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M. Totsika · SciRah

Researcher profile · Semantic Scholar

M. Totsika

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M. Totsika — researcher profile on SciRah

h-index: 46
Works: 155
Citations: 7,286

Most-cited papers

Bacterial Biofilm Eradication Agents: A Current Review
Anthony D. Verderosa, M. Totsika, K. Fairfull‐Smith
2019Frontiers in Chemistry467 citations Open access
Semantic Scholar
The Complete Genome Sequence of Escherichia coli EC958: A High Quality Reference Sequence for the Globally Disseminated Multidrug Resistant E. coli O25b:H4-ST131 Clone
B. Forde, N. B. Ben Zakour, Mitchell Stanton-Cook, M. Phan +6 more
2014PLoS ONE140 citations Open access
Semantic Scholar
Oral Microbiome: A New Biomarker Reservoir for Oral and Oropharyngeal Cancers
Yenkai Lim, M. Totsika, M. Morrison, C. Punyadeera
2017Theranostics137 citations Open access
Semantic Scholar
The saliva microbiome profiles are minimally affected by collection method or DNA extraction protocols
Yenkai Lim, M. Totsika, M. Morrison, C. Punyadeera
2017Scientific Reports120 citations Open access
Semantic Scholar
Combination Therapies for Biofilm Inhibition and Eradication: A Comparative Review of Laboratory and Preclinical Studies
Sophia Hawas, Anthony D. Verderosa, M. Totsika
2022Frontiers in Cellular and Infection Microbiology113 citations Open access
Semantic Scholar
The Performance of an Oral Microbiome Biomarker Panel in Predicting Oral Cavity and Oropharyngeal Cancers
Yenkai Lim, N. Fukuma, M. Totsika, L. Kenny +2 more
2018Frontiers in Cellular and Infection Microbiology113 citations Open access
Semantic Scholar
Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli
K. Schaale, KM Peters, Ambika M. V. Murthy, AK Fritzsche +10 more
2015Mucosal Immunology74 citations Open access
Semantic Scholar
The co‐transcriptome of uropathogenic E scherichia coli‐infected mouse macrophages reveals new insights into host–pathogen interactions
Charalampos Mavromatis, N. J. Bokil, M. Totsika, Asha Kakkanat +8 more
2015Cellular Microbiology69 citations Open access
Semantic Scholar
Sortase A: an ideal target for anti-virulence drug development.
S. Cascioferro, M. Totsika, D. Schillaci
2014Microbial Pathogenesis69 citations Open access
Semantic Scholar
The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection
M. Shepherd, M. Achard, A. Idris, M. Totsika +11 more
2016Scientific Reports61 citations Open access
Semantic Scholar
Benefits and Challenges of Antivirulence Antimicrobials at the Dawn of the Post-Antibiotic Era
M. Totsika
2016Current Medicinal Chemistry61 citations Open access
Semantic Scholar
Intestinal Colonization Traits of Pandemic Multidrug-Resistant Escherichia coli ST131
Sohinee Sarkar, Melanie L. Hutton, D. Vagenas, R. Ruter +4 more
2018Journal of Infectious Diseases56 citations Open access
Semantic Scholar
Application of fragment-based screening to the design of inhibitors of Escherichia coli DsbA.
L. Adams, Pooja Sharma, B. Mohanty, O. Ilyichova +16 more
2015Angewandte Chemie54 citations Open access
Semantic Scholar
Disarming pathogens: benefits and challenges of antimicrobials that target bacterial virulence instead of growth and viability.
M. Totsika
2017Future Medicinal Chemistry53 citations Open access
Semantic Scholar
Comparative proteomics of uropathogenic Escherichia coli during growth in human urine identify UCA-like (UCL) fimbriae as an adherence factor involved in biofilm formation and binding to uroepithelial cells.
Daniël J. Wurpel, M. Totsika, L. Allsopp, R. Webb +2 more
2016Journal of Proteomics53 citations Open access
Semantic Scholar
F9 Fimbriae of Uropathogenic Escherichia coli Are Expressed at Low Temperature and Recognise Galβ1-3GlcNAc-Containing Glycans
Daniël J. Wurpel, M. Totsika, L. Allsopp, L. Hartley-Tassell +9 more
2014PLoS ONE46 citations Open access
Semantic Scholar
Comparative analysis of the uropathogenic Escherichia coli surface proteome by tandem mass-spectrometry of artificially induced outer membrane vesicles.
