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N. Weygant · SciRah

Researcher profile · Semantic Scholar

N. Weygant

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N. Weygant — researcher profile on SciRah

h-index: 29
Works: 98
Citations: 2,061

Most-cited papers

DCLK1 Regulates Pluripotency and Angiogenic Factors via microRNA-Dependent Mechanisms in Pancreatic Cancer
Sripathi M. Sureban, Randal May, D. Qu, N. Weygant +7 more
2013PLoS ONE146 citations Open access
Semantic Scholar
XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism.
Sripathi M. Sureban, Randal May, N. Weygant, D. Qu +7 more
2014Cancer Letters119 citations
Semantic Scholar
Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1
N. Weygant, D. Qu, William L. Berry, Randal May +6 more
2014Molecular Cancer109 citations Open access
Semantic Scholar
DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma
N. Weygant, D. Qu, Randal May, R. Tierney +11 more
2014OncoTarget102 citations Open access
Semantic Scholar
Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells
P. Chandrakesan, Jian-Nan Yao, D. Qu, Randal May +11 more
2017Molecular Cancer101 citations Open access
Semantic Scholar
Dclk1 Deletion in Tuft Cells Results in Impaired Epithelial Repair After Radiation Injury
Randal May, D. Qu, N. Weygant, P. Chandrakesan +5 more
2014Stem Cells82 citations Open access
Semantic Scholar
Dclk1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition
P. Chandrakesan, N. Weygant, Randal May, D. Qu +6 more
2014OncoTarget81 citations Open access
Semantic Scholar
Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation
Ze-Yu Wang, Guanhua Su, Zi-Yu Dai, Ming Meng +9 more
2021Cell Proliferation76 citations Open access
Semantic Scholar
Cancer Stem Cell Marker DCLK1 Correlates with Tumorigenic Immune Infiltrates in the Colon and Gastric Adenocarcinoma Microenvironments
Xiang-Yan Wu, D. Qu, N. Weygant, Jun Peng +1 more
2020Cancers72 citations Open access
Semantic Scholar
Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer
Y. Ge, N. Weygant, D. Qu, Randal May +12 more
2018International Journal of Cancer69 citations Open access
Semantic Scholar
Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis
D. Qu, N. Weygant, Randal May, P. Chandrakesan +6 more
2015PLoS ONE66 citations Open access
Semantic Scholar
Identification of the putative intestinal stem cell marker DCAMKL-1 in Barrett’s Esophagus and Esophageal Adenocarcinoma
Kenneth J. Vega, Randal May, Sripathi M. Sureban, S. Lightfoot +10 more
2012Journal of Gastroenterology and Hepatology63 citations Open access
Semantic Scholar
Doublecortin-Like Kinase 1 Is Elevated Serologically in Pancreatic Ductal Adenocarcinoma and Widely Expressed on Circulating Tumor Cells
D. Qu, Jeremy J. Johnson, P. Chandrakesan, N. Weygant +17 more
2015PLoS ONE55 citations Open access
Semantic Scholar
Regulatory Roles of Dclk1 in Epithelial Mesenchymal Transition and Cancer Stem Cells
P. Chandrakesan, Janani Panneerselvam, D. Qu, N. Weygant +3 more
2016Journal of Carcinogenesis & Mutagenesis53 citations Open access
Semantic Scholar
Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism
Sripathi M. Sureban, Mohammad F. Madhoun, Randal May, D. Qu +7 more
2015OncoTarget51 citations Open access
Semantic Scholar
Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal
P. Chandrakesan, Randal May, D. Qu, N. Weygant +8 more
2015OncoTarget50 citations Open access
Semantic Scholar
A novel integrated system using patient-derived glioma cerebral organoids and xenografts for disease modeling and drug screening.
Li-Yang Zhang, Fang-Kun Liu, N. Weygant, Jun-Xia Zhang +15 more
2020Cancer Letters48 citations
Semantic Scholar
Intestinal tuft cells regulate the ATM mediated DNA Damage response via Dclk1 dependent mechanism for crypt restitution following radiation injury
P. Chandrakesan, Randal May, N. Weygant, D. Qu +7 more
2016Scientific Reports43 citations Open access
