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F. Schweizer · SciRah

Researcher profile · Semantic Scholar

F. Schweizer

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F. Schweizer — researcher profile on SciRah

h-index: 42
Works: 158
Citations: 7,424

Most-cited papers

Ceftazidime-Avibactam: a Novel Cephalosporin/β-lactamase Inhibitor Combination
G. Zhanel, Christopher D. Lawson, H. Adam, F. Schweizer +8 more
2013Drugs429 citations Open access
Semantic Scholar
Cefiderocol: A Siderophore Cephalosporin with Activity Against Carbapenem-Resistant and Multidrug-Resistant Gram-Negative Bacilli
G. Zhanel, A. Golden, S. Zelenitsky, Karyn Wiebe +11 more
2019Drugs388 citations
Semantic Scholar
Imipenem–Relebactam and Meropenem–Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations
G. Zhanel, Courtney K. Lawrence, H. Adam, F. Schweizer +10 more
2017Drugs356 citations
Semantic Scholar
Ceftolozane/Tazobactam: A Novel Cephalosporin/β-Lactamase Inhibitor Combination with Activity Against Multidrug-Resistant Gram-Negative Bacilli
G. Zhanel, Phillip Y. Chung, H. Adam, S. Zelenitsky +9 more
2013Drugs333 citations
Semantic Scholar
Review of Eravacycline, a Novel Fluorocycline Antibacterial Agent
G. Zhanel, D. Cheung, H. Adam, S. Zelenitsky +8 more
2016Drugs283 citations
Semantic Scholar
Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development
M. Jain, Anna M. Paczulla, T. Klonisch, Florence N. Dimgba +8 more
2013Journal of Cellular and Molecular Medicine233 citations Open access
Semantic Scholar
Antibiotic Hybrids: the Next Generation of Agents and Adjuvants against Gram-Negative Pathogens?
Ronald Domalaon, T. Idowu, G. Zhanel, F. Schweizer
2018Clinical Microbiology Reviews220 citations Open access
Semantic Scholar
Comparison of the next-generation aminoglycoside plazomicin to gentamicin, tobramycin and amikacin
G. Zhanel, Christopher D. Lawson, S. Zelenitsky, B. Findlay +8 more
2012Expert Review of Anti-Infective Therapy183 citations
Semantic Scholar
Tedizolid: A Novel Oxazolidinone with Potent Activity Against Multidrug-Resistant Gram-Positive Pathogens
G. Zhanel, R. Love, H. Adam, A. Golden +11 more
2015Drugs166 citations
Semantic Scholar
Oritavancin: mechanism of action.
G. Zhanel, F. Schweizer, J. Karlowsky
2012Clinical Infectious Diseases159 citations Open access
Semantic Scholar
Ceftaroline
G. Zhanel, G. Sniezek, F. Schweizer, S. Zelenitsky +5 more
2012Drugs137 citations Open access
Semantic Scholar
Antimicrobial susceptibility of 22746 pathogens from Canadian hospitals: results of the CANWARD 2007-11 study.
G. Zhanel, H. Adam, M. Baxter, J. Fuller +7 more
2013Journal of Antimicrobial Chemotherapy136 citations
Semantic Scholar
Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent
G. Zhanel, J. Esquivel, S. Zelenitsky, Courtney K. Lawrence +11 more
2020Drugs125 citations
Semantic Scholar
Ubiquitous Nature of Fluoroquinolones: The Oscillation between Antibacterial and Anticancer Activities
T. Idowu, F. Schweizer
2017Antibiotics101 citations Open access
Semantic Scholar
Adjuvants Based on Hybrid Antibiotics Overcome Resistance in Pseudomonas aeruginosa and Enhance Fluoroquinolone Efficacy.
B. Gorityala, Goutam Guchhait, Dinesh M. Fernando, Soumya R. Deo +4 more
2016Angewandte Chemie84 citations
Semantic Scholar
Amphiphilic Tobramycin-Lysine Conjugates Sensitize Multidrug Resistant Gram-Negative Bacteria to Rifampicin and Minocycline.
Y. Lyu, Xuan Yang, Sudeep Goswami, B. Gorityala +5 more
2017Journal of Medicinal Chemistry73 citations
Semantic Scholar
Cancer stem cells, cancer-initiating cells and methods for their detection.
Shiva Akbari-Birgani, Ted Paranjothy, A. Zuse, T. Janikowski +7 more
2016Drug Discovery Today72 citations
Semantic Scholar
Nuclear localized Akt enhances breast cancer stem-like cells through counter-regulation of p21Waf1/Cip1 and p27kip1
M. Jain, Jaganmohan Reddy Jangamreddy, J. Grabarek, F. Schweizer +3 more
2015Cell Cycle61 citations Open access
Semantic Scholar
