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Maike Frye · SciRah

Researcher profile · Semantic Scholar

Maike Frye

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Maike Frye — researcher profile on SciRah

h-index: 22
Works: 43
Citations: 2,541

Most-cited papers

Leukocyte extravasation and vascular permeability are each controlled in vivo by different tyrosine residues of VE-cadherin
Florian Wessel, M. Winderlich, M. Holm, Maike Frye +8 more
2014Nature Immunology340 citations
Semantic Scholar
Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia
A. Greinacher, K. Selleng, R. Palankar, J. Wesche +27 more
2021Blood258 citations Open access
Semantic Scholar
Integrin β1 controls VE-cadherin localization and blood vessel stability
Hiroyuki Yamamoto, M. Ehling, Katsuhiro Kato, K. Kanai +6 more
2015Nature Communications219 citations Open access
Semantic Scholar
Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin
Maike Frye, Martina Dierkes, Verena Küppers, Matthias Vockel +8 more
2015Journal of Experimental Medicine211 citations Open access
Semantic Scholar
Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo
Andre Broermann, M. Winderlich, Helena Block, Maike Frye +7 more
2011Journal of Experimental Medicine207 citations Open access
Semantic Scholar
Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature.
Ji-Kui Shen, Maike Frye, B. Lee, Jessica L. Reinardy +14 more
2014Journal of Clinical Investigation206 citations Open access
Semantic Scholar
The Importance of Mechanical Forces for in vitro Endothelial Cell Biology
Emma J. Gordon, L. Schimmel, Maike Frye
2020Frontiers in Physiology159 citations Open access
Semantic Scholar
Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program
Maike Frye, Andrea Taddei, Cathrin Dierkes, I. Martinez-Corral +10 more
2018Nature Communications147 citations Open access
Semantic Scholar
Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation
H. Englert, C. Rangaswamy, Carsten Deppermann, J. Sperhake +16 more
2020bioRxiv89 citations Open access
Semantic Scholar
Disturbed lipid and amino acid metabolisms in COVID-19 patients
M. Masoodi, M. Peschka, S. Schmiedel, Munif Haddad +7 more
2022Journal of molecular medicine73 citations Open access
Semantic Scholar
Heterogeneity in VEGFR3 levels drives lymphatic vessel hyperplasia through cell-autonomous and non-cell-autonomous mechanisms
Yan Zhang, Maria H. Ulvmar, L. Stanczuk, I. Martinez-Corral +3 more
2018Nature Communications71 citations Open access
Semantic Scholar
Repetitive Antigen Responses of LDL-Reactive CD4+ T Cells Induce Tr1 Cell–Mediated Immune Tolerance
R. Mailer, S. Konrath, Lydia Zhan, Hanna Thode +5 more
2023Arteriosclerosis, Thrombosis and Vascular Biology67 citations Open access
Semantic Scholar
Targeting NETs using dual-active DNase1 variants
H. Englert, J. Göbel, D. Khong, M. Omidi +13 more
2023Frontiers in Immunology54 citations Open access
Semantic Scholar
EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity
Maike Frye, Simon Stritt, H. Ortsäter, Magda N. Hernández Vásquez +7 more
2020eLife47 citations Open access
Semantic Scholar
Identification of the factor XII contact activation site enables sensitive coagulation diagnostics
Marco Heestermans, C. Naudin, R. Mailer, S. Konrath +16 more
2021Nature Communications39 citations Open access
Semantic Scholar
A Thromboxane A2 Receptor-Driven COX-2–Dependent Feedback Loop That Affects Endothelial Homeostasis and Angiogenesis
Robert Eckenstaler, A. Ripperger, Michael Hauke, Markus Petermann +8 more
2022Arteriosclerosis, Thrombosis and Vascular Biology35 citations Open access
Semantic Scholar
Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate.
R. Mailer, M. Allende, Marco Heestermans, M. Schweizer +16 more
2020Blood33 citations Open access
Semantic Scholar
Erratum to: Vegfr3-CreERT2 mouse, a new genetic tool for targeting the lymphatic system
I. Martinez-Corral, L. Stanczuk, Maike Frye, Maria H. Ulvmar +4 more
2016Angiogenesis31 citations Open access
Semantic Scholar
Cutting Edge: Endothelial-Specific Gene Ablation of CD99L2 Impairs Leukocyte Extravasation In Vivo
Ruth Seelige, Christiane Natsch, S. März, Ding Jing +3 more
2013Journal of Immunology31 citations Open access
Semantic Scholar
Vegfr3-CreERT2 mouse, a new genetic tool for targeting the lymphatic system
I. Martinez-Corral, L. Stanczuk, Maike Frye, Maria H. Ulvmar +4 more
2016Angiogenesis29 citations Open access
Semantic Scholar
Vascular Endothelial Receptor Tyrosine Phosphatase: Identification of Novel Substrates Related to Junctions and a Ternary Complex with EPHB4 and TIE2*
H. Drexler, Matthias Vockel, Christian Polaschegg, Maike Frye +2 more
2019Molecular & Cellular Proteomics24 citations Open access
Semantic Scholar
Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression.
Heidi Anderson, Taylor C Patch, Pavankumar N G Reddy, Elliott J. Hagedorn +19 more
2015Blood22 citations Open access
