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P. Escribá · SciRah

Researcher profile · Semantic Scholar

P. Escribá

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P. Escribá — researcher profile on SciRah

h-index: 46
Works: 199
Citations: 7,584

Most-cited papers

Membrane Lipid Composition: Effect on Membrane and Organelle Structure, Function and Compartmentalization and Therapeutic Avenues
Doralicia Casares, P. Escribá, C. A. Rosselló
2019International Journal of Molecular Sciences701 citations Open access
Semantic Scholar
Oleic acid content is responsible for the reduction in blood pressure induced by olive oil
Silvia Terés, G. Barceló-Coblijn, M. Benet, Rafael Álvarez +3 more
2008Proceedings of the National Academy of Sciences of the United States of America540 citations Open access
Semantic Scholar
The effect of natural and synthetic fatty acids on membrane structure, microdomain organization, cellular functions and human health.
M. Ibarguren, D. J. López, P. Escribá
2014Biochimica et Biophysica Acta289 citations Open access
Semantic Scholar
Membrane lipid therapy: Modulation of the cell membrane composition and structure as a molecular base for drug discovery and new disease treatment.
P. Escribá, X. Busquets, J. Inokuchi, G. Balogh +4 more
2015Progress in lipid research229 citations
Semantic Scholar
Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy
G. Barceló-Coblijn, M. L. Martin, R. D. de Almeida, M. A. Noguera-Salvà +6 more
2011Proceedings of the National Academy of Sciences of the United States of America165 citations Open access
Semantic Scholar
2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy
Silvia Terés, V. Lladó, Mónica Higuera, G. Barceló-Coblijn +9 more
2012Proceedings of the National Academy of Sciences of the United States of America110 citations Open access
Semantic Scholar
Regulation of the cancer cell membrane lipid composition by NaCHOleate: effects on cell signaling and therapeutical relevance in glioma.
V. Lladó, D. J. López, M. Ibarguren, M. Alonso +3 more
2014Biochimica et Biophysica Acta87 citations Open access
Semantic Scholar
Membrane-lipid therapy: A historical perspective of membrane-targeted therapies - From lipid bilayer structure to the pathophysiological regulation of cells.
P. Escribá
2017Biochimica et Biophysica Acta - Biomembranes86 citations Open access
Semantic Scholar
Structural basis of glycogen branching enzyme deficiency and pharmacologic rescue by rational peptide design
D. Froese, Amit Michaeli, T. McCorvie, T. Krojer +11 more
2015Human Molecular Genetics82 citations Open access
Semantic Scholar
Membrane lipid modifications and therapeutic effects mediated by hydroxydocosahexaenoic acid on Alzheimer's disease.
Manuel Torres, Samantha L. Price, M. A. Fiol-deRoque, Amaia Marcilla-Etxenike +12 more
2014Biochimica et Biophysica Acta71 citations Open access
Semantic Scholar
Cognitive recovery and restoration of cell proliferation in the dentate gyrus in the 5XFAD transgenic mice model of Alzheimer’s disease following 2-hydroxy-DHA treatment
M. A. Fiol-deRoque, R. Gutiérrez-Lanza, Silvia Terés, Manuel Torres +6 more
2013Biogerontology (Dordrecht)62 citations
Semantic Scholar
Lipids in Pathophysiology and Development of the Membrane Lipid Therapy: New Bioactive Lipids
Manuel Torres, S. Parets, Javier Fernández-Díaz, Roberto Beteta-Göbel +6 more
2021Membranes57 citations Open access
Semantic Scholar
Partitioning of liquid-ordered/liquid-disordered membrane microdomains induced by the fluidifying effect of 2-hydroxylated fatty acid derivatives.
M. Ibarguren, D. J. López, J. Encinar, J. González-Ros +2 more
2013Biochimica et Biophysica Acta57 citations Open access
Semantic Scholar
The role of membrane fatty acid remodeling in the antitumor mechanism of action of 2-hydroxyoleic acid.
M. L. Martin, G. Barceló-Coblijn, R. D. de Almeida, M. A. Noguera-Salvà +6 more
2013Biochimica et Biophysica Acta46 citations Open access
Semantic Scholar
Pivotal role of dihydrofolate reductase knockdown in the anticancer activity of 2-hydroxyoleic acid
V. Lladó, Silvia Terés, Mónica Higuera, R. Álvarez +4 more
2009Proceedings of the National Academy of Sciences of the United States of America44 citations Open access
Semantic Scholar
Guaiacol as a drug candidate for treating adult polyglucosan body disease.
O. Kakhlon, I. Ferreira, L. Solmesky, N. Khazanov +9 more
2018JCI Insight42 citations Open access
Semantic Scholar
2-Hydroxyoleic Acid Induces ER Stress and Autophagy in Various Human Glioma Cell Lines
Amaia Marcilla-Etxenike, M. L. Martin, M. A. Noguera-Salvà, J. García-Verdugo +4 more
2012PLoS ONE40 citations Open access
Semantic Scholar