Semantic Scholar
DCLK1 Regulates Tumor Stemness and Cisplatin Resistance in Non-small Cell Lung Cancer via ABCD-Member-4
Janani Panneerselvam, Priyanga Mohandoss, Ravi B. Patel, Hamza Gillan +11 more
2020Molecular Therapy: Oncolytics42 citations Open access
Semantic Scholar
Tuft and Cancer Stem Cell Marker DCLK1: A New Target to Enhance Anti-Tumor Immunity in the Tumor Microenvironment
Zhi-Yun Cao, N. Weygant, P. Chandrakesan, C. Houchen +2 more
2020Cancers42 citations Open access
Semantic Scholar
Dietary Pectin Increases Intestinal Crypt Stem Cell Survival following Radiation Injury
Sripathi M. Sureban, Randal May, D. Qu, P. Chandrakesan +7 more
2015PLoS ONE41 citations Open access
Semantic Scholar
Inhibition of Notch signaling reduces the number of surviving Dclk1+ reserve crypt epithelial stem cells following radiation injury.
D. Qu, Randal May, Sripathi M. Sureban, N. Weygant +5 more
2014American Journal of Physiology - Gastrointestinal and Liver Physiology40 citations Open access
Semantic Scholar
Overexpression of DCLK1-AL Increases Tumor Cell Invasion, Drug Resistance, and KRAS Activation and Can Be Targeted to Inhibit Tumorigenesis in Pancreatic Cancer
D. Qu, N. Weygant, Jian-Nan Yao, P. Chandrakesan +11 more
2019Journal of Oncology37 citations Open access
Semantic Scholar
Applications of organoid technology to brain tumors
Jie Wen, Fang-Kun Liu, Q. Cheng, N. Weygant +5 more
2023CNS Neuroscience & Therapeutics35 citations Open access
Semantic Scholar
DCLK1-isoform2 alternative splice variant promotes pancreatic tumor immunosuppressive M2-macrophage polarization
P. Chandrakesan, Janani Panneerselvam, Randal May, N. Weygant +7 more
2020Molecular Cancer Therapeutics34 citations Open access
Semantic Scholar
The role of sex in the innate and adaptive immune environment of metastatic colorectal cancer
A. Ray, R. Nofchissey, M. Khan, M. Reidy +10 more
2020British Journal of Cancer33 citations Open access
Semantic Scholar
Fluvastatin Interferes with Hepatitis C Virus Replication via Microtubule Bundling and a Doublecortin-like Kinase-Mediated Mechanism
N. Ali, Heba Allam, T. Bader, Randal May +11 more
2013PLoS ONE32 citations Open access
Semantic Scholar
Survival of patients with gastrointestinal cancers can be predicted by a surrogate microRNA signature for cancer stem-like cells marked by DCLK1 kinase
N. Weygant, Y. Ge, D. Qu, John S. Kaddis +9 more
2016Cancer Research31 citations Open access
Semantic Scholar
(Z)-3,5,4'-Trimethoxystilbene Limits Hepatitis C and Cancer Pathophysiology by Blocking Microtubule Dynamics and Cell Cycle Progression
Charles B. Nguyen, H. Kotturi, G. Waris, A. Mohammed +10 more
2016Cancer Research30 citations Open access
Semantic Scholar
RAS/BRAF Circulating Tumor DNA Mutations as a Predictor of Response to First-Line Chemotherapy in Metastatic Colorectal Cancer Patients
Jian-Nan Yao, Wanchun Zang, Y. Ge, N. Weygant +10 more
2018Canadian Journal of Gastroenterology and Hepatology29 citations Open access
Semantic Scholar
Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases
N. Ali, P. Chandrakesan, Charles B. Nguyen, S. Husain +10 more
2015OncoTarget28 citations Open access
Semantic Scholar
Huoxin pill attenuates myocardial infarction-induced apoptosis and fibrosis via suppression of p53 and TGF-β1/Smad2/3 pathways.
Zhi-Qing Shen, Aling Shen, Xiaoping Chen, Xiang-Yan Wu +9 more
2020Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie27 citations Open access
Semantic Scholar
Inhibition of DCLK1 with DCLK1-IN-1 Suppresses Renal Cell Carcinoma Invasion and Stemness and Promotes Cytotoxic T-Cell-Mediated Anti-Tumor Immunity
Ling Ding, Yu-Ning Yang, Y. Ge, Q. Lu +9 more
2021Cancers24 citations Open access
Semantic Scholar
Bufalin Inhibits Tumorigenesis, Stemness, and Epithelial–Mesenchymal Transition in Colorectal Cancer through a C-Kit/Slug Signaling Axis
Ling Ding, Yu-Ning Yang, Q. Lu, D. Qu +8 more
