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Shing-Hwa Liu · SciRah

Researcher profile · Semantic Scholar

Shing-Hwa Liu

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Shing-Hwa Liu — researcher profile on SciRah

h-index: 60
Works: 327
Citations: 12K

Most-cited papers

The antifibrotic and anti-inflammatory effects of icariin on the kidney in a unilateral ureteral obstruction mouse model.
Hsin-An Chen, Chang-Mu Chen, Siao-Syun Guan, Chih-Kang Chiang +2 more
2019Phytomedicine69 citations
Semantic Scholar
Methylmercury exposure induces ROS/Akt inactivation-triggered endoplasmic reticulum stress-regulated neuronal cell apoptosis.
Yao-Pang Chung, C. Yen, Feng-Cheng Tang, Kuan-I. Lee +6 more
2019Toxicology64 citations
Semantic Scholar
Antidiabetic Properties of Chitosan and Its Derivatives
Huei-Ping Tzeng, Shing-Hwa Liu, Meng-Tsan Chiang
2022Marine Drugs57 citations Open access
Semantic Scholar
Omega-3 Fatty Acids-Enriched Fish Oil Activates AMPK/PGC-1α Signaling and Prevents Obesity-Related Skeletal Muscle Wasting
Shing-Hwa Liu, Chen-Yuan Chiu, Lou-Pin Wang, Meng-Tsan Chiang
2019Marine Drugs44 citations Open access
Semantic Scholar
Comparative Effects and Mechanisms of Chitosan and Its Derivatives on Hypercholesterolemia in High-Fat Diet-Fed Rats
Chen-Yuan Chiu, T. Yen, Shing-Hwa Liu, Meng-Tsan Chiang
2019International Journal of Molecular Sciences41 citations Open access
Semantic Scholar
Arsenic induces human chondrocyte senescence and accelerates rat articular cartilage aging
Yao-Pang Chung, Ya-Wen Chen, Te I. Weng, Rong-Sen Yang +1 more
2019Archives of Toxicology40 citations
Semantic Scholar
Acute oral toxicity and repeated dose 28-day oral toxicity studies of MIL-101 nanoparticles.
Chia-Hung Liu, Hsien‐Chun Chiu, Hsiang-ling Sung, Jyun‐Yi Yeh +2 more
2019Regulatory toxicology and pharmacology : RTP39 citations
Semantic Scholar
Biocompatible and multifunctional gold nanorods for effective photothermal therapy of oral squamous cell carcinoma
Yu‐Te Liao, Chia-Hung Liu, Y. Chin, Sin-Yuan Chen +3 more
2019Journal of materials chemistry. B39 citations
Semantic Scholar
Cadmium exposure induces pancreatic β-cell death via a Ca2+-triggered JNK/CHOP-related apoptotic signaling pathway.
Cheng-Chin Huang, Chun-Ying Kuo, Ching-Yao Yang, Jui-Ming Liu +7 more
2019Toxicology38 citations
Semantic Scholar
Methylmercury Induces Mitochondria- and Endoplasmic Reticulum Stress-Dependent Pancreatic β-Cell Apoptosis via an Oxidative Stress-Mediated JNK Signaling Pathway
Ching-Yao Yang, Shing-Hwa Liu, Chin-Chuan Su, Kai-Min Fang +8 more
2022International Journal of Molecular Sciences37 citations Open access
Semantic Scholar
Chlorpyrifos induces neuronal cell death via both oxidative stress and Akt activation downstream-regulated CHOP-triggered apoptotic pathways.
Jhe-Wei Lin, Shih-Chang Fu, Jui-Ming Liu, Shing-Hwa Liu +8 more
2022Toxicology in Vitro36 citations
Semantic Scholar
Roles of ERK/Akt signals in mitochondria-dependent and endoplasmic reticulum stress-triggered neuronal cell apoptosis induced by 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene, a major active metabolite of bisphenol A.
Chun-Fa Huang, Shing-Hwa Liu, Chin-Chuan Su, Kai-Min Fang +7 more
2021Toxicology35 citations
Semantic Scholar
Naringin Improves Osteoblast Mineralization and Bone Healing and Strength through Regulating Estrogen Receptor Alpha-Dependent Alkaline Phosphatase Gene Expression.
Gong-Jhe Wu, Kung-Yen Chen, Jr-Di Yang, Shing-Hwa Liu +1 more
