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N. Fernández · SciRah

Researcher profile · Semantic Scholar

N. Fernández

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N. Fernández — researcher profile on SciRah

h-index: 20
Works: 41
Citations: 856

Most-cited papers

Mepyramine, a Histamine H1 Receptor Inverse Agonist, Binds Preferentially to a G Protein-coupled Form of the Receptor and Sequesters G Protein*
C. Fitzsimons, F. Monczor, N. Fernández, C. Shayo +1 more
2004Journal of Biological Chemistry57 citations Open access
Semantic Scholar
Histamine H2 receptor desensitization: involvement of a select array of G protein-coupled receptor kinases.
C. Shayo, N. Fernández, B. L. Legnazzi, F. Monczor +3 more
2001Molecular Pharmacology55 citations Open access
Semantic Scholar
Current Knowledge and Perspectives on Histamine H1 and H2 Receptor Pharmacology: Functional Selectivity, Receptor Crosstalk, and Repositioning of Classic Histaminergic Ligands
F. Monczor, N. Fernández
2016Molecular Pharmacology51 citations
Semantic Scholar
Tiotidine, a histamine H2 receptor inverse agonist that binds with high affinity to an inactive G-protein-coupled form of the receptor. Experimental support for the cubic ternary complex model.
F. Monczor, N. Fernández, B. L. Legnazzi, M. Riveiro +3 more
2003Molecular Pharmacology48 citations Open access
Semantic Scholar
G2/M Cell Cycle Arrest and Tumor Selective Apoptosis of Acute Leukemia Cells by a Promising Benzophenone Thiosemicarbazone Compound
Maia Cabrera, N. Gómez, Federico Remes Lenicov, Emiliana B. Echeverría +4 more
2015PLoS ONE40 citations Open access
Semantic Scholar
Oligodendrocyte differentiation and signaling after transferrin internalization: a mechanism of action.
M. Pérez, N. Fernández, J. Pasquini
2013Experimental Neurology38 citations Open access
Semantic Scholar
Expression of a G Protein-coupled Receptor (GPCR) Leads to Attenuation of Signaling by Other GPCRs
M. R. Tubio, N. Fernández, C. Fitzsimons, S. Copsel +4 more
2010Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Physiological implications of biased signaling at histamine H2 receptors
Natalia Alonso, C. Zappia, Maia Cabrera, C. Davio +3 more
2015Frontiers in Pharmacology37 citations Open access
Semantic Scholar
Roles of Phosphorylation-dependent and -independent Mechanisms in the Regulation of Histamine H2 Receptor by G Protein-coupled Receptor Kinase 2*
N. Fernández, Federico L Gottardo, M. N. Alonso, F. Monczor +2 more
2011Journal of Biological Chemistry34 citations Open access
Semantic Scholar
Hexachlorobenzene modulates the crosstalk between the aryl hydrocarbon receptor and transforming growth factor-β1 signaling, enhancing human breast cancer cell migration and invasion.
N. Miret, Carolina A. Pontillo, C. Ventura, Alejandro Carozzo +5 more
2016Toxicology32 citations Open access
Semantic Scholar
Cross-Desensitization and Cointernalization of H1 and H2 Histamine Receptors Reveal New Insights into Histamine Signal Integration
Natalia Alonso, N. Fernández, C. Notcovich, F. Monczor +5 more
2013Molecular Pharmacology31 citations Open access
Semantic Scholar
Reduction of G protein-coupled receptor kinase 2 expression in U-937 cells attenuates H2 histamine receptor desensitization and induces cell maturation.
N. Fernández, F. Monczor, B. Lemos, C. Notcovich +3 more
2002Molecular Pharmacology31 citations Open access
Semantic Scholar
Rapid desensitization and slow recovery of the cyclic AMP response mediated by histamine H(2) receptors in the U937 cell line.
Bibiana Lemos Legnazzi, C. Shayo, F. Monczor, M. E. Martín +4 more