Antimicrobial activity, membrane interaction and structural features of short arginine-rich antimicrobial peptides
Bruna Agrillo, Alessandra Porritiello, Lorena Gratino, M. Balestrieri +9 more
2023Frontiers in Microbiology38 citations Open access
Semantic Scholar
The Implications for Cells of the Lipid Switches Driven by Protein–Membrane Interactions and the Development of Membrane Lipid Therapy
Manuel Torres, C. A. Rosselló, P. Férnandez-García, V. Lladó +2 more
2020International Journal of Molecular Sciences36 citations Open access
Semantic Scholar
Changes in membrane organization upon spontaneous insertion of 2-hydroxylated unsaturated fatty acids in the lipid bilayer.
A. Khmelinskaia, M. Ibarguren, R. D. de Almeida, D. J. López +4 more
2014Langmuir34 citations Open access
Semantic Scholar
2-Hydroxy Arachidonic Acid: A New Non-Steroidal Anti-Inflammatory Drug
D. López, M. A. Fiol-deRoque, M. A. Noguera-Salvà, Silvia Terés +6 more
2013PLoS ONE33 citations Open access
Semantic Scholar
The Opposing Contribution of SMS1 and SMS2 to Glioma Progression and Their Value in the Therapeutic Response to 2OHOA
P. Férnandez-García, C. A. Rosselló, Raquel Rodríguez-Lorca, Roberto Beteta-Göbel +4 more
2019Cancers31 citations Open access
Semantic Scholar
Differential effect of 2-hydroxyoleic acid enantiomers on protein (sphingomyelin synthase) and lipid (membrane) targets.
Stefano Piotto, Simona Concilio, Erminia Bianchino, P. Iannelli +10 more
2014Biochimica et Biophysica Acta31 citations Open access
Semantic Scholar
Oral 2‐hydroxyoleic acid inhibits reflex hypersensitivity and open–field‐induced anxiety after spared nerve injury
G. Ávila-Martín, I. Galán-Arriero, Águeda Ferrer-Donato, Xavier Busquets +3 more
2015European Journal of Pain30 citations
Semantic Scholar
G protein-membrane interactions I: Gαi1 myristoyl and palmitoyl modifications in protein-lipid interactions and its implications in membrane microdomain localization.
Rafael Álvarez, D. J. López, J. Casas, V. Lladó +5 more
2015Biochimica et Biophysica Acta29 citations
Semantic Scholar
Membrane structure and function: relevance of lipid and protein structures in cellular physiology, pathology and therapy.
P. Escribá, G. Nicolson
2014Biochimica et Biophysica Acta29 citations Open access
Semantic Scholar
G protein-membrane interactions II: Effect of G protein-linked lipids on membrane structure and G protein-membrane interactions.
J. Casas, M. Ibarguren, Rafael Álvarez, Silvia Terés +6 more
2017Biochimica et Biophysica Acta - Biomembranes28 citations Open access
Semantic Scholar
Identification of Biomarkers of Necrosis in Xenografts Using Imaging Mass Spectrometry
Roberto Fernández, Jone Garate, Sergio Lage, Silvia Terés +7 more
2016Journal of the American Society for Mass Spectrometry27 citations Open access
Semantic Scholar
Interactions of fatty acids with phosphatidylethanolamine membranes: X-ray diffraction and molecular dynamics studies
A. Cordomí, J. Prades, J. Frau, O. Vögler +4 more
2010Journal of Lipid Research24 citations Open access
Semantic Scholar
The hydroxylated form of docosahexaenoic acid (DHA-H) modifies the brain lipid composition in a model of Alzheimer's disease, improving behavioral motor function and survival.
R. J. Mohaibes, M. A. Fiol-deRoque, Manuel Torres, Margarita Ordinas +4 more
2017Biochimica et Biophysica Acta - Biomembranes23 citations Open access
Semantic Scholar
Fundamentals of Membrane Lipid Replacement: A Natural Medicine Approach to Repairing Cellular Membranes and Reducing Fatigue, Pain, and Other Symptoms While Restoring Function in Chronic Illnesses and Aging
G. Nicolson, Gonzalo Ferreira de Mattos, M. Ash, R. Settineri +1 more
2021Membranes20 citations Open access
Semantic Scholar
The unfolded protein response in the therapeutic effect of hydroxy-DHA against Alzheimer’s disease
Manuel Torres, Amaia Marcilla-Etxenike, M. A. Fiol-deRoque, P. Escribá +1 more
2015Apoptosis19 citations
Semantic Scholar
Analysis of the Lipidome of Xenografts Using MALDI-IMS and UHPLC-ESI-QTOF
Roberto Fernández, Sergio Lage, B. Abad-García, G. Barceló-Coblijn +6 more
2014Journal of the American Society for Mass Spectrometry19 citations
Semantic Scholar
The triacylglycerol, hydroxytriolein, inhibits triple negative mammary breast cancer cell proliferation through a mechanism dependent on dihydroceramide and Akt
F. Guardiola-Serrano, Roberto Beteta-Göbel, Raquel Rodríguez-Lorca, M. Ibarguren +7 more
2019OncoTarget18 citations Open access
Semantic Scholar
Role of the C-terminal basic amino acids and the lipid anchor of the Gγ2 protein in membrane interactions and cell localization.
M. A. Noguera-Salvà, F. Guardiola-Serrano, M. L. Martín, Amaia Marcilla-Etxenike +3 more
