L. Gien

Most-cited papers

1. Pembrolizumab plus Chemotherapy in Advanced Endometrial Cancer

   R. Eskander, M. Sill, L. Beffa, R. Moore +23 more

   2023New England Journal of Medicine625 citations Open access

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2. Pembrolizumab plus chemotherapy in advanced or recurrent endometrial cancer: overall survival and exploratory analyses of the NRG GY018 phase 3 randomized trial

   R. Eskander, M. Sill, L. Beffa, R. Moore +23 more

   2025Nature Medicine82 citations Open access

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3. Clinical Validation of Human Papilloma Virus Circulating Tumor DNA for Early Detection of Residual Disease After Chemoradiation in Cervical Cancer

   K. Han, J. Zou, Zhen Zhao, Z. Baskurt +17 more

   2023Journal of Clinical Oncology68 citations Open access

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4. A randomized phase III, two-arm trial of paclitaxel, carboplatin, and maintenance letrozole versus letrozole monotherapy in patients with stage II-IV, primary low-grade serous carcinoma of the ovary or peritoneum.

   Amanda Nickles Fader, L. Gien, A. Miller, Al Covens +1 more

   2021Journal of Clinical Oncology63 citations

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5. Quality-of-Life Outcomes and Toxic Effects Among Patients With Cancers of the Uterus Treated With Stereotactic Pelvic Adjuvant Radiation Therapy: The SPARTACUS Phase 1/2 Nonrandomized Controlled Trial.

   E. Leung, A. Gladwish, M. Davidson, A. Taggar +14 more

   2022JAMA Oncology26 citations Open access

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6. Mismatch-repair deficiency, microsatellite instability, and lynch syndrome in ovarian cancer: A systematic review and meta-analysis.

   Cristina Mitric, Lina Salman, L. Abrahamyan, S. Kim +4 more

   2023Gynecologic Oncology25 citations

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7. Phase II Trial of Pembrolizumab and Epacadostat in Recurrent Clear Cell Carcinoma of the Ovary: an NRG Oncology Study GY016

   L. Gien, Danielle M. Enserro, M. Block, S. Waggoner +12 more

   2024Gynecologic Oncology19 citations Open access

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8. Phase II activity trial of high dose radiation and chemosensitization in patients with macrometastatic lymph node spread after sentinel node biopsy in vulvar cancer: Groningen International Study on Sentinel Nodes in Vulvar Cancer III (GROINSS-V III/ NRG-GY024)

   L. Gien, B. Slomovitz, A. V. D. van der Zee, Maaike H. M. Oonk

   2023International Journal of Gynecological Cancer19 citations Open access

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9. Cervical conization and lymph node assessment for early stage low-risk cervical cancer

   A. Nica, Z. Marchocki, L. Gien, R. Kupets +2 more

   2021International Journal of Gynecological Cancer19 citations Open access

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10. Impact of care by gynecologic oncologists on primary ovarian cancer survival: A population-based study.

    G. Bouchard-Fortier, L. Gien, R. Sutradhar, W. Chan +3 more

    2022Gynecologic Oncology15 citations

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11. Apixaban for extended postoperative thromboprophylaxis in gynecologic oncology patients undergoing laparotomy.

    E. Spénard, W. Geerts, Yulia Lin, L. Gien +3 more

    2023Gynecologic Oncology14 citations

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12. A prospective comparison of costs between robotics, laparoscopy, and laparotomy in endometrial cancer among women with Class III obesity or higher

    S. Kosa, S. Ferguson, T. Panzarella, S. Lau +7 more

    2021Journal of Surgical Oncology14 citations

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13. The accuracy of intraoperative frozen section examination of sentinel lymph nodes in squamous cell cancer of the vulva.

    B. Swift, Melissa Tigert, A. Nica, Al Covens +5 more

    2021Gynecologic Oncology13 citations

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14. Pre-operative wait times in high-grade non-endometrioid endometrial cancer: Do surgical delays impact patient survival?

    A. Nica, R. Sutradhar, R. Kupets, A. Covens +4 more

    2021Gynecologic Oncology10 citations

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15. The use of indocyanine green (ICG) for sentinel lymph node detection in vulvar cancer.

    K. Cornel, Meera P Mehta, B. Swift, Al Covens +3 more

    2025Gynecologic Oncology9 citations

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16. Role of HPV in the prediction of persistence/recurrence after treatment for cervical precancer.

    A. Kulkarni, A. Covens, N. Durand, Z. Ghorab +4 more

    2023Journal of Obstetrics and Gynaecology Canada9 citations

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17. Lymphadenectomy for high-grade endometrial cancer: Does it impact lymph node recurrence?

