L. De Rosa

Most-cited papers

1. Regeneration of the entire human epidermis by transgenic stem cells

   T. Hirsch, T. Rothoeft, N. Teig, J. Bauer +22 more

   2017Nature458 citations Open access

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2. Transcriptional repression of miR-34 family contributes to p63-mediated cell cycle progression in epidermal cells.

   D. Antonini, M. Russo, L. De Rosa, Marisa Gorrese +2 more

   2010Journal of Investigative Dermatology139 citations Open access

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3. Long-Term Stability and Safety of Transgenic Cultured Epidermal Stem Cells in Gene Therapy of Junctional Epidermolysis Bullosa

   L. De Rosa, Sonia Carulli, F. Cocchiarella, D. Quaglino +7 more

   2013Stem Cell Reports134 citations Open access

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4. Closure of a Large Chronic Wound through Transplantation of Gene-Corrected Epidermal Stem Cells.

   J. Bauer, J. Koller, E. Murauer, L. De Rosa +11 more

   2017Journal of Investigative Dermatology116 citations Open access

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5. p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome

   G. Ferone, M. R. Mollo, Helen A. Thomason, D. Antonini +8 more

   2012Human Molecular Genetics85 citations Open access

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6. Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome

   G. Ferone, Helen A. Thomason, D. Antonini, L. De Rosa +14 more

   2012EMBO Molecular Medicine84 citations Open access

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7. Laminin 332-Dependent YAP Dysregulation Depletes Epidermal Stem Cells in Junctional Epidermolysis Bullosa.

   L. De Rosa, Alessia Secone Seconetti, G. De Santis, G. Pellacani +6 more

   2019Cell Reports78 citations Open access

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8. Extrameningeal solitary fibrous tumors—surgery alone or surgery plus perioperative radiotherapy: A retrospective study from the global solitary fibrous tumor initiative in collaboration with the Sarcoma Patients EuroNet

   R. Haas, I. Walraven, E. Lecointe-Artzner, W. V. van Houdt +16 more

   2020Cancer75 citations Open access

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9. Gentamicin induces LAMB3 nonsense mutation readthrough and restores functional laminin 332 in junctional epidermolysis bullosa

   Vadim Lincoln, J. Cogan, Yingping Hou, M. Hirsch +7 more

   2018Proceedings of the National Academy of Sciences of the United States of America67 citations Open access

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10. TAp63 Is Important for Cardiac Differentiation of Embryonic Stem Cells and Heart Development

    M. Rouleau, Alain Medawar, L. Hamon, Shoham Shivtiel +11 more

    2011Stem Cells57 citations Open access

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11. p63 Suppresses Non-epidermal Lineage Markers in a Bone Morphogenetic Protein-dependent Manner via Repression of Smad7*

    L. De Rosa, D. Antonini, G. Ferone, M. Russo +3 more

    2009Journal of Biological Chemistry49 citations Open access

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12. Transgenic Epidermal Cultures for Junctional Epidermolysis Bullosa - 5-Year Outcomes.

    M. Kueckelhaus, T. Rothoeft, L. De Rosa, Burcu Yeni +8 more

    2021New England Journal of Medicine39 citations Open access

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13. Cell biology: Dormant and restless skin stem cells

    L. De Rosa, M. De Luca

    2012Nature39 citations Open access

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14. Amplicon‐based next‐generation sequencing: an effective approach for the molecular diagnosis of epidermolysis bullosa

    E. Tenedini, L. Artuso, I. Bernardis, V. Artusi +9 more

    2015British Journal of Dermatology37 citations Open access

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15. Toward Combined Cell and Gene Therapy for Genodermatoses.

    L. De Rosa, M. Latella, Alessia Secone Seconetti, Cecilia Cattelani +3 more

    2020Cold Spring Harbor Perspectives in Biology32 citations Open access

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16. Methimazole embryopathy: a contribution to defining the phenotype.

    R. Valdez, P. Barbero, R. Liascovich, L. De Rosa +2 more

    2007Reproductive Toxicology31 citations

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17. Correction of Recessive Dystrophic Epidermolysis Bullosa by Transposon-Mediated Integration of COL7A1 in Transplantable Patient-Derived Primary Keratinocytes.

