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L. Sharples · SciRah

Researcher profile · Semantic Scholar

L. Sharples

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L. Sharples — researcher profile on SciRah

h-index: 62
Works: 287
Citations: 15K

Most-cited papers

Randomized Controlled Trial of Rituximab and Cost‐Effectiveness Analysis in Treating Fatigue and Oral Dryness in Primary Sjögren's Syndrome
S. Bowman, C. Everett, J. O'Dwyer, P. Emery +19 more
2017Arthritis & Rheumatology289 citations Open access
Semantic Scholar
Effect of Care Guided by Cardiovascular Magnetic Resonance, Myocardial Perfusion Scintigraphy, or NICE Guidelines on Subsequent Unnecessary Angiography Rates: The CE-MARC 2 Randomized Clinical Trial.
J. Greenwood, D. Ripley, C. Berry, G. Mccann +13 more
2016Journal of the American Medical Association (JAMA)284 citations Open access
Semantic Scholar
Meta-analysis of randomised controlled trials of oral mandibular advancement devices and continuous positive airway pressure for obstructive sleep apnoea-hypopnoea
L. Sharples, A. Clutterbuck-James, M. Glover, Maxine Bennett +3 more
2015Sleep Medicine Reviews187 citations Open access
Semantic Scholar
A systematic review and meta‐analysis estimating the population prevalence of comorbidities in children and adolescents aged 5 to 18 years
V. Sharma, S. Coleman, J. Nixon, L. Sharples +3 more
2019Obesity Reviews147 citations Open access
Semantic Scholar
Regression discontinuity designs: an approach to the evaluation of treatment efficacy in primary care using observational data
Aidan G. O'Keeffe, S. Geneletti, G. Baio, L. Sharples +2 more
2014British medical journal135 citations Open access
Semantic Scholar
Effect of rituximab on a salivary gland ultrasound score in primary Sjögren’s syndrome: results of the TRACTISS randomised double-blind multicentre substudy
B. Fisher, C. Everett, J. Rout, J. O'Dwyer +23 more
2017Annals of the Rheumatic Diseases120 citations Open access
Semantic Scholar
Extrapolating Survival from Randomized Trials Using External Data: A Review of Methods
C. Jackson, John W. Stevens, Shi-Jie Ren, N. Latimer +3 more
2016Medical decision making117 citations Open access
Semantic Scholar
Nonproportional Hazards for Time-to-Event Outcomes in Clinical Trials: JACC Review Topic of the Week.
J. Gregson, L. Sharples, G. Stone, C. Burman +2 more
2019Journal of the American College of Cardiology100 citations Open access
Semantic Scholar
A crossover randomised controlled trial of oral mandibular advancement devices for obstructive sleep apnoea-hypopnoea (TOMADO)
T. Quinnell, Maxine Bennett, Jake Jordan, A. Clutterbuck-James +10 more
2014Thorax87 citations Open access
Semantic Scholar
Impact of donor mismatches at individual HLA-A, -B, -C, -DR, and -DQ loci on the development of HLA-specific antibodies in patients listed for repeat renal transplantation.
V. Kosmoliaptsis, O. Gjorgjimajkoska, L. Sharples, A. Chaudhry +6 more
2014Kidney International77 citations Open access
Semantic Scholar
The contribution of the anaesthetist to risk‐adjusted mortality after cardiac surgery
O. Papachristofi, L. Sharples, J. Mackay, S. Nashef +11 more
2015Anaesthesia71 citations Open access
Semantic Scholar
Multi-State modelling of repeated hospitalisation and death in patients with Heart Failure: the use of large administrative databases in clinical epidemiology
F. Ieva, C. Jackson, L. Sharples
2015Statistical Methods in Medical Research70 citations Open access
Semantic Scholar
Sex-related differences in left ventricular remodeling in severe aortic stenosis and reverse remodeling after aortic valve replacement: A cardiovascular magnetic resonance study.
L. Dobson, T. Fairbairn, T. Musa, A. Uddin +11 more
2016American Heart Journal66 citations Open access
Semantic Scholar
Interventions in randomised controlled trials in surgery: issues to consider during trial design
N. Blencowe, Julia M. Brown, J. Cook, C. Metcalfe +5 more
2015Trials64 citations Open access
Semantic Scholar
Cost-effectiveness of initial stress cardiovascular MR, stress SPECT or stress echocardiography as a gate-keeper test, compared with upfront invasive coronary angiography in the investigation and management of patients with stable chest pain: mid-term outcomes from the CECaT randomised controlled tr
H. Thom, N. West, V. Hughes, M. Dyer +4 more
2014BMJ Open62 citations Open access
Semantic Scholar
Assessment of learning curves in complex surgical interventions: a consecutive case-series study
