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D. Jump · SciRah

Researcher profile · Semantic Scholar

D. Jump

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D. Jump — researcher profile on SciRah

h-index: 58
Works: 166
Citations: 14K

Most-cited papers

Role of gut microbiota in type 2 diabetes pathophysiology
M. Gurung, Zhi-Peng Li, H. You, R. Rodrigues +3 more
2020EBioMedicine1,480 citations Open access
Semantic Scholar
The Biochemistry of n-3 Polyunsaturated Fatty Acids* 210
D. Jump
2002Journal of Biological Chemistry662 citations Open access
Semantic Scholar
Fatty Acid Regulation of Gene Transcription
D. Jump
2004Critical reviews in clinical laboratory sciences614 citations
Semantic Scholar
Fatty acid regulation of hepatic gene transcription.
D. Jump, D. Botolin, Yun Wang, Jing-Hua Xu +2 more
2005Journal of NutriLife469 citations Open access
Semantic Scholar
N-3 polyunsaturated fatty acid regulation of hepatic gene transcription
D. Jump
2008Current Opinion in Lipidology444 citations Open access
Semantic Scholar
Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity Published, JLR Papers in Press, June 21, 2006.
Yun Wang, D. Botolin, Jing-Hua Xu, Barbara D. Christian +7 more
2006Journal of Lipid Research333 citations Open access
Semantic Scholar
Tissue-specific, nutritional, and developmental regulation of rat fatty acid elongases Published, JLR Papers in Press, January 16, 2005. DOI 10.1194/jlr.M400335-JLR200
Yun Wang, D. Botolin, Barbara D. Christian, J. Busik +2 more
2005Journal of Lipid Research275 citations Open access
Semantic Scholar
Fatty acid regulation of hepatic lipid metabolism
D. Jump
2011Current opinion in clinical nutrition and metabolic care271 citations Open access
Semantic Scholar
Fatty Acid–Regulated Transcription Factors in the Liver
D. Jump, S. Tripathy, C. Depner
2013Annual review of nutrition226 citations Open access
Semantic Scholar
Omega-3 fatty acid supplementation and cardiovascular disease
D. Jump, C. Depner, S. Tripathy
2012Journal of Lipid Research225 citations Open access
Semantic Scholar
Unsaturated Fatty Acid Regulation of Peroxisome Proliferator-activated Receptor α Activity in Rat Primary Hepatoctes*
Anjali S Pawar, D. Jump
2003Journal of Biological Chemistry210 citations Open access
Semantic Scholar
Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDD-Mediated hepatotoxicity.
D. Boverhof, L. Burgoon, C. Tashiro, B. Chittim +3 more
2005Toxicological Sciences197 citations Open access
Semantic Scholar
Anti-inflammatory effect of docosahexaenoic acid on cytokine-induced adhesion molecule expression in human retinal vascular endothelial cells.
Wei-Qin Chen, W. J. Esselman, D. Jump, J. Busik
2005Investigative Ophthalmology and Visual Science172 citations
Semantic Scholar
Docosahexaenoic acid (DHA) and hepatic gene transcription.
D. Jump, D. Botolin, Yun Wang, Jing-Hua Xu +2 more
2008Chemistry and Physics of Lipids165 citations Open access
Semantic Scholar
Docosahexaneoic acid (22:6,n-3) regulates rat hepatocyte SREBP-1 nuclear abundance by Erk- and 26S proteasome-dependent pathways Published, JLR Papers in Press, October 12, 2005.
D. Botolin, Yun Wang, Barbara D. Christian, D. Jump
2006Journal of Lipid Research158 citations Open access
Semantic Scholar
Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes
R. Rodrigues, M. Gurung, Zhi-Peng Li, Manuel García-Jaramillo +16 more
2021Nature Communications144 citations Open access
Semantic Scholar
Growth Hormone Regulates the Balance Between Bone Formation and Bone Marrow Adiposity
P. J. Menagh, R. Turner, D. Jump, C. Wong +4 more
2009Journal of Bone and Mineral Research143 citations Open access
Semantic Scholar
Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.
C. Depner, Kenneth A. Philbrick, D. Jump
2013Journal of NutriLife142 citations Open access
Semantic Scholar
The Role of Liver X Receptor-α in the Fatty Acid Regulation of Hepatic Gene Expression*
Anjali S Pawar, D. Botolin, D. Mangelsdorf, D. Jump