Daniël J. Wurpel, D. G. Moriel, M. Totsika, D. Easton +1 more
2015Journal of Proteomics43 citations
Semantic Scholar
Molecular Characterization of the Vacuolating Autotransporter Toxin in Uropathogenic Escherichia coli
K. Nichols, M. Totsika, D. G. Moriel, Alvin W. Lo +8 more
2016Journal of Bacteriology41 citations Open access
Semantic Scholar
The role of H4 flagella in Escherichia coli ST131 virulence
Asha Kakkanat, M. Totsika, Kolja Schaale, B. Duell +7 more
2015Scientific Reports38 citations Open access
Semantic Scholar
Development of 3D Printed Biodegradable Mesh with Antimicrobial Properties for Pelvic Organ Prolapse
Jiongyu Ren, R. Murray, C. Wong, Ji-Long Qin +6 more
2022Polymers34 citations Open access
Semantic Scholar
Biofilm formation by multidrug resistant Escherichia coli ST131 is dependent on type 1 fimbriae and assay conditions.
Sohinee Sarkar, D. Vagenas, M. Schembri, M. Totsika
2016Pathogens and Disease33 citations Open access
Semantic Scholar
YeeJ is an inverse autotransporter from Escherichia coli that binds to peptidoglycan and promotes biofilm formation
M. Martínez-Gil, K. Goh, E. Rackaityte, C. Sakamoto +6 more
2017Scientific Reports31 citations Open access
Semantic Scholar
Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens
M. Totsika, D. Vagenas, J. Paxman, Geqing Wang +5 more
2017Antioxidants and Redox Signaling31 citations Open access
Semantic Scholar
Molecular Analysis of Asymptomatic Bacteriuria Escherichia coli Strain VR50 Reveals Adaptation to the Urinary Tract by Gene Acquisition
S. Beatson, N. B. Ben Zakour, M. Totsika, B. Forde +19 more
2015Infection and Immunity30 citations Open access
Semantic Scholar
Rapid elaboration of fragments into leads by X-ray crystallographic screening of parallel chemical libraries (REFiLx).
M. Bentley, O. Ilyichova, Geqing Wang, Martin L. Williams +11 more
2020Journal of Medicinal Chemistry26 citations Open access
Semantic Scholar
Chemoradiation therapy changes oral microbiome and metabolomic profiles in patients with oral cavity cancer and oropharyngeal cancer
Yenkai Lim, Kai D. Tang, A. Karpe, D. Beale +4 more
2021Head and Neck25 citations Open access
Semantic Scholar
Nitroxide Functionalized Antibiotics Are Promising Eradication Agents against Staphylococcus aureus Biofilms
Anthony D. Verderosa, R. Dhouib, K. Fairfull‐Smith, M. Totsika
2019Antimicrobial Agents and Chemotherapy25 citations Open access
Semantic Scholar
The Wzi outer membrane protein mediates assembly of a tight capsular polysaccharide layer on the Acinetobacter baumannii cell surface
Jacob Tickner, Sophia Hawas, M. Totsika, J. Kenyon
2021Scientific Reports23 citations Open access
Semantic Scholar
A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance
E. Furlong, Alvin W. Lo, F. Kurth, L. Premkumar +8 more
2017Nature Communications23 citations Open access
Semantic Scholar
Comprehensive analysis of type 1 fimbriae regulation in fimB‐null strains from the multidrug resistant Escherichia coli ST131 clone
Sohinee Sarkar, L. Roberts, M. Phan, Lendl Tan +8 more
2016Molecular Microbiology22 citations Open access
Semantic Scholar
Differential Afa/Dr Fimbriae Expression in the Multidrug-Resistant Escherichia coli ST131 Clone
L. Álvarez-Fraga, M. Phan, K. Goh, N. Nguyen +10 more
2022mBio21 citations Open access
Semantic Scholar
A method for increasing electroporation competence of Gram-negative clinical isolates by polymyxin B nonapeptide
Ji-Long Qin, Yaoqin Hong, Karthik Pullela, R. Morona +2 more
2022Scientific Reports20 citations Open access
Semantic Scholar
Structural bioinformatic analysis of DsbA proteins and their pathogenicity associated substrates
Carlos Santos-Martín, Geqing Wang, P. Subedi, L. Hor +3 more
2021Computational and Structural Biotechnology Journal19 citations Open access
Semantic Scholar
O antigen biogenesis sensitises Escherichia coli K-12 to bile salts, providing a plausible explanation for its evolutionary loss
Ji-Long Qin, Yaoqin Hong, Renato Morona, M. Totsika
2023PLoS Genetics17 citations Open access
Semantic Scholar