O. Papachristofi, D. Jenkins, L. Sharples
2016Trials59 citations Open access
Semantic Scholar
Right Ventricular Reverse Remodeling after Pulmonary Endarterectomy: Magnetic Resonance Imaging and Clinical and Right Heart Catheterization Assessment
M. Berman, D. Gopalan, L. Sharples, N. Screaton +6 more
2014Pulmonary Circulation58 citations Open access
Semantic Scholar
Clinical effectiveness and cost-effectiveness results from the randomised controlled Trial of Oral Mandibular Advancement Devices for Obstructive sleep apnoea-hypopnoea (TOMADO) and long-term economic analysis of oral devices and continuous positive airway pressure.
L. Sharples, M. Glover, A. Clutterbuck-James, Maxine Bennett +11 more
2014Health Technology Assessment54 citations Open access
Semantic Scholar
Mini‐Stern Trial: A randomized trial comparing mini‐sternotomy to full median sternotomy for aortic valve replacement
S. Nair, C. Sudarshan, Benjamin Thorpe, Jeshika Singh +11 more
2018Journal of Thoracic and Cardiovascular Surgery52 citations Open access
Semantic Scholar
The relationship between three-dimensional knee MRI bone shape and total knee replacement—a case control study: data from the Osteoarthritis Initiative
A. Barr, B. Dube, E. Hensor, S. Kingsbury +4 more
2016Rheumatology48 citations Open access
Semantic Scholar
Experiences of Structured Elicitation for Model-Based Cost-Effectiveness Analyses
M. Soares, L. Sharples, Alec Morton, K. Claxton +1 more
2018Value in Health44 citations Open access
Semantic Scholar
Impact of the anesthesiologist and surgeon on cardiac surgical outcomes.
O. Papachristofi, J. Mackay, S. Powell, S. Nashef +1 more
2014Journal of Cardiothoracic and Vascular Anesthesia41 citations Open access
Semantic Scholar
Survival extrapolation using the poly-Weibull model
Nikolaos Demiris, D. Lunn, L. Sharples
2015Statistical Methods in Medical Research40 citations Open access
Semantic Scholar
Bayesian regression discontinuity designs: incorporating clinical knowledge in the causal analysis of primary care data
S. Geneletti, Aidan G. O'Keeffe, L. Sharples, S. Richardson +1 more
2014Statistics in Medicine40 citations Open access
Semantic Scholar
Evaluation of the impact of the GRACE risk score on the management and outcome of patients hospitalised with non-ST elevation acute coronary syndrome in the UK: protocol of the UKGRIS cluster-randomised registry-based trial
C. Everett, K. Fox, C. Reynolds, C. Fernandez +9 more
2019BMJ Open36 citations Open access
Semantic Scholar
Alternative tumour necrosis factor inhibitors (TNFi) or abatacept or rituximab following failure of initial TNFi in rheumatoid arthritis: the SWITCH RCT.
Sarah R. Brown, C. Everett, K. Naraghi, C. Davies +7 more
2018Health Technology Assessment35 citations Open access
Semantic Scholar
Logistic regression and machine learning predicted patient mortality from large sets of diagnosis codes comparably.
T. Cowling, D. Cromwell, A. Bellot, L. Sharples +1 more
2020Journal of Clinical Epidemiology34 citations Open access
Semantic Scholar
Reference Case Methods for Expert Elicitation in Health Care Decision Making
L. Bojke, M. Soares, K. Claxton, A. Colson +6 more
2021Medical decision making33 citations Open access
Semantic Scholar
Effect of individual patient risk, centre, surgeon and anaesthetist on length of stay in hospital after cardiac surgery: Association of Cardiothoracic Anaesthesia and Critical Care (ACTACC) consecutive cases series study of 10 UK specialist centres
O. Papachristofi, A. Klein, J. Mackay, S. Nashef +2 more
2017BMJ Open31 citations Open access
Semantic Scholar
Effectiveness of GRACE risk score in patients admitted to hospital with non-ST elevation acute coronary syndrome (UKGRIS): parallel group cluster randomised controlled trial
C. Gale, D. Stocken, S. Aktaa, C. Reynolds +9 more
2023British medical journal29 citations Open access
Semantic Scholar
Nonparametric frailty Cox models for hierarchical time-to-event data
Francesca Gasperoni, F. Ieva, A. Paganoni, C. Jackson +1 more
2018Biostatistics27 citations Open access
Semantic Scholar
Use of a Structured Mirrors Intervention Does Not Reduce Delirium Incidence But May Improve Factual Memory Encoding in Cardiac Surgical ICU Patients Aged Over 70 Years: A Pilot Time-Cluster Randomized Controlled Trial
K. Giraud, M. Pontin, L. Sharples, P. Fletcher +4 more
2016Frontiers in Aging Neuroscience27 citations Open access
Semantic Scholar