2003Journal of Biological Chemistry142 citations Open access
Semantic Scholar
Omega-3 Polyunsaturated Fatty Acids as a Treatment Strategy for Nonalcoholic Fatty Liver Disease
D. Jump, K. Lytle, C. Depner, S. Tripathy
2017Pharmacology and Therapeutics134 citations Open access
Semantic Scholar
Remodeling of Retinal Fatty Acids in an Animal Model of Diabetes
M. Tikhonenko, T. Lydic, Yun Wang, Wei-Qin Chen +8 more
2009Diabetes134 citations Open access
Semantic Scholar
Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation
D. Jump, M. Torres-Gonzalez, L. Olson
2010Biochemical Pharmacology120 citations Open access
Semantic Scholar
Mammalian Fatty Acid Elongases
D. Jump
2009Methods in molecular biology116 citations Open access
Semantic Scholar
Inhibition of cytokine signaling in human retinal endothelial cells through modification of caveolae/lipid rafts by docosahexaenoic acid.
Wei-Qin Chen, D. Jump, W. J. Esselman, J. Busik
2007Investigative Ophthalmology and Visual Science115 citations Open access
Semantic Scholar
Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species[S]
C. Green, Cansel G. Ozguden-Akkoc, Yun Wang, D. Jump +1 more
2010Journal of Lipid Research114 citations Open access
Semantic Scholar
Dyslipidemia, but not hyperglycemia, induces inflammatory adhesion molecules in human retinal vascular endothelial cells.
Wei-Qin Chen, D. Jump, M. Grant, W. J. Esselman +1 more
2003Investigative Ophthalmology and Visual Science95 citations Open access
Semantic Scholar
Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer.
D. Jump, C. Depner, S. Tripathy, K. Lytle
2015Advances in Nutrition83 citations Open access
Semantic Scholar
Regulation of Rat Hepatic L-Pyruvate Kinase Promoter Composition and Activity by Glucose, n-3 Polyunsaturated Fatty Acids, and Peroxisome Proliferator-activated Receptor-α Agonist*
Jing-Hua Xu, Barbara D. Christian, D. Jump
2006Journal of Biological Chemistry79 citations Open access
Semantic Scholar
Fatty Acid Regulation of Liver X Receptors (LXR) and Peroxisome Proliferator-activated Receptor α (PPARα) in HEK293 Cells*
Anjali S Pawar, Jing-Hua Xu, Erik Jerks, D. Mangelsdorf +1 more
2002Journal of Biological Chemistry75 citations Open access
Semantic Scholar
The role of liver X receptor-alpha in the fatty acid regulation of hepatic gene expression.
Anjali S Pawar, D. Botolin, D. Mangelsdorf, D. Jump
2003Journal of Biological Chemistry74 citations
Semantic Scholar
Elevated hepatic fatty acid elongase-5 activity corrects dietary fat-induced hyperglycemia in obese BL/6J mice[S]
S. Tripathy, M. Torres-Gonzalez, D. Jump
2010Journal of Lipid Research68 citations Open access
Semantic Scholar
Omega-3 Fatty Acids and Nonalcoholic Fatty Liver Disease in Adults and Children: Where Do We Stand?
Melinda H. Spooner, D. Jump
2019Current opinion in clinical nutrition and metabolic care63 citations Open access
Semantic Scholar
A Metabolomic Analysis of Omega-3 Fatty Acid-Mediated Attenuation of Western Diet-Induced Nonalcoholic Steatohepatitis in LDLR -/- Mice
C. Depner, M. Traber, G. Bobe, Elizabeth Kensicki +3 more
2013PLoS ONE62 citations Open access
Semantic Scholar
Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice
K. Lytle, C. Wong, D. Jump
2017PLoS ONE56 citations Open access
Semantic Scholar
Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice[S]
S. Tripathy, K. Lytle, R. Stevens, J. Bain +4 more
2014Journal of Lipid Research53 citations Open access
Semantic Scholar
Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice[S]
S. Tripathy, D. Jump
2013Journal of Lipid Research53 citations Open access
Semantic Scholar
Lipidomic and transcriptomic analysis of western diet-induced nonalcoholic steatohepatitis (NASH) in female Ldlr -/- mice
Manuel García-Jaramillo, Melinda H. Spooner, C. Löhr, C. Wong +2 more
2019PLoS ONE52 citations Open access
Semantic Scholar
Nonalcoholic Fatty Liver Disease and Omega-3 Fatty Acids: Mechanisms and Clinical Use
Melinda H. Spooner, D. Jump