2021Journal of Agricultural and Food Chemistry34 citations
Semantic Scholar
Arsenic induces autophagy-dependent apoptosis via Akt inactivation and AMPK activation signaling pathways leading to neuronal cell death.
Shih-Chang Fu, Jhe-Wei Lin, Jui-Ming Liu, Shing-Hwa Liu +7 more
2021Neurotoxicology34 citations
Semantic Scholar
Withaferin A protects against endoplasmic reticulum stress-associated apoptosis, inflammation, and fibrosis in the kidney of a mouse model of unilateral ureteral obstruction.
Chang-Mu Chen, Yao-Pang Chung, Chia-Hung Liu, Kuo-Tong Huang +4 more
2020Phytomedicine34 citations
Semantic Scholar
Genistein Improves Bone Healing via Triggering Estrogen Receptor Alpha-Mediated Expressions of Osteogenesis-Associated Genes and Consequent Maturation of Osteoblasts.
Gong-Jhe Wu, Jui-Tai Chen, Y. Cherng, Chuen-Chau Chang +2 more
2020Journal of Agricultural and Food Chemistry34 citations
Semantic Scholar
The Anti-Obesity Effect of Polysaccharide-Rich Red Algae (Gelidium amansii) Hot-Water Extracts in High-Fat Diet-Induced Obese Hamsters
Tsung-Han Yang, Chen-Yuan Chiu, Ting-Jang Lu, Shing-Hwa Liu +1 more
2019Marine Drugs34 citations Open access
Semantic Scholar
Low-dose tributyltin exposure induces an oxidative stress-triggered JNK-related pancreatic β-cell apoptosis and a reversible hypoinsulinemic hyperglycemia in mice
Chun-Fa Huang, Ching-Yao Yang, Jing-Ren Tsai, Cheng-Tien Wu +2 more
2018Scientific Reports34 citations Open access
Semantic Scholar
Quercetin induces tongue squamous cell carcinoma cell apoptosis via the JNK activation-regulated ERK/GSK-3α/β-mediated mitochondria-dependent apoptotic signaling pathway
Chun-Fa Huang, Shing-Hwa Liu, Tsung-Jung Ho, Kuan-I. Lee +5 more
2022Oncology Letters33 citations Open access
Semantic Scholar
Functional Comparison of High and Low Molecular Weight Chitosan on Lipid Metabolism and Signals in High-Fat Diet-Fed Rats
Shing-Hwa Liu, Chen-Yuan Chiu, Ching-Ming Shi, Meng-Tsan Chiang
2018Marine Drugs33 citations Open access
Semantic Scholar
Targeting histone deacetylase-3 blocked epithelial-mesenchymal plasticity and metastatic dissemination in gastric cancer
Sheng-Mao Wu, Y. Jan, Shih C. Tsai, Hung-Chuan Pan +9 more
2021Cell Biology and Toxicology31 citations Open access
Semantic Scholar
Effects and Mechanisms of Chitosan and ChitosanOligosaccharide on Hepatic Lipogenesis and Lipid Peroxidation, Adipose Lipolysis, and Intestinal Lipid Absorption in Rats with High-Fat Diet-Induced Obesity
Shing-Hwa Liu, Rui-Yi Chen, Meng-Tsan Chiang
2021International Journal of Molecular Sciences31 citations Open access
Semantic Scholar
Early Elimination of Uremic Toxin Ameliorates AKI to CKD Transition.
Jia-Huang Chen, Chia-Ter Chao, Jenq-Wen Huang, Kuan-Yu Hung +3 more
2021Clinical science31 citations Open access
Semantic Scholar
Low Intensity Pulsed Ultrasound Prevents Recurrent Ischemic Stroke in a Cerebral Ischemia/Reperfusion Injury Mouse Model via Brain-derived Neurotrophic Factor Induction
Cheng-Tien Wu, Ting-hua Yang, Man-Chih Chen, Yao-Pang Chung +4 more
2019International Journal of Molecular Sciences30 citations Open access
Semantic Scholar
The Deubiquitinating Enzyme Inhibitor PR-619 Enhances the Cytotoxicity of Cisplatin via the Suppression of Anti-Apoptotic Bcl-2 Protein: In Vitro and In Vivo Study
Kuan-Lin Kuo, Shing-Hwa Liu, Wei-Chou Lin, Po-Ming Chow +7 more
2019Cells29 citations Open access
Semantic Scholar
Bioactive Flavonoids Icaritin and Icariin Protect against Cerebral Ischemia–Reperfusion-Associated Apoptosis and Extracellular Matrix Accumulation in an Ischemic Stroke Mouse Model
