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N. Naoumov · SciRah

Researcher profile · Semantic Scholar

N. Naoumov

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N. Naoumov — researcher profile on SciRah

h-index: 55
Works: 227
Citations: 11K

Most-cited papers

Telbivudine versus lamivudine in patients with chronic hepatitis B.
Ching-Lung Lai, E. Gane, Y. Liaw, Chao-Wei Hsu +14 more
2007New England Journal of Medicine362 citations Open access
Semantic Scholar
Report of an international workshop: Roadmap for management of patients receiving oral therapy for chronic hepatitis B.
E. Keeffe, S. Zeuzem, R. Koff, D. Dieterich +8 more
2007Clinical Gastroenterology and Hepatology273 citations Open access
Semantic Scholar
CD8+ T Cell Control of Hepatitis B Virus Replication: Direct Comparison between Cytolytic and Noncytolytic Functions
S. Phillips, S. Chokshi, A. Riva, A. Evans +2 more
2009Journal of Immunology228 citations
Semantic Scholar
Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen–positive patients
K. Wursthorn, M. Jung, A. Riva, Z. Goodman +5 more
2010Hepatology220 citations Open access
Semantic Scholar
Baseline characteristics and early on-treatment response predict the outcomes of 2 years of telbivudine treatment of chronic hepatitis B.
S. Zeuzem, E. Gane, Y. Liaw, Seng G. Lim +12 more
2009Journal of Hepatology204 citations
Semantic Scholar
Tropifexor for nonalcoholic steatohepatitis: an adaptive, randomized, placebo-controlled phase 2a/b trial
A. Sanyal, P. López, E. Lawitz, K. Lucas +23 more
2023Nature Medicine167 citations Open access
Semantic Scholar
Programmed death 1 expression during antiviral treatment of chronic hepatitis B: Impact of hepatitis B e‐antigen seroconversion
A. Evans, A. Riva, H. Cooksley, S. Phillips +5 more
2008Hepatology147 citations Open access
Semantic Scholar
Cyclophilin inhibition as potential therapy for liver diseases.
N. Naoumov
2014Journal of Hepatology107 citations Open access
Semantic Scholar
Digital pathology with artificial intelligence analyses provides greater insights into treatment-induced fibrosis regression in NASH.
N. Naoumov, D. Brees, Juergen Loeffler, Elaine L K Chng +5 more
2022Journal of Hepatology105 citations Open access
Semantic Scholar
High serum IL-21 levels after 12 weeks of antiviral therapy predict HBeAg seroconversion in chronic hepatitis B.
Shi-Wu Ma, Xuan Huang, Yong-Yin Li, Li-Bo Tang +9 more
2012Journal of Hepatology104 citations
Semantic Scholar
Circulating chemokine (C‐X‐C Motif) receptor 5+CD4+ T cells benefit hepatitis B e antigen seroconversion through IL‐21 in patients with chronic hepatitis B virus infection
Yong-Yin Li, Shi-Wu Ma, Li-Bo Tang, Yun Li +10 more
2013Hepatology90 citations
Semantic Scholar
Novel Mechanism of Antibodies to Hepatitis B Virus in Blocking Viral Particle Release from Cells
A. Neumann, S. Phillips, Idit Levine, S. Ijaz +4 more
2010Hepatology78 citations Open access
Semantic Scholar
Telbivudine plus pegylated interferon alfa-2a in a randomized study in chronic hepatitis B is associated with an unexpected high rate of peripheral neuropathy.
P. Marcellin, K. Wursthorn, H. Wedemeyer, Wan-Long Chuang +13 more
2015Journal of Hepatology61 citations
Semantic Scholar
Tropifexor plus cenicriviroc combination versus monotherapy in nonalcoholic steatohepatitis: Results from the phase 2b TANDEM study
Q. Anstee, K. Lucas, S. Francque, M. Abdelmalek +22 more
2023Hepatology59 citations Open access
Semantic Scholar
Alisporivir Inhibition of Hepatocyte Cyclophilins Reduces HBV Replication and Hepatitis B Surface Antigen Production
S. Phillips, S. Chokshi, U. Chatterji, A. Riva +4 more
2014Gastroenterology58 citations Open access
Semantic Scholar
Hepatitis C virus (HCV)--specific T cell responses in injection drug users with apparent resistance to HCV infection.
P. Thurairajah, D. Hegazy, S. Chokshi, Steve Shaw +4 more
2008Journal of Infectious Diseases58 citations
Semantic Scholar
Molecular epidemiology and interferon susceptibility of the natural recombinant hepatitis C virus strain RF1_2k/1b.
