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N. Takeguchi · SciRah

Researcher profile · Semantic Scholar

N. Takeguchi

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N. Takeguchi — researcher profile on SciRah

h-index: 27
Works: 137
Citations: 1,928

Most-cited papers

Specific localization of an inwardly rectifying K+ channel, Kir4.1, at the apical membrane of rat gastric parietal cells; its possible involvement in K+ recycling for the H+‐K+‐pump
A. Fujita, Y. Horio, K. Higashi, T. Mouri +3 more
2002Journal of Physiology94 citations Open access
Semantic Scholar
Up‐regulation of Na+,K+‐ATPase α3‐isoform and down‐regulation of the α1‐isoform in human colorectal cancer
H. Sakai, Tomoyuki Suzuki, M. Maeda, Y. Takahashi +4 more
200493 citations Open access
Semantic Scholar
Upregulation of thromboxane synthase in human colorectal carcinoma and the cancer cell proliferation by thromboxane A2
H. Sakai, Tomoyuki Suzuki, Y. Takahashi, M. Ukai +8 more
2006FEBS Letters79 citations Open access
Semantic Scholar
Involvement of aquaporin-5 in differentiation of human gastric cancer cells
Tomoko Watanabe, Takuto Fujii, Takeshi Oya, N. Horikawa +6 more
2009Journal of Physiological Sciences66 citations Open access
Semantic Scholar
Functional Expression of Gastric H+,K+-ATPase and Site-directed Mutagenesis of the Putative Cation Binding Site and the Catalytic Center (*)
S. Asano, Y. Tega, K. Konishi, M. Fujioka +1 more
1996Journal of Biological Chemistry65 citations Open access
Semantic Scholar
Up-regulation of Na(+),K(+)-ATPase alpha 3-isoform and down-regulation of the alpha1-isoform in human colorectal cancer.
H. Sakai, Tomoyuki Suzuki, M. Maeda, Y. Takahashi +4 more
2004FEBS Letters63 citations
Semantic Scholar
Identification of genes responsive to sodium butyrate in colonic epithelial cells.
Y. Tabuchi, Y. Arai, T. Kondo, N. Takeguchi +1 more
2002Biochemical and Biophysical Research Communications - BBRC59 citations
Semantic Scholar
Functional expression of putative H+-K+-ATPase from guinea pig distal colon.
S. Asano, S. Hoshina, Y. Nakaie, Toshiyuki Watanabe +3 more
1998American Journal of Physiology - Cell Physiology48 citations
Semantic Scholar
Functional Association between K+-Cl- Cotransporter-4 and H+,K+-ATPase in the Apical Canalicular Membrane of Gastric Parietal Cells*
Takuto Fujii, Y. Takahashi, Akira Ikari, M. Morii +4 more
2009Journal of Biological Chemistry43 citations Open access
Semantic Scholar
The Cavity Structure for Docking the K+-competitive Inhibitors in the Gastric Proton Pump*
S. Asano, A. Yoshida, H. Yashiro, Y. Kobayashi +4 more
2004Journal of Biological Chemistry43 citations Open access
Semantic Scholar
The Roles of Carbohydrate Chains of the β-Subunit on the Functional Expression of Gastric H+,K+-ATPase*
S. Asano, K. Kawada, T. Kimura, A. Grishin +2 more
2000Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Thromboxane A2, released by the anti‐ tumour drug irinotecan, is a novel stimulator of Cl− secretion in isolated rat colon
H. Sakai, Takahiro Sato, Noriko Hamada, Miyuki Yasue +3 more
1997Journal of Physiology42 citations Open access
Semantic Scholar
Mutational Analysis of Putative SCH 28080 Binding Sites of the Gastric H+,K+-ATPase*
S. Asano, Saiko Matsuda, Y. Tega, Kanae Shimizu +2 more
1997Journal of Biological Chemistry41 citations Open access
Semantic Scholar
K+-Cl- Cotransporter-3a Up-regulates Na+,K+-ATPase in Lipid Rafts of Gastric Luminal Parietal Cells*
Takuto Fujii, Y. Takahashi, Y. Itomi, Kyosuke Fujita +6 more
2008Journal of Biological Chemistry40 citations Open access
Semantic Scholar
A Gastric Housekeeping Cl− Channel Activated via Prostaglandin EP3 Receptor-mediated Ca2+/Nitric Oxide/cGMP Pathway (*)
H. Sakai, E. Kumano, Akira Ikari, N. Takeguchi
1995Journal of Biological Chemistry34 citations Open access
Semantic Scholar
Proton-Potassium (H(+)/K(+)) ATPases: Properties and Roles in Health and Diseases.
H. Sakai, Takuto Fujii, N. Takeguchi
2016Metal ions in life sciences29 citations
Semantic Scholar
Molecular and pharmacological properties of inwardly rectifying K+ channels of human lung cancer cells.
H. Sakai, Takahiro Shimizu, Katsuhito Hori, Akira Ikari +2 more