Cheng-Tien Wu, Man-Chih Chen, Shing-Hwa Liu, Ting-hua Yang +3 more
2021Biomedicines28 citations Open access
Semantic Scholar
Neddylation inhibitor, MLN4924 suppresses angiogenesis in huvecs and solid cancers: in vitro and in vivo study.
Chung-Sheng Shi, Kuan-Lin Kuo, Wei-Chou Lin, Mei Chen +6 more
2020American Journal of Cancer Research28 citations
Semantic Scholar
ANGPTL1 attenuates cancer migration, invasion, and stemness through regulating FOXO3a-mediated SOX2 expression in colorectal cancer
Ting-Yu Chang, Kuo-Cheng Lan, Chen-Yuan Chiu, M. Sheu +1 more
2022Clinical science27 citations Open access
Semantic Scholar
Honokiol enhances temozolomide-induced apoptotic insults to malignant glioma cells via an intrinsic mitochondrion-dependent pathway.
C. Chio, Yu-Ting Tai, Mahendravarman Mohanraj, Shing-Hwa Liu +2 more
2018Phytomedicine27 citations
Semantic Scholar
Protective Effects of Nootkatone on Renal Inflammation, Apoptosis, and Fibrosis in a Unilateral Ureteral Obstructive Mouse Model
Chang-Mu Chen, Chen-Yu Lin, Yao-Pang Chung, Chia-Hung Liu +4 more
2021Nutrients26 citations Open access
Semantic Scholar
The covalent CDK7 inhibitor THZ1 enhances temsirolimus-induced cytotoxicity via autophagy suppression in human renal cell carcinoma.
Po-Ming Chow, Shing-Hwa Liu, Yu-Wei Chang, Kuan-Lin Kuo +2 more
2019Cancer Letters25 citations
Semantic Scholar
Role of Calbindin-D28k in Diabetes-Associated Advanced Glycation End-Products-Induced Renal Proximal Tubule Cell Injury
Kuo-How Huang, Siao-Syun Guan, Weijye Lin, Cheng-Tien Wu +3 more
2019Cells25 citations Open access
Semantic Scholar
PR-619, a General Inhibitor of Deubiquitylating Enzymes, Diminishes Cisplatin Resistance in Urothelial Carcinoma Cells through the Suppression of c-Myc: An In Vitro and In Vivo Study
Fu-Shun Hsu, Wei-Chou Lin, Kuan-Lin Kuo, Yen-Ling Chiu +9 more
2021International Journal of Molecular Sciences24 citations Open access
Semantic Scholar
Prevention of acute kidney injury by low intensity pulsed ultrasound via anti-inflammation and anti-apoptosis
Chih-Kang Chiang, Jui-Zhi Loh, Ting-hua Yang, Kuo-Tong Huang +4 more
2020Scientific Reports24 citations Open access
Semantic Scholar
The down-regulation of XBP1, an unfolded protein response effector, promotes acute kidney injury to chronic kidney disease transition
Jia-Huang Chen, Chia-Hsien Wu, J.-R. Jheng, Chia-Ter Chao +4 more
2022Journal of Biomedical Sciences23 citations Open access
Semantic Scholar
Therapeutic effect of quercetin polymeric nanoparticles on ischemia/reperfusion-induced acute kidney injury in mice.
Kuo-Tong Huang, Cheng-Tien Wu, Yung-Tin Chang, F. Ho +2 more
2022Biochemical and Biophysical Research Communications - BBRC23 citations
Semantic Scholar
Hypoxia Induced by Cobalt Chloride Triggers Autophagic Apoptosis of Human and Mouse Drug-Resistant Glioblastoma Cells through Targeting the PI3K-AKT-mTOR Signaling Pathway
Yuan-Wen Lee, Y. Cherng, Shun-Tai Yang, Shing-Hwa Liu +2 more
2021Oxidative Medicine and Cellular Longevity23 citations Open access
Semantic Scholar
Honokiol Induces Autophagic Apoptosis in Neuroblastoma Cells through a P53-Dependent Pathway.
Ming-Chung Lin, Yuan-Wen Lee, Yuan-Yun Tseng, Yung-Wei Lin +3 more
2019The American Journal of Chinese Medicine23 citations
Semantic Scholar
Safety evaluation of water extract of Gastrodia elata Blume: Genotoxicity and 28-day oral toxicity studies.
Kuan-Hung Lu, G. Ou, Hui-Ping Chang, Wei-Cheng Chen +2 more