Probabilistic linkage without personal information successfully linked national clinical datasets
H. Blake, L. Sharples, K. Harron, J. H. van der Meulen +1 more
2021Journal of Clinical Epidemiology20 citations Open access
Semantic Scholar
Identifying the research priorities of healthcare professionals in UK vascular surgery: modified Delphi approach
G. Smith, J. Long, T. Wallace, D. Carradice +26 more
2020BJS Open20 citations Open access
Semantic Scholar
Amaze: a randomized controlled trial of adjunct surgery for atrial fibrillation
S. Nashef, S. Fynn, Y. Abu-Omar, T. Spyt +10 more
2018European Journal of Cardio-Thoracic Surgery19 citations Open access
Semantic Scholar
The INVEST project: investigating the use of evidence synthesis in the design and analysis of clinical trials
G. Clayton, I. Smith, J. Higgins, B. Mihaylova +8 more
2017Trials18 citations Open access
Semantic Scholar
Amaze: a double-blind, multicentre randomised controlled trial to investigate the clinical effectiveness and cost-effectiveness of adding an ablation device-based maze procedure as an adjunct to routine cardiac surgery for patients with pre-existing atrial fibrillation.
L. Sharples, C. Everett, Jeshika Singh, Christine Mills +8 more
2018Health Technology Assessment16 citations Open access
Semantic Scholar
Faecal immunochemical testing in bowel cancer screening: Estimating outcomes for different diagnostic policies
Shuping J. Li, L. Sharples, S. Benton, Oleg Blyuss +3 more
2020Journal of Medical Screening15 citations Open access
Semantic Scholar
Multiple Interventions for Diabetic Foot Ulcer Treatment Trial (MIDFUT): study protocol for a randomised controlled trial
Sarah R. Brown, J. Nixon, M. Ransom, R. Gilberts +18 more
2020BMJ Open13 citations Open access
Semantic Scholar
State selection in Markov models for panel data with application to psoriatic arthritis
H. Thom, C. Jackson, D. Commenges, L. Sharples
2015Statistics in Medicine12 citations Open access
Semantic Scholar
Systematic review of endovascular stent grafting versus open surgical repair for the elective treatment of arch/descending thoracic aortic aneurysms
A. McCarthy, Jo Gray, P. Sastry, L. Sharples +6 more
2021BMJ Open11 citations Open access
Semantic Scholar
Impact of changes to the interscreening interval and faecal immunochemical test threshold in the national bowel cancer screening programme in England: results from the FIT pilot study
Shuping J. Li, Tara Seedher, L. Sharples, S. Benton +4 more
2022British Journal of Cancer10 citations Open access
Semantic Scholar
Evaluation of the effects of multiple providers in complex surgical interventions
O. Papachristofi, A. Klein, L. Sharples
2016Statistics in Medicine10 citations
Semantic Scholar
Exploring mechanisms of action in clinical trials of complex surgical interventions using mediation analysis
L. Sharples, O. Papachristofi, Saleema Rex, S. Landau
2020Clinical Trials9 citations Open access
Semantic Scholar
Developing a reference protocol for expert elicitation in healthcare decision making
L. Bojke, M. Soares, A. Fox, D. Janković +6 more
20199 citations
Semantic Scholar
Does the "Weekend Effect" for Postoperative Mortality Stand Up to Scrutiny? Association for Cardiothoracic Anesthesia and Critical Care Cohort Study of 110,728 Cardiac Surgical Patients.
O. Papachristofi, A. Klein, J. Mackay, S. Nashef +2 more
2018Journal of Cardiothoracic and Vascular Anesthesia9 citations Open access
Semantic Scholar
Methods of analysis for survival outcomes with time-updated mediators, with application to longitudinal disease registry data
K. Tanner, L. Sharples, R. Daniel, R. Keogh
2022Statistical Methods in Medical Research8 citations Open access
Semantic Scholar
Including random centre effects in design, analysis and presentation of multi-centre trials
K. Edgar, I. Roberts, L. Sharples
2021Trials8 citations Open access
Semantic Scholar
Response to comments on "Meta-analysis of randomised controlled trials of oral mandibular advancement devices and continuous positive airway pressure for obstructive sleep apnoea-hypopnoea".
L. Sharples, T. Quinnell
2016Sleep Medicine Reviews8 citations
Semantic Scholar
A novel approach selected small sets of diagnosis codes with high prediction performance in large healthcare datasets.
T. Cowling, D. Cromwell, L. Sharples, J. H. van der Meulen
2020Journal of Clinical Epidemiology7 citations Open access
Semantic Scholar

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