2002European Journal of Pharmacology29 citations
Semantic Scholar
The proton pump inhibitor, E3810, binds to the N-terminal half of the α-subunit of gastric H+,K+-ATPase
M. Morii, K. Hamatani, N. Takeguchi
199529 citations
Semantic Scholar
Is the ClC‐2 chloride channel involved in the Cl− secretory mechanism of gastric parietal cells?
Katsuhito Hori, Y. Takahashi, N. Horikawa, T. Furukawa +3 more
2004FEBS Letters28 citations
Semantic Scholar
A Chimeric Gastric H+,K+-ATPase Inhibitable with Both Ouabain and SCH 28080*
S. Asano, Saiko Matsuda, S. Hoshina, Shinya Sakamoto +1 more
1999Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Prostaglandin E2-Activated Housekeeping Cl- Channels in the Basolateral Membrane of Rat Gastric Parietal Cells
Akira Ikari, H. Sakai, A. Tanaka, A. Ikeda +2 more
199927 citations Open access
Semantic Scholar
Inhibition of gastric H+,K+-ATPase by 4-(2-butyl-6,7-dichloro-2-cyclopentylindan-1-on-5-yl)oxybutyric acid (DCPIB), an inhibitor of volume-regulated anion channel.
Takuto Fujii, Y. Takahashi, H. Takeshima, Chisato Saitoh +3 more
2015European Journal of Pharmacology26 citations
Semantic Scholar
Alanine-scanning Mutagenesis of the Sixth Transmembrane Segment of Gastric H+,K+-ATPase α-Subunit*
S. Asano, Toshiro Io, T. Kimura, Shinya Sakamoto +1 more
2001Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Mutational Study on the Roles of Disulfide Bonds in the β-Subunit of Gastric H+,K+-ATPase*
Tohru Kimura, Y. Tabuchi, N. Takeguchi, S. Asano
2002Journal of Biological Chemistry21 citations Open access
Semantic Scholar
The Phospholipid Flippase Activity of Gastric Vesicles*
Hidehiro Suzuki, Masahiro Kamakura, M. Morii, N. Takeguchi
1997Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Development and characterization of conditionally immortalized gastric epithelial cell lines from transgenic rats harboring temperature-sensitive simian virus 40 large T-antigen gene.
Y. Tabuchi, Y. Arai, S. Ohta, Hiroki Shioya +5 more
2002Cell Structure and Function20 citations Open access
Semantic Scholar
Expression of ATP1AL1, a non-gastric proton pump, in human colorectum.
Y. Takahashi, H. Sakai, Mutsuko Kuragari, Tomoyuki Suzuki +5 more
2002The Japanese Journal of Physiology19 citations Open access
Semantic Scholar
Involvement of the H3O+-Lys-164 -Gln-161-Glu-345 Charge Transfer Pathway in Proton Transport of Gastric H+,K+-ATPase*
M. Morii, M. Yamauchi, T. Ichikawa, Takuto Fujii +4 more
2008Journal of Biological Chemistry18 citations Open access
Semantic Scholar
Function of K⁺-Cl⁻ cotransporters in the acid secretory mechanism of gastric parietal cells.
Takuto Fujii, Kyosuke Fujita, N. Takeguchi, H. Sakai
2011Biological and Pharmaceutical Bulletin16 citations Open access
Semantic Scholar
Inhibition of P-type ATPases by [(dihydroindenyl)oxy]acetic acid (DIOA), a K+ -Cl- cotransporter inhibitor.
Takuto Fujii, Y. Ohira, Y. Itomi, Y. Takahashi +4 more
2007European Journal of Pharmacology16 citations
Semantic Scholar
Oligomeric Regulation of Gastric H,K-ATPase (*)
M. Morii, Yuiko Hayata, K. Mizoguchi, N. Takeguchi
1996Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Molecular and cellular regulation of the gastric proton pump.
S. Asano, M. Morii, N. Takeguchi
2004Biological and Pharmaceutical Bulletin14 citations Open access
Semantic Scholar
Nitric oxide‐induced Cl− secretion in isolated rat colon is mediated by the release of thromboxane A2
H. Sakai, Tomoyuki Suzuki, M. Murota, Y. Takahashi +1 more
2002Journal of Physiology14 citations Open access
Semantic Scholar
Stable expression of gastric proton pump activity at the cell surface.
Tohru Kimura, A. Yoshida, Y. Tabuchi, Akira Ikari +2 more
2002Journal of Biochemistry (Tokyo)13 citations
Semantic Scholar
The NH(2)-terminus of K(+)-Cl(-) cotransporter 3a is essential for up-regulation of Na(+),K(+)-ATPase activity.
Takuto Fujii, Kyosuke Fujita, Takahiro Shimizu, N. Takeguchi +1 more
2010Biochemical and Biophysical Research Communications - BBRC12 citations
Semantic Scholar
Cyclic AMP‐dependent Cl− secretion induced by thromboxane A2 in isolated human colon
N. Horikawa, Tomoyuki Suzuki, T. Uchiumi, T. Minamimura +3 more
2005Journal of Physiology12 citations