2020Regulatory toxicology and pharmacology : RTP22 citations
Semantic Scholar
Trifluoperazine, an Antipsychotic Drug, Effectively Reduces Drug Resistance in Cisplatin-Resistant Urothelial Carcinoma Cells via Suppressing Bcl-xL: An In Vitro and In Vivo Study
Kuan-Lin Kuo, Shing-Hwa Liu, Wei-Chou Lin, Fu-Shun Hsu +8 more
2019International Journal of Molecular Sciences22 citations Open access
Semantic Scholar
Resveratrol Alleviates Advanced Glycation End-Products-Related Renal Dysfunction in D-Galactose-Induced Aging Mice
Kuo-Cheng Lan, Pei-Jin Peng, Ting-Yu Chang, Shing-Hwa Liu
2023Metabolites21 citations Open access
Semantic Scholar
Analysis of the Necrosis-Inducing Components of the Venom of Naja atra and Assessment of the Neutralization Ability of Freeze-Dried Antivenom
Cheng-Hsuan Ho, Liao-Chun Chiang, Yan-Chiao Mao, Kuo-Cheng Lan +10 more
2021Toxins21 citations Open access
Semantic Scholar
Inhibition of Indoxyl Sulfate-Induced Reactive Oxygen Species-Related Ferroptosis Alleviates Renal Cell Injury In Vitro and Chronic Kidney Disease Progression In Vivo
Li-Ting Tsai, Te I. Weng, Ting-Yu Chang, Kuo-Cheng Lan +2 more
2023Antioxidants18 citations Open access
Semantic Scholar
Genotoxicity and 28-day repeated dose oral toxicity study of garlic essential oil in mice
Yu-En Lin, Mengxiang Lin, Ti-Yen Yeh, Yi-Syuan Lai +5 more
2022Journal of Traditional and Complementary Medicine18 citations Open access
Semantic Scholar
Involvement of AMPKα and MAPK-ERK/-JNK Signals in Docetaxel-Induced Human Tongue Squamous Cell Carcinoma Cell Apoptosis
Chin-Chuan Su, Jhe-Wei Lin, K.-Y. Chang, Cheng-Tien Wu +6 more
2022International Journal of Molecular Sciences18 citations Open access
Semantic Scholar
Biomechanical and tomographic differences in the microarchitecture and strength of trabecular and cortical bone in the early stage of male osteoporosis
Poh-Shiow Yeh, Yuan-Wen Lee, W. Chang, Weu Wang +3 more
2019PLoS ONE18 citations Open access
Semantic Scholar
The UCHL5 inhibitor b-AP15 overcomes cisplatin resistance via suppression of cancer stemness in urothelial carcinoma
Po-Ming Chow, Jun-Ren Dong, Yu-Wei Chang, Kuan-Lin Kuo +3 more
2022Molecular Therapy: Oncolytics17 citations Open access
Semantic Scholar
4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene, a Major Active Metabolite of Bisphenol A, Triggers Pancreatic β-Cell Death via a JNK/AMPKα Activation-Regulated Endoplasmic Reticulum Stress-Mediated Apoptotic Pathway
Cheng-Chin Huang, Ching-Yao Yang, Chin-Chuan Su, Kai-Min Fang +7 more
2021International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
Effects of Chitosan Oligosaccharide on Plasma and Hepatic Lipid Metabolism and Liver Histomorphology in Normal Sprague-Dawley Rats
Shing-Hwa Liu, Rui-Yi Chen, Meng-Tsan Chiang
2020Marine Drugs17 citations Open access
Semantic Scholar
CDK7 inhibition by THZ1 suppresses cancer stemness in both chemonaïve and chemoresistant urothelial carcinoma via the hedgehog signaling pathway.
Po-Ming Chow, Yu-Wei Chang, Kuan-Lin Kuo, Wei-Chou Lin +2 more
2021Cancer Letters16 citations
Semantic Scholar

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Cheng-Tien Wu×11
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Kuan-I. Lee×9
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Chin-Chuan Su×9
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Ya-Wen Chen×8
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Siao-Syun Guan×7

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