Variation of Antigen 43 self-association modulates bacterial compacting within aggregates and biofilms
Julieanne L. Vo, Gabriela C. Martinez-Ortiz, M. Totsika, Alvin W. Lo +10 more
2022npj Biofilms and Microbiomes17 citations Open access
Semantic Scholar
Moraxella catarrhalis NucM is an entry nuclease involved in extracellular DNA and RNA degradation, cell competence and biofilm scaffolding
A. Tan, Wing-Sze Li, Anthony D. Verderosa, Luke V. Blakeway +3 more
2019Scientific Reports17 citations Open access
Semantic Scholar
Repeat-Unit Elongations To Produce Bacterial Complex Long Polysaccharide Chains, an O-Antigen Perspective
Yaoqin Hong, Dalong Hu, Anthony D. Verderosa, Ji-Long Qin +2 more
2023EcoSal Plus16 citations Open access
Semantic Scholar
Loss of β-Ketoacyl Acyl Carrier Protein Synthase III Activity Restores Multidrug-Resistant Escherichia coli Sensitivity to Previously Ineffective Antibiotics
Yaoqin Hong, Ji-Long Qin, Anthony D. Verderosa, Sophia Hawas +4 more
2022bioRxiv16 citations Open access
Semantic Scholar
Isothiazolone–Nitroxide Hybrids with Activity against Antibiotic-Resistant Staphylococcus aureus Biofilms
Anthony D. Verderosa, Sophia Hawas, J. Harris, M. Totsika +1 more
2022ACS Omega16 citations Open access
Semantic Scholar
An in vitro Reconstructed Human Skin Equivalent Model to Study the Role of Skin Integration Around Percutaneous Devices Against Bacterial Infection
Eleonore C. L. Bolle, Anthony D. Verderosa, R. Dhouib, T. Parker +3 more
2020Frontiers in Microbiology16 citations Open access
Semantic Scholar
Extensive Diversity in Escherichia coli Group 3 Capsules Is Driven by Recombination and Plasmid Transfer from Multiple Species
Yaoqin Hong, Ji-Long Qin, Xavier Bertran Forga, M. Totsika
2023bioRxiv13 citations Open access
Semantic Scholar
Conserved FimH mutations in the global Escherichia coli ST131 multi-drug resistant lineage weaken interdomain interactions and alter adhesin function
Ji-Long Qin, K. Wilson, Sohinee Sarkar, B. Heras +2 more
2022Computational and Structural Biotechnology Journal13 citations Open access
Semantic Scholar
A high-throughput cell-based assay pipeline for the preclinical development of bacterial DsbA inhibitors as antivirulence therapeutics
Anthony D. Verderosa, R. Dhouib, Yaoqin Hong, Taylah K Anderson +2 more
2021Scientific Reports13 citations Open access
Semantic Scholar
Profluorescent Fluoroquinolone-Nitroxides for Investigating Antibiotic–Bacterial Interactions
Anthony D. Verderosa, R. Dhouib, K. Fairfull‐Smith, M. Totsika
2019Antibiotics13 citations Open access
Semantic Scholar
Differential Regulation of the Surface-Exposed and Secreted SslE Lipoprotein in Extraintestinal Pathogenic Escherichia coli
Lendl Tan, D. G. Moriel, M. Totsika, S. Beatson +1 more
2016PLoS ONE13 citations Open access
Semantic Scholar
Thermoresponsive Polymer-Antibiotic Conjugates Based on Gradient Copolymers of 2-Oxazoline and 2-Oxazine.
Jong-Ryul Park, Anthony D. Verderosa, M. Totsika, R. Hoogenboom +1 more
2021Biomacromolecules12 citations Open access
Semantic Scholar
Eradicating uropathogenic Escherichia coli biofilms with a ciprofloxacin-dinitroxide conjugate.
Anthony D. Verderosa, Jessica P Harris, R. Dhouib, M. Totsika +1 more
2019MedChemComm12 citations Open access
Semantic Scholar
Co-Occurrence of Multidrug Resistant Klebsiella pneumoniae Pathogenic Clones of Human Relevance in an Equine Pneumonia Case
C. Venturini, B. Bowring, S. Partridge, N. B. Ben Zakour +7 more
2022Microbiology spectrum10 citations Open access
Semantic Scholar
Salmonella enterica BcfH Is a Trimeric Thioredoxin-Like Bifunctional Enzyme with Both Thiol Oxidase and Disulfide Isomerase Activities
P. Subedi, J. Paxman, Geqing Wang, L. Hor +8 more
2021Antioxidants and Redox Signaling10 citations Open access
Semantic Scholar
Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds.
Luke F Duncan, Geqing Wang, O. Ilyichova, R. Dhouib +4 more
2021Bioorganic & Medicinal Chemistry9 citations Open access
Semantic Scholar

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