Semantic Scholar
ATP, thapsigargin and cAMP increase Ca2+ in rat hepatocytes by activating three different Ca2+ influx pathways.
A. Ikari, Hideki Sakai, N. Takeguchi
1997The Japanese Journal of Physiology11 citations Open access
Semantic Scholar
The proton pump inhibitor, E3810, binds to the N-terminal half of the alpha-subunit of gastric H+,K(+)-ATPase.
M. Morii, K. Hamatani, N. Takeguchi
1995Biochemical Pharmacology11 citations
Semantic Scholar
E3040 sulphate, a novel thromboxane synthase inhibitor, blocks the Cl− secretion induced by platelet‐activating factor in isolated rat colon
H. Sakai, Tomoyuki Suzuki, M. Murota, K. Oketani +3 more
2002British Journal of Pharmacology10 citations Open access
Semantic Scholar
Inhibition of ecto-ATPase activity by curcumin in hepatocellular carcinoma HepG2 cells
Takuto Fujii, Taku Minagawa, Takahiro Shimizu, N. Takeguchi +1 more
2011Journal of Physiological Sciences9 citations Open access
Semantic Scholar
Chimeric Domain Analysis of the Compatibility between H+,K+-ATPase and Na+,K+-ATPase β-Subunits for the Functional Expression of Gastric H+,K+-ATPase*
S. Asano, T. Kimura, S. Ueno, M. Kawamura +1 more
1999Journal of Biological Chemistry9 citations Open access
Semantic Scholar
Fluorine-free Word Line Molybdenum Process for Enhancing Scalability and Reliability in 3D Flash Memory
T. Fukushima, T. Kashima, S. Seto, H. Ohtori +23 more
20242024 IEEE Symposium on VLSI Technology and Circuits (VLSI Technology and Circuits)6 citations
Semantic Scholar
Overexpression of heat shock protein 70 restores the structural stability and functional defects of temperature-sensitive mutant of large T antigen at nonpermissive temperature
Y. Tabuchi, Ryosuke Kuribayashi, Ichiro Takasaki, T. Doi +4 more
2006Cell stress & chaperones (Print)6 citations Open access
Semantic Scholar
Inhibition of small‐conductance Cl− channels by the interleukin‐1β‐stimulated production of superoxide in rabbit gastric parietal cells
H. Sakai, Y. Ohira, A. Tanaka, Tomoyuki Suzuki +3 more
2003Journal of Physiology6 citations
Semantic Scholar
A cyclic GMP‐dependent housekeeping Cl− channel in rabbit gastric parietal cells activated by a vasodilator ecabapide
H. Sakai, Akira Ikari, Eiichi Kumano, N. Takeguchi
1996British Journal of Pharmacology6 citations Open access
Semantic Scholar
Leukotrienes-mediated effects of water extracts from Sargassum horneri, a marine brown alga, on Cl- absorption in isolated rat colon.
H. Sakai, T. Uchiumi, Jung-Bum Lee, Y. Ohira +4 more
2004The Japanese Journal of Physiology5 citations Open access
Semantic Scholar
New Gastric Epithelial Cell Lines from Mice Transgenic for Temperature-Sensitive Simian Virus 40 Large T Antigen Show Distinct Types of Cell Differentiation
Y. Tabuchi, Y. Arai, Hiroki Shioya, Ryosuke Kuribayashi +5 more
2003Digestion5 citations
Semantic Scholar
[Application of personal drug (P-drug) seminar to clinical pharmacy education in the graduate school of pharmaceutical sciences].
J. Kawakami, Yasuhiko Mimura, I. Adachi, N. Takeguchi
2002Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan5 citations Open access
Semantic Scholar
Development of Concept N-MHTM Headbox
T. Makino, N. Takeguchi, Akira Eguchi, Toshimi Tajima
19945 citations Open access
Semantic Scholar
Quantity and quality control of gastric proton pump in the endoplasmic reticulum by ubiquitin/proteasome system.
Tohru Kimura, H. Ishizuka, A. Yoshida, M. Morii +2 more
2003Biochemistry4 citations
Semantic Scholar

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H. Sakai×26
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H. Sakai — researcher profile on SciRah
S. Asano×20
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M. Morii×14
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Y. Takahashi×12
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Akira Ikari — researcher profile on SciRah

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N. Horikawa — researcher profile on SciRah

T. Minamimura×5

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T. Minamimura — researcher profile on SciRah

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Takahiro Shimizu — researcher profile on SciRah