    M. Latella, F. Cocchiarella, L. De Rosa, G. Turchiano +4 more

    2017Journal of Investigative Dermatology30 citations Open access

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18. Hologene 5: A Phase II/III Clinical Trial of Combined Cell and Gene Therapy of Junctional Epidermolysis Bullosa

    L. De Rosa, E. Enzo, Giulia Zardi, C. Bodemer +3 more

    2021Frontiers in Genetics29 citations Open access

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19. Tprg, a gene predominantly expressed in skin, is a direct target of the transcription factor p63.

    D. Antonini, M. Dentice, Parvesh Mahtani, L. De Rosa +5 more

    2008Journal of Investigative Dermatology28 citations Open access

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20. Management of meningeal solitary fibrous tumors/hemangiopericytoma; surgery alone or surgery plus postoperative radiotherapy?

    R. Haas, I. Walraven, E. Lecointe-Artzner, W. V. van Houdt +19 more

    2020Acta oncologica26 citations Open access

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21. Epigenetic and metabolic regulation of epidermal homeostasis

    Roland N. Wagner, Josefina Piñón Hofbauer, V. Wally, B. Kofler +4 more

    2021Experimental Dermatology25 citations Open access

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22. The long and winding road that leads to a cure for epidermolysis bullosa.

    Sonia Carulli, R. Contin, L. De Rosa, G. Pellegrini +1 more

    2013Regenerative medicine24 citations Open access

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23. Allele-specific CRISPR-Cas9 editing of dominant epidermolysis bullosa simplex in human epidermal stem cells

    C. Cattaneo, E. Enzo, L. De Rosa, L. Sercia +11 more

    2023Molecular Therapy21 citations Open access

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24. Fighting the Huntington’s Disease with a G-Quadruplex-Forming Aptamer Specifically Binding to Mutant Huntingtin Protein: Biophysical Characterization, In Vitro and In Vivo Studies

    Claudia Riccardi, Federica D'Aria, F. Digilio, M. Carillo +7 more

    2022International Journal of Molecular Sciences15 citations Open access

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25. Stairways to Advanced Therapies for Epidermolysis Bullosa.

    L. De Rosa, E. Enzo, Michele Palamenghi, Laura Sercia +1 more

    2022Cold Spring Harbor Perspectives in Biology12 citations

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26. Nuck cyst: a rare cause of inguinal swelling in infancy.

    A. Papparella, S. Vaccaro, M. Accardo, L. De Rosa +2 more

    2018Minerva Pediatrica12 citations

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27. Clinical outcomes and complications of S53P4 bioactive glass in chronic osteomyelitis and septic non-unions: a retrospective single-center study

    S. Gatti, D. Gaddi, M. Turati, Giulio Leone +6 more

    2024European Journal of Clinical Microbiology and Infectious Diseases11 citations Open access

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28. Truncated Analogues of a G-Quadruplex-Forming Aptamer Targeting Mutant Huntingtin: Shorter Is Better!

    Claudia Riccardi, Federica D'Aria, D. Fasano, F. Digilio +7 more

    2022International Journal of Molecular Sciences11 citations Open access

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29. Non-Union Scoring System (NUSS): Is It Enough in Clinical Practice?

    D. Gaddi, S. Gatti, M. Piatti, Andrea Poli +5 more

    2022Indian Journal of Orthopaedics11 citations Open access

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30. Laparoscopic Fowler-Stephens orchidopexy for intra-abdominal cryptorchid testis: a single institution experience.

    A. Papparella, L. De Rosa, C. Noviello

    2021La Pediatria Medica e Chirurgica10 citations Open access

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31. Toward sutureless laparoscopic inguinal hernia repair in children?

    A. Marte, L. De Rosa, L. Pintozzi, V. Esposito

    2019La Pediatria Medica e Chirurgica9 citations Open access

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32. AlPaCas: allele-specific CRISPR gene editing through a protospacer-adjacent-motif (PAM) approach

    Serena Rosignoli, Elisa Lustrino, Alessio Conci, A. Fabrizi +7 more

    2024Nucleic Acids Research8 citations Open access

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33. Contemporary role of amputation for patients with extremity soft tissue sarcoma.

