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C. Guay · SciRah

Researcher profile · Semantic Scholar

C. Guay

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C. Guay — researcher profile on SciRah

h-index: 26
Works: 53
Citations: 3,883

Most-cited papers

Human polymorphism at microRNAs and microRNA target sites.
Liuqing Yang, Chun-Ru Lin, Chunyu Jin, Joy C. Yang +165 more
2013605 citations Open access
Semantic Scholar
Circulating microRNAs as novel biomarkers for diabetes mellitus
C. Guay, R. Regazzi
2013Nature Reviews Endocrinology561 citations Open access
Semantic Scholar
Diabetes mellitus, a microRNA-related disease?
C. Guay, E. Roggli, Valeria Nesca, Cécile Jacovetti +1 more
2011Translational research : the journal of laboratory and clinical medicine307 citations
Semantic Scholar
Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development.
C. Guay, J. Kruit, S. Rome, V. Menoud +13 more
2019Cell Metabolism250 citations Open access
Semantic Scholar
Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes
Valeria Nesca, C. Guay, Cécile Jacovetti, V. Menoud +4 more
2013Diabetologia218 citations Open access
Semantic Scholar
Exosomes as new players in metabolic organ cross‐talk
C. Guay, R. Regazzi
2017Diabetes, obesity and metabolism210 citations Open access
Semantic Scholar
Circular RNAs as novel regulators of β-cell functions in normal and disease conditions
Lisa Stoll, J. Sobel, Adriana Rodríguez-Trejo, C. Guay +5 more
2018Molecular Metabolism188 citations Open access
Semantic Scholar
Exosome-like vesicles released from lipid-induced insulin-resistant muscles modulate gene expression and proliferation of beta recipient cells in mice
A. Jalabert, G. Vial, C. Guay, O. Wiklander +12 more
2016Diabetologia170 citations Open access
Semantic Scholar
A Role for ATP-Citrate Lyase, Malic Enzyme, and Pyruvate/Citrate Cycling in Glucose-induced Insulin Secretion*
C. Guay, S. R. Murthy Madiraju, Alexandre Aumais, E. Joly +1 more
2007Journal of Biological Chemistry159 citations Open access
Semantic Scholar
Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells
C. Guay, V. Menoud, S. Rome, R. Regazzi
2015Cell Communication and Signaling154 citations Open access
Semantic Scholar
Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling
C. Nolan, J. Leahy, V. Delghingaro-Augusto, J. Moibi +12 more
2006Diabetologia147 citations Open access
Semantic Scholar
Postnatal β-cell maturation is associated with islet-specific microRNA changes induced by nutrient shifts at weaning
Cécile Jacovetti, S. Matkovich, Adriana Rodríguez-Trejo, C. Guay +1 more
2015Nature Communications100 citations Open access
Semantic Scholar
Emerging roles of non‐coding RNAs in pancreatic β‐cell function and dysfunction
C. Guay, Cécile Jacovetti, Valeria Nesca, A. Motterle +2 more
2012Diabetes, obesity and metabolism95 citations Open access
Semantic Scholar
Adipose Triglyceride Lipase Is Implicated in Fuel- and Non-fuel-stimulated Insulin Secretion*
M. Peyot, C. Guay, M. Latour, J. Lamontagne +9 more
2009Journal of Biological Chemistry84 citations Open access
Semantic Scholar
A circular RNA generated from an intron of the insulin gene controls insulin secretion
Lisa Stoll, Adriana Rodríguez-Trejo, C. Guay, F. Brozzi +17 more
2020Nature Communications82 citations Open access
Semantic Scholar
Role of islet microRNAs in diabetes: which model for which question?
C. Guay, R. Regazzi
2015Diabetologia48 citations Open access
Semantic Scholar
Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets
K. Tugay, C. Guay, A. C. Marques, F. Allagnat +4 more
2015Diabetologia47 citations Open access
Semantic Scholar