The Anthelmintic Drug Niclosamide Synergizes with Colistin and Reverses Colistin Resistance in Gram-Negative Bacilli
Ronald Domalaon, P. D. De Silva, Ayush Kumar, G. Zhanel +1 more
2019Antimicrobial Agents and Chemotherapy60 citations Open access
Semantic Scholar
42936 pathogens from Canadian hospitals: 10 years of results (2007-16) from the CANWARD surveillance study.
G. Zhanel, H. Adam, M. Baxter, J. Fuller +11 more
2019Journal of Antimicrobial Chemotherapy59 citations
Semantic Scholar
Hybrid Antibiotic Overcomes Resistance in P. aeruginosa by Enhancing Outer Membrane Penetration and Reducing Efflux.
B. Gorityala, Goutam Guchhait, Sudeep Goswami, Dinesh M. Fernando +3 more
2016Journal of Medicinal Chemistry59 citations
Semantic Scholar
A Tobramycin Vector Enhances Synergy and Efficacy of Efflux Pump Inhibitors against Multidrug-Resistant Gram-Negative Bacteria.
Xuan Yang, Sudeep Goswami, B. Gorityala, Ronald Domalaon +4 more
2017Journal of Medicinal Chemistry57 citations Open access
Semantic Scholar
Short Antimicrobial Peptides and Peptide Scaffolds as Promising Antibacterial Agents.
Ronald Domalaon, G. Zhanel, F. Schweizer
2016Current Topics in Medicinal Chemistry51 citations
Semantic Scholar
Lefamulin: A Novel Oral and Intravenous Pleuromutilin for the Treatment of Community-Acquired Bacterial Pneumonia
G. Zhanel, C. Deng, S. Zelenitsky, Courtney K. Lawrence +12 more
2020Drugs50 citations
Semantic Scholar
Amphiphilic tobramycins with immunomodulatory properties.
Goutam Guchhait, A. Altieri, B. Gorityala, Xuan Yang +4 more
2015Angewandte Chemie48 citations
Semantic Scholar
Repurposed Antimicrobial Combination Therapy: Tobramycin-Ciprofloxacin Hybrid Augments Activity of the Anticancer Drug Mitomycin C Against Multidrug-Resistant Gram-Negative Bacteria
Ronald Domalaon, Derek Ammeter, Marc Brizuela, B. Gorityala +2 more
2019Frontiers in Microbiology46 citations Open access
Semantic Scholar
Antibacterial activity of amphiphilic tobramycin
Ramesh Dhondikubeer, Smritilekha Bera, G. Zhanel, F. Schweizer
2012Journal of antibiotics (Tokyo. 1968)46 citations
Semantic Scholar
Solithromycin: A Novel Fluoroketolide for the Treatment of Community-Acquired Bacterial Pneumonia
G. Zhanel, E. Hartel, H. Adam, S. Zelenitsky +10 more
2016Drugs45 citations
Semantic Scholar
Synthesis and antibacterial activity of amphiphilic lysine-ligated neomycin B conjugates.
Smritilekha Bera, G. Zhanel, F. Schweizer
2011Carbohydrate Research42 citations
Semantic Scholar
Ultrashort cationic lipopeptides and lipopeptoids: Evaluation and mechanistic insights against epithelial cancer cells.
Ronald Domalaon, B. Findlay, M. Ogunsina, G. Arthur +1 more
2016Peptides40 citations
Semantic Scholar
Synergistic combinations of anthelmintic salicylanilides oxyclozanide, rafoxanide, and closantel with colistin eradicates multidrug-resistant colistin-resistant Gram-negative bacilli
Ronald Domalaon, Oreofe Okunnu, G. Zhanel, F. Schweizer
2019Journal of antibiotics (Tokyo. 1968)39 citations
Semantic Scholar
Potentiation of β-lactam antibiotics and β-lactam/β-lactamase inhibitor combinations against MDR and XDR Pseudomonas aeruginosa using non-ribosomal tobramycin-cyclam conjugates.
T. Idowu, Derek Ammeter, G. Arthur, G. Zhanel +1 more
2019Journal of Antimicrobial Chemotherapy39 citations
Semantic Scholar
Investigating the antimicrobial peptide 'window of activity' using cationic lipopeptides with hydrocarbon and fluorinated tails.
B. Findlay, G. Zhanel, F. Schweizer
2012International Journal of Antimicrobial Agents38 citations
Semantic Scholar
Sulopenem: An Intravenous and Oral Penem for the Treatment of Urinary Tract Infections Due to Multidrug-Resistant Bacteria
G. Zhanel, Marianna Pozdirca, A. Golden, Courtney K. Lawrence +12 more
2022Drugs37 citations
Semantic Scholar
Heterodimeric Rifampicin-Tobramycin conjugates break intrinsic resistance of Pseudomonas aeruginosa to doxycycline and chloramphenicol in vitro and in a Galleria mellonella in vivo model.
