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A. Fortuño · SciRah

Researcher profile · Semantic Scholar

A. Fortuño

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A. Fortuño — researcher profile on SciRah

h-index: 38
Works: 93
Citations: 4,256

Most-cited papers

Oxidative Stress in Arterial Hypertension: Role of NAD(P)H Oxidase
G. Zalba, G. S. José, M. Moreno, M. Fortuño +3 more
2001HYPERTENSION454 citations Open access
Semantic Scholar
Vascular NADH/NADPH oxidase is involved in enhanced superoxide production in spontaneously hypertensive rats.
G. Zalba, F. J. Beaumont, G. S. José, A. Fortuño +3 more
2000HYPERTENSION392 citations Open access
Semantic Scholar
Role of NAD(P)H Oxidase
F. J. Beaumont, J. Dı́ez, G. Zalba, G. S. José +3 more
2001171 citations
Semantic Scholar
Oxidative stress and vascular remodelling
A. Fortuño, G. S. José, M. Moreno, J. Dı́ez +1 more
2005Experimental Physiology163 citations Open access
Semantic Scholar
Phagocytic NADPH oxidase overactivity underlies oxidative stress in metabolic syndrome.
A. Fortuño, Gorka San José, M. Moreno, O. Beloqui +2 more
2006Diabetes137 citations Open access
Semantic Scholar
The inhibitory effect of leptin on angiotensin II-induced vasoconstriction in vascular smooth muscle cells is mediated via a nitric oxide-dependent mechanism.
Amaia Rodríguez, A. Fortuño, J. Gómez-Ambrosi, G. Zalba +2 more
2007Endocrinology126 citations Open access
Semantic Scholar
Adipose tissue as an endocrine organ: role of leptin and adiponectin in the pathogenesis of cardiovascular diseases
A. Fortuño, Amaia Rodríguez, J. Gómez-Ambrosi, G. Frühbeck +1 more
2003Journal of physiology and biochemistry116 citations Open access
Semantic Scholar
Lysyl Oxidase Induces Vascular Oxidative Stress and Contributes to Arterial Stiffness and Abnormal Elastin Structure in Hypertension: Role of p38MAPK
Sonia Martínez-Revelles, A. García-Redondo, M. Avendaño, S. Varona +9 more
2017Antioxidants and Redox Signaling112 citations Open access
Semantic Scholar
Leptin inhibits angiotensin II-induced intracellular calcium increase and vasoconstriction in the rat aorta.
A. Fortuño, Amaia Rodríguez, J. Gómez-Ambrosi, P. Muñiz +3 more
2002Endocrinology111 citations Open access
Semantic Scholar
NADPH oxidase CYBA polymorphisms, oxidative stress and cardiovascular diseases.
Gorka San José, A. Fortuño, O. Beloqui, J. Dı́ez +1 more
2008Clinical science106 citations
Semantic Scholar
Cardiomyocyte Apoptotic Cell Death in Arterial Hypertension: Mechanisms and Potential Management
M. Fortuño, S. Ravassa, A. Fortuño, G. Zalba +1 more
2001HYPERTENSION105 citations Open access
Semantic Scholar
The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension
M. Moreno, G. S. José, A. Fortuño, O. Beloqui +2 more
2006Journal of Hypertension102 citations
Semantic Scholar
Association of increased phagocytic NADPH oxidase-dependent superoxide production with diminished nitric oxide generation in essential hypertension
A. Fortuño, S. Oliván, O. Beloqui, Gorka San José +3 more
2004Journal of Hypertension100 citations Open access
Semantic Scholar
NADPH Oxidase-Mediated Oxidative Stress: Genetic Studies of the p22phox Gene in Hypertension
G. Zalba, G. S. José, M. Moreno, A. Fortuño +1 more
2005Antioxidants and Redox Signaling91 citations
Semantic Scholar
Functional Effect of the p22phox −930A/G Polymorphism on p22phox Expression and NADPH Oxidase Activity in Hypertension
G. S. José, M. Moreno, S. Oliván, O. Beloqui +3 more
2004HYPERTENSION90 citations Open access
Semantic Scholar
Oxidative stress and atherosclerosis in early chronic kidney disease.
G. Zalba, A. Fortuño, J. Díez
2006Nephrology, Dialysis and Transplantation86 citations
Semantic Scholar
Increased CD74 expression in human atherosclerotic plaques: contribution to inflammatory responses in vascular cells.
J. Martín-Ventura, J. Madrigal-Matute, B. Muñóz-García, L. Blanco-Colio +8 more
2009Cardiovascular Research80 citations
Semantic Scholar
Oxidative Stress, Endothelial Dysfunction and Cerebrovascular Disease
G. Zalba, A. Fortuño, Gorka San José, M. Moreno +2 more
2007Cerebrovascular Diseases74 citations
Semantic Scholar
Vascular oxidant stress: Molecular mechanisms and pathophysiological implications
G. Zalba, J. Beaumont, G. S. José, A. Fortuño +2 more