2017Biochimica et Biophysica Acta - Biomembranes17 citations Open access
Semantic Scholar
Brain Lipids in the Pathophysiology and Treatment of Alzheimer’s Disease
Manuel Torres, X. Busquets, P. Escribá
201617 citations Open access
Semantic Scholar
The Antimicrobial Peptide 1018-K6 Interacts Distinctly with Eukaryotic and Bacterial Membranes, the Basis of Its Specificity and Bactericidal Activity
R. Ambrosio, C. A. Rosselló, Doralicia Casares, G. Palmieri +2 more
2022International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
Sustained activation of sphingomyelin synthase by 2-hydroxyoleic acid induces sphingolipidosis in tumor cells
M. L. Martin, G. Liebisch, S. Lehneis, G. Schmitz +8 more
2013Journal of Lipid Research16 citations Open access
Semantic Scholar
Normalization of sphingomyelin levels by 2-hydroxyoleic acid induces autophagic cell death of SF767 cancer cells
Silvia Terés, V. Lladó, Mónica Higuera, G. Barceló-Coblijn +9 more
2012Autophagy16 citations Open access
Semantic Scholar
Minerval (2-hydroxyoleic acid) causes cancer cell selective toxicity by uncoupling oxidative phosphorylation and compromising bioenergetic compensation capacity
Wessal Massalha, Mark Markovits, E. Pichinuk, Yael Feinstein-Rotkopf +6 more
2019Bioscience Reports15 citations Open access
Semantic Scholar
The Novel Anticancer Drug Hydroxytriolein Inhibits Lung Cancer Cell Proliferation via a Protein Kinase Cα– and Extracellular Signal-Regulated Kinase 1/2–Dependent Mechanism
F. Guardiola-Serrano, Roberto Beteta-Göbel, Raquel Rodríguez-Lorca, M. Ibarguren +6 more
2015Journal of Pharmacology and Experimental Therapeutics15 citations Open access
Semantic Scholar
A Phase 1/2A trial of idroxioleic acid: first-in-class sphingolipid regulator and glioma cell autophagy inducer with antitumor activity in refractory glioma
Juanita Lopez, J. Lai-Kwon, R. Molife, L. Welsh +16 more
2023British Journal of Cancer14 citations Open access
Semantic Scholar
2-hydroxyoleic acid affects cardiomyocyte [Ca2+]i transient and contractility in a region-dependent manner.
G. Borchert, M. Giggey, F. Kolář, Tak-Ming Wong +2 more
2008American Journal of Physiology. Heart and Circulatory Physiology12 citations
Semantic Scholar
Ternary copper(II) complexes with hippurate derivatives and 1,10-phenanthroline: Synthesis and biological activity
M. Barceló-Oliver, A. García-Raso, A. Terrón, E. Molins +7 more
200911 citations
Semantic Scholar
Triacylglycerol mimetics regulate membrane interactions of glycogen branching enzyme: implications for therapy[S]
Rafael Álvarez, J. Casas, D. J. López, M. Ibarguren +7 more
2017Journal of Lipid Research10 citations Open access
Semantic Scholar
Optimized Protocol To Analyze Changes in the Lipidome of Xenografts after Treatment with 2-Hydroxyoleic Acid
Roberto Fernández, Jone Garate, Sergio Lage, Silvia Terés +8 more
2015Analytical Chemistry10 citations Open access
Semantic Scholar
The Novel Antitumor Compound HCA Promotes Glioma Cell Death by Inducing Endoplasmic Reticulum Stress and Autophagy
Roberto Beteta-Göbel, Javier Fernández-Díaz, Laura Arbona-González, Raquel Rodríguez-Lorca +5 more
2021Cancers9 citations Open access
Semantic Scholar
2-Hydroxy-Docosahexaenoic Acid Is Converted Into Heneicosapentaenoic Acid via α-Oxidation: Implications for Alzheimer’s Disease Therapy
S. Parets, Á. Irigoyen, Margarita Ordinas, Joan Cabot +9 more
2020Frontiers in Cell and Developmental Biology9 citations Open access
Semantic Scholar
Evolving Diagnostic and Treatment Strategies for Pediatric CNS Tumors: The Impact of Lipid Metabolism
P. Férnandez-García, Gema Malet-Engra, Manuel Torres, Derek Hanson +4 more
2023Biomedicines8 citations Open access
Semantic Scholar
Treatment with albumin-hydroxyoleic acid complex restores sensorimotor function in rats with spinal cord injury: Efficacy and gene expression regulation
G. Ávila-Martín, Manuel Mata-Roig, I. Galán-Arriero, Julian S. Taylor +2 more
2017PLoS ONE8 citations Open access
Semantic Scholar

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X. Busquets×26
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Silvia Terés×16
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V. Lladó×15
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D. J. López×12
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G. Barceló-Coblijn

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F. Guardiola-Serrano×9

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M. A. Noguera-Salvà×8

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Mónica Higuera×8

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C. A. Rosselló×7

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