    B. Swift, L. Philp, E. Atenafu, N. Malkani +2 more

    2021European Journal of Surgical Oncology9 citations

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18. Advances in Vulvar Cancer Biology and Management

    Rania Chehade, K. Jerzak, Farideh Tavanger, A. Plotkin +3 more

    2024Journal of Clinical Oncology8 citations

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19. Impact of lymphadenectomy and intra-operative tumor rupture on survival in early-stage mucinous ovarian cancers

    S. Kim, A. Madariaga, L. Hogen, D. Vicus +4 more

    2023International Journal of Gynecological Cancer8 citations Open access

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20. Incorporating Molecular Diagnostics into Treatment Paradigms for Endometrial Cancer

    B. Swift, L. Gien

    2022Current Treatment Options in Oncology7 citations

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21. A randomized, phase III study of sacituzumab govitecan versus treatment of the physician's choice in patients with endometrial cancer after platinum-based chemotherapy and immunotherapy: the ASCENT-GYN-01 study (GOG-3104/ENGOT-en26/APGOT-EN2).

    R. Eskander, B. Corr, D. Cibula, D. Tan +15 more

    2025International Journal of Gynecological Cancer6 citations Open access

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22. Assessing para‐aortic nodal status in high‐grade endometrial cancer patients with negative pelvic sentinel lymph node biopsy

    A. Benseler, D. Vicus, A. Covens, R. Kupets +2 more

    2024International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics6 citations Open access

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23. Overall survival and progression-free survival by PD-L1 status among endometrial cancer patients treated with pembrolizumab plus carboplatin/paclitaxel as compared to carboplatin/paclitaxel plus placebo in the NRG GY018 trial

    R. Eskander, M. Sill, L. Beffa, R. Moore +21 more

    2024Gynecologic Oncology6 citations

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24. Updated overall survival analysis and examination of subsequent therapy in endometrial cancer (EC) patients (pts) treated with pembrolizumab plus carboplatin/paclitaxel (CP) as compared to CP plus placebo (PBO) in the NRG-GY018 trial.

    R. N. Eskander, M. Sill, Lindsey Beffa, Richard G. Moore +16 more

    2026Journal of Clinical Oncology5 citations

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25. Hormone maintenance therapy for women with low-grade serous ovarian cancer in the front-line setting: A systematic review.

    Caitlin Lazurko, M. Clark, K. Pulman, G. Lennox +4 more

    2021Gynecologic Oncology5 citations

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26. Optimizing the screening and management of preoperative anemia prior to gynecologic oncology surgery (OPRA1): A quality improvement initiative.

    E. Spénard, Yulia Lin, Al Covens, L. Gien +5 more

    2025Gynecologic Oncology4 citations

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27. Management of inguinal lymph nodes in locally advanced, surgically unresectable, squamous cell carcinoma of the vulva.

    B. Swift, L. Khoja, Joanna Matthews, J. Croke +3 more

    2024Gynecologic Oncology4 citations Open access

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28. Safety of fertility sparing management in invasive mucinous ovarian carcinoma.

    S. Kim, A. Madariaga, L. Hogen, D. Vicus +4 more

    2023Gynecologic Oncology4 citations

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29. A Pan-Canadian Consensus Statement on First-Line PARP Inhibitor Maintenance for Advanced, High-Grade Serous and Endometrioid Tubal, Ovarian, and Primary Peritoneal Cancers

    A. Tinker, A. Altman, M. Bernardini, P. Ghatage +5 more

    2022Current Oncology4 citations Open access

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30. Does radical hysterectomy for clinically apparent stage II endometrial cancer affect risk of local recurrence?

    G. Lennox, M. Clark, T. Zigras, M. Rouzbahman +3 more

    2021Journal of Obstetrics and Gynaecology Canada4 citations

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31. Results of a randomized phase III trial of letrozole alone versus paclitaxel and carboplatin followed by letrozole as initial treatment for patients with stage II-IV ovarian, fallopian tube, or primary peritoneal low-grade serous carcinoma (NRG-GY019, NCT04095364)

    A. Fader, A. Miller, L. Gien, A. Deery +21 more

    2026Gynecologic Oncology3 citations

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32. Effect of fragmentation of surgery and adjuvant treatment in high-grade non-endometrioid endometrial cancer: a population-based cohort study.

    A. Nica, R. Sutradhar, R. Kupets, A. Covens +4 more

    2024American Journal of Obstetrics and Gynecology3 citations

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33. Cancer surgery cancellation: incidence, outcomes and recovery in a universal health care system

    A. Eskander, C. Zanchetta, N. Coburn, D. Enepekides +7 more

    2022Canadian journal of surgery. Journal canadien de chirurgie3 citations Open access

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34. Feasibility and recurrence risk of sentinel lymph node biopsy in large vulvar tumors (≥4 cm).