PIWI-interacting RNAs as novel regulators of pancreatic beta cell function
I. Hénaoui, Cécile Jacovetti, Inês Guerra Mollet, C. Guay +3 more
2017Diabetologia46 citations Open access
Semantic Scholar
New emerging tasks for microRNAs in the control of β-cell activities.
C. Guay, R. Regazzi
2016Biochimica et Biophysica Acta46 citations Open access
Semantic Scholar
A Role for Cytosolic Isocitrate Dehydrogenase as a Negative Regulator of Glucose Signaling for Insulin Secretion in Pancreatic ß-Cells
C. Guay, E. Joly, É. Pepin, A. Barbeau +5 more
2013PLoS ONE46 citations Open access
Semantic Scholar
Contribution of the Long Noncoding RNA H19 to β-Cell Mass Expansion in Neonatal and Adult Rodents
C. Sánchez-Parra, Cécile Jacovetti, O. Dumortier, Kai-Lun Lee +6 more
2018Diabetes44 citations Open access
Semantic Scholar
The GTPase Rab37 Participates in the Control of Insulin Exocytosis
Sanda Ljubicic, P. Bezzi, S. Brajkovic, Valeria Nesca +5 more
2013PLoS ONE36 citations Open access
Semantic Scholar
MicroRNAs modulate core-clock gene expression in pancreatic islets during early postnatal life in rats
Cécile Jacovetti, Adriana Rodríguez-Trejo, C. Guay, J. Sobel +5 more
2017Diabetologia30 citations Open access
Semantic Scholar
MicroRNAs and the functional β cell mass: For better or worse.
C. Guay, Romano Regazzi
2015Diabetes & Metabolism29 citations Open access
Semantic Scholar
Small RNAs derived from tRNA fragmentation regulate the functional maturation of neonatal β cells.
M. B. Bayazit, Cécile Jacovetti, C. Cosentino, J. Sobel +6 more
2022Cell Reports26 citations Open access
Semantic Scholar
Short‐chain 3‐hydroxyacyl‐CoA dehydrogenase is a negative regulator of insulin secretion in response to fuel and non‐fuel stimuli in INS832/13 β‐cells
É. Pepin, C. Guay, V. Delghingaro-Augusto, E. Joly +2 more
2010Journal of Diabetes26 citations Open access
Semantic Scholar
The mitochondrial tRNA-derived fragment, mt-tRF-LeuTAA, couples mitochondrial metabolism to insulin secretion
Cécile Jacovetti, C. Donnelly, V. Menoud, M. Suleiman +8 more
2024Molecular Metabolism15 citations Open access
Semantic Scholar
Circulating Noncoding RNAs as Candidate Biomarkers of Endocrine and Metabolic Diseases
G. Sebastiani, C. Guay, M. Latreille
2018International Journal of Endocrinology15 citations Open access
Semantic Scholar
Identification and Characterization of microRNAs Associated With Human β‐Cell Loss in a Mouse Model
R. Roat, M. M. Hossain, J. Christopherson, C. Free +4 more
2017American Journal of Transplantation15 citations Open access
Semantic Scholar
Roles of Noncoding RNAs in Islet Biology
C. Guay, Cécile Jacovetti, M. B. Bayazit, F. Brozzi +3 more
2020Comprehensive Physiology13 citations Open access
Semantic Scholar
Excretion of norsteroids' phase II metabolites of different origin in human.
C. Guay, D. Goudreault, W. Schänzer, U. Flenker +1 more
2009Steroids13 citations
Semantic Scholar
tRNA-derived fragments in T lymphocyte–beta cell crosstalk and in type 1 diabetes pathogenesis in NOD mice
F. Brozzi, Cécile Jacovetti, Cristina Cosentino, V. Menoud +7 more
2024Diabetologia11 citations Open access
Semantic Scholar
A surrogate of Roux-en-Y gastric bypass (the enterogastro anastomosis surgery) regulates multiple beta-cell pathways during resolution of diabetes in ob/ob mice
C. Amouyal, J. Castel, C. Guay, A. Lacombe +15 more
2020EBioMedicine10 citations Open access
Semantic Scholar
Scrt1, a transcriptional regulator of β-cell proliferation identified by differential chromatin accessibility during islet maturation
J. Sobel, C. Guay, O. Elhanani, Adriana Rodríguez-Trejo +5 more
2021Scientific Reports8 citations Open access
