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A. Toker · SciRah

Researcher profile · Semantic Scholar

A. Toker

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A. Toker — researcher profile on SciRah

h-index: 18
Works: 32
Citations: 1,036

Most-cited papers

Active Demethylation of the Foxp3 Locus Leads to the Generation of Stable Regulatory T Cells within the Thymus
A. Toker, D. Engelbert, G. Garg, J. Polansky +14 more
2013Journal of Immunology267 citations
Semantic Scholar
Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors
A. Muik, E. Garralda, I. Altıntaş, F. Gieseke +34 more
2022Cancer Discovery99 citations Open access
Semantic Scholar
Regulatory T Cells in Ovarian Cancer Are Characterized by a Highly Activated Phenotype Distinct from that in Melanoma
A. Toker, L. Nguyen, S. Stone, S. Y. Cindy Yang +13 more
2018Clinical Cancer Research94 citations Open access
Semantic Scholar
Omicron BA.2 breakthrough infection enhances cross-neutralization of BA.2.12.1 and BA.4/BA.5
A. Muik, B. G. Lui, Maren Bacher, Ann-Kathrin Wallisch +9 more
2022bioRxiv73 citations Open access
Semantic Scholar
Turning the Tide Against Regulatory T Cells
SeongJun Han, A. Toker, Zhe-Qi Liu, P. Ohashi
2019Frontiers in Oncology53 citations Open access
Semantic Scholar
Naïve blood monocytes suppress T‐cell function. A possible mechanism for protection from autoimmunity
C. Slaney, A. Toker, A. L. La Flamme, B. Backstrom +1 more
2011Immunology and Cell Biology47 citations
Semantic Scholar
WAVE2 suppresses mTOR activation to maintain T cell homeostasis and prevent autoimmunity
Ming Liu, Jin-Yi Zhang, B. Pinder, Qing-Quan Liu +8 more
2021Science39 citations
Semantic Scholar
DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity
A. Muik, H. Adams, F. Gieseke, I. Altıntaş +20 more
2022Journal for ImmunoTherapy of Cancer38 citations Open access
Semantic Scholar
To Be or Not to Be a Treg Cell: Lineage Decisions Controlled by Epigenetic Mechanisms
A. Toker, J. Huehn
2011Science Signaling38 citations Open access
Semantic Scholar
Expression of costimulatory and inhibitory receptors in FoxP3+ regulatory T cells within the tumor microenvironment: Implications for combination immunotherapy approaches.
A. Toker, P. Ohashi
2019Advances in Cancer Research33 citations
Semantic Scholar
Glatiramer Acetate Treatment Directly Targets CD11b+Ly6G− Monocytes and Enhances the Suppression of Autoreactive T cells in Experimental Autoimmune Encephalomyelitis
A. Toker, C. Slaney, B. Backstrom, J. Harper
2011Scandinavian Journal of Immunology33 citations Open access
Semantic Scholar
Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer
Heather MacGregor, Carlos R. Garcia-Batres, A. Sayad, A. Elia +10 more
2019Oncoimmunology32 citations Open access
Semantic Scholar
Dynamic Imprinting of the Treg Cell-Specific Epigenetic Signature in Developing Thymic Regulatory T Cells
Susanne Herppich, A. Toker, Beate Pietzsch, Y. Kitagawa +6 more
2019Frontiers in Immunology28 citations Open access
Semantic Scholar
Exposure to BA.4/5 S protein drives neutralization of Omicron BA.1, BA.2, BA.2.12.1, and BA.4/5 in vaccine-experienced humans and mice
A. Muik, B. G. Lui, Maren Bacher, Ann-Kathrin Wallisch +27 more
2022Science immunology26 citations Open access
Semantic Scholar
Progressive loss of conserved spike protein neutralizing antibody sites in Omicron sublineages is balanced by preserved T cell immunity.
A. Muik, B. G. Lui, Jasmin Quandt, Huitian Diao +17 more
2023Cell Reports23 citations Open access
Semantic Scholar
Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells
G. Garg, Eirini Nikolouli, M. Hardtke-Wolenski, A. Toker +12 more
2017OncoTarget21 citations Open access