    Stephanie Gill, K. Cornel, Isabella Aversa, Brenna E. Swift +4 more

    2026International Journal of Gynecological Cancer2 citations Open access

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35. Rates of genetic consultation in high‐grade serous ovarian cancer patients in the era of PARP inhibitor therapy: A population‐based study

    Shannon E Brent, Jacob McGee, D. Vicus, Raymond Kim +3 more

    2024International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2 citations Open access

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36. Efficacy and safety study of a novel alpha-fetoprotein (AFP)-maytansine conjugate in an ovarian xenograft model.

    I. Sherman, W. Hill, Patricia Griffin, D. Andrews +5 more

    2023Journal of Clinical Oncology2 citations Open access

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37. O014/#415 Phase II trial of pembrolizumab and epacadostat in recurrent clear cell carcinoma of the ovary: an NRG oncology study

    L. Gien, Danielle M. Enserro, M. Block, S. Waggoner +12 more

    2022Oral Abstracts (Regular and Late-Breaking Submission)2 citations Open access

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38. Association of Surgical Approach with Oncologic Outcomes in Low-Risk Cervical Cancer.

    M. Cusimano, Amanda Poxon, L. Gien, R. Sutradhar +7 more

    2026American Journal of Obstetrics and Gynecology1 citations Open access

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39. Patterns of care of gestational trophoblastic disease in Ontario: a population-based study.

    G. Bouchard-Fortier, Z. Ante, Ning Liu, Al Covens +5 more

    2026International Journal of Gynecological Cancer1 citations

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40. What Are the Current HPV Types Contributing to Cervical High Grade Squamous Intraepithelial Lesion, Adenocarcinoma in Situ, and Early Cervical Cancer?

    Lina Salman, L. Gien, D. Vicus, Michael Shier +5 more

    2025Journal of Obstetrics and Gynaecology Canada1 citations Open access

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41. The Relation Between Post-Operative Surgical Site Infection and Time to Start Adjuvant Treatment in Ovarian and Uterine Cancers

    K. Cornel, Julie My Van Nguyen, L. Gien, A. Covens +1 more

    2025Current Oncology1 citations Open access

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42. The impact of perioperative transfusions on the oncologic outcomes of patients with ovarian cancer: A population‐based study

    G. Bouchard-Fortier, L. Gien, W. C. Chan, Yulia Lin +2 more

    2024Journal of Surgical Oncology1 citations Open access

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43. Postoperative Complications in Elderly Patients Undergoing Surgery for Ovarian Cancer: A NSQIP Analysis

    Lina Salman, A. Covens, L. Gien, D. Vicus

    2024Journal of Surgical Oncology1 citations

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44. Timing of Palliative Care Initiation and Resource Use-Are We Any Further Ahead?

    Ada Hsieh, L. Gien

    2024JAMA Network Open1 citations Open access

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45. Pembrolizumab versus placebo in addition to carboplatin and paclitaxel for measurable stage 3 or 4a, stage 4b or recurrent endometrial cancer: The phase 3, NRG GY018 study (LBA 10)

    R. Eskander, M. Sill, L. Beffa, R. Moore +21 more

    2023Gynecologic Oncology1 citations

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46. The use of Indocyanine Green (ICG) for sentinel lymph node detection in vulvar cancer (175)

    K. Cornel, Meera P Mehta, B. Swift, A. Covens +3 more

    2023Gynecologic Oncology1 citations Open access

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47. EP390/#568 Apixaban for postoperative thromboprophylaxis as standard of care for gynecologic oncology patients: a real-world data study

    E. Spénard, W. Geerts, Yulia Lin, L. Gien +3 more

    2022E-Posters1 citations Open access

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48. Association of body mass index and length of stay in patients undergoing minimally invasive surgery for uterine cancer: a National Surgical Quality Improvement Program (NSQIP) study.

    A. Benseler, L. Gien, Brenna E. Swift, A. Covens +1 more

    2026International Journal of Gynecological Cancer0 citations Open access

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49. RATES OF REFERRAL TO GENETIC COUNSELLING AMONG PATIENTS WITH ENDOMETRIAL CANCER ELIGIBLE FOR GENETIC TESTING

    Olivia Polster, Karen Ott, L. Gien, Al Covens +5 more

    2026International Journal of Gynecological Cancer0 citations

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50. REPEAT SENTINEL LYMPH NODE BIOPSY IN RECURRENT VULVAR CANCER: IS THIS PROCEDURE RELIABLE?

    T.-T. Gao, Brenna E. Swift, D. Vicus, Al Covens +3 more

    2026International Journal of Gynecological Cancer0 citations

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