Semantic Scholar
Na+/Ca2+ Exchanger a Druggable Target to Promote β-Cell Proliferation and Function
J. Papin, F. P. Zummo, Nathalie Pachera, C. Guay +3 more
2018Journal of the Endocrine Society7 citations Open access
Semantic Scholar
Comprehensive sequencing profile and functional analysis of IsomiRs in human pancreatic islets and beta cells
Stefano Auddino, Elena Aiello, G. Grieco, D. Fignani +20 more
2025Diabetologia6 citations Open access
Semantic Scholar
Circulating miRNA‐150‐5p is associated with immune‐mediated early β‐cell loss in a humanized mouse model
R. Roat, M. M. Hossain, J. Christopherson, C. Free +3 more
2018Xenotransplantation6 citations
Semantic Scholar
5’tRNA-derived fragments modulate β-cell homeostasis and islet macrophage activation in type 2 diabetes
Cristina Cosentino, Rémy Klein, V. Menoud, C. Guay +19 more
2026Nature Communications4 citations Open access
Semantic Scholar
Loss-of-function of the long non-coding RNA A830019P07Rik in mice does not affect insulin expression and secretion
C. Guay, Baroj Abdulkarim, J. Tan, Gilles Dubuis +5 more
2020Scientific Reports3 citations Open access
Semantic Scholar
Correction: The GTPase Rab37 Participates in the Control of Insulin Exocytosis
Sanda Ljubicic, P. Bezzi, S. Brajkovic, Valeria Nesca +5 more
2013PLoS ONE2 citations Open access
Semantic Scholar
Adipose triglyceride lipase is implicated in fuel non-fuel stimulated insulin secretion
M. Peyot, C. Guay, M. Latour, J. Lamontagne +8 more
20092 citations
Semantic Scholar
Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development
Shagun Poddar, F. Brozzi, Cristina Cosentino, Cécile Jacovetti +3 more
2025bioRxiv1 citations Open access
Semantic Scholar
Publisher Correction: Loss-of-function of the long non-coding RNA A830019P07Rik in mice does not affect insulin expression and secretion
C. Guay, Baroj Abdulkarim, J. Tan, Gilles Dubuis +5 more
2020Scientific Reports1 citations Open access
Semantic Scholar
Chromatin accessibility variations across pancreatic islet maturation
J. Sobel, C. Guay, Adriana Rodríguez-Trejo, Lisa Stoll +2 more
2019bioRxiv1 citations Open access
Semantic Scholar
Small RNA profiling reveals inflammatory and mitochondrial changes in aging β cells and islet macrophages
C. Guay, Jérôme Perrard, Eleonora Mangano, V. Menoud +10 more
2026Communications Biology0 citations Open access
Semantic Scholar
5’tRNA-derived fragments modulate β-cell homeostasis and islet macrophage activation in type 2 diabetes
Cristina Cosentino, Rémy Klein, V. Menoud, C. Guay +19 more
2025bioRxiv0 citations Open access
Semantic Scholar
Small non-coding RNA profiling reveals inflammatory and mitochondrial related changes in aging β-cells and islet macrophages
C. Guay, Jérôme Perrard, Eleonora Mangano, V. Menoud +8 more
2025bioRxiv0 citations Open access
Semantic Scholar
The MIME-seq technique allows to monitor the interaction of small non-coding RNAs with Argonaute proteins and their transfer to other cells
Jérôme Perrard, C. Guay, N. Zanou, Romano Regazzi
2025bioRxiv0 citations Open access
Semantic Scholar
Lymphocyte-derived exosomal microRNAs promote pancreatic β-cell death and may contribute to type 1 diabetes development Running title: Role of exosomal microRNAs in type 1 diabetes
C. Guay, J. Kruit, Sophie Rome, V. Menoud +15 more
20180 citations
Semantic Scholar
miRNAs transferred by exosomes from T lymphocytes to beta cells contribute to type 1 diabetes development
C. Guay, J. Kruit, S. Rome, V. Menoud +4 more
20170 citations
Semantic Scholar

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Cécile Jacovetti×13
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