2000Journal of physiology and biochemistry73 citations
Semantic Scholar
NADPH Oxidase—Dependent Superoxide Production Is Associated With Carotid Intima-Media Thickness in Subjects Free of Clinical Atherosclerotic Disease
G. Zalba, O. Beloqui, Gorka San José, M. Moreno +2 more
2005Arteriosclerosis, Thrombosis and Vascular Biology72 citations Open access
Semantic Scholar
Polymorphisms and Promoter Overactivity of the p22 phox Gene in Vascular Smooth Muscle Cells From Spontaneously Hypertensive Rats
G. Zalba, Gorka San José, F. J. Beaumont, M. Fortuño +2 more
2001Circulation Research66 citations Open access
Semantic Scholar
Losartan Metabolite EXP3179 Blocks NADPH Oxidase-Mediated Superoxide Production by Inhibiting Protein Kinase C: Potential Clinical Implications in Hypertension
A. Fortuño, J. Bidegain, Pablo A. Robador, J. Hermida +4 more
2009HYPERTENSION64 citations Open access
Semantic Scholar
Mechanisms of Increased Susceptibility to Angiotensin II–Induced Apoptosis in Ventricular Cardiomyocytes of Spontaneously Hypertensive Rats
S. Ravassa, M. Fortuño, Arantxa González, B. Lopez +3 more
2000HYPERTENSION64 citations Open access
Semantic Scholar
Is the balance between nitric oxide and superoxide altered in spontaneously hypertensive rats with endothelial dysfunction?
G. Zalba, F. J. Beaumont, Gorka San José, A. Fortuño +2 more
2001Nephrology, Dialysis and Transplantation63 citations Open access
Semantic Scholar
Sleep‐Disordered Breathing Is Independently Associated With Increased Aggressiveness of Cutaneous Melanoma: A Multicenter Observational Study in 443 Patients
M. Martínez-García, F. Campos-Rodriguez, E. Nagore, A. Martorell +78 more
2018Chest57 citations Open access
Semantic Scholar
Matrix Metalloproteinase-9 : Implications for Human Atherosclerosis Phagocytic NADPH Oxidase-Dependent Superoxide Production Stimulates
J. Rodríguez, O. Beloqui, J. Paramo, G. Zalba +4 more
200755 citations
Semantic Scholar
Mercury induces proliferation and reduces cell size in vascular smooth muscle cells through MAPK, oxidative stress and cyclooxygenase-2 pathways.
A. Aguado, M. Galán, Olha Zhenyukh, G. Wiggers +9 more
2013Toxicology and Applied Pharmacology54 citations
Semantic Scholar
Peroxisome proliferator-activated receptor-&ggr; activation reduces cyclooxygenase-2 expression in vascular smooth muscle cells from hypertensive rats by interfering with oxidative stress
Angela Martín, J. Pérez-Girón, R. Hernanz, R. Palacios +5 more
2012Journal of Hypertension54 citations
Semantic Scholar
Molecular Mechanisms of Atherosclerosis in Metabolic Syndrome: Role of Reduced IRS2-Dependent Signaling
H. González-Navarro, Á. Vinué, Marian Vila-Caballer, A. Fortuño +5 more
2008Arteriosclerosis, Thrombosis and Vascular Biology54 citations Open access
Semantic Scholar
Increased phagocytic nicotinamide adenine dinucleotide phosphate oxidase-dependent superoxide production in patients with early chronic kidney disease.
A. Fortuño, O. Beloqui, Gorka San José, M. Moreno +2 more
2005Kidney international. Supplement54 citations Open access
Semantic Scholar
HIF-1-mediated up-regulation of cardiotrophin-1 is involved in the survival response of cardiomyocytes to hypoxia.
Pablo A. Robador, Gorka San José, C. Rodríguez, Anna Guadall +6 more
2011Cardiovascular Research51 citations
Semantic Scholar
Leptin Induces Oxidative Stress Through Activation of NADPH Oxidase in Renal Tubular Cells: Antioxidant Effect of L‐Carnitine
A. J. Blanca, María V. Ruiz-Armenta, Sonia Zambrano, R. Salsoso +5 more
2016Journal of Cellular Biochemistry49 citations
Semantic Scholar
The inhibitory effect of leptin on angiotensin II-induced vasoconstriction is blunted in spontaneously hypertensive rats
Amaia Rodríguez, G. Frühbeck, J. Gómez-Ambrosi, V. Catalán +4 more
2006Journal of Hypertension45 citations
Semantic Scholar
Is leptin involved in phagocytic NADPH oxidase overactivity in obesity? Potential clinical implications
A. Fortuño, J. Bidegain, Ana Baltanás, M. Moreno +5 more
2010Journal of Hypertension44 citations
Semantic Scholar
A novel CYBA variant, the –675A/T polymorphism, is associated with essential hypertension
M. Moreno, G. S. José, A. Fortuño, O. Beloqui +5 more
2007Journal of Hypertension44 citations
Semantic Scholar