F. Kurbanov, Yasuhito Tanaka, E. Chub, I. Maruyama +12 more
2008Journal of Infectious Diseases55 citations
Semantic Scholar
Hepatitis B Virus e Antigen Loss during Adefovir Dipivoxil Therapy Is Associated with Enhanced Virus-Specific CD4+ T-Cell Reactivity
H. Cooksley, S. Chokshi, Yafit Maayan, H. Wedemeyer +9 more
2007Antimicrobial Agents and Chemotherapy54 citations Open access
Semantic Scholar
Truncated CXCL10 is associated with failure to achieve spontaneous clearance of acute hepatitis C infection
A. Riva, M. Laird, A. Casrouge, A. Ambrozaitis +4 more
2014Hepatology50 citations Open access
Semantic Scholar
Alisporivir plus ribavirin, interferon free or in combination with pegylated interferon, for hepatitis C virus genotype 2 or 3 infection
J. Pawlotsky, R. Flisiak, S. Sarin, J. Rasenack +12 more
2015Hepatology48 citations Open access
Semantic Scholar
Immunological techniques in viral hepatitis.
B. Rehermann, N. Naoumov
2007Journal of Hepatology47 citations
Semantic Scholar
Dynamics of lamivudine‐resistant hepatitis B virus during adefovir monotherapy versus lamivudine plus adefovir combination therapy
S. Ijaz, C. Arnold, S. Dervisevic, Jana Měchurová +3 more
2008Journal of Medical Virology46 citations
Semantic Scholar
Genetic characteristics of hepatitis B virus genotypes as a factor for interferon‐induced HBeAg clearance
Jin-Lin Hou, R. Schilling, H. Janssen, B. Hansen +6 more
2007Journal of Medical Virology44 citations
Semantic Scholar
The Combination of Alisporivir plus an NS5A Inhibitor Provides Additive to Synergistic Anti-Hepatitis C Virus Activity without Detectable Cross-Resistance
U. Chatterji, Jose A. Garcia-Rivera, James M Baugh, K. Gawlik +5 more
2014Antimicrobial Agents and Chemotherapy43 citations Open access
Semantic Scholar
1405 ALISPORIVIR PLUS RIBAVIRIN IS HIGHLY EFFECTIVE AS INTERFERON-FREE OR INTERFERON-ADD-ON REGIMEN IN PREVIOUSLY UNTREATED HCV-GT2 OR GT3 PATIENTS: SVR12 RESULTS FROM VITAL-1 PHASE 2B STUDY
J. Pawlotsky, S. Sarin, G. Foster, C. Peng +7 more
201243 citations
Semantic Scholar
Impact of Early Viral Kinetics on T-Cell Reactivity during Antiviral Therapy in Chronic Hepatitis B
G. Lau, H. Cooksley, R. Ribeiro, K. Powers +11 more
2007Antiviral Therapy43 citations
Semantic Scholar
Randomised clinical trial: alisporivir combined with peginterferon and ribavirin in treatment‐naïve patients with chronic HCV genotype 1 infection (ESSENTIAL II)
S. Zeuzem, R. Flisiak, J. Vierling, W. Mazur +19 more
2015Alimentary Pharmacology and Therapeutics40 citations Open access
Semantic Scholar
The diversity and management of chronic hepatitis B virus infections in the United Kingdom: a wake-up call.
R. Tedder, A. Rodger, L. Fries, S. Ijaz +23 more
2012Clinical Infectious Diseases40 citations Open access
Semantic Scholar
Distribution and characteristics of hepatitis B virus genotype C subgenotypes in China *
Z. Wang, J. Hou, G. Zeng, S. Wen +8 more
2007Journal of Viral Hepatitis37 citations
Semantic Scholar
Chronic hepatitis B: a critical appraisal of current approaches to therapy.
R. Perrillo, R. Gish, M. Peters, E. Keeffe +11 more
2006Clinical Gastroenterology and Hepatology33 citations Open access
Semantic Scholar
13 TELBIVUDINE (LDT) PLUS PEG-INTERFERON (PEGIFN) IN HBEAG-POSITIVE CHRONIC HEPATITIS B – VERY POTENT ANTIVIRAL EFFICACY BUT RISK OF PERIPHERAL NEUROPATHY (PN)
P. Marcellin, C. Avila, Karsten Wursthorn, Wan-Lung Chuang +6 more
201028 citations Open access
Semantic Scholar
Modeling viral kinetics and treatment outcome during alisporivir interferon‐free treatment in hepatitis C virus genotype 2 and 3 patients
J. Guedj, Jing Yu, M. Levi, Bin Li +3 more
2014Hepatology27 citations Open access
Semantic Scholar
High accuracy model for HBsAg loss based on longitudinal trajectories of serum qHBsAg throughout long-term antiviral therapy
Rong Fan, Si-Ru Zhao, Jun-Qi Niu, Hong Ma +18 more
2024Gut26 citations Open access
Semantic Scholar
Protection of Hepatocytes from Cytotoxic T Cell Mediated Killing by Interferon-Alpha