Semantic Scholar
Heparan Sulfate Expression in the Neural Crest is Essential for Mouse Cardiogenesis
Yi-Wun Pan, Christian Carbe, Sabine Kupich, Ute Pickhinke +9 more
2013Matrix Biology22 citations Open access
Semantic Scholar
Mutations in EPHB4 cause human venous valve aplasia
Oliver Lyons, James Walker, C. Seet, M. Ikram +17 more
2021JCI Insight20 citations Open access
Semantic Scholar
EVL regulates VEGF receptor‐2 internalization and signaling in developmental angiogenesis
J. Zink, Maike Frye, Timo Frömel, Claudia Carlantoni +15 more
2021EMBO Reports20 citations Open access
Semantic Scholar
Sepsis‐induced NET formation requires MYD88 but is independent of GSDMD and PAD4
H. Englert, C. Rangaswamy, Giuliano A. Kullik, M. Divivier +13 more
2024bioRxiv16 citations Open access
Semantic Scholar
Factor XII–driven coagulation traps bacterial infections
Katrin F. Nickel, Anne Jämsä, S. Konrath, Praveen Papareddy +8 more
2025Journal of Experimental Medicine14 citations Open access
Semantic Scholar
Liver damage promotes pro‐inflammatory T‐cell responses against apolipoprotein B‐100
Bastian F J Plochg, H. Englert, C. Rangaswamy, S. Konrath +9 more
2021Journal of Internal Medicine14 citations Open access
Semantic Scholar
Intrinsic coagulation pathway-mediated thrombin generation in mouse whole blood
S. Konrath, R. Mailer, M. Beerens, H. Englert +8 more
2022Frontiers in Cardiovascular Medicine11 citations Open access
Semantic Scholar
Role of the NO-GC/cGMP signaling pathway in platelet biomechanics
Aylin Balmes, Johanna G. Rodríguez, Jan Seifert, Daniel Pinto-Quintero +9 more
2023bioRxiv9 citations Open access
Semantic Scholar
The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling.
Claudia Carlantoni, L. Liekfeld, S. A. Hemkemeyer, Danny Schreier +13 more
2023Developmental Cell7 citations Open access
Semantic Scholar
Same same but different? How blood and lymphatic vessels induce cell contact inhibition
Claudia Carlantoni, L. Liekfeld, Manu Beerens, Maike Frye
2025Biochemical Society Transactions6 citations Open access
Semantic Scholar
Antiplatelet drugs do not protect from platelet-leukocyte aggregation in Coronary Artery Disease.
C. Schulte, L. Pieper, Maike Frye, C. Waldeyer +3 more
2023Journal of Thrombosis and Haemostasis6 citations Open access
Semantic Scholar
Prdm16 amplifies Notch signaling and suppresses venous lineage specification to prevent arteriovenous malformations during vascular development
J. Van Wauwe, S. Craps, KC Ashmita, Lisabel Asuncion +10 more
2021bioRxiv6 citations Open access
Semantic Scholar
Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program
Maike Frye, Andrea Taddei, Cathrin Dierkes, I. Martinez-Corral +10 more
2018Nature Communications4 citations Open access
Semantic Scholar
Neprilysin inhibition reduces microtubule detyrosination in cardiomyocytes through a cGMP-PRKG1-VASH1 axis
Moritz Meyer-Jens, Chadni Sanyal, Niels Pietsch, Sacnicte Ramirez-Rios +9 more
2026bioRxiv1 citations
Semantic Scholar
Prdm16 Amplifies Notch Signaling and Suppresses Venous Lineage Specification to Prevent Arteriovenous Malformations During Vascular Development
J. Van Wauwe, Pavithra Janarthanan, S. Craps, A. Kc +15 more
2026Arteriosclerosis, Thrombosis and Vascular Biology1 citations Open access
Semantic Scholar
A novel stent flow chamber system demonstrates reduced thrombogenicity of bioresorbable magnesium scaffolds
Monja Müller, L. Ludwig, H. Englert, K. Riedl +8 more
2024Scientific Reports1 citations Open access
Semantic Scholar
Endothelial neo-antigen expression initiates CD8⁺ T cell-driven CNS vasculitis amplified by peripheral immune challenge.
I. S. Schädlich, Dustin Nguyen, M. Thiem, Andreas Franzelin +30 more
2026Journal of Clinical Investigation0 citations Open access
Semantic Scholar
The phosphodiesterase 2A regulates lymphatic endothelial development via cGMP-mediated control of Notch signaling
Claudia Carlantoni, L. Liekfeld, S. A. Hemkemeyer, Danny Schreier +13 more
2023bioRxiv0 citations Open access
Semantic Scholar
Abstract 13973: Human iPSC-Derived Multi-Cell-Type Engineered Heart Tissues as an in vitro Model to Study Pathological Cardiac Hypertrophy
Kinga M Wrona, Alba M. Albert, D. Eckardt, C. Herbel +7 more
2022Circulation0 citations
Semantic Scholar
Expression profile of human lymphatic endothelial cells cultured on stiff (25 kPa) or soft (0.2 kPa) matrix conditions in the presence or absence of GATA2
Maike Frye
20180 citations
Semantic Scholar
Extravasation In Vivo Ablation of CD99L2 Impairs Leukocyte Cutting Edge: Endothelial-Specific Gene
Maike Frye, S. Butz, D. Vestweber, Ruth Seelige +3 more
20130 citations
Semantic Scholar
Blockade of Vascular Endothelial Protein Tyrosine Phosphatase: A Novel Approach to Stabilizing the Retinal Vasculature
Ji-Kui Shen, P. Campochiaro, Christopher P. Seidel, A. Dong +6 more
20130 citations
Semantic Scholar

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