2023Annual review of nutrition51 citations Open access
Semantic Scholar
Menhaden oil decreases high-fat diet-induced markers of hepatic damage, steatosis, inflammation, and fibrosis in obese Ldlr-/- mice.
C. Depner, M. Torres-Gonzalez, S. Tripathy, G. Milne +1 more
2012Journal of NutriLife50 citations Open access
Semantic Scholar
Vitamin E deficiency decreases long-chain PUFA in zebrafish (Danio rerio).
K. Lebold, D. Jump, Galen W. Miller, Charlotte L. Wright +4 more
2011Journal of NutriLife48 citations Open access
Semantic Scholar
Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis in Ldlr−/− mice by targeting the TGFβ-Smad3 pathway[S]
K. Lytle, C. Depner, C. Wong, D. Jump
2015Journal of Lipid Research46 citations Open access
Semantic Scholar
Novel liquid chromatography–mass spectrometry method shows that vitamin E deficiency depletes arachidonic and docosahexaenoic acids in zebrafish (Danio rerio) embryos
K. Lebold, J. Kirkwood, Alan W. Taylor, Jaewoo Choi +7 more
2013Redox Biology44 citations Open access
Semantic Scholar
Selective Proteolytic Processing of Rat Hepatic Sterol Regulatory Element Binding Protein-1 (SREBP-1) and SREBP–2 During Postnatal Development*
D. Botolin, D. Jump
2003Journal of Biological Chemistry41 citations Open access
Semantic Scholar
Elevated insulin secretion from liver X receptor-activated pancreatic beta-cells involves increased de novo lipid synthesis and triacylglyceride turnover.
C. Green, D. Jump, L. Olson
2009Endocrinology39 citations Open access
Semantic Scholar
Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible?
K. Lytle, D. Jump
2016PLoS ONE36 citations Open access
Semantic Scholar
Impact of dietary fat on the development of non-alcoholic fatty liver disease in Ldlr−/− mice
D. Jump, C. Depner, S. Tripathy, K. Lytle
2015Proceedings of the Nutrition Society36 citations Open access
Semantic Scholar
Thermoneutral housing attenuates premature cancellous bone loss in male C57BL/6J mice
Stephen A. Martin, Kenneth A. Philbrick, C. Wong, D. A. Olson +7 more
2019Endocrine Connections33 citations Open access
Semantic Scholar
Polyunsaturated fatty acid regulation of hepatic gene transcription
S. Clarke, D. Jump
2007Lipids33 citations
Semantic Scholar
A Lipidomic Analysis of Docosahexaenoic Acid (22:6, ω3) Mediated Attenuation of Western Diet Induced Nonalcoholic Steatohepatitis in Male Ldlr -/- Mice
Manuel García-Jaramillo, K. Lytle, Melinda H. Spooner, D. Jump
2019Metabolites31 citations Open access
Semantic Scholar
Fatty acid regulation of liver X receptors (LXR) and peroxisome proliferator-activated receptor alpha (PPARalpha ) in HEK293 cells.
Anjali S Pawar, Jing-Hua Xu, Erik Jerks, D. Mangelsdorf +1 more
2002Journal of Biological Chemistry30 citations
Semantic Scholar

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S. Tripathy×9
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S. Tripathy — researcher profile on SciRah
C. Depner×9
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C. Depner — researcher profile on SciRah
D. Botolin×8
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D. Botolin — researcher profile on SciRah
K. Lytle×8
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Yun Wang — researcher profile on SciRah

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Jing-Hua Xu — researcher profile on SciRah

Barbara D. Christian×6

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Barbara D. Christian — researcher profile on SciRah

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J. Busik — researcher profile on SciRah

Anjali S Pawar×5

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Anjali S Pawar — researcher profile on SciRah

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C. Wong — researcher profile on SciRah

Wei-Qin Chen×4

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Wei-Qin Chen — researcher profile on SciRah

D. Mangelsdorf×4

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D. Mangelsdorf — researcher profile on SciRah