Semantic Scholar
An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation
A. Muik, I. Altıntaş, F. Gieseke, Kristina B Schoedel +17 more
2022Oncoimmunology20 citations Open access
Semantic Scholar
Foxp3+ regulatory T‐cell homeostasis quantitatively differs in murine peripheral lymph nodes and spleen
Pedro Milanez-Almeida, M. Meyer-Hermann, A. Toker, S. Khailaie +1 more
2015European Journal of Immunology18 citations Open access
Semantic Scholar
A Signal Integration Model of Thymic Selection and Natural Regulatory T Cell Commitment
S. Khailaie, Philippe A. Robert, A. Toker, J. Huehn +1 more
2014Journal of Immunology18 citations Open access
Semantic Scholar
Progressive loss of conserved spike protein neutralizing antibody sites in Omicron sublineages is balanced by preserved T-cell recognition epitopes
A. Muik, B. G. Lui, Huitian Diao, Yunguan Fu +14 more
2022bioRxiv12 citations Open access
Semantic Scholar
Immunity against conserved epitopes dominates after two consecutive exposures to SARS-CoV-2 Omicron BA.1.
A. Muik, Jasmin Quandt, B. G. Lui, Maren Bacher +11 more
2024Cell Reports10 citations Open access
Semantic Scholar
A modified superantigen rescues Ly6G− CD11b+ blood monocyte suppressor function and suppresses antigen-specific inflammation in EAE
C. Slaney, A. Toker, J. Fraser, J. Harper +1 more
2013Autoimmunity5 citations
Semantic Scholar
Exposure to BA.4/BA.5 Spike glycoprotein drives pan-Omicron neutralization in vaccine-experienced humans and mice
A. Muik, B. G. Lui, Maren Bacher, Ann-Kathrin Wallisch +27 more
2022bioRxiv4 citations Open access
Semantic Scholar
561 DuoBody®-PD-L1×4–1BB (GEN1046) induces superior immune-cell activation, cytokine production and cytotoxicity by combining PD-L1 blockade with conditional 4–1BB co-stimulation
A. Muik, I. Altıntaş, Rachelle E. Kosoff, F. Gieseke +13 more
20203 citations Open access
Semantic Scholar
1070 HexaBody-CD27 enhances T-cell activation, proliferation, cytokine secretion and cytotoxic activity independently of Fc gamma receptor-mediated crosslinking
Kristina B. Nürmberger, A. Imle, A. Toker, K. Strumane +16 more
2022Regular and Young Investigator Award Abstracts1 citations Open access
Semantic Scholar
Maximizing Return on Investment for the University of San Francisco Athletic Department Through Sponsorship
Carli Thomas, Rachel Sagapolu, Yi Wang, A. Toker
20121 citations
Semantic Scholar
Abstract 3283: GEN1046 (DuoBody®-PD-L1x4-1BB) in combination with PD-1 blockade potentiates anti-tumor immunity
M. Capello, A. Sette, T. Plantinga, Vanessa M. Spires +16 more
2023Cancer Research0 citations
Semantic Scholar
Abstract 1846: DuoBody-CD40×4-1BB (GEN1042) induces dendritic-cell maturation and enhances T-cell activation and effector functionsin vitroby conditional CD40 and 4-1BB agonist activity
A. Muik, Rachel Kosoff, F. Gieseke, I. Altıntaş +14 more
2021Immunology0 citations
Semantic Scholar
CommitmentSelection and Natural Regulatory T Cell A Signal Integration Model of Thymic
J. Huehn, M. Meyer-Hermann, S. Khailaie, Philippe A. Robert +1 more
20140 citations
Semantic Scholar
Targeting Antigen Presenting Cells to Treat Autoimmune Inflammation
A. Toker
20090 citations
Semantic Scholar
A modiﬁed superantigen rescues Ly6G 2 CD11b 1 blood monocyte suppressor function and suppresses antigen-speciﬁc inﬂammation in EAE
C. Slaney, A. Toker, John D. Fraser, Jacquie L. Harper +2 more
0 citations
Semantic Scholar
T Cells within the Thymus Leads to the Generation of Stable Regulatory Locus Foxp3 Active Demethylation of The
Siegfried Huehn, Shohei Weiss, Alf Hori, J. Hamann +33 more
0 citations
Semantic Scholar

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