2022International Journal of Molecular Sciences21 citations Open access
Semantic Scholar
DCLK1-Short Splice Variant Promotes Esophageal Squamous Cell Carcinoma Progression via the MAPK/ERK/MMP2 Pathway
Y. Ge, Xiao-Na Fan, Xu-Ying Huang, N. Weygant +6 more
2021Molecular Cancer Research18 citations Open access
Semantic Scholar
Qingda granule exerts neuroprotective effects against ischemia/reperfusion-induced cerebral injury via lncRNA GAS5/miR-137 signaling pathway
Ling Zhang, Q. Cai, Shan Lin, Bin Chen +5 more
2021International Journal of Medical Sciences17 citations Open access
Semantic Scholar
Role of DCLK1 in oncogenic signaling (Review).
Qin Lu, Hailan Feng, H. Chen, N. Weygant +3 more
2022International Journal of Oncology16 citations Open access
Semantic Scholar
Differential risks of immune-related colitis among various immune checkpoint inhibitor regimens.
Jian-Nan Yao, Man-Yu Li, Hui-Yun Zhang, Y. Ge +2 more
2020International Immunopharmacology15 citations
Semantic Scholar
Ribosome assembly factor PNO1 is associated with progression and promotes tumorigenesis in triple-negative breast cancer
Jie Li, Li-Ya Liu, Youqin Chen, Mei-Zhu Wu +12 more
2022Oncology Report11 citations Open access
Semantic Scholar
Correction: Fluvastatin Interferes with Hepatitis C Virus Replication via Microtubule Bundling and a Doublecortin-like Kinase-Mediated Mechanism
N. Ali, Heba Allam, T. Bader, Randal May +11 more
2013PLoS ONE10 citations Open access
Semantic Scholar
Tuft cells: an emerging therapeutic target for pancreatitis and pancreatic cancer?
Yu-Ning Yang, Ling Ding, Zhi-Yun Cao, D. Qu +1 more
2020Expert opinion on therapeutic targets8 citations Open access
Semantic Scholar
Differential Dermatologic Adverse Events Associated With Checkpoint Inhibitor Monotherapy and Combination Therapy: A Meta-Analysis of Randomized Control Trials
Y. Ge, Hui-Yun Zhang, N. Weygant, Jian-Nan Yao
2021Frontiers in Pharmacology7 citations Open access
Semantic Scholar
Sex-Associated Gene Expression Alterations Correlate With Esophageal Cancer Survival
N. Weygant, K. Chang, C. Jackson, K. Vega
2020Clinical and Translational Gastroenterology7 citations Open access
Semantic Scholar
DCLK1 and Tuft Cells: Immune-Related Functions and Implications for Cancer Immunotherapy.
Ling Ding, N. Weygant, Chenhuan Ding, Yi Lai +1 more
2023Critical reviews in oncology/hematology5 citations Open access
Semantic Scholar
Establishment of a Competing Risk Nomogram in Patients with Pulmonary Sarcomatoid Carcinoma
Zi-Wei Liang, En-Yu Zhang, L. Duan, N. Weygant +3 more
2022Technology in Cancer Research and Treatment5 citations Open access
Semantic Scholar
Role of the Microenvironment in Gastrointestinal Tumors
N. Weygant, Y. Ge, C. B. Westphalen, Wen W. Ma +1 more
2019Journal of Oncology5 citations Open access
Semantic Scholar
Emerging Prospects for the Study of Colorectal Cancer Stem Cells using Patient-Derived Organoids.
Ling Ding, Yu-Ning Yang, Qin Lu, Zhi-Yun Cao +1 more
2022Current Cancer Drug Targets4 citations
Semantic Scholar
Implications for Tumor Microenvironment and Epithelial Crosstalk in the Management of Gastrointestinal Cancers
Y. Ge, C. B. Westphalen, Wen W. Ma, K. Vega +1 more
2019Journal of Oncology4 citations Open access
Semantic Scholar
Elevated doublecortin-like kinase 1 serum levels revert to baseline after therapy in early stage esophageal adenocarcinoma
Emily M. Christman, P. Chandrakesan, N. Weygant, J. Maple +3 more
2019Biomarker Research4 citations Open access
Semantic Scholar
Palmdelphin facilitates R-spondin2 secretion to activate Wnt signaling and promote colorectal cancer stemness and tumorigenesis
Yu-Ning Yang, Jinsen Shi, Yu-Ping Yang, Sihan Liu +18 more
2025bioRxiv2 citations
Semantic Scholar

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D. Qu — researcher profile on SciRah
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Sripathi M. Sureban

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