2000Biochemical Pharmacology26 citations Open access
Semantic Scholar
Pharmacological Rac1 inhibitors with selective apoptotic activity in human acute leukemic cell lines
Maia Cabrera, Emiliana B. Echeverría, F. R. Lenicov, G. Cardama +4 more
2017OncoTarget24 citations Open access
Semantic Scholar
Validation of commercial Mas receptor antibodies for utilization in Western Blotting, immunofluorescence and immunohistochemistry studies
V. Burghi, N. Fernández, Y. Gándola, V. G. Piazza +7 more
2017PLoS ONE23 citations Open access
Semantic Scholar
The time-course of cyclic AMP signaling is critical for leukemia U-937 cell differentiation.
C. Shayo, B. L. Legnazzi, F. Monczor, N. Fernández +3 more
2004Biochemical and Biophysical Research Communications - BBRC23 citations Open access
Semantic Scholar
Signal transduction mechanism of biased ligands at histamine H2 receptors.
Natalia Alonso, F. Monczor, Emiliana B. Echeverría, C. Davio +2 more
2014Biochemical Journal22 citations Open access
Semantic Scholar
Histamine H2 Receptor Trafficking: Role of Arrestin, Dynamin, and Clathrin in Histamine H2 Receptor Internalization
N. Fernández, F. Monczor, A. Baldi, C. Davio +1 more
2008Molecular Pharmacology22 citations Open access
Semantic Scholar
Histamine H2 receptor overexpression induces U937 cell differentiation despite triggered mechanisms to attenuate cAMP signalling.
F. Monczor, N. Fernández, Eugenia Riveiro, A. Mladovan +3 more
2006Biochemical Pharmacology21 citations Open access
Semantic Scholar
Antihistaminergics and inverse agonism: potential therapeutic applications.
F. Monczor, N. Fernández, C. Fitzsimons, C. Shayo +1 more
2013European Journal of Pharmacology20 citations Open access
Semantic Scholar
Dual Role of cAMP in the Transcriptional Regulation of Multidrug Resistance-Associated Protein 4 (MRP4) in Pancreatic Adenocarcinoma Cell Lines
Alejandro Carozzo, F. Diez, N. Gómez, Maia Cabrera +3 more
2015PLoS ONE19 citations Open access
Semantic Scholar
PI3K pathway is involved in ERK signaling cascade activation by histamine H2R agonist in HEK293T cells.
Natalia Alonso, Antonela Diaz Nebreda, F. Monczor, J. Gutkind +3 more
2016Biochimica et Biophysica Acta18 citations Open access
Semantic Scholar
Participation of Gαi-Adenylate Cyclase and ERK1/2 in Mas Receptor Signaling Pathways
V. Burghi, Emiliana B. Echeverría, M. Sosa, D. Quiroga +5 more
2019Frontiers in Pharmacology16 citations Open access
Semantic Scholar
Involvement of histamine H1 and H2 receptor inverse agonists in receptor's crossregulation
Antonela Díaz Nebreda, C. Zappia, Angela Rodríguez González, A. Sahores +6 more
2019European Journal of Pharmacology16 citations Open access
Semantic Scholar
Effects of histamine H1 receptor signaling on glucocorticoid receptor activity. Role of canonical and non-canonical pathways
C. Zappia, Gina Granja-Galeano, N. Fernández, C. Shayo +3 more
2015Scientific Reports15 citations Open access
Semantic Scholar
Antihistamines Potentiate Dexamethasone Anti-Inflammatory Effects. Impact on Glucocorticoid Receptor-Mediated Expression of Inflammation-Related Genes
C. Zappia, Valeria Torralba-Agu, Emiliana B. Echeverría, C. Fitzsimons +2 more
2021Cells13 citations Open access
Semantic Scholar
The Regulator of G Protein Signaling Homologous Domain of G Protein-Coupled Receptor Kinase 2 Mediates Short-Term Desensitization of β3-Adrenergic Receptor
Emiliana B. Echeverría, Maia Cabrera, V. Burghi, M. Sosa +6 more
2020Frontiers in Pharmacology12 citations Open access
Semantic Scholar
Biased agonism at histamine H1 receptor: desensitization, internalization and MAPK activation triggered by antihistamines.