    L. Conti, F. Buriro, M. Baia, S. Pasquali +4 more

    2022European Journal of Surgical Oncology8 citations

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34. The steep uphill path leading to ex vivo gene therapy for genodermatoses.

    Michele Palamenghi, M. De Luca, L. De Rosa

    2022American Journal of Physiology - Cell Physiology8 citations

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35. A cellular disease model toward gene therapy of TGM1-dependent lamellar ichthyosis

    L. Sercia, Oriana Romano, Grazia Marini, E. Enzo +3 more

    2024Molecular Therapy: Methods & Clinical Development7 citations Open access

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36. The joint battle to tackle epidermolysis bullosa through gene therapy.

    L. De Rosa, M. De Luca

    2022Trends in Molecular Medicine7 citations Open access

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37. Down Syndrome Fetal Fibroblasts Display Alterations of Endosomal Trafficking Possibly due to SYNJ1 Overexpression

    L. De Rosa, D. Fasano, Lucrezia Zerillo, V. Valente +12 more

    2022Frontiers in Genetics6 citations Open access

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38. Transscrotal orchidopexy for palpable cryptorchid testis: follow-up and outcomes.

    A. Papparella, G. Cobellis, L. De Rosa, C. Noviello

    2018La Pediatria Medica e Chirurgica6 citations Open access

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39. Dormant and restless skin stem cells

    L. De Rosa, M. De Luca

    2012Nature6 citations Open access

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40. Suppresses Non-epidermal Lineage Markers in a Bone Morphogenetic Protein-dependent Manner via Repression of Smad 7 *

    L. De Rosa, D. Antonini, G. Ferone, M. Russo +3 more

    20096 citations

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41. Expanding SPG18 clinical spectrum: autosomal dominant mutation causes complicated hereditary spastic paraplegia in a large family

    Assunta Trinchillo, Valeria Valente, Marcello Esposito, Miriana Migliaccio +11 more

    2024Neurological Sciences3 citations Open access

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42. Advances on potential therapeutic options for epidermolysis bullosa

    L. De Rosa, U. Koller, J. Bauer, M. De Luca +1 more

    20183 citations Open access

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43. Orthoplastic Management of Lower Limb Traumas

    Arianna Gatto, S. Stucchi, Leonardo Brambilla, E. Cavalli +7 more

    2024Annals of Plastic Surgery2 citations

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44. AMPLICON-BASED NGS: AN EFFECTIVE APPROACH FOR THE MOLECULAR DIAGNOSIS OF EPIDERMOLYSIS BULLOSA

    E. Tenedini, L. Artuso, I. Bernardis, V. Artusi +8 more

    20152 citations

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45. Base-edited skin equivalents: A promising ex vivo approach for recessive dystrophic epidermolysis bullosa.

    A. Fabrizi, L. De Rosa

    2026Molecular Therapy1 citations Open access

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46. A road map through the multi‐faceted world of female genital cosmetic surgical techniques

    Giovanni Buzzaccarini, R. Degliuomini, L. De Rosa, Silvia Villa +4 more

    2025International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics1 citations Open access

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47. Laparoscopic surgery in children: abdominal wall complications

    S. Vaccaro, L. De Rosa, A. Papparella

    20171 citations

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48. Abstract 2520: Clinical impact of the personalized medicine for neuroblastoma patients: Six years of experience of the PREME program

    F. Parisi, E. Ciampi, Veronica Bensa, F. Serafino +9 more

    2026Cancer Research0 citations

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49. Gene therapy for genodermatoses at the crossroads of innovation and clinical translation

    A. Fabrizi, Marta Valenti, Silvia Zacchino, Katia Russo +3 more

    2026Frontiers in Bioengineering and Biotechnology0 citations Open access

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50. Sexual dimorphism in epidermal stem cell dynamics.

    D. Engelman, Joel Hochstetter, A. Bauduin, Sagar Patil +14 more

    2026Nature0 citations Open access

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