T. Idowu, G. Arthur, G. Zhanel, F. Schweizer
2019European journal of medicinal chemistry36 citations
Semantic Scholar
Dilipid Ultrashort Tetrabasic Peptidomimetics (dUSTBPs) Potentiate Novobiocin and Rifampicin Against Multidrug-resistant Gram-negative Bacteria.
Danyel Ramirez, Liam Berry, Ronald Domalaon, Marc Brizuela +1 more
2020ACS Infectious Diseases35 citations
Semantic Scholar
Neomycin-phenolic conjugates: polycationic amphiphiles with broad-spectrum antibacterial activity, low hemolytic activity and weak serum protein binding.
B. Findlay, G. Zhanel, F. Schweizer
2012Bioorganic & Medicinal Chemistry Letters31 citations Open access
Semantic Scholar
Polymyxin B3-Tobramycin Hybrids with Pseudomonas aeruginosa-Selective Antibacterial Activity and Strong Potentiation of Rifampicin, Minocycline, and Vancomycin.
Ronald Domalaon, Xuan Yang, Y. Lyu, G. Zhanel +1 more
2017ACS Infectious Diseases29 citations
Semantic Scholar
Tobramycin-Linked Efflux Pump Inhibitor Conjugates Synergize Fluoroquinolones, Rifampicin and Fosfomycin against Multidrug-Resistant Pseudomonas aeruginosa
Xuan Yang, Ronald Domalaon, Y. Lyu, G. Zhanel +1 more
2018Journal of Clinical Medicine28 citations Open access
Semantic Scholar
Synthesis and Antibacterial Activities of Amphiphilic Neomycin B-based Bilipid Conjugates and Fluorinated Neomycin B-based Lipids
Smritilekha Bera, Ramesh Dhondikubeer, B. Findlay, G. Zhanel +1 more
2012Molecules28 citations Open access
Semantic Scholar
Guanidylation and Tail Effects in Cationic Antimicrobial Lipopeptoids
B. Findlay, Paul Szelemej, G. Zhanel, F. Schweizer
2012PLoS ONE27 citations Open access
Semantic Scholar
Homodimeric Tobramycin Adjuvant Repurposes Novobiocin as an Effective Antibacterial Agent against Gram-negative Bacteria.
T. Idowu, Derek Ammeter, Heather Rossong, G. Zhanel +1 more
2019Journal of Medicinal Chemistry26 citations Open access
Semantic Scholar
Short Proline-Rich Lipopeptide Potentiates Minocycline and Rifampin against Multidrug- and Extensively Drug-Resistant Pseudomonas aeruginosa
Ronald Domalaon, Yaroslav Sanchak, L. C. Koskei, Y. Lyu +3 more
2018Antimicrobial Agents and Chemotherapy26 citations Open access
Semantic Scholar
Amphiphilic Modulation of Glycosylated Antitumor Ether Lipids Results in a Potent Triamino Scaffold against Epithelial Cancer Cell Lines and BT474 Cancer Stem Cells.
T. Idowu, P. Samadder, G. Arthur, F. Schweizer
2017Journal of Medicinal Chemistry24 citations
Semantic Scholar
Structure–activity relationships in ultrashort cationic lipopeptides: the effects of amino acid ring constraint on antibacterial activity
Ronald Domalaon, Xuan Yang, J. O'Neil, G. Zhanel +2 more
2014Amino Acids24 citations
Semantic Scholar
Guanidinylated Polymyxins as Outer Membrane Permeabilizers Capable of Potentiating Rifampicin, Erythromycin, Ceftazidime and Aztreonam against Gram-Negative Bacteria
D. Ramirez, Danyel Ramirez, G. Arthur, G. Zhanel +1 more
2022Antibiotics22 citations Open access
Semantic Scholar
Amphiphilic lysine conjugated to tobramycin synergizes legacy antibiotics against wild‐type and multidrug‐resistant Pseudomonas aeruginosa
Y. Lyu, Ronald Domalaon, Xuan Yang, F. Schweizer
2019Biopolymers22 citations
Semantic Scholar
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria
Ronald Domalaon, Marc Brizuela, Benjamin Eisner, B. Findlay +2 more
2018Amino Acids22 citations
Semantic Scholar
Amphiphilic nebramine-based hybrids Rescue legacy antibiotics from intrinsic resistance in multidrug-resistant Gram-negative bacilli.
Xuan Yang, Derek Ammeter, T. Idowu, Ronald Domalaon +7 more
2019European journal of medicinal chemistry21 citations
Semantic Scholar
Cytotoxic properties of D-gluco-, D-galacto- and D-manno-configured 2-amino-2-deoxy-glycerolipids against epithelial cancer cell lines and BT-474 breast cancer stem cells.
P. Samadder, Yao-Zu Xu, F. Schweizer, G. Arthur
2014European journal of medicinal chemistry21 citations
Semantic Scholar

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