Leptin Inhibits the Proliferation of Vascular Smooth Muscle Cells Induced by Angiotensin II through Nitric Oxide-Dependent Mechanisms
Amaia Rodríguez, J. Gómez-Ambrosi, V. Catalán, A. Fortuño +1 more
2010Mediators of Inflammation43 citations Open access
Semantic Scholar
Torasemide inhibits angiotensin II-induced vasoconstriction and intracellular calcium increase in the aorta of spontaneously hypertensive rats.
A. Fortuño, P. Muñiz, S. Ravassa, J. Rodríguez +3 more
1999HYPERTENSION42 citations Open access
Semantic Scholar
Insulin-induced NADPH oxidase activation promotes proliferation and matrix metalloproteinase activation in monocytes/macrophages.
Gorka San José, J. Bidegain, Pablo A. Robador, J. Dı́ez +2 more
2009Free Radical Biology & Medicine40 citations
Semantic Scholar
Thioredoxin-1/peroxiredoxin-1 as sensors of oxidative stress mediated by NADPH oxidase activity in atherosclerosis.
J. Madrigal-Matute, C. Fernández-García, L. Blanco-Colio, E. Burillo +7 more
2015Free Radical Biology & Medicine38 citations
Semantic Scholar
Mechanisms underlying the cardiac antifibrotic effects of losartan metabolites
J. L. Miguel-Carrasco, J. Beaumont, Gorka San José, M. Moreno +6 more
2017Scientific Reports36 citations Open access
Semantic Scholar
Pharmacological evaluation of IQM‐95,333, a highly selective CCKA receptor antagonist with anxiolytic‐like activity in animal models
Santiago Ballaz, Ana Barber, A. Fortuño, J. Del Rı́o +5 more
1997British Journal of Pharmacology35 citations Open access
Semantic Scholar
p53-mediated upregulation of BAX gene transcription is not involved in Bax-alpha protein overexpression in the left ventricle of spontaneously hypertensive rats.
M. Fortuño, G. Zalba, S. Ravassa, Eva D'Elom +3 more
1999HYPERTENSION34 citations Open access
Semantic Scholar
Persistence of the Nitric Oxide Pathway in the Aorta of Hypercholesterolemic Apolipoprotein-E-Deficient Mice
N. Villeneuve, A. Fortuño, M. Sauvage, N. Fournier +7 more
2003Journal of Vascular Research29 citations
Semantic Scholar
Altered regulation of smooth muscle cell proliferation and apoptosis in small arteries of spontaneously hypertensive rats.
J. Dı́ez, M. Fortuño, G. Zalba, J. C. Etayo +3 more
1998European Heart Journal28 citations
Semantic Scholar
Synthesis and stereochemical structure-activity relationships of 1,3-dioxoperhydropyrido[1,2-c]pyrimidine derivatives: potent and selective cholecystokinin-A receptor antagonists.
M. Martín-Martínez, J. Bartolomé-Nebreda, I. Gomez-Monterrey, R. González-Muñiz +6 more
1997Journal of Medicinal Chemistry25 citations Open access
Semantic Scholar
Association of increased erythrocyte Na+/H+ exchanger with renal Na+ retention in patients with essential hypertension.
J. Dı́ez, Amalia Bernad Alonso, Ana Garciandia, Rafael López +3 more
1995American Journal of Hypertension25 citations
Semantic Scholar
NADPH Oxidase Overactivity Underlies Telomere Shortening in Human Atherosclerosis
Á. Pejenaute, Adriana Cortés, Javier Marqués, Laura Montero +5 more
2020International Journal of Molecular Sciences23 citations Open access
Semantic Scholar
The senescence-accelerated mouse prone-8 (SAM-P8) oxidative stress is associated with upregulation of renal NADPH oxidase system
Ana Baltanás, M. E. Solesio, G. Zalba, M. Galindo +2 more
2013Journal of physiology and biochemistry23 citations
Semantic Scholar
A Synthetic Peptide from Transforming Growth Factor-β1 Type III Receptor Inhibits NADPH Oxidase and Prevents Oxidative Stress in the Kidney of Spontaneously Hypertensive Rats
Ana Baltanás, J. L. Miguel-Carrasco, Gorka San José, C. Cebrián +8 more
2013Antioxidants and Redox Signaling23 citations
Semantic Scholar
Increased phagocytic NADPH oxidase activity associates with coronary artery calcification in asymptomatic men
O. Beloqui, M. Moreno, Gorka San José, Á. Pejenaute +5 more
2017Free radical research22 citations
Semantic Scholar

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G. Zalba×39
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J. Dı́ez×27
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M. Moreno×18
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O. Beloqui×16
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Gorka San José

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G. S. José×10

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