S. Lecomte +4 more
2008Bioconjugate chemistry34 citations
Semantic Scholar
pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery.
M. Ripoll, P. Neuberg, A. Kichler, N. Tounsi +2 more
2016ACS Applied Materials and Interfaces32 citations Open access
Semantic Scholar
Cationic steroid antibiotics demonstrate DNA delivery properties.
A. Kichler, C. Leborgne, P. Savage, O. Danos
2005Journal of Controlled Release31 citations
Semantic Scholar
Molecular Determinants of Vectofusin-1 and Its Derivatives for the Enhancement of Lentivirally Mediated Gene Transfer into Hematopoietic Stem/Progenitor Cells*
S. Majdoul, A. Seye, A. Kichler, N. Holic +3 more
2015Journal of Biological Chemistry29 citations Open access
Semantic Scholar
DNA compaction into new DNA vectors based on cyclodextrin polymer: Surface enhanced Raman spectroscopy characterization
V. Burckbuchler, V. Wintgens, S. Lecomte, A. Percot +4 more
2006Biopolymers27 citations
Semantic Scholar
Polyethylenimines: A Family of Potent Polymers for Nucleic Acid Delivery
A. Kichler, J. Behr, P. Erbacher
199927 citations
Semantic Scholar
Control of pH responsive peptide self-association during endocytosis is required for effective gene transfer
Valentina Iacobucci, F. Di Giuseppe, Bui T. T. Tam, Louic S. Vermeer +5 more
2011Biochimica et Biophysica Acta26 citations Open access
Semantic Scholar
Nucleic acid transfer with hemifluorinated polycationic lipids.
E. Klein, C. Leborgne, M. Ciobanu, Jerome Klein +6 more
2010Biomaterials26 citations
Semantic Scholar
Synthesis and Evaluation of Amphiphilic Poly(tetrahydrofuran-b-ethylene oxide) Copolymers for DNA Delivery into Skeletal Muscle
C. Pomel, C. Leborgne, H. Chéradame, D. Scherman +2 more
2008Pharmaceutical Research25 citations
Semantic Scholar
Membrane pore-formation correlates with the hydrophilic angle of histidine-rich amphipathic peptides with multiple biological activities.
Morane Lointier, C. Aisenbrey, Arnaud Marquette, Jia-Hao Tan +2 more
2020Biochimica et Biophysica Acta - Biomembranes24 citations Open access
Semantic Scholar
Quantitative measurement of delivery and gene silencing activities of siRNA polyplexes containing pyridylthiourea-grafted polyethylenimines.
S. Pinel, Emmanuel Aman, F. Erblang, J. Dietrich +7 more
2014Journal of Controlled Release24 citations
Semantic Scholar
Synthesis, characterization, and gene transfer application of poly(ethylene glycol-b-ethylenimine) with high molar mass polyamine block.
Blandine Brissault, A. Kichler, Christian Leborgne, O. Danos +4 more
2006Biomacromolecules24 citations
Semantic Scholar
A new family of peptide–nucleic acid nanostructures with potent transfection activities
B. Bechinger, V. Vidovic, P. Bertani, A. Kichler
2011Journal of Peptide Science22 citations
Semantic Scholar
DNAJB2 expression in normal and diseased human and mouse skeletal muscle.
K. Claeys, M. Sozanska, Jean-Jacques Martin, E. Lacène +8 more
2010American Journal of Pathology22 citations Open access
Semantic Scholar
Infectivity enhancement of different HIV-1-based lentiviral pseudotypes in presence of the cationic amphipathic peptide LAH4-L1.
D. Fenard, Sandrine Genries, D. Scherman, A. Galy +2 more
2013Journal of Virological Methods20 citations Open access
Semantic Scholar
Identification of decorin derived peptides with a zinc dependent anti-myostatin activity.
S. Guiraud, L. van Wittenberghe, C. Georger, D. Scherman +1 more
2012Neuromuscular Disorders19 citations
Semantic Scholar
Polyarginine as a simultaneous antimicrobial, immunomodulatory and miRNA delivery agent within polyanionic hydrogels.
Varvara Gribova, Lauriane Petit, C. Seguin, S. Fournel +3 more
2022Macromolecular Bioscience18 citations
Semantic Scholar
Evaluation of the muscle gene transfer activity of a series of amphiphilic triblock copolymers
Debborah Alimi-Guez, C. Leborgne, Gaëlle Pembouong, L. van Wittenberghe +3 more
2009Journal of Gene Medicine18 citations
Semantic Scholar
GlycofectionTM in the presence of anionic fusogenic peptides: a study of the parameters affecting the peptide‒mediated enhancement of the transfection efficiency
A. Kichler, I. Freulon, V. Boutin, R. Mayer +2 more
1999Journal of Gene Medicine18 citations Open access
Semantic Scholar
Design of a new cell penetrating peptide for DNA, siRNA and mRNA delivery
S. Ali, Candice Dussouillez, B. Padilla, B. Frisch +2 more
2021Journal of Gene Medicine17 citations Open access
Semantic Scholar
Hybrid Cell-Penetrating Foldamer with Superior Intracellular Delivery Properties and Serum Stability.
C. Douat, Mégane Bornerie, S. Antunes, G. Guichard +1 more
2019Bioconjugate chemistry17 citations Open access
Semantic Scholar

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