C. Willberg, S. Ward, R. Clayton, N. Naoumov +5 more
2007PLoS ONE26 citations Open access
Semantic Scholar
Direct evidence for immunomodulatory properties of ribavirin on T-cell reactivity to hepatitis C virus.
E. Rigopoulou, W. Abbott, Roger Williams, N. Naoumov
2007Antiviral Research26 citations
Semantic Scholar
Long-Term Telbivudine Treatment Results in Resolution of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis B
Jin-Lin Hou, Dao-zhen Xu, Guang-Feng Shi, M. Wan +14 more
2015Advances in Therapy24 citations Open access
Semantic Scholar
APOBEC and iNOS are not the main intracellular effectors of IFN-gamma-mediated inactivation of Hepatitis B virus replication.
S. Proto, John A. Taylor, S. Chokshi, N. Navaratnam +1 more
2008Antiviral Research20 citations
Semantic Scholar
Impact of NS5A sequences of Hepatitis C virus genotype 1a on early viral kinetics during treatment with peginterferon- alpha 2a plus ribavirin.
F. dal Pero, Kwok H. Tang, M. Gerotto, G. Bortoletto +5 more
2007Journal of Infectious Diseases19 citations
Semantic Scholar
706 SUSTAINED DURABILITY OF HBEAG SEROCONVERSION IN CHRONIC HEPATITIS B PATIENTS AFTER TREATMENT WITH TELBIVUDINE
T. Poynard, Jin-Lin Hou, A. Chutaputti, M. Manns +1 more
200818 citations Open access
Semantic Scholar
Viral clearance or persistence after acute hepatitis C infection: interim results from a prospective study.
A. Guobužaitė, S. Chokshi, L. Balčiūnienė, Alina Voinic +4 more
2008Medicina17 citations Open access
Semantic Scholar
Identification of Serum Cytokine Profiles Associated with HBeAg Seroconversion Following Antiviral Treatment Interruption
S. Chokshi, H. Cooksley, A. Riva, S. Phillips +3 more
2014Viral immunology16 citations Open access
Semantic Scholar
Early viraemia clearance during antiviral therapy of chronic hepatitis C improves dendritic cell functions.
I. Pachiadakis, S. Chokshi, H. Cooksley, D. Farmakiotis +4 more
2009Clinical Immunology16 citations
Semantic Scholar
Presence of hepatitis B virus core promoter mutations pre-seroconversion predict persistent viral replication after HBeAg loss.
R. Ferns, N. Naoumov, R. Gilson, R. Tedder
2007Journal of Clinical Virology16 citations
Semantic Scholar
17 KINETICS OF HBsAg DECLINE IN HBeAg+ CHRONIC HEPATITIS B PATIENTS WITH 3 YEARS OF TELBIVUDINE TREATMENT DURING THE GLOBE STUDY
K. Wursthorn, M. Jung, M. Manns, P. López +2 more
200915 citations
Semantic Scholar
An Engineered Non-Toxic Superantigen Increases Cross Presentation of Hepatitis B Virus Nucleocapsids by Human Dendritic Cells
Julie D. McIntosh, Kristy Manning, S. Chokshi, N. Naoumov +3 more
2014PLoS ONE14 citations Open access
Semantic Scholar
821 INTERFERON (IFN)-FREE ALISPORIVIR (ALV) HAS A BETTER OVERALL SAFETY PROFILE COMPARED TO IFN-CONTAINING TREATMENT: A POOLED ANALYSIS OF THE ALV DEVELOPMENT PROGRAM
L. Griffel, W. Bao, R. Orsenigo, V. Guo +5 more
201313 citations
Semantic Scholar
Il-1beta Signal Inhibition in acute alcoholic hepatitis: a multicentre, randomised, double-blind, placebo-controlled phase 2 trial of canakinumab therapy (ISAIAH)
N. Vergis, V. Patel, K. Bogdanowicz, J. Czyzewska-Khan +23 more
2022Journal of Hepatology10 citations
Semantic Scholar
ALISPORIVIR - A HOST-TARGETING ANTIVIRAL, PROVIDES LOW VIRAL BREAKTHROUGH RATE AND HIGH BARRIER TO RESISTANCE IN HCV GENOTYPE 1 TREATMENT-NAiVE PATIENTS IN THE PHASE IIB ESSENTIAL STUDY
Bing Li, J. Snoeck, Yanhua Tang, Christopher T. Jones +9 more
201110 citations
Semantic Scholar
Early Viral Kinetics with Telbivudine, Tenofovir or Combination of Both in Immunotolerant Patients with Hepatitis B e Antigen-Positive Chronic Hepatitis B
N. Leung, E. Herrmann, G. Lau, H. Chan +5 more
2014Infectious Disease and Therapy8 citations Open access
Semantic Scholar
493 Phase III comparison of telbivudine vs lamivudine in HBeAg-positive patients with chronic hepatitis B: Efficacy, safety, and predictors of response at 1 year
E. Gane, Ching-Lung Lai, Y. Liaw, Satawat Thongsawat +9 more
20068 citations Open access
Semantic Scholar

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