V. Burghi, Emiliana B. Echeverría, C. Zappia, Antonela Díaz Nebreda +6 more
2021European Journal of Pharmacology11 citations Open access
Semantic Scholar
Histamine H2 Receptor in Blood Cells: A Suitable Target for the Treatment of Acute Myeloid Leukemia.
F. Monczor, S. Copsel, N. Fernández, C. Davio +1 more
2016Handbook of Experimental Pharmacology11 citations Open access
Semantic Scholar
Azelastine potentiates antiasthmatic dexamethasone effect on a murine asthma model
C. Zappia, A. Soto, Gina Granja-Galeano, I. Fenoy +6 more
2019Pharmacology Research & Perspectives10 citations Open access
Semantic Scholar
Identification of inhibitors of the RGS homology domain of GRK2 by docking-based virtual screening.
Emiliana B. Echeverría, Ana J. Velez Rueda, Maia Cabrera, Ezequiel I. Juritz +5 more
2019Life Science10 citations Open access
Semantic Scholar
MRP4/ABCC4 expression is regulated by histamine in acute myeloid leukemia cells, determining cAMP efflux
Á. Rodríguez González, A. Sahores, Antonela Díaz-Nebreda, A. Yaneff +6 more
2020The FEBS Journal8 citations Open access
Semantic Scholar
AT1 receptor blockade delays postlactational mammary gland involution: a novel role for the renin angiotensin system
Karen A. Nahmod, T. Walther, Nadia Cambados, N. Fernández +12 more
2012The FASEB Journal8 citations
Semantic Scholar
Histamine H 2 Receptor Trafficking : Role of Arrestin , Dynamin , and Clathrin in Histamine H 2 Receptor Internalization
N. Fernández, F. Monczor, A. Baldi, C. Davio +1 more
20088 citations
Semantic Scholar
Effect of mutation of Phe 2436.44 of the histamine H2 receptor on cimetidine and ranitidine mechanism of action
Gina Granja-Galeano, C. Zappia, Lucas E. Fabián, C. Davio +3 more
2017Biochemical Pharmacology4 citations Open access
Semantic Scholar
Lipid Goals in Diabetic Patients. Clinical Implications after Application of a New Formula for LDL-cholesterol Calculation
W. Masson, M. Huerín, M. Lobo, G. Masson +6 more
2020Revista Argentina de Cardiología2 citations
Semantic Scholar
Regulatory mechanisms underlying GKR2 levels in U937 cells: evidence for GRK3 involvement.
N. Fernández, F. Monczor, M. R. Tubio, C. Shayo +1 more
2007Biochemical Pharmacology2 citations Open access
Semantic Scholar
Abstract P318: Signaling Pathways Triggered by the Mas Receptor
V. Burghi, Emiliana B. Echeverría, D. Quiroga, M. Muñoz +2 more
2017HYPERTENSION1 citations
Semantic Scholar
O3‐09‐05: NMDA receptor and PSD‐95 expression in Alzheimer's disease play a role in postsynaptic alterations of frontal and cingulate cortex related to some clinical scores
G. Leuba, A. Vernay, R. Kraftsik, S. Joray +3 more
20121 citations
Semantic Scholar
P4‐019: Postsynaptic protein PSD‐95 expression is correlated to clinical indexes in the anterior cingulate and frontal cortex of Alzheimer's disease cases
G. Leuba, T. Volonakis, N. Fernández, S. Joray +3 more
20110 citations
Semantic Scholar
UvA-DARE (Digital Academic Repository) CB1 receptor expression and signaling are required for dexamethasone-induced aversive memory consolidation
Gina Granja-Galeano, A. P. Domínguez Rubio, C. Zappia, M. Wolfson +8 more
0 citations
Semantic Scholar

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C. Davio×30
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F. Monczor×29
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C. Shayo×27
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A. Baldi×9
